一种负载亚硝酸钠的醇溶蛋白纳米纤维膜及其制备和应用

By treating the alcohol-soluble protein solution with a pulsed electric field and combining it with appropriate electrospinning parameters, the problem of insufficient interaction between alcohol-soluble protein and sodium nitrite was solved, and a highly efficient antibacterial alcohol-soluble protein nanofiber membrane was prepared, which is suitable for antibacterial packaging materials.

CN118621490BActive Publication Date: 2026-07-17YANGZHOU UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
YANGZHOU UNIV
Filing Date
2024-06-07
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Insufficient interaction and entanglement between alcohol-soluble proteins and sodium nitrite led to electrospinning failure, limiting the application of sodium nitrite in antibacterial materials.

Method used

A pulsed electric field was used to treat the alcohol-soluble protein solution to enhance the interaction and entanglement between alcohol-soluble protein and sodium nitrite. Combined with appropriate electrospinning parameters, alcohol-soluble protein nanofiber membranes loaded with sodium nitrite were prepared.

Benefits of technology

The electrospinning efficiency was improved, and the alcohol-soluble protein nanofiber membrane loaded with sodium nitrite exhibited high antibacterial efficiency against Staphylococcus aureus and Salmonella, making it suitable for antibacterial packaging materials.

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Abstract

本发明公开了一种负载亚硝酸钠的醇溶蛋白纳米纤维膜及其制备和应用。负载亚硝酸钠的醇溶蛋白纳米纤维膜由包含醇溶蛋白和3‑7wt%亚硝酸钠的无串珠纤维组成,所述亚硝酸钠中的钠元素在纤维上分布均匀。其制备方法包括:向醇溶蛋白溶液中加入亚硝酸钠,混匀后置于脉冲电场中处理得到静电纺丝溶液;采用静电纺丝溶液进行静电纺丝得到负载亚硝酸钠的醇溶蛋白纳米纤维膜。本发明通过有效的外加物理场(即脉冲电场)进行分子间互作强化,使得脉冲电场处理后的含有亚硝酸钠的醇溶蛋白溶液可以用于后续的静电纺丝步骤中。本发明具有来源丰富、成本低廉和环境友好等特点,且其得到的纤维膜具有较强的疏水性,可适合应用于食品智能或活性包装等领域。
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