一种带电吸脂去白细胞滤材及其制备方法

By constructing a three-layer coating of positive, intermediate, and negative charges on the surface of meltblown nonwoven fabric, the problem of simultaneously and efficiently removing white blood cells and blood lipids from the blood in existing technologies has been solved, achieving a highly efficient blood purification effect and improving blood transfusion safety and blood resource utilization.

CN118491160BActive Publication Date: 2026-07-17ZINGKE (CHONGQING) ADVANCED MATERIALS RES INST CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZINGKE (CHONGQING) ADVANCED MATERIALS RES INST CO LTD
Filing Date
2024-05-10
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing technologies cannot efficiently remove white blood cells and blood lipids from the blood at the same time, leading to transfusion safety risks and insufficient blood resources.

Method used

A three-layer coating consisting of a positive charge layer, an intermediate layer, and a negative charge layer is constructed on the surface of meltblown nonwoven fabric. The positive charge layer adsorbs white blood cells, the negative charge layer adsorbs blood lipids, and the intermediate layer isolates the positive and negative charge layers, thereby improving charge stability.

Benefits of technology

It achieved a white blood cell removal rate of 99.83%, a red blood cell recovery rate of over 85%, and a significant improvement in blood lipid removal, thereby enhancing blood quality and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开了一种带电吸脂去白细胞滤材及其制备方法,涉及血液过滤材料技术领域,以聚丙烯酸铵类为正电改性单体,过硫酸铵为引发剂,N‑N亚甲基双丙烯酰胺为交联剂构建正电层;以丙烯酸类为单体,过硫酸钾为引发剂构建中间层;以丙烯酸与过硫酸钾反应生成的聚丙烯酸为基材包裹肝素从而达到构建负电层。本发明去白细胞滤材的白细胞去除率可以达到99.83%,红细胞回收率达到85%以上;与纯PP熔喷布相比,总胆固醇TC去除效果提升4倍左右,导致动脉粥样硬化的低密度脂蛋白胆固醇LDL‑C去除率提升7倍左右,冠心病的保护因子高密度脂蛋白胆固醇LDL‑H的去除提升至7%,能够充分去除有害物质,同时充分保留有益物质。
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