A composition having an appetite-enhancing and digestion-promoting effect, and a preparation method and use thereof

CN118542455BActive Publication Date: 2026-10-27RENHE GLOBAL (SHANGHAI) GRAND HEALTH RESEARCH INSTITUTE CO LTD
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Patent Information

Application Number
CN202410305198.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-03-18
Publication Date
2026-10-27
Estimated Expiration
2044-03-18

AI Technical Summary

Technical Problem

[0003]目前市面上现有的治理儿童偏食、挑食类产品多由常见促消化中药材制成,具有中药材特有的滋味、气味,不符合儿童味觉需求,造成不能儿童不愿自主食用,不能很好的解决儿童的食物摄入量提升的问题;且多以促进消化和排便为主,并不能很好的解决儿童腹胀问题,不能起到全面改善挑食、偏食问题

Benefits of technology

本申请添加紫苏粉、山楂果汁粉、N-乙酰氨基葡萄糖、吡啶甲酸锌复配,具有协同增效作用,能够促进消化,促进肠道蠕动,改善便秘,通过合理的搭配得到最佳的促进儿童消化功能的效果。同时调节儿童味觉障碍,提升儿童食欲,增加食物摄入种类和总摄入量,更适合儿童口味需求,能够长期食用,纠正偏食、挑食行为。

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a composition with appetite promotion and digestion promotion and a preparation method and application thereof, and relates to the field of food. The composition comprises perilla powder, hawthorn juice powder, N-acetyl glucosamine, zinc picolinic acid, a sweetening agent and a lubricant. The perilla powder is added to cooperate with the N-acetyl glucosamine to improve the problems of abdominal distension and indigestion. The hawthorn juice powder and the zinc picolinic acid are compounded to regulate the taste disorder of children, promote the appetite of children, promote the intestinal peristalsis and improve constipation. The reasonable collocation can obtain the best effect of promoting the digestion function of children, increase the food intake types and the total intake amount, is more suitable for the taste demand of children, can be long-term eaten, and can correct the picky eating behavior.
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Description

Technical Field

[0001] This invention relates to the food industry, and more particularly to a composition that enhances appetite and promotes digestion, as well as its preparation method and application. Background Technology

[0002] Picky eating, unbalanced diets, and anorexia in children can lead to insufficient daily nutrient intake. Modern medicine believes that the main physiological causes are taste disorders, weak spleen and stomach, and intestinal discomfort. Taste disorders can cause children to lose interest in eating and not enjoy the pleasure of meals, directly reducing their food intake. Weak spleen and stomach are often accompanied by diarrhea after meals, abdominal distension after eating, sallow complexion, and thin physique, leading to insufficient nutrient absorption. Intestinal discomfort often manifests as abdominal distension, gas, and constipation, indicating indigestion. Long-term picky eating, unbalanced diets, and anorexia in children can affect their growth and development, such as height and weight, seriously threatening their physical and mental health.

[0003] Currently available products on the market for treating picky eating in children are mostly made from common digestive Chinese medicinal herbs. These herbs have a unique taste and aroma that do not meet children's taste preferences, making them unwilling to consume them independently. They cannot effectively address the issue of increasing children's food intake. Furthermore, they primarily promote digestion and bowel movements, and cannot effectively solve the problem of bloating in children, nor can they comprehensively improve picky eating. Summary of the Invention

[0004] This invention provides a composition that enhances appetite and promotes digestion, as well as its preparation method and application, to address taste disorders such as picky eating and food aversion, as well as digestive problems such as bloating and constipation in children.

[0005] To address the aforementioned technical problems, one objective of this invention is to provide a composition that enhances appetite and promotes digestion, comprising the following components in parts by weight: Perilla powder: 0.1-0.22 parts; Hawthorn juice powder: 0.06-0.22 parts; N-acetylglucosamine: 0.03-0.074 parts; Zinc pyridinecarboxylate: 0.005-0.024 parts; Sweetener: 0.483-0.754 parts; Lubricant: 0.01-0.03 parts.

[0006] The perilla powder added in this application has the functions of relieving exterior syndromes and dispelling cold, regulating qi and harmonizing the stomach. It contains various flavonoids, caffeic acid, and rosmarinic acid, which can relieve gastrointestinal discomfort and promote intestinal peristalsis. Combined with N-acetylglucosamine, it synergistically improves bloating and indigestion, and increases bowel movements. Hawthorn juice powder has the effect of strengthening the stomach and eliminating food stagnation and bloating. It contains active ingredients such as organic acids, flavonoids, vitexin, polyphenols, pentacyclic triterpenoids, and alkaloids, which can stimulate appetite, increase pepsin activity, and promote digestion, resulting in a good appetite-stimulating effect. Combined with zinc picolinate, it regulates taste disorders and improves appetite.

[0007] As a preferred embodiment, the sweetener is at least one selected from maltitol, erythritol, sucralose, sorbitol, xylitol, isomaltitol, mannitol, and lactitol.

[0008] As a preferred embodiment, the sweetener comprises 0.432-0.579 parts by weight of maltitol, 0.05-0.17 parts by weight of erythritol, and 0.001-0.005 parts by weight of sucralose.

[0009] As a preferred embodiment, the lubricant is magnesium stearate.

[0010] As a preferred option, it also includes 0.001-0.009 parts by weight of edible flavoring.

[0011] To address the aforementioned technical problems, a second objective of this invention is to provide an application of a composition that enhances appetite and promotes digestion in the preparation of food, pharmaceuticals, or health products.

[0012] To address the aforementioned technical problems, a third objective of this invention is to provide a chewable tablet that enhances appetite and promotes digestion, comprising the aforementioned composition that enhances appetite and promotes digestion.

[0013] To address the aforementioned technical problems, a fourth objective of this invention is to provide a method for preparing chewable tablets that enhance appetite and promote digestion, comprising the following steps: (1) Mix sweetener and flavoring in equal increments until homogeneous to obtain a premix; (2) Place the premix, perilla powder, hawthorn juice powder, N-acetylglucosamine, zinc pyridinecarboxylate, and lubricant in a three-dimensional mixer and stir to obtain a mixture; (3) Compress the mixture into tablets and discharge them.

[0014] As a preferred embodiment, in step (2), the stirring and mixing rate is 10-20 rpm and the time is 20-40 min; in step (3), the tablet weight is 1-3 g.

[0015] Compared with the prior art, the embodiments of the present invention have the following beneficial effects: This application adds perilla powder, hawthorn juice powder, N-acetylglucosamine, and zinc picolinate, which have a synergistic effect, promoting digestion, intestinal peristalsis, and relieving constipation. Through this balanced combination, it achieves optimal results in promoting children's digestive function. Simultaneously, it regulates children's taste buds, enhances their appetite, increases the variety and total amount of food consumed, making it more suitable for children's palates and suitable for long-term consumption, correcting picky eating habits. Detailed Implementation

[0016] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0017] It is understood that the compositions described in the embodiments of the present invention can also be prepared into various suitable products by adding different food-grade acceptable excipients. These food-grade acceptable excipients include, but are not limited to, diluents, wetting agents, binders, flash-off agents, lubricants, color and flavor modifiers, solvents, solubilizers, co-solvents, emulsifiers, antioxidants, metal complexing agents, preservatives, pH adjusters, etc. Furthermore, diluents include starch, sucrose, cellulose, and inorganic salts; wetting agents include water and ethanol; binders include starch paste, dextrin, sugar, cellulose derivatives, gelatin, povidone, and polyethylene glycol; disintegrants include starch, sodium carboxymethyl starch, low-substituted hydroxypropyl cellulose, sodium bicarboxymethyl cellulose, and surfactants; lubricants include talc, calcium stearate, magnesium stearate, magnesium dodecyl sulfate, and polyethylene glycol; flavoring and coloring agents include pigments, sweeteners, flavorings, and gelling agents; solvents include water, glycerin, and ethanol; and solubilizers include Tween compounds, etc. Saturates, sulfates, sulfonates, etc.; solubilizers, including organic acids (such as citric acid) and their salts, inorganic salts, polyethylene glycol, etc.; emulsifiers, including Span derivatives, glycerol fatty acid esters, gum arabic, gelatin, agar, sodium alginate, etc.; antioxidants, including sulfites, ascorbic acid, gallic acid and their salts, etc.; metal complexing agents, including disodium ethylenediaminetetraacetate, polycarboxylic acid compounds, etc.; preservatives, including parabens, quaternary ammonium compounds, chlorhexidine acetate, etc.; pH adjusters, including hydrochloric acid, tartaric acid, acetic acid, sodium hydroxide, sodium bicarbonate, ethylenediamine, meglumine, phosphates, citrates, etc.

[0018] Examples 1-9 A chewable tablet with the effects of improving appetite and promoting digestion, the components and contents of which are shown in Table 1 below, include perilla powder, hawthorn juice powder, N-acetylglucosamine, zinc picolinate, sweetener, chocolate flavoring, and lubricant. The sweetener is at least one of maltitol, erythritol, sucralose, sorbitol, xylitol, isomaltitol, mannitol, and lactitol. The lubricant is magnesium stearate.

[0019] The preparation method of the above-mentioned chewable tablet with the effects of improving appetite and promoting digestion includes the following steps: (1) Mix sweetener and flavoring in equal increments until homogeneous to obtain a premix; (2) Place the premixed material, perilla powder, hawthorn juice powder, N-acetylglucosamine, zinc pyridinecarboxylate, and lubricant in a three-dimensional mixer and mix for 30 minutes at a stirring speed of 10 rpm. (3) The mixture is compressed into tablets using a rotary tablet press at a speed of 20 rpm, a pressure of 10 KN, a mold diameter of 14 mm, and a tablet weight of 1.0 g. After sampling and testing, the tablets are discharged after passing the test.

[0020] Table 1 - Components and content of chewable tablets in embodiments of this application Table 2 - Components and Contents in Chewable Tablets of Comparative Examples 1-7 of this Application Performance testing 1. Sweetness Preference Assessment: Ten trained tasters tasted each test sample and scored its sweetness from 1 to 5. 1 represents no sweetness or mild sweetness, 2 represents mild sweetness, 3 represents moderate sweetness, 4 represents strong sweetness, and 5 represents excessive sweetness. The assessment results are shown in Table 3 below. The chewable tablets prepared using maltitol, erythritol, and sucralose in Examples 1-5 of this application have a moderate sweetness, which can improve children's appetite. However, the sweeteners in Examples 6-7 have insufficient sweetness, resulting in lower acceptance among children.

[0021] Table 3 - Sweetness Scoring Results in Examples 1-9 of this Application 2. Abdominal distension and defecation test: 120 children aged 6-10 years who experienced 6-8 episodes of abdominal distension per month were randomly divided into 12 groups. In each group, 2 children experienced 8 episodes of abdominal distension per month, 3 children experienced 7 episodes per month, and 5 children experienced 6 episodes per month. They consumed the chewable tablets from Examples 1-5 and Comparative Examples 1-7 for 30 consecutive days, 2 tablets per day, before breakfast and dinner. The average total number of episodes of abdominal distension per person over the 30 days was recorded, including the sensation of abdominal distension, visible abdominal bloating, and abdominal pressure. Any pain was considered abdominal distension. The number of abdominal distension episodes over 30 days of consumption was recorded, and the average number for each group was recorded. 120 children aged 6-10 years with a daily bowel movement frequency of less than or equal to 0.5 were randomly divided into 12 groups. They consumed the chewable tablets of Examples 1-5 and Comparative Examples 1-7 for 30 consecutive days, 2 tablets / day, before breakfast and dinner. The number of bowel movements over 30 days was recorded. The sum of the number of bowel movements was divided by the number of days, and the proportion of children with a daily bowel movement frequency in the ranges of <0.5, 0.5-2, and >2 was counted. The test results are shown in Table 4 below.

[0022] Table 4 - Results of abdominal distension and defecation tests in the embodiments and comparative examples of this application. 3. Food intake and weight experiment: Children aged 6-10 years with poor appetite, small food intake, picky eating, etc. were randomly divided into 12 groups of 10 children each. They consumed the food for 30 consecutive days. The results are shown in Table 5 below.

[0023] Food intake: A 3-day dietary survey method was used to record the total daily food intake (including staple food, side dishes, vegetables and fruits) of each child in the 3 days before the start of the food trial and the 3 days before the end of the food trial. The average daily food intake was calculated by observing for 3 consecutive days and the change value was calculated. Weight: Measure weight before and after consumption, and calculate the change.

[0024] Table 5 - Evaluation results of food intake and body weight experiments in Examples 1-5 and Comparative Examples 1-7 of this application By comparing the schemes of Example 3 and Comparative Examples 1, 3, and 5 in Tables 4-5, it can be seen that, compared with Example 3, Comparative Example 1 uses chicken gizzard lining instead of perilla powder, Comparative Example 3 does not add N-acetylglucosamine, and Comparative Example 5 uses chicken gizzard lining instead of perilla powder and does not add N-acetylglucosamine. It can be found that the defecation and abdominal distension improvement effects of Comparative Examples 1, 3, and 5 are not significantly different and are all inferior to Example 3. It can be inferred that the N-acetylglucosamine added in this application can assist perilla powder in improving children's gastrointestinal digestion, increasing the frequency of defecation, reducing abdominal distension, improving children's appetite, and increasing food intake. However, when chicken gizzard lining is used instead of perilla powder, the addition or absence of N-acetylglucosamine does not cause any difference in the improvement of defecation or abdominal distension.

[0025] By comparing the solutions of Example 3 and Comparative Examples 2, 4, and 6 in Tables 4-5, it can be seen that, compared with Example 3, Comparative Example 2 uses perilla powder instead of hawthorn juice powder, Comparative Example 4 does not add zinc picolinate, and Comparative Example 6 uses perilla powder instead of hawthorn juice powder and does not add zinc picolinate. It can be found that the effects of Comparative Examples 2, 4, and 6 in improving defecation and abdominal distension are all worse than those of Example 3. Therefore, it can be inferred that the addition of hawthorn juice powder and zinc picolinate in this application can synergistically improve defecation and abdominal distension.

[0026] The specific embodiments described above further illustrate the purpose, technical solution, and beneficial effects of the present invention. It should be understood that the above descriptions are merely specific embodiments of the present invention and are not intended to limit the scope of protection of the present invention. In particular, it should be noted that any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention for those skilled in the art.

Claims

1. A composition having the effects of enhancing appetite and promoting digestion, characterized in that, Composed of the following components in parts by weight: Perilla powder: 0.1-0.22 parts; Hawthorn juice powder: 0.06-0.22 parts; N-acetylglucosamine: 0.03-0.074 parts; Zinc pyridinecarboxylate: 0.005-0.024 parts; Sweetener: 0.483-0.754 parts; Lubricant: 0.01-0.03 parts; Edible flavoring: 0.001-0.009 parts; The sweetener is composed of 0.432-0.579 parts by weight of maltitol, 0.05-0.17 parts by weight of erythritol and 0.001-0.005 parts by weight of sucralose; The lubricant is magnesium stearate.

2. A chewable tablet that enhances appetite and promotes digestion, characterized in that, Includes the composition as described in claim 1, which has the effects of enhancing appetite and promoting digestion.

3. A method for preparing a chewable tablet with appetite-enhancing and digestion-promoting effects as described in claim 2, characterized in that, Includes the following steps: (1) Mix sweetener and flavoring in equal increments until homogeneous to obtain a premix; (2) Place the premix, perilla powder, hawthorn juice powder, N-acetylglucosamine, zinc pyridinecarboxylate, and lubricant in a three-dimensional mixer and stir to obtain a mixture; (3) Compress the mixture into tablets and discharge them.

4. A method for preparing a chewable tablet with appetite-enhancing and digestion-promoting effects as described in claim 3, characterized in that, In step (2), the stirring and mixing rate is 10-20 rpm and the time is 20-40 min; in step (3), the tablet weight is 1-3 g.

Citation Information

Patent Citations

  • Appetizing chewing tablet and its preparation technology

    CN103055209A

  • The use of n-acetyl glucosamine as additive in milk products

    WO2004093556A1