一种宣肺败毒中药组合物多指标成分的检测方法
By combining high performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC) with a gradient elution procedure and optimizing extraction conditions, a fingerprint spectrum and content determination method for Xuanfei Baidu Granules were established. This solved the instability problem in the detection of components of Xuanfei Baidu Granules, achieved accurate control of multiple indicator components, and ensured the consistency of product quality.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHANDONG BUCHANG PHARMA
- Filing Date
- 2024-05-21
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies are insufficient to comprehensively and accurately control the content and quality of various active ingredients in Xuanfei Baidu Granules, and lack a systematic method for establishing fingerprint spectra, resulting in unstable product quality.
High performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC), combined with gradient elution procedures and characteristic index components, were used to establish a fingerprint spectrum and content determination method for Xuanfei Baidu Granules. By optimizing the extraction solvent, material-liquid ratio, and extraction time, the contents of verbenacin, verbenin, glutinin, verbascoside, isoverascoside, naringin, and glycyrrhizic acid were identified to ensure product quality consistency.
The stability and accuracy of the multi-index component detection method for Xuanfei Baidu Granules have been achieved, ensuring the intrinsic quality of the product, providing a systematic quality control means, and improving the similarity and consistency of the product components.
Smart Images
Figure CN118443846B_ABST