A multi-pass cooperative scheduling white filter and heating combined integrated blood preparation production line system

Abstract

The application discloses a kind of multi-pass cooperative scheduling filter white heat integration type blood preparation production line system, by setting artificial bag hanging area, filter white preparation area, heat sealing transmission area and fault handling area, with the aid of track interconnection, mobile filter white unit is placed in track, and according to filter white completion state self-drive to heat sealing transmission or fault handling area, each mobile filter white unit intercommunication cooperative scheduling realizes single-track sharing, not only realizes the integration of blood filter white, heat sealing, filter white abnormality identification sorting operation, also greatly improves the response capability to a large number of preparation tasks, improves the production efficiency of filter white blood product;In addition, the application separately integrates mobile power supply in mobile filter white unit, and can find charging connector to charge, not only realizes normal power supply of filter white unit, but also can complete normal filter white work under power failure abnormal condition, to a certain extent, improve the abnormal handling capability of system.

Description

Technical Field

[0001] This invention belongs to the field of blood filtration and heat sealing technology, and more specifically, relates to a multi-process coordinated scheduling integrated blood preparation production line system for filtration and heat sealing. Background Technology

[0002] Filtering out leukocytes from blood products is a crucial method for reducing adverse transfusion reactions in clinical patients. Leukocytes in blood products easily lead to febrile nonhemolytic transfusion reactions (FNHTR), the leading cause of adverse transfusion reactions, accounting for approximately 52.1% of all such reactions. Leukocyte filtration (hereinafter referred to as "leukocyte filtration") can remove 99.9% of leukocytes from the blood, effectively preventing FNHTR. Leukocyte filtration is a vital step in blood preparation within the blood collection and supply industry. While current leukocyte filtration equipment can monitor the entire process, operation remains largely manual, involving tasks such as bag hanging, barcode scanning, stopper breaking, and heat sealing. Therefore, solving the problem of automated and efficient leukocyte filtration blood preparation is crucial for improving standardized operating procedures and preparation efficiency, as well as further enhancing transfusion safety and therapeutic efficacy.

[0003] To address the aforementioned technical problems, Chinese Utility Model Patent CN208864907U discloses a fully automatic blood filtration device. 1. This utility model employs the key technology of "fully automatic" and provides a new device for a "fully automatic blood filtration device." 2. This utility model includes a container for the filtered blood bag, thus achieving the beneficial effect of accommodating the filtered blood bag. 3. This utility model includes a push actuator and a push plate, thus achieving the beneficial effect of intermittently squeezing the filtered blood bag and successively expelling the gas from the filtered blood bag. 4. The push actuator of this utility model can be either a pneumatic cylinder push actuator structure or an electric pneumatic cylinder push actuator structure, thus achieving the beneficial effects of allowing selection of the push actuator structure according to specific circumstances, broadening manufacturing options, facilitating manufacturing, and enhancing implementation efficiency and actual results. 5. This utility model includes a pre-filtration blood bag, a pre-filtration tubing, a filter tubing, a tubing clamp, an exhaust tubing, an exhaust tubing clamp, a post-filtration tubing, and a post-filtration blood bag. It also allows for electrical connections between the circuit board and the weighing device, tubing clamp, exhaust tubing clamp, push actuator, all-in-one computer, and the weighing device and display screen. This provides essential conditions for the automatic removal of gas from the post-filtration blood bag. Specifically, the push plate of the push actuator compresses the post-filtration blood bag, causing the gas in the post-filtration blood bag to be discharged into the pre-filtration blood bag through the post-filtration tubing, exhaust tubing, and pre-filtration tubing. This fundamentally solves the problem of gas removal from the post-filtration blood bag in the filtration apparatus. 6. This utility model achieves fully automatic, unattended operation, real-time, full-process automatic monitoring, and accurate automatic information recording. It effectively reduces operator workload and significantly lowers the labor intensity of staff.

[0004] The above-mentioned patented technologies have to some extent pushed the preparation of bleached blood products toward automation and standardization, but there are still the following technical problems and areas for improvement: (1) The above-mentioned technologies only take automated measures for the bleaching process, but do not systematically integrate the subsequent blood braiding heat sealing process. Therefore, from the perspective of automating the entire process of bleached blood preparation, the solution can still be further optimized and improved; (2) The above-mentioned solutions can only be applied to the bleaching preparation of a single blood product, and it is difficult to meet the increasingly high preparation workload. Therefore, the blood bleaching equipment can be improved from the perspective of mass production; (3) In response to the improvement direction proposed in (2), the equipment should have the ability to identify and sort abnormalities such as blood blockage and breakage during the bleaching process. Summary of the Invention

[0005] To address the aforementioned deficiencies or improvement needs of existing technologies, this invention provides a multi-process collaborative scheduling integrated blood preparation production line system for bleaching and heat sealing. By setting up a manual bag-hanging area, a bleaching preparation area, a heat sealing and transfer area, and a fault handling area, and interconnecting these areas via a track, mobile bleaching units are placed on the track and move autonomously to the heat sealing and transfer or fault handling area according to their bleaching completion status. The mobile bleaching units communicate and coordinate with each other to achieve single-track sharing. This not only integrates blood bleaching, heat sealing, and bleaching anomaly identification and sorting operations, but also greatly improves the ability to handle large-scale preparation tasks and increases the production efficiency of bleached blood products. Furthermore, this invention integrates a mobile power supply within each mobile bleaching unit, which can automatically find a charging connector for charging. This not only ensures normal power supply to the bleaching unit but also allows it to complete normal bleaching operations under abnormal power outage conditions, thus improving the system's anomaly handling capabilities to a certain extent.

[0006] To achieve the above objectives, a multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and separation includes: The production line infrastructure includes a manual bag-hanging area serving as the front-end operation window; a filter preparation area located behind the manual bag-hanging area, forming the main body of the production line; a heat-sealing and transfer area and a fault handling area located behind the filter preparation area; and an interconnected scheduling track connecting the manual bag-hanging area, the filter preparation area, the heat-sealing and transfer area, and the fault handling area. The manual bag-hanging area has a bag-hanging stop station; the filter preparation area has a filter-sealing stop station; the heat-sealing and transfer area has a heat-sealing station; and the fault handling area has a faulty bag transfer station. The mobile filter unit based on the interconnected scheduling track includes a track guide walking component, a transfer bag placement and output component located above the track guide walking component, a vertical support rod located above the transfer bag placement and output component, a bag hanging and weighing component arranged from top to bottom along the vertical support rod, a plug breaker and filter clamping component, and a main controller for controlling the execution of functions. The heat sealing output unit, which is fixedly installed at the heat sealing station, includes a positioning base, a transfer output component located above the positioning base for carrying blood products away from the output heat sealing transmission area, a gripping heat sealing component located above the transfer output component for gripping and heat sealing blood catheters, and a forward push drive component located on the back side of the gripping heat sealing component; the forward push drive component is used to push the gripping heat sealing component closer to the approaching mobile filter unit; the gripping heat sealing component includes a vertical connecting block connected to the output end of the forward push drive component, and four sets of circumferential gripping components and heat sealing components for gripping and locking blood catheters fixed to the front side of the vertical connecting block and arranged vertically evenly.

[0007] Preferably, the track-guided walking assembly includes: The chassis consists of a first base block, a tracked wheel located below the first base block and in contact with the ground, a rail guide anti-detachment block located below the first base block and slidably connected to the interconnected scheduling track, a rear charging interface and a mobile power supply located on the side of the first base block, and a charging connector located on the back side of the filter white parking station; the charging connector and the rear charging interface are plugged into each other to achieve charging.

[0008] Preferably, the movable whitening filter unit further includes: An orientation adjustment component is provided between the track guide walking component and the transfer bag placement output component. It includes a rotary drive motor fixed in the first base block and a rotating shaft fixedly connected to the rotary drive motor on the same axis. The top end of the rotating shaft is fixedly connected to the transfer bag placement output component.

[0009] Preferably, the transfer bag placement output component includes: The system includes a second base block fixedly connected to the upper end of the rotating shaft, a horizontal slide rail disposed within the second base block, a first push rod horizontally fixedly disposed on the left side plate of the second base block, a horizontal sliding block slidably connected to the horizontal slide rail, and a transfer bag tray fixed to the upper end of the horizontal sliding block. The transfer bag tray is fixedly connected to the end of the first push rod.

[0010] Preferably, the filter clamping assembly includes: The elastic clamping assembly, the pipe straightening assembly disposed inside the vertical support rod to adjust the height of the elastic clamping assembly, and the intermediate connecting rod serving as the connecting member between the elastic clamping assembly and the pipe straightening assembly; The elastic clamping assembly includes an outer shell, a filter clamping area located in the middle of the outer shell and open on the front, top, and bottom sides, side cavities on the left and right sides of the outer shell, a rotating connection hole in the partition wall between the filter clamping area and the side cavity, an intermediate connecting block rotatably connected to the rotating connection hole, a filter clamping block and a stop block respectively fixedly connected to the inner and outer ends of the intermediate connecting block, and a pop-out spring between the stop block and the side wall of the side cavity; the filter clamping block and the stop block are located in the filter clamping area and the side cavity respectively. The pipeline straightening assembly includes a drive motor fixedly connected to a vertical support rod, a bevel gear set connected to the output shaft of the drive motor, a vertical lead screw fixedly connected to the output gear of the bevel gear set on the same axis, and a height adjustment nut block that maintains linear transmission with the vertical lead screw; the height adjustment nut block is fixedly connected to the left end of the intermediate connecting rod. The intermediate connecting rod is provided with a stress sensing part in the middle.

[0011] Preferably, the movable whitening filter unit further includes: An on / off controlled peristaltic pump is located below the plug opener; During the bleaching process, the on / off control peristaltic pump is controlled to release the clamping state of the blood tubing to achieve blood bleaching; after bleaching is completed, the on / off control peristaltic pump is controlled to clamp the blood tubing and pump the air in the transfer bag back into the upper blood bag.

[0012] Preferably, the transmission output component includes: A conveyor belt, positioned above the positioning base and below the lower surface of the transfer bag tray, is used to transport and output the filtered blood product. A baffle assembly, located on the front side of the conveyor belt, is used to cooperate with the transfer bag placement and output assembly to move the transfer bag onto the conveyor belt. The material blocking assembly includes a side support plate, a second push rod that is flush with the height of the transfer bag above the transfer bag tray and fixedly connected to the side support plate, and a stop block disposed at the front end of the second push rod; By controlling the extension of the first push rod, the transfer bag tray and the transfer bag above it are pushed to the top of the conveyor belt. Then, the second push rod is controlled to extend, and the stop block is pushed to the rear of the transfer bag above the transfer bag tray. Subsequently, the first push rod is controlled to retract, so that the transfer bag is blocked by the stop block and falls onto the conveyor belt.

[0013] Preferably, the forward drive component includes: The system includes a support rod fixedly connected to the positioning base, a push-drive motor fixedly connected to the top of the support rod, a push-drive screw fixedly connected to the output end of the push-drive motor in a vertical direction, a push-drive slider that maintains linear transmission with the push-drive screw, and a cross link rotatably connected to the push-drive slider at one end for generating horizontal push; the gripping heat sealing assembly is located at the front end of the cross link.

[0014] Preferably, the wraparound gripping component includes: The system comprises: a pipe guide plate fixedly connected to the vertical connecting block; a third push rod fixedly connected laterally to the right end of the pipe guide plate; an arc-shaped moving block located at the front end of the third push rod; an encircling drive motor symmetrically arranged on the upper and lower sides of the arc-shaped moving block; an encircling drive gear fixedly connected coaxially to the output shaft of the encircling drive motor; an arc-shaped encircling claw rotating concentrically with the arc-shaped moving block; arc-shaped teeth located on the outer wall of the arc-shaped encircling claw and meshing with the encircling drive gear; an arc-shaped guide groove opened inside the arc-shaped encircling claw; and a limiting slider fixedly connected to the arc-shaped moving block and slidably connected to the arc-shaped guide groove. The pipe guide base plate includes a funnel-shaped guide opening and a pipe insertion slot connected to the convergence point of the funnel-shaped guide opening; Pipe position sensors are installed on both sides of the pipe insertion slot to sense the arrival status of the pipe.

[0015] Preferably, the heat-sealing component includes: A clamping drive motor is fixedly connected to the pipe guide plate perpendicular to the pipe insertion groove direction; a reverse lead screw is fixedly connected to the clamping drive motor on the same axis; a set of clamping drive sliders is connected to the reverse lead screw in a reverse linear transmission; a heat sealing clamping head is fixedly connected to the clamping drive sliders; and a heating part is provided on the side directly opposite to the heat sealing clamping head. A slightly convex cutting blade is horizontally positioned on the side of the heating section of the uppermost heat-sealing assembly.

[0016] In summary, compared with the prior art, the above-described technical solutions conceived by this invention can achieve the following beneficial effects: 1. This invention discloses a multi-process collaborative scheduling integrated blood filtration and heat sealing production line system. By setting up a manual bag-hanging area, a filtration preparation area, a heat sealing and transfer area, and a fault handling area, and interconnecting these areas via a track, mobile filtration units are placed on the track and move autonomously to the heat sealing and transfer or fault handling area according to their filtration completion status. The mobile filtration units communicate and coordinate with each other to achieve single-track sharing. This not only integrates blood filtration, heat sealing, and filtration anomaly identification and sorting operations, but also greatly improves the ability to handle large-scale preparation tasks and increases the production efficiency of filtration-filtered blood products. Furthermore, this invention integrates a mobile power supply within each mobile filtration unit, which can automatically find a charging connector for charging. This not only ensures normal power supply to the filtration unit but also allows normal filtration to continue under abnormal power outage conditions, thus improving the system's anomaly handling capability to a certain extent.

[0017] 2. The present invention provides a multi-process coordinated scheduling integrated blood preparation production line system for filtration and heat sealing. By employing a screw and nut assembly to achieve height lifting of the elastic clamping assembly, and by sensing the dragging mass through a stress sensing unit, the system can identify the straightening state of the blood tubing, thereby avoiding shaking and tangling of the tubing in a non-straightened state. In addition, the transfer bag below the blood tubing can be pulled to an upward tilted state, thereby ensuring that the air inside the transfer bag is located at the tube opening. The air inside the bag is then reversed and drawn back by an on / off controlled peristaltic pump 280, thereby eliminating residual gas inside the transfer bag. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of a multi-process coordinated scheduling integrated blood preparation production line system for filtration and heat sealing, according to an embodiment of the present invention. Figure 2 This is an enlarged view of the bag hanging station of a multi-process coordinated scheduling integrated blood preparation production line system for filtration and heat sealing, according to an embodiment of the present invention. Figure 3 This is an overall structural diagram of the mobile filtration unit of a multi-process collaborative scheduling integrated filtration and heat sealing blood preparation production line system according to an embodiment of the present invention; Figure 4 This is a diagram showing the internal structure of the filter clamping assembly of a multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and purification, according to an embodiment of the present invention. Figure 5 A partial enlarged view A is of a multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment and synthesis according to an embodiment of the present invention; Figure 6 This is a diagram showing the coordinated state of the mobile filtration unit and the heat-sealing output unit in a multi-process coordinated scheduling integrated blood preparation production line system for filtration and heat sealing according to an embodiment of the present invention. Figure 7This is a schematic diagram of the overall structure of the heat-sealing output unit of a multi-process collaborative scheduling integrated blood preparation production line system for filtration and heat sealing, according to an embodiment of the present invention. Figure 8 This is a schematic diagram of the internal structure of the ring-shaped gripping component of a multi-process collaborative scheduling integrated blood preparation production line system for filtration, heat treatment, and separation, according to an embodiment of the present invention. Figure 9 This is a schematic diagram of the internal structure of the heat-sealing component of a multi-process collaborative scheduling integrated blood preparation production line system for filtration and heat sealing, according to an embodiment of the present invention. Figure 10 This is a schematic diagram of the micro-convex cutting blade position structure of a multi-process collaborative scheduling integrated blood preparation production line system for filtration and heat sealing according to an embodiment of the present invention; In all the accompanying drawings, the same reference numerals denote the same technical features, specifically: 1-Production line foundation, 110-Manual bag hanging area, 111-Bag hanging docking station, 120-Filter preparation area, 121-Filter docking station, 130-Heat sealing and transfer area, 131-Heat sealing station, 140-Fault handling area, 141-Fault bag transfer station, 150-Interconnected scheduling track, 2-Mobile filter unit, 210-Rail guide walking assembly, 211-First base block, 212-Crawler walking wheel, 213-Rail guide anti-detachment block, 214-Tail charging interface, 2140-Charging connector, 220-Orientation adjustment assembly, 221-Rotary drive motor, 22 2-Rotating shaft, 230-Transfer bag placement and output assembly, 231-Second base block, 232-Horizontal slide rail, 233-First push rod, 234-Transfer bag tray, 235-Horizontal sliding block, 240-Vertical support rod, 250-Filter clamping assembly, 251-Elastic clamping assembly, 2510-Outer shell, 2511-Filter clamping area, 2512-Side cavity, 2513-Ejection spring, 2514-Rotating connection hole, 2515-Intermediate connecting block, 2516-Filter clamping block, 252-Intermediate connecting rod, 253-Pipe straightening assembly, 2531-Drive motor, 2532-Bevel gear set, 2533-Vertical lead screw, 2534 - Adjusting nut block, 260- Bag hanging weighing assembly, 270- Cork breaker, 280- Opening and closing controlled peristaltic pump, 3- Heat sealing output unit, 300- Positioning base, 301- Output temporary storage section, 310- Transfer output assembly, 311- Conveyor belt, 312- Material blocking assembly, 3121- Side support plate, 3122- Second push rod, 3123- Stop block, 320- Forward push drive assembly, 321- Support upright, 322- Forward push drive motor, 323- Forward push drive screw, 324- Forward push drive slider, 325- Cross linkage, 330- Gripping heat sealing assembly, 331- Ring gripping assembly, 3311- Pipe position guide plate, 33111 - Bucket-shaped guide port, 33112 Pipe insertion slot, 3312 Third push rod, 3313 Arc-shaped moving block, 3314 Encircling drive motor, 3315 Encircling drive gear, 3316 Limiting slider, 3317 Arc-shaped encircling claw, 3318 Arc-shaped guide groove, 3319 Pipe position sensor, 332 Heat sealing assembly, 3321 Clamping drive motor, 3322 Reverse lead screw, 3323 Clamping drive slider, 3324 Heat sealing clamping head, 3325 Heating part, 3326 Micro-convex cutting blade, 333 Vertical connecting block, 401 Blood bag, 402 Transfusion tubing, 403 Leukocyte filter, 404 Transfer belt. Detailed Implementation

[0019] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the present invention.

[0020] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0021] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0022] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the invention. Furthermore, the technical features involved in the various embodiments of this invention described below can be combined with each other as long as they do not conflict with each other.

[0023] like Figures 1-10 As shown, in this embodiment of the invention, the multi-process collaborative scheduling integrated blood preparation production line system for filtration and heat treatment includes: Production line base 1 includes a manual bag-hanging area 110 serving as a front-end operation window, a filter preparation area 120 located behind the manual bag-hanging area 110 serving as the main body of the production line, a heat-sealing transfer area 130 and a fault handling area 140 located behind the filter preparation area 120, and an interconnected scheduling track 150 connecting the manual bag-hanging area 110, the filter preparation area 120, the heat-sealing transfer area 130, and the fault handling area 140; the manual bag-hanging area 110 has a bag-hanging docking station 111, the filter preparation area 120 has a filter-sealing docking station 121, the heat-sealing transfer area 130 has a heat-sealing station 131, and the fault handling area 140 has a fault bag transfer station 141. The mobile filter unit 2, which travels based on the interconnected scheduling track 150, includes a track guide walking component 210, a transfer bag placement and output component 230 located above the track guide walking component 210, a vertical support rod 240 located above the transfer bag placement and output component 230, a hanging bag weighing component 260 arranged from top to bottom along the vertical support rod 240, a plug breaker 270 and a filter clamping component 250, and a main controller for controlling the execution of functions. The heat sealing output unit 3, which is fixedly installed at the heat sealing station 131, includes a positioning base 300, a transfer output component 310 disposed above the positioning base 300 for carrying blood products away from the output heat sealing transmission area 130, a gripping heat sealing component 330 disposed above the transfer output component 310 for gripping and heat sealing blood catheters, and a forward push drive component 320 disposed on the back side of the gripping heat sealing component 330; the forward push drive component 320 is used to push the gripping heat sealing component 330 closer to the approaching mobile filter unit 2; the gripping heat sealing component 330 includes a vertical connecting block 333 connected to the output end of the forward push drive component 320, and four sets of circumferential gripping components 331 and heat sealing components 332 fixed to the front side of the vertical connecting block 333 and arranged vertically evenly.

[0024] like Figure 5 As shown, in this embodiment of the invention, the track-guided walking assembly 210 includes: The chassis consists of a first base block 211, a tracked wheel 212 located below the first base block 211 and in contact with the ground, a rail guide anti-detachment block 213 located below the first base block 211 and slidably connected to the interconnected scheduling track 150, a rear charging interface 214 and a mobile power supply located on the side of the first base block 211, and a charging connector 2140 located on the back side of the filter white parking station 121; the charging connector 2140 and the rear charging interface 214 are plugged into each other to achieve charging.

[0025] In this embodiment of the invention, by setting up a manual bag hanging area, a bleaching preparation area, a heat sealing and transfer area, and a fault handling area, and by interconnecting multiple areas with the help of a track, the mobile bleaching unit is placed in the track and moves to the heat sealing and transfer or fault handling area according to the completion status of bleaching. The mobile bleaching units communicate with each other and coordinate to achieve single track sharing. This not only realizes the integrated operation of blood bleaching, heat sealing, and bleaching abnormality identification and sorting, but also greatly improves the ability to cope with a large number of preparation tasks and improves the production efficiency of bleached blood products.

[0026] Furthermore, this invention integrates a mobile power supply within the mobile whitening unit, which can automatically locate the charging connector for charging. This not only ensures normal power supply to the whitening unit but also enables normal whitening operations during power outages, thereby improving the system's ability to handle abnormal situations to a certain extent.

[0027] like Figure 3 As shown, in this embodiment of the invention, the movable whitening filter unit 2 further includes: An orientation adjustment component 220 is provided between the track guide walking component 210 and the transfer bag placement output component 230. It includes a rotary drive motor 221 fixed in the first base block 211 and a rotating shaft 222 coaxially fixedly connected to the rotary drive motor 221. The top end of the rotating shaft 222 is fixedly connected to the transfer bag placement output component 230.

[0028] like Figure 3 and 5 As shown, in this embodiment of the invention, the transfer bag placement and output assembly 230 includes: The second base block 231 is fixedly connected to the upper end of the rotating shaft 222, a horizontal slide rail 232 is disposed in the second base block 231, a first push rod 233 is horizontally fixedly disposed on the left side plate of the second base block 231, a horizontal sliding block 235 is slidably connected to the horizontal slide rail 232, and a transfer bag tray 234 is fixed to the upper end of the horizontal sliding block 235. The transfer bag tray 234 is fixedly connected to the end of the first push rod 233.

[0029] like Figure 4 As shown, in this embodiment of the invention, the filter clamping assembly 250 includes: The elastic clamping assembly 251, the pipe straightening assembly 253 disposed inside the vertical support rod 240 to adjust the height position of the elastic clamping assembly 251, and the intermediate connecting rod 252 serving as the connecting member between the elastic clamping assembly 251 and the pipe straightening assembly 253. The elastic clamping assembly 251 includes a housing 2510, a filter clamping area 2511 located in the middle of the housing 2510 and open on the front, top, and bottom sides, side cavities 25122 located on the left and right sides of the housing 2510, a rotating connection hole 2514 located in the partition wall between the filter clamping area 2511 and the side cavity 25122, an intermediate connecting block 2515 rotatably connected to the rotating connection hole 2514, filter clamping blocks 2516 and a stop block fixedly connected to the inner and outer ends of the intermediate connecting block 2515 respectively, and a pop-out spring 2513 located between the stop block and the side wall of the side cavity 2512; the filter clamping blocks 2516 and the stop blocks are located in the filter clamping area 2511 and the side cavity 2512 respectively. The pipeline straightening assembly 253 includes a drive motor 2531 fixedly connected to the vertical support rod 240, a bevel gear set 2532 connected to the output shaft of the drive motor 2531, a vertical lead screw 2533 fixedly connected to the output gear of the bevel gear set 2532 on the same axis, and a height adjustment nut block 2534 that maintains linear transmission with the vertical lead screw 2533; the height adjustment nut block 2534 is fixedly connected to the left end of the intermediate connecting rod 252. The intermediate connecting rod is provided with a stress sensing part in the middle.

[0030] like Figure 3 As shown, in this embodiment of the invention, the movable whitening filter unit 2 further includes: An on / off controlled peristaltic pump 280 is located below the plugger 270; During the bleaching process, the on / off control peristaltic pump 280 is controlled to release the clamping state of the blood tubing to achieve blood bleaching; after the bleaching is completed, the on / off control peristaltic pump 280 is controlled to clamp the blood tubing and pump the air in the transfer bag back into the upper blood bag.

[0031] In this embodiment of the invention, the height of the elastic clamping assembly 251 is raised by using a screw and nut assembly, and the dragging mass can be sensed by the stress sensing unit to realize the straightening state of the blood tubing, thereby avoiding shaking and tangling of the tubing in the non-straightened state; in addition, the transfer bag below the blood tubing can be pulled to an upward tilted state, thereby ensuring that the air in the transfer bag is located at the tube opening, and the air in the bag is reversed by using the opening and closing controlled peristaltic pump 280, thereby eliminating the gas residue in the transfer bag.

[0032] like Figure 7 As shown, in this embodiment of the invention, the transmission output component 310 includes: A conveyor belt 311, located below the lower surface of the transfer bag tray 234 and above the positioning base 300, is used to transport and output the filtered blood product. A baffle assembly 312, located on the front side of the conveyor belt 311, is used to cooperate with the transfer bag placement and output assembly 230 to transfer the transfer bag to the conveyor belt 311. The material blocking assembly 312 includes a side support plate 3121, a second push rod 3122 that is flush with the height of the transfer bag above the transfer bag tray 234 and fixedly connected to the side support plate 3121, and a stop block 3123 provided at the front end of the second push rod 3122. By controlling the first push rod 233 to extend, the transfer bag tray 234 and the transfer bag above it are pushed to the top of the conveyor belt 311. Then, the second push rod 3122 is controlled to extend, and the stop block 3123 is pushed to the rear of the transfer bag above the transfer bag tray 234. Then, the first push rod 233 is controlled to retract, so that the transfer bag is blocked by the stop block 3123 and falls onto the conveyor belt 311.

[0033] like Figure 7 As shown, in this embodiment of the invention, the forward-pushing drive component 320 includes: The system includes a support rod 321 fixedly connected to the positioning base 300, a push drive motor 322 fixedly connected to the top of the support rod 321, a push drive screw 323 fixedly connected to the output end of the push drive motor 322 in a vertical direction, a push drive slider 324 that maintains linear transmission with the push drive screw 323, and a cross link 325 rotatably connected to the push drive slider 324 at one end for generating horizontal push; the gripping heat sealing assembly 330 is located at the front end of the cross link 325.

[0034] like Figure 7 and Figure 8 As shown, in this embodiment of the invention, the wraparound gripping component 331 includes: The system comprises: a pipe guide plate 3311 fixedly connected to the vertical connecting block 333; a third push rod 3312 fixedly connected laterally to the right end of the pipe guide plate 3311; an arc-shaped moving block 3313 located at the front end of the third push rod 3312; a ring drive motor 3314 symmetrically arranged on the upper and lower sides of the arc-shaped moving block 3313; a ring drive gear 3315 fixedly connected coaxially to the output shaft of the ring drive motor 3314; an arc-shaped ring claw 3317 rotating concentrically with the arc-shaped moving block 3313; an arc-shaped tooth located on the outer wall of the arc-shaped ring claw 3317 and meshing with the ring drive gear 3315; an arc-shaped guide groove 3318 formed inside the arc-shaped ring claw 3317; and a limiting slider 3316 fixedly connected to the arc-shaped moving block 3313 and slidably connected to the arc-shaped guide groove 3318. The pipe guide base plate 3311 includes a funnel-shaped guide opening 33111 and a pipe insertion groove 33112 that is connected to the convergence point of the funnel-shaped guide opening 33111. Pipe position sensors 3319 are installed on both sides of the pipe insertion slot 33112 to sense the arrival status of the pipe.

[0035] like Figure 9 As shown, in this embodiment of the invention, the heat-sealing component 332 includes: A clamping drive motor 3321 is fixedly connected to the pipe guide plate 3311 in a direction perpendicular to the pipe insertion groove 33112; a reverse lead screw 3322 is fixedly connected to the clamping drive motor 3321 in a coaxial manner; a set of clamping drive sliders 3323 are connected to the reverse lead screw 3322 in a reverse linear transmission; a heat sealing clamping head 3324 is fixedly connected to the clamping drive slider 3323; and a heating part 3325 is provided on one side of the heat sealing clamping head 3324 in the direction directly opposite to the heat sealing clamping head 3324. A slightly convex cutting blade 3326 is arranged on the side of the heating part 3325 of the uppermost heat sealing assembly 332.

[0036] In addition to the above embodiments, it should be noted that: (1) the number of manual bag hanging area 110, whitening preparation area 120, heat sealing and transfer area 130 and fault handling area 140 can be increased or decreased according to the actual workload requirements; (2) a barcode scanning device for reading mother bag information can be set in the blood hanging area, and an RFID radio frequency barcode reading device for reading transfer bag information can be set at the bottom of the transfer bag tray to identify and check the consistency of the barcode information of the mother bag and the transfer bag.

[0037] The working principle of this invention is as follows: First, in the initial state, all mobile leukocyte filtration units 2 without blood bags line up to enter the manual bag hanging area 110. Then, the operator hoists the mother bag onto the bag hanging weighing component 260, inserts the easy-break stopper into the stopper breaker 270, inserts the leukocyte filter between the filter clamping blocks 2516, and inserts the tubing into the on / off controlled peristaltic pump 280. Next, the bag hanging weighing component 260 senses the weight signal of the mother bag and starts timing. The mobile leukocyte filtration unit 2, after the leukocyte filtration product is installed, then... The mobile filtration unit 2 will move into the idle filtration docking station 121 and enter the filtration process waiting state. Then, it will determine whether filtration is complete by sensing the quality of the mother bag. If the filtration time exceeds the normal range, it is considered an abnormality, and the mobile filtration unit 2 will carry the abnormally filtration blood product to the faulty bag transfer station 141 for manual handling. Conversely, if the filtration completion time is within the normal range, the mobile filtration unit 2 will carry the filtration completed blood product into the heat sealing transfer station. The heat sealing unit 3 at heat sealing station 131 docks with the heat sealing output unit 3 in zone 130. This docking process begins by controlling the forward drive motor 322 to rotate, thus pushing the gripping heat sealing component 330 forward. The gripping component 331 then encircles and positions the blood tubing below the filter disc. Once all four tube position sensors 3319 detect the tubing is engaged, heat sealing is performed using the heat sealing component 332. Under the action of the micro-convex cutting blade 3326 in the uppermost heating section 3325, the blood... The braid is clamped at the heat-sealing point, completing the heat-sealing operation. Immediately afterwards, the forward drive motor 322 is controlled to rotate in the reverse direction, pulling the braid back to directly above the conveyor belt 311. The first push rod 233 is then pushed out, and under the action of the material blocking component 312, the transfer bag is blocked and falls onto the conveyor belt 311. Finally, the gripping heat-sealing component 330 is controlled to release the braid, allowing it to fall freely onto the conveyor belt 311. The conveyor belt 311 is then started, outputting the braid and transfer bag together. The above operation is repeated to complete the multi-task collaborative work.

[0038] The above are merely preferred embodiments of this application and are not intended to limit this application. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the protection scope of this application. The above are merely preferred embodiments of this application. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of this application, and these improvements and modifications should also be considered within the protection scope of this application.

Claims

1. A multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and synthesis, characterized in that, include: The production line base (1) includes a manual bag-hanging area (110) serving as a front-end operation window, a filter preparation area (120) located behind the manual bag-hanging area (110) serving as the main body of the production line, a heat-sealing transfer area (130) and a fault handling area (140) located behind the filter preparation area (120), and an interconnected scheduling track (150) connecting the manual bag-hanging area (110), the filter preparation area (120), the heat-sealing transfer area (130), and the fault handling area (140). The manual bag-hanging area (110) is equipped with a bag-hanging docking station (111), the filter preparation area (120) is equipped with a filter-sealing docking station (121), the heat-sealing transfer area (130) is equipped with a heat-sealing station (131), and the fault handling area (140) is equipped with a faulty bag transfer station (141). The mobile filter unit (2) based on the interconnected scheduling track (150) includes a track guide walking component (210), a transfer bag placement output component (230) located above the track guide walking component (210), a vertical support rod (240) located above the transfer bag placement output component (230), a hanging bag weighing component (260) arranged from top to bottom along the vertical support rod (240), a plug breaker (270) and a filter clamping component (250), and a main controller for controlling the execution of functions; The heat sealing output unit (3) is fixedly installed at the heat sealing station (131), which includes a positioning base (300), a transfer output component (310) disposed above the positioning base (300) for carrying blood products away from and outputting them to the heat sealing transfer area (130), a gripping heat sealing component (330) disposed above the transfer output component (310) for gripping and heat sealing blood catheters, and a forward push drive component (320) disposed on the back side of the gripping heat sealing component (330); the forward push drive component (320) is used to push the gripping heat sealing component (330) closer to the approaching mobile filter unit (2); the gripping heat sealing component (330) includes a vertical connecting block (333) connected to the output end of the forward push drive component (320), and four sets of gripping and locking blood catheters, which are fixed to the front side of the vertical connecting block (333) and arranged vertically and evenly, and a heat sealing component (332).

2. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and synthesis according to claim 1, characterized in that, The track-guided walking assembly (210) includes: The chassis consists of a first base block (211), a tracked wheel (212) located below the first base block (211) and in contact with the ground, a rail guide anti-detachment block (213) located below the first base block (211) and slidably connected to the interconnected scheduling track (150), a rear charging interface (214) located on the side of the first base block (211) and a mobile power supply, and a charging connector (2140) located on the back side of the filter white parking station (121); the charging connector (2140) and the rear charging interface (214) are plugged into each other to achieve charging.

3. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and synthesis according to claim 2, characterized in that, The movable whitening filter unit (2) also includes: An orientation adjustment component (220) is provided between the track guide walking component (210) and the transfer bag placement output component (230). It includes a rotary drive motor (221) fixed in the first base block (211) and a rotating shaft (222) coaxially fixedly connected to the rotary drive motor (221). The top end of the rotating shaft (222) is fixedly connected to the transfer bag placement output component (230).

4. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and synthesis according to claim 3, characterized in that, The transfer bag placement output assembly (230) includes: The second base block (231) is fixedly connected to the upper end of the rotating shaft (222), the horizontal slide rail (232) is provided in the second base block (231), the first push rod (233) is horizontally fixedly provided on the left side plate of the second base block (231), the horizontal sliding block (235) is slidably connected to the horizontal slide rail (232), and the transfer bag tray (234) is fixed to the upper end of the horizontal sliding block (235). The transfer bag tray (234) is fixedly connected to the end of the first push rod (233).

5. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and synthesis according to claim 1, characterized in that, The filter clamping assembly (250) includes: The elastic clamping assembly (251), the pipe straightening assembly (253) disposed inside the vertical support rod (240) to adjust the height position of the elastic clamping assembly (251), and the intermediate connecting rod (252) serving as the connecting member between the elastic clamping assembly (251) and the pipe straightening assembly (253). The elastic clamping assembly (251) includes an outer shell (2510), a filter clamping area (2511) located in the middle of the outer shell (2510) and open on the front, top, and bottom sides, side cavities (2512) located on the left and right sides of the outer shell (2510), a rotating connection hole (2514) located in the partition wall between the filter clamping area (2511) and the side cavity (2512), an intermediate connecting block (2515) rotatably connected to the rotating connection hole (2514), a filter clamping block (2516) and a stop block respectively fixedly connected to the inner and outer ends of the intermediate connecting block (2515), and a pop-out spring (2513) located between the stop block and the side wall of the side cavity (2512); the filter clamping block (2516) and the stop block are located in the filter clamping area (2511) and the side cavity (2512) respectively. The pipeline straightening assembly (253) includes a drive motor (2531) fixedly connected to a vertical support rod (240), a bevel gear set (2532) connected to the output shaft of the drive motor (2531), a vertical lead screw (2533) fixedly connected to the output gear of the bevel gear set (2532) on the same axis, and a height adjustment nut block (2534) that maintains linear transmission with the vertical lead screw (2533); the height adjustment nut block (2534) is fixedly connected to the left end of the intermediate connecting rod (252); The intermediate connecting rod is provided with a stress sensing part in the middle.

6. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and separation according to claim 5, characterized in that, The movable whitening filter unit (2) also includes: An on / off controlled peristaltic pump (280) is located below the plug opener (270). During the bleaching process, the on / off control peristaltic pump (280) is controlled to release the clamping state of the blood tubing to achieve blood bleaching; after the bleaching is completed, the on / off control peristaltic pump (280) is controlled to clamp the blood tubing and pump the air in the transfer bag back into the upper blood bag.

7. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and synthesis according to claim 4, characterized in that, The transmission output component (310) includes: A conveyor belt (311) is disposed above the positioning base (300) below the lower surface of the transfer bag tray (234) for transporting and outputting the filtered blood product, and a baffle assembly (312) is disposed on the front side of the conveyor belt (311) for cooperating with the transfer bag placement and output assembly (230) to transfer the transfer bag to the conveyor belt (311). The material blocking assembly (312) includes a side support plate (3121), a second push rod (3122) that is flush with the height of the transfer bag above the transfer bag tray (234) and fixedly connected to the side support plate (3121), and a stop block (3123) located at the front end of the second push rod (3122). By controlling the first push rod (233) to extend, the transfer bag tray (234) and the transfer bag above it are pushed to the top of the conveyor belt (311). Then, the second push rod (3122) is controlled to extend, and the stop block (3123) is pushed to the rear of the transfer bag above the transfer bag tray (234). Then, the first push rod (233) is controlled to retract, so that the transfer bag is blocked by the stop block (3123) and falls onto the conveyor belt (311).

8. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and separation according to claim 7, characterized in that, The forward drive component (320) includes: The support rod (321) is fixedly connected to the positioning base (300), the push drive motor (322) is fixedly connected to the top of the support rod (321), the push drive screw (323) is fixedly connected to the output end of the push drive motor (322) in a vertical direction, the push drive slider (324) maintains linear transmission with the push drive screw (323), and the cross link (325) is rotatably connected to the push drive slider (324) and used to generate horizontal push; the gripping heat sealing component (330) is located at the front end of the cross link (325).

9. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and separation according to claim 8, characterized in that, The wraparound gripping component (331) includes: The pipe guide plate (3311) is fixedly connected to the vertical connecting block (333), the third push rod (3312) is fixedly connected to the right end of the pipe guide plate (3311) in the lateral direction, the arc-shaped moving block (3313) is provided at the front end of the third push rod (3312), the encircling drive motor (3314) is symmetrically arranged on the left and right sides of the arc-shaped moving block (3313), and the encircling drive motor (3314) is fixedly connected to the output shaft of the encircling drive motor (3314) in the axial direction. The gear (3315), the arc-shaped circumferential claw (3317) that rotates concentrically with the arc-shaped moving block (3313), the arc-shaped teeth provided on the outer wall of the arc-shaped circumferential claw (3317) and meshing with the circumferential drive gear (3315), the arc-shaped guide groove (3318) opened inside the arc-shaped circumferential claw (3317), and the limiting slider (3316) that is fixedly connected to the arc-shaped moving block (3313) and slidably connected to the arc-shaped guide groove (3318). The pipe guide base plate (3311) includes a bucket-shaped guide opening (33111) and a pipe insertion slot (33112) connected to the convergence point of the bucket-shaped guide opening (33111). Pipe position sensors (3319) are installed on both sides of the pipe insertion slot (33112) to sense the arrival status of the pipe.

10. The multi-process coordinated scheduling integrated blood preparation production line system for filtration, heat treatment, and synthesis according to claim 9, characterized in that, The heat-sealing component (332) includes: A clamping drive motor (3321) is fixedly connected to the pipe guide plate (3311) in a direction perpendicular to the pipe insertion groove (33112); a reverse lead screw (3322) is fixedly connected to the clamping drive motor (3321) in a coaxial manner; a set of clamping drive sliders (3323) are connected to the reverse lead screw (3322) in a reverse linear transmission; a heat sealing clamping head (3324) is fixedly connected to the clamping drive slider (3323); and a heating part (3325) is provided on the side of the heat sealing clamping head (3324) facing the direction. A slightly convex cutting blade (3326) is horizontally arranged on the side of the heating part (3325) of the uppermost heat sealing component (332).

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