一种治疗乳腺增生的中药组合物、中药制剂、制备方法和应用

By combining water extraction and alcohol extraction, the extraction route of traditional Chinese medicine was optimized, solving the problems of uneven extraction of effective components and high impurity content in traditional Chinese medicine preparations, and achieving a highly effective treatment for breast hyperplasia.

CN118526543BActive Publication Date: 2026-07-17中科宝汇(天津)生物科技有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
中科宝汇(天津)生物科技有限公司
Filing Date
2023-02-23
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing Chinese medicine extraction processes cannot maximize the extraction of effective components from each herb, resulting in inconsistent quality of the prepared Chinese medicine fluid extracts, and problems such as high impurity content and low effective substance content.

Method used

The process combines water extraction and alcohol extraction, and the extraction is carried out according to the properties of the effective components of the medicinal materials. The process includes an alcohol precipitation step, optimizes the extraction process route, maximizes the extraction of effective components and removes impurities.

Benefits of technology

It increased the content of effective ingredients in traditional Chinese medicine preparations, significantly reduced the nipple volume and serum estradiol content in mice, improved mammary gland structure, and reduced the proliferation and dilation of alveoli and ducts.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开了一种中药组合物、中药制剂、制备方法和应用,涉及中药技术领域。本发明中药组合物包括:柴胡5-15份,夏枯草5-30份,香附5-15份,丹参10-30份,醋鳖甲10-20份,浙贝母5-15份,蒲公英20-40份,鹿角片10-20份,橘核10-20份。本发明提供的中药制剂的制备方法:将醋鳖甲和鹿角片混合后经水提过程1得到水提滤液1,水提滤液1浓缩成流浸膏1;其余药材先经水提过程2得到水提滤液2,水提滤液2再经醇沉得到醇沉液,醇沉液浓缩成流浸膏2;流浸膏1和流浸膏2混合制剂获得所述中药制剂。采用本发明方法制备的中药制剂有效成分含量高,杂质少,可拓展治疗乳腺增生的药物研究。
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