磁分离清洗方法、装置、电子设备及可读存储介质

By capturing magnetic microparticles to the inner wall of the reaction vessel under the action of a magnetic field, and injecting cleaning fluid into the non-magnetic field area and performing interactive magnetic field stirring, the problem of poor cleaning effect caused by magnetic microparticle agglomeration is solved, and efficient magnetic microparticle cleaning is achieved.

CN118649942BActive Publication Date: 2026-07-17SHENZHEN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENZHEN UNIV
Filing Date
2024-06-18
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In traditional magnetic particle cleaning, the magnetic field causes the magnetic particles to agglomerate, resulting in unbound markers being trapped inside the magnetic particles, making it difficult to clean thoroughly and affecting the cleaning effect.

Method used

Magnetic particles are captured to the inner wall of the reaction vessel under the action of a magnetic field, then moved to a non-magnetic field area to inject cleaning fluid and are magnetically stirred in an alternating magnetic field to disperse the magnetic particles and release impurities.

Benefits of technology

It achieves high-purity separation and efficient cleaning of magnetic particles, ensuring that impurities such as unbound markers are fully removed, thus improving the magnetic separation and cleaning effect.

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Abstract

本申请适用于免疫磁分离技术领域,提供了一种磁分离清洗方法及装置,包括:在反应容器的外侧壁与磁源接触的情况下,捕获反应容器中免疫复合物的磁微粒至反应容器的内侧壁;若符合吸液条件,则执行针对反应容器内的废液的吸液操作;在吸液完成后,将反应容器移动至远离磁源关联的磁场范围的清洗区域;向反应容器内注射清洗液直至覆盖反应容器内侧壁上的磁微粒;确定反应容器内的磁微粒对应的交互磁场,并在交互磁场中,对磁微粒进行磁性搅拌,以使磁微粒由团聚状态变更为离散状态。基于此,能够实现磁微粒免疫复合物的高纯度分离和高效率清洗。
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