一种多相一体化制备三叶青提取物的方法及其在口腔护理组合物中的应用
By employing a multiphase integrated extraction process and low-temperature centrifugation technology, steroidal, polysaccharide, and flavonoid components in *Trifolium repens* are efficiently extracted and preserved. This addresses the shortcomings of existing technologies in the application of *Trifolium repens* extract in oral care products, achieving highly effective hemostatic and coagulation effects as well as prevention and treatment of various oral diseases.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- NICE ZHEJIANG TECH CO LTD
- Filing Date
- 2024-05-13
- Publication Date
- 2026-07-17
AI Technical Summary
There is a lack of effective development of using Tripterygium wilfordii extract alone in oral care products in the existing technology, and existing methods are difficult to efficiently extract and maintain the activity of multiple active ingredients of Tripterygium wilfordii.
A multiphase integrated extraction process was adopted, using dichloromethane, water and petroleum ether as three-phase extraction solvents. Combined with the addition of acetonitrile and low-temperature centrifugation technology, steroidal, polysaccharide and flavonoid components in Trifolium repens were separated to ensure efficient extraction and preservation of activity.
It achieves efficient extraction of Trifoliate Oral Extract, maintains the high activity of various components, and has excellent hemostatic and coagulation effects when added to oral care compositions. It can quickly eliminate gum bleeding, swelling and other phenomena, and effectively prevent and treat a variety of oral diseases.
Smart Images

Figure CN118512523B_ABST