一种类海胆状氧空位Ce掺杂Bi2MoO6纳米酶及其制备方法和应用

The sea urchin-like oxygen vacancy Ce-doped Bi2MoO6 nanozyme prepared by solvothermal method and H2O2 etching technology solves the problems of insufficient catalytic activity and reaction rate of existing nanozymes, and realizes efficient and sensitive detection and differentiation of neurotransmitters.

CN118527139BActive Publication Date: 2026-07-17XUZHOU MEDICAL UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
XUZHOU MEDICAL UNIVERSITY
Filing Date
2024-05-13
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing nanozymes have shortcomings in terms of catalytic activity, preparation cost, and reaction rate, especially in the detection of neurotransmitters, where their sensitivity and selectivity are insufficient, making it difficult to achieve rapid identification and differentiation.

Method used

A solvothermal method was used to prepare sea urchin-like Ce-doped Bi2MoO6 nanozymes, and oxygen-vacancy Ce-doped Bi2MoO6 nanozymes were prepared by H2O2 etching and surface remodeling technology. The excellent oxidative mimic enzyme catalytic activity was used to construct a colorimetric array sensor.

Benefits of technology

A high-catalytic-activity, low-cost nanozyme sensing array has been developed, which can rapidly and sensitively measure and identify neurotransmitters in biological fluids, providing a portable and highly selective sensing platform.

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Abstract

本发明公开了一种类海胆状氧空位Ce掺杂的Bi2MoO6纳米酶及其制备方法和应用。所述纳米酶是将钼盐、铋盐和铈盐完全溶解于乙二醇‑乙醇混合溶液中,经溶剂热反应制得类海胆状Ce掺杂Bi2MoO6,然后将类海胆状Ce掺杂Bi2MoO6经双氧水刻蚀制备而成。本发明制备方法简单、反应条件温和,所得纳米酶展现出杰出的模拟氧化酶活性,可用于高选择性的比色测定‑鉴别鼠脑中化学活性与分子结构相似的神经递质类化合物。本发明为构建高催化活性的类海胆状氧空位Ce掺杂Bi2MoO6模拟氧化酶提供了新思路,也为便携式测定与识别生物流体中化学结构相似的神经递质提供了新方法。
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