一种酰乙酯多环化合物及其药物组合物和用途
By developing ethyl ester polycyclic compounds and their drug compositions, the problem of low bioavailability of existing anti-influenza virus drugs has been solved, achieving drug efficacy with high bioavailability and long half-life, and significantly improving the therapeutic effect against influenza virus.
CN118496239BActive Publication Date: 2026-07-17NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD
- Filing Date
- 2024-04-12
- Publication Date
- 2026-07-17
AI Technical Summary
Technical Problem
Existing antiviral drugs for influenza have low bioavailability, short half-life, and low blood drug concentration, which cannot effectively meet clinical needs.
Method used
To develop an ethyl ester polycyclic compound and a pharmaceutical composition thereof, comprising the ethyl ester polycyclic compound and its isomers, a pharmaceutically acceptable salt, a solvate or an isotopic label, for use in the prevention and treatment of influenza virus infectious diseases.
Benefits of technology
It improved the bioavailability and half-life of the drug, significantly increased blood drug concentration, and demonstrated potent anti-influenza virus activity and protective effect.
✦ Generated by Eureka AI based on patent content.
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Figure CN118496239B_ABST
Abstract
本发明公开了一种酰乙酯多环化合物及其药物组合物和用途。所述的酰乙酯多环化合物如式I所示，其中X为S或Se，该化合物对于病毒感染的个体具有预防或治疗作用。
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