A device and assembly for treating vascular compression neuropathies

Abstract

The present application belongs to the technical field of medical devices, and particularly relates to a device for treating blood vessel compression nerve diseases and an assembly. The device for treating blood vessel compression nerve diseases is in a hollow tubular shape, and is a closed loop correction part with mesh holes on the surface. The closed loop correction part is a metal stent, and the metal coverage is 10%-30%. The diameter of the closed loop correction part in an expanded state is 2.0mm-6.5mm, and the axial length of the closed loop correction part in the expanded state is 10mm-80mm. The material of the closed loop correction part is a shape memory alloy. The device for treating blood vessel compression nerve diseases can solve the problem of'responsible blood vessels' compressing nerves, and can also complete the operation through a vascular intervention operation mode, so as to leave no scar on the head and neck of the patient, and enable patients who are not suitable for surgical operation to be treated.

Description

Technical Field

[0001] This invention belongs to the field of medical device technology, specifically relating to a device and components for treating diseases caused by vascular compression of nerves. Background Technology

[0002] Trigeminal neuralgia is the most common vascular nerve compression disorder, characterized by recurrent paroxysmal severe pain in the distribution area of ​​the trigeminal nerve on one side of the face. Its incidence increases with age. Trigeminal neuralgia mostly occurs in middle-aged and elderly people, and is more common on the right side than the left. The disease is characterized by sudden onset and cessation of intense, lightning-like, stabbing, burning, persistent, and unbearable pain in the distribution area of ​​the trigeminal nerve in the head and face. Speaking, washing the face, brushing teeth, a gentle breeze, or even walking can trigger paroxysmal severe pain. The pain lasts for seconds or minutes, and occurs periodically, with normal intervals between attacks.

[0003] The etiology and pathogenesis of trigeminal neuralgia remain inconclusive, and no single theory can explain its clinical symptoms. Currently, the most supported theories are the microvascular compression of the trigeminal nerve leading to demyelination and the epileptiform neuralgia theory.

[0004] Currently, the commonly used treatment methods are drug therapy and surgical treatment. Among them, drug therapy cannot cure the disease.

[0005] There are three types of surgical treatment methods used clinically:

[0006] 1. Trigeminal nerve and Gasserian ganglion block: In 1903, Schosser pioneered the use of peripheral branch block of the trigeminal nerve to treat trigeminal neuralgia. The surgery involves injecting medication directly onto the trigeminal nerve, causing degeneration and conduction block, thus relieving pain. Commonly used blocking medications are anhydrous alcohol and glycerin. Peripheral branch block is simple to perform, but its effects are not long-lasting, generally lasting 3-8 months, rarely exceeding one year. Gasserian ganglion block is relatively complex and can cause complications such as neurokeratitis. The overall effective rate is 72%-99%, with an early recurrence rate of 20% and a recurrence rate of up to 50% after 5-10 years.

[0007] 2. Percutaneous radiofrequency thermocoagulation of the trigeminal ganglion is a safe, simple, and easily accepted treatment method with an efficacy rate of up to 90%. Its theoretical basis is the selective destruction of pain fibers within the trigeminal nerve while preserving tactile fibers. The procedure involves inserting a radiofrequency needle electrode into the trigeminal ganglion under X-ray or CT guidance, gradually heating it to 65℃–75℃ after applying current to destroy the target area for 60 seconds. This method is suitable for elderly patients or those who cannot or refuse craniotomy.

[0008] 3. Microvascular decompression (MVD): MVD surgery is currently the preferred surgical treatment for primary trigeminal neuralgia. First proposed by Professor Jannetta in 1967, the indications for the surgery include: confirmed by imaging examination that the trigeminal nerve is compressed by a blood vessel; patients who are willing to undergo surgery despite poor response to other treatments; and the blood vessel compressing the trigeminal nerve and causing pain is referred to as the "responsible vessel."

[0009] Commonly responsible blood vessels include:

[0010] ① Superior cerebellar artery (75%): The superior cerebellar artery can form a vascular loop extending caudally, which contacts the point where the trigeminal nerve enters the brainstem, mainly compressing the nerve root above or above and medially.

[0011] ② Anterior inferior cerebellar artery (10%): Generally, the anterior inferior cerebellar artery compresses the trigeminal nerve from below, and it may also work together with the superior cerebellar artery to clamp and compress the trigeminal nerve.

[0012] ③ The basilar artery, with the increase of age and the influence of hemodynamics, can bend to both sides and compress the trigeminal nerve root, generally bending towards the smaller vertebral artery.

[0013] ④ Other less common culprit vessels include the posterior inferior cerebellar artery, variant vessels (such as the persistent trigeminal artery), transverse pontine veins, lateral veins, and the basal venous plexus. The culprit vessel can be one or more, and can be either an artery or a vein.

[0014] The procedure for microvascular decompression (MVD) involves making a 4cm longitudinal incision behind the ear and within the hairline on the affected side under general anesthesia. A 2cm diameter opening is made in the skull, allowing access to the cerebellopontine angle under a microscope. The area along the trigeminal nerve is explored, and all potentially compressive blood vessels and arachnoid cords are released. These vessels are then isolated from the nerve root using Tefflon pads. Once the responsible vessel is isolated, the source of irritation disappears, and the hyperexcitability of the trigeminal nucleus subsides, restoring normal function. Most patients experience immediate pain relief post-surgery, retaining normal facial sensation and function without affecting their quality of life. However, MVD is an invasive open surgical procedure, unsuitable for all patients. Furthermore, with rising living standards, open surgery on the head and neck inevitably leaves scars, and aesthetic concerns also impact patients' psychological well-being. Therefore, if a less invasive interventional procedure could achieve similar results, it would offer patients both physical and psychological benefits.

[0015] Therefore, there is a need to provide an improved technical solution that addresses the shortcomings of the existing technology. Summary of the Invention

[0016] The purpose of this invention is to provide a device and components for treating vascular compression-related nerve diseases. The inventors discovered in their research that straightening the blood vessel reduces the compression of the trigeminal nerve by the "responsible blood vessel," effectively improving trigeminal neuralgia. Furthermore, the inventors found that if a stent can be applied to the trigeminal nerve to provide appropriate support for the tortuous blood vessel, straightening the vessel can be achieved. A device for treating vascular compression-related nerve diseases has been further developed to solve or improve the problem of the "responsible blood vessel" compressing the trigeminal nerve. In addition, the device for treating vascular compression-related nerve diseases of this invention can also be used to treat hemifacial spasm.

[0017] To achieve the above objectives, the present invention provides the following technical solution: a device for treating vascular compression of nerve diseases, wherein the closed-loop correction part is a hollow tube with a mesh surface; the closed-loop correction part is a metal support with a metal coverage of 10%-30%; the diameter of the closed-loop correction part in its expanded state is 2.0mm-6.5mm, and the axial length of the closed-loop correction part in its expanded state is 10mm-80mm; the material of the closed-loop correction part is a shape memory alloy.

[0018] Preferably, the mesh is evenly distributed on the surface of the closed-loop correction part, and the diameter of the largest inscribed circle of a single mesh is 0.5mm-1.0mm.

[0019] Preferably, the area of ​​a single mesh opening is 1.0 mm. 2 -2.0mm 2 .

[0020] Preferably, the mesh is rhomboid in shape, and the interior angles of the mesh include acute angles of 15°-90°.

[0021] Preferably, the inner angles of the mesh include acute angles of 30°-45°.

[0022] Preferably, the closed-loop correction unit is composed of interconnected support rods, and the radial dimension of the support rods is 0.03mm-0.10mm.

[0023] Preferably, the radial dimension of the support rod is 0.05mm-0.07mm.

[0024] Preferably, the closed-loop correction section is a constant-diameter bracket, and the material of the closed-loop correction section is NiTi alloy, stainless steel or cobalt-chromium alloy; the closed-loop correction section is also provided with developing points, and the developing points are located at both ends and / or the middle position of the closed-loop correction section in the axial direction of the closed-loop correction section.

[0025] The present invention also provides a component for treating vascular compression of nerve diseases, which adopts the following technical solution: a component for treating vascular compression of nerve diseases, including the device as described above, and further including: a delivery guidewire, wherein the closed-loop correction part is pre-assembled on the delivery guidewire; and an inlet sheath, wherein the delivery guidewire and the closed-loop correction part are pre-assembled and then pressed into the inlet sheath.

[0026] Beneficial effects:

[0027] The device for treating nerve compression diseases caused by blood vessels of the present invention can not only solve the problem of nerve compression by the "responsible blood vessel", but also complete the surgery through vascular intervention, leaving no scars on the patient's head and neck, so that patients who are not suitable for surgery can also be treated.

[0028] The device of this invention for treating nerve compression caused by blood vessels has the function of straightening blood vessels. After straightening the "responsible blood vessel" that was originally compressing the trigeminal nerve, the "responsible blood vessel" changes its original position and no longer compresses the trigeminal nerve, thereby eliminating the compression and resolving the patient's trigeminal neuralgia. This device can also be used to treat hemifacial spasm. Attached Figure Description

[0029] The accompanying drawings, which form part of this application, are used to provide a further understanding of the invention. The illustrative embodiments of the invention and their descriptions are used to explain the invention and do not constitute an undue limitation of the invention. Wherein:

[0030] Figure 1 This is a schematic diagram of the structure of a device for treating nerve compression diseases caused by blood vessels, according to an embodiment of the present invention;

[0031] Figure 2 This is a schematic diagram of a device for treating nerve-related diseases caused by vascular compression, provided in another embodiment of the present invention;

[0032] Figure 3 This is a schematic diagram of the device for treating nerve compression diseases caused by blood vessels, provided in another embodiment of the present invention;

[0033] Figure 4 This is a schematic diagram of the device for treating nerve compression diseases caused by blood vessels, provided in another embodiment of the present invention;

[0034] Figure 5 This is a schematic diagram of the structure of a component for treating nerve-related diseases caused by vascular compression, provided in one embodiment of the present invention (the closed-loop correction unit is not retrievable after complete release);

[0035] Figure 6This is a schematic diagram of the structure of a device for treating vascular compression of nerve diseases provided in an embodiment of the present invention before and after release (fully released and retrievable closed-loop correction unit);

[0036] Figure 7 This is a DSA image of the device for treating nerve compression diseases caused by blood vessels, provided in one embodiment of the present invention, before implantation into a blood vessel;

[0037] Figure 8 The image provided is a DSA image of the device for treating nerve compression diseases caused by blood vessels after implantation in a blood vessel, according to one embodiment of the present invention.

[0038] Figure label:

[0039] 1-Closed-loop correction section; 11-Mesh; 12-Support rod; 121-Developing point; 13-Reinforcing rib; 2-Transport guide wire; 3-Introduction sheath; 4-Distal developing spring; 5-Support positioning spring; 6-Proximal developing spring. Detailed Implementation

[0040] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention are within the scope of protection of the present invention.

[0041] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting this invention.

[0042] In the description of this invention, "several" means one or more, "more than" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.

[0043] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" and "second" may explicitly or implicitly include one or more features.

[0044] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the term "connection" should be interpreted broadly. For example, it can be a fixed connection or a movable connection, a detachable connection or a non-detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection or a connection that allows communication between the two components; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components, an indirect connection, or an interaction between two components.

[0045] The present invention will now be described in detail with reference to embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in the embodiments of the present invention can be combined with each other.

[0046] In the following description of the device for treating vascular compression of nerve diseases of the present invention, the end closer to the operator is the proximal end, and the end farther from the operator is the distal end.

[0047] The inventors discovered in their research that straightening blood vessels reduces the compression of the trigeminal nerve by "responsible vessels" (superior cerebellar artery, inferior cerebellar artery, basilar artery, inferior cerebellar artery, variant vessels, transverse pontine vein, lateral vein, and basilar venous plexus, etc.), which can effectively improve trigeminal neuralgia. Furthermore, the inventors found that if a stent can be applied to the trigeminal nerve to provide appropriate support for tortuous blood vessels, the blood vessels can be straightened. They further developed a device that can be used to treat diseases caused by vascular compression of the nerve, in order to solve or improve the problem of "responsible vessels" compressing the trigeminal nerve.

[0048] The device of the present invention for treating vascular compression of nerve diseases, such as Figure 1-2As shown, the device for treating vascular compression of nerve diseases is a hollow tube with a closed-loop correction section 1 having a mesh 11 on its surface. The device for treating vascular compression of nerve diseases of the present invention is a metal stent with a metal coverage of 10%-30% (e.g., 10%, 12%, 15%, 17%, 19%, 21%, 23%, 25%, 28% or 30%). The diameter of the closed-loop correction section 1 in its expanded state is 2.0mm-6.5mm (e.g., 2.0mm, 3.0mm, 4.0mm, 5.0mm, 6.0mm or 6.5mm), and the axial length of the closed-loop correction section 1 in its expanded state is 10mm-80mm (e.g., 10mm, 20mm, 30mm, 40mm, 50mm, 60mm, 70mm or 80mm). The material of the closed-loop correction section 1 is a shape memory alloy. By ensuring the metal coverage of the closed-loop correction unit 1 is 10%-30% (in this invention, the metal coverage of the closed-loop correction unit 1 is high, requiring a metal coverage of over 10%), the flexibility of the closed-loop correction unit 1 is appropriate, enabling it to straighten blood vessels. This allows the device for treating vascular compression-related nerve diseases of this invention to be delivered to the "responsible blood vessel," straightening the vessel and treating or improving trigeminal neuralgia. The device for treating vascular compression-related nerve diseases of this invention can also be used to treat hemifacial spasm.

[0049] The device for treating nerve compression diseases caused by vascular vascular compression of the present invention can be laser-engraved and is a non-degradable stent. This device is an implantable vascular stent (e.g., implanted at the target vascular location via vascular intervention), and the closed-loop correction unit 1 can be placed in arteries and veins. This device not only solves the problem of nerve compression by the "responsible vessel," but also allows for surgical procedures via vascular intervention, leaving no scars on the patient's head and neck, thus enabling treatment even for patients unsuitable for surgery.

[0050] In a preferred embodiment of the device for treating nerve compression diseases caused by blood vessels according to the present invention, mesh openings 11 are uniformly distributed on the surface of the closed-loop correction section 1, and the diameter of the largest inscribed circle of a single mesh opening 11 is 0.5mm-1.0mm (e.g., 0.5mm, 0.6mm, 0.7mm, 0.8mm, 0.9mm, or 1.0mm). The size of the mesh openings 11 affects the overall support and flexibility of the closed-loop correction section 1, thereby affecting its effect on straightening blood vessels.

[0051] In a preferred embodiment of the device for treating nerve compression diseases caused by blood vessels according to the present invention, the area of ​​a single mesh 11 is 1.0 mm. 2 -2.0mm 2 (For example, 1.0mm) 2 1.2mm 2 1.4mm2 1.6mm 2 1.8mm 2 or 2.0mm 2 The inventors discovered during their research that when the area of ​​a single mesh 11 is 1.0 mm... 2 -2.0mm 2 At the same time, the closed-loop correction unit 1 can not only be smoothly delivered to the target blood vessel, but also effectively straighten the blood vessel.

[0052] In a preferred embodiment of the device for treating vascular compression-related nerve diseases of the present invention, the mesh 11 is rhomboid in shape, and the interior angles of the mesh 11 include acute angles of 15°-90° (e.g., 15°, 20°, 25°, 30°, 35°, 40°, 45°, 50°, 55°, 60°, 65°, 70°, 75°, 80°, 85°, or 90°). Figure 1 (As shown by the included angle α). The inventors discovered in their research that the shape of the mesh 11 also affects its effect on straightening blood vessels. Specifically, when the mesh 11 is rhomboid in shape, the larger the acute angle of the rhombus, the better the flexibility of the closed-loop correction part 1, but its straightening effect on blood vessels weakens. When the acute angle of the rhombus is between 15° and 90°, it can improve or treat trigeminal neuralgia and hemifacial spasm.

[0053] Preferably, the mesh 11 can also be in a rhombus-like shape, the only difference being that the interior angles of the rhombus-like mesh 11 are rounded (e.g., ...). Figure 1 (As shown).

[0054] In a preferred embodiment of the device for treating vascular compression of nerve diseases of the present invention, the interior angle of the mesh 11 includes an acute angle of 30°-45° (e.g., 30°, 32°, 34°, 36°, 38°, 41°, 42°, 43°, 44° or 45°) (i.e., the acute angle α in the rhomboid mesh 11 is 30°-45°).

[0055] In a preferred embodiment of the device for treating nerve compression diseases caused by blood vessels according to the present invention, the closed-loop correction unit 1 is composed of interconnected support rods 12, the radial dimension of which is 0.03mm-0.10mm (e.g., 0.03mm, 0.04mm, 0.05mm, 0.06mm, 0.07mm, 0.08mm, 0.09mm, or 0.1mm). The cross-section of the support rod 12 perpendicular to its axis can be rectangular or circular (when the cross-section of the support rod 12 is rectangular, its length and / or width is 0.03mm-0.10mm; when the cross-section of the support rod 12 is circular, its closed-loop correction unit 1 is 0.03mm-0.10mm), etc., and is not specifically limited here. The radial dimension of the support rod 12 affects the overall support of the closed-loop correction unit 1, which in turn affects the straightening effect of the closed-loop correction unit 1 on the blood vessels, thus affecting the therapeutic effect on trigeminal neuralgia or hemifacial spasm.

[0056] In a preferred embodiment of the device for treating vascular compression of nerve diseases of the present invention, a reinforcing rib 13 is further provided in the direction from the proximal end to the distal end (or from the distal end to the proximal end) of the closed-loop correction section 1, and the reinforcing rib 13 is disposed through the connection point of the support rod 12. The number of reinforcing ribs 13 can be one or more (two or more); the reinforcing rib 13 can penetrate the entire closed-loop correction section 1. Figure 3 Alternatively, it can be located at the distal end of the closed-loop correction unit 1, with the distal end occupying 1 / 2 of the total length of the closed-loop correction unit 1. Figure 4 In medical practice, it has been found that in the process of vascular correction, some cases only require correction of a small segment of the blood vessel. Correcting an excessively long segment may cause other complications. For other parts of the blood vessel, the closed-loop correction unit 1 only needs to conform to the vessel wall. "The connection point setting of the reinforcing rib through the stent rod" refers to the apex of the line connecting the proximal to distal end of the reinforcing rib 13 through the mesh 11. The setting of the reinforcing rib 13 helps the closed-loop correction unit 1 to have better expansion and support performance after being delivered into the blood vessel, thereby better straightening the blood vessel, reducing or avoiding the compression of the trigeminal nerve by the blood vessel, and improving the treatment effect of trigeminal neuralgia and hemifacial spasm.

[0057] In a preferred embodiment of the device for treating nerve compression diseases caused by blood vessels according to the present invention, the radial dimension of the support rod 12 is 0.05mm-0.07mm (e.g., 0.05mm, 0.052mm, 0.054mm, 0.056mm, 0.058mm, 0.062mm, 0.064mm, 0.066mm, 0.068mm or 0.07mm).

[0058] In a preferred embodiment of the device for treating vascular compression of nerve diseases of the present invention, the closed-loop correction section 1 is a constant-diameter stent, and the material of the closed-loop correction section 1 is NiTi alloy, stainless steel, or cobalt-chromium alloy; the closed-loop correction section 1 is also provided with imaging points 121 (for example, imaging points 121 can be radiopaque metal imaging points 121), and the imaging points 121 are located at both ends and / or the middle position of the closed-loop correction section 1 along the axial direction of the closed-loop correction section 1. Here, "constant-diameter stent" means that the radial dimension of the closed-loop correction section 1 is the same at different positions along the axial direction of the closed-loop correction section 1, and the diameter of the closed-loop correction section 1 at both ends and the middle remains consistent without any change in diameter.

[0059] In a preferred embodiment of the device for treating vascular compression of nerve diseases of the present invention, imaging points 121 are disposed on spaced support rods 12 in the radial and / or axial directions (e.g., imaging points are disposed once every one or more support rods; or, imaging points are disposed once every one or more mesh openings; see reference). Figure 2 Preferably, the imaging points 121 are arranged in pairs (i.e., two imaging points 121 are provided on the same support rod 12). In the device for treating vascular compression of nerve diseases of the present invention, the arrangement of imaging points 121 helps the operator to determine the location of the closed-loop correction unit under interventional surgical conditions, determine whether the closed-loop correction unit has reached the target blood vessel, and better observe the straightening effect of the closed-loop correction unit 1 on the "responsible blood vessel" after implantation, which facilitates the determination of whether the device for treating vascular compression of nerve diseases of the present invention has achieved blood vessel straightening.

[0060] In a preferred embodiment of the device for treating vascular compression of nerve diseases of the present invention, the closed-loop correction part 1 is made of NiTi alloy and is laser-engraved to have straight ends without flaring.

[0061] In a preferred embodiment of the device for treating vascular compression of nerve diseases of the present invention, the device is cylindrical and cannot be unfolded into a plane. The closed-loop correction part 1 can also be a curled cylinder. Along a certain axis position on the side of the stent, the stent can be fully unfolded into a plane (that is, when the closed-loop correction part 1 is retracted into the small inner diameter sheath, the closed-loop correction part 1 can be curled up more severely, similar to a scroll painting, curled into a thin tube, which can enter the inlet sheath to realize interventional delivery).

[0062] The device of the present invention for treating nerve-related diseases caused by vascular compression is applied to the "responsible blood vessel". Figure 7 This is a DSA image taken before the closed-loop correction unit 1 was implanted into a blood vessel. Figure 8 DSA images of the closed-loop correction unit 1 after implantation of a blood vessel; comparison Figure 7 and Figure 8It is understood that the device for treating nerve compression diseases caused by blood vessels of the present invention has the function of straightening blood vessels. After straightening the "responsible blood vessel" that was originally compressing the trigeminal nerve, the "responsible blood vessel" changes its original position and no longer compresses the trigeminal nerve, thereby achieving the effect of eliminating compression and resolving the patient's trigeminal neuralgia or facial muscle spasm problem.

[0063] The present invention also proposes a component for treating vascular compression of nerve diseases, including the device for treating vascular compression of nerve diseases as described above, and further comprising: a delivery guidewire 2, with a closed-loop correction unit 1 pre-assembled on the delivery guidewire 2; and an insertion sheath 3, in which the delivery guidewire 2 and the closed-loop correction unit 1 are pre-assembled and then pressed into the insertion sheath 3 (see reference). Figure 6 ).

[0064] In a preferred embodiment of the component for treating vascular compression of nerve diseases of the present invention, a distal imaging spring 4 is provided at the distal end of the delivery guidewire 2, and a proximal imaging spring 6 is provided at the proximal end of the delivery guidewire 2 (the proximal imaging spring 6 can be connected to the delivery guidewire 2 by welding). A stent positioning spring 5 (one or more can be provided as needed) is also provided between the distal imaging spring 4 and the proximal imaging spring 6 to facilitate determining whether the device for treating vascular compression of nerve diseases of the present invention has been delivered in place.

[0065] Preferably, the component for treating vascular compression of nerve diseases of the present invention further includes a microcatheter (not shown in the figure, but a suitable microcatheter in the prior art can be used). The microcatheter can be disposed at the distal end of the inlet sheath 3. The hollow inner lumen of the microcatheter is connected to the inlet sheath 3 so as to push the device for treating vascular compression of nerve diseases into the microcatheter by pushing the delivery guidewire 2, and then deliver and release it into the target blood vessel through the microcatheter.

[0066] Furthermore, the device of the present invention for treating vascular compression-related nerve diseases can be a closed-loop correction unit that is not retrievable after complete release (e.g., Figure 6 (as shown); or, a closed-loop correction unit 1 that can be recovered after complete release (as shown). Figure 6 (As shown). The device for treating vascular compression-related nerve diseases of the present invention may have no release point from the delivery system, or it may have a release point from the delivery system. Separation between the closed-loop correction unit 1 and the delivery system can be achieved by electrical or mechanical release (using the corresponding technical solutions in the prior art).

[0067] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the present invention by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. A device for treating nerve compression diseases caused by blood vessels, characterized in that, The device is a hollow tube and is a closed-loop correction part with a mesh surface; the closed-loop correction part is a metal support with a metal coverage of 10%-30%; the diameter of the closed-loop correction part in the expanded state is 2.0mm-6.5mm, and the axial length of the closed-loop correction part in the expanded state is 10mm-80mm; the material of the closed-loop correction part is shape memory alloy. The closed-loop correction unit is composed of interconnected support rods, the radial dimension of which is 0.03mm-0.10mm; A reinforcing rib is also provided in the direction from the proximal end to the distal end of the closed-loop correction section. The reinforcing rib is provided through the connection point of the support rod. There are one or more reinforcing ribs. The reinforcing rib is provided throughout the closed-loop correction section or at the distal end of the closed-loop correction section. The distal end accounts for 1 / 2 of the total length of the closed-loop correction section.

2. The device for treating nerve compression diseases caused by blood vessels as described in claim 1, characterized in that, The mesh is evenly distributed on the surface of the closed-loop correction part, and the diameter of the largest inscribed circle of a single mesh is 0.5mm-1.0mm.

3. The device for treating nerve compression diseases caused by blood vessels as described in claim 1, characterized in that, The area of ​​a single mesh opening is 1.0 mm² to 2.0 mm².

4. The device for treating nerve compression diseases caused by blood vessels as described in claim 1, characterized in that, The mesh is rhomboid in shape, and the interior angles of the mesh include acute angles ranging from 15° to 90°.

5. The device for treating nerve compression diseases as described in claim 4, characterized in that, The inner angles of the mesh include acute angles of 30°-45°.

6. The device for treating nerve compression diseases as described in claim 1, characterized in that, The radial dimension of the support rod is 0.05mm-0.07mm.

7. The device for treating nerve compression diseases caused by blood vessels as described in any one of claims 1-6, characterized in that, The closed-loop correction section is a constant-diameter bracket, and the material of the closed-loop correction section is NiTi alloy, stainless steel or cobalt-chromium alloy; the closed-loop correction section is also provided with developing points, and the developing points are located at both ends and / or the middle position of the closed-loop correction section along the axial direction of the closed-loop correction section.

8. A component for treating nerve compression diseases caused by blood vessels, characterized in that, The device, including any one of claims 1-7, further includes: a delivery guide wire, wherein the closed-loop correction unit is pre-assembled on the delivery guide wire; and an inlet sheath, wherein the delivery guide wire and the closed-loop correction unit are pre-assembled and then pressed into the inlet sheath.

Images