Storage control methods for biological sample storage systems and biological sample storage systems

Abstract

This invention relates to the field of biological sample storage technology, specifically providing a storage control method and a biological sample storage system. It aims to solve the problem in existing technologies where storing multiple samples in different devices requires manual pre-division of the samples into multiple portions and separate storage operations, which is cumbersome and time-consuming. To address this, the storage control method of this invention includes: determining the storage type corresponding to the current storage operation based on the sample storage instruction; selectively executing a single-zone storage mode or a partitioned storage mode based on the storage type; and, in cases where the storage type cannot be determined, selectively executing a single-zone storage mode or a partitioned storage mode based on the total number of samples to be stored and the sample information of each sample. The storage control method of this invention can automatically determine and execute the storage mode, saving time and improving storage efficiency and sample security.

Description

Technical Field

[0001] This invention relates to the field of biological sample storage technology, and specifically provides a storage control method and a biological sample storage system. Background Technology

[0002] In the biomedical industry, automated ultra-low temperature equipment is needed to store biological samples. When there are many samples or to mitigate storage risks, multiple automated storage devices are usually required. Each automated storage device is relatively independent. When multiple samples need to be stored separately, the samples must first be divided into multiple portions and each portion must be stored in a different automated storage device, thus performing multiple storage operations. This is cumbersome and time-consuming.

[0003] Accordingly, a new technical solution is needed in this field to solve the above-mentioned technical problems. Summary of the Invention

[0004] The present invention aims to solve the above-mentioned technical problems, namely, to solve the problem that in the prior art, storing multiple samples into different devices requires manual division of multiple samples into multiple portions in advance and storage operations are performed separately, which is cumbersome and time-consuming.

[0005] In a first aspect, the present invention provides a storage control method for a biological sample storage system, the biological sample storage system comprising multiple storage repositories spaced along a linear structure, adjacent storage repositories being sealed and connected by a connecting channel and capable of transferring cryopreservation boxes between them; the storage control method comprising: acquiring a sample storage instruction; receiving a source cryopreservation box carrying samples to be stored; determining the storage type corresponding to the current storage operation based on the sample storage instruction; selectively executing a single-zone storage mode or a partitioned storage mode based on the storage type; in the case where the storage type cannot be determined, acquiring the total number of samples to be stored and the sample information of each sample to be stored, and selectively executing the single-zone storage mode or the partitioned storage mode based on the total number of samples to be stored and the sample information of each sample to be stored; wherein, the single-zone storage mode stores all samples to be stored in the same source cryopreservation box into the same storage repository; the partitioned storage mode stores multiple samples to be stored in the same source cryopreservation box into at least two storage repositories.

[0006] In the preferred embodiment of the storage control method of the above-mentioned biological sample storage system, the step of "determining the storage type corresponding to this storage operation based on the sample storage instruction" specifically includes: determining the total number of samples to be stored and the target storage location of each sample to be stored based on the sample storage instruction; and determining the storage type corresponding to this storage operation based on the total number of samples to be stored and / or multiple target storage locations.

[0007] In the preferred embodiment of the storage control method of the above-mentioned biological sample storage system, the step of "determining the storage type corresponding to this storage operation based on the total number of samples to be stored and / or multiple target storage locations" specifically includes: determining whether the total number of samples to be stored is greater than 1; if the determination result is "no", then the storage type corresponding to this storage operation is determined to be a single-zone storage type; if the determination result is "yes", then determining whether multiple storage locations are located in the same storage repository; if multiple storage locations are located in the same storage repository, then the storage type corresponding to this storage operation is determined to be a single-zone storage type; if multiple storage locations are not located in the same storage repository, then the storage type corresponding to this storage operation is determined to be a partitioned storage type.

[0008] In the preferred embodiment of the storage control method for the above-mentioned biological sample storage system, the step of "selectively executing a single-zone storage mode or a partitioned storage mode based on the storage type" specifically includes: if the storage type is a single-zone storage type, then the single-zone storage mode is executed; if the storage type is a partitioned storage type, then the partitioned storage mode is executed.

[0009] In the preferred embodiment of the storage control method of the above-mentioned biological sample storage system, the step of "selectively executing the single-zone storage mode or the partitioned storage mode based on the total number of samples to be stored and the sample information of each sample to be stored" specifically includes: determining whether the total number of samples to be stored is greater than 1; if the total number of samples to be stored is not greater than 1, then executing the single-zone storage mode; if the total number of samples to be stored is greater than 1, then determining the number of types of samples to be stored and the number of samples to be stored corresponding to each type of sample to be stored based on the sample information of each sample to be stored, and selectively executing the single-zone storage mode or the partitioned storage mode based on the number of types of samples to be stored and the number of samples to be stored corresponding to each type of sample to be stored.

[0010] In the preferred embodiment of the storage control method of the above-mentioned biological sample storage system, the step of "selectively executing the single-zone storage mode or the partitioned storage mode according to the number of types of samples to be stored and the number of samples to be stored corresponding to each type" specifically includes: determining whether the number of types of samples to be stored is greater than 1; if the determination result is "yes", then determining whether the number of samples to be stored corresponding to each type is greater than 1, and selectively executing the single-zone storage mode or the partitioned storage mode according to the determination result of whether the number of samples to be stored corresponding to each type is greater than 1; if the determination result is "no", then executing the partitioned storage mode.

[0011] In the preferred embodiment of the storage control method of the above-mentioned biological sample storage system, the step of "selectively executing the single-zone storage mode or the partitioned storage mode according to the judgment result of whether the number of samples to be stored corresponding to each type of sample is greater than 1" specifically includes: if the number of samples to be stored corresponding to all types of samples is not greater than 1, then the single-zone storage mode is executed; if the number of samples to be stored corresponding to any type of sample is greater than 1, then the partitioned storage mode is executed.

[0012] In the preferred embodiment of the storage control method of the above-mentioned biological sample storage system, when the storage type can be determined, the step of "executing the single-zone storage mode" specifically includes: moving the source cryopreservation box to the tube picking station; determining the target cryopreservation box corresponding to each sample to be stored based on each target storage location; moving the target cryopreservation box to the tube picking station; moving the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box; returning the target cryopreservation box to its original storage location after scanning the code; and / or, when the storage type can be determined. The steps of "executing the partitioned storage mode" specifically include: moving the source cryopreservation box to the tube picking station; determining the target cryopreservation box corresponding to each sample to be stored based on each target storage location; determining the tube picking order of each target cryopreservation box based on the distance relationship between the storage repository where each target cryopreservation box is located and the tube picking station; moving each target cryopreservation box to the tube picking station in sequence according to the tube picking order; moving the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box; and returning the target cryopreservation box to its original storage location after scanning the code.

[0013] In the preferred embodiment of the storage control method of the above-mentioned biological sample storage system, when the storage type cannot be determined, the step of "executing the single-zone storage mode" specifically includes: moving the source cryopreservation box to the tube picking station; obtaining the available storage information of each of the storage repositories; determining the target storage repository and target cryopreservation box of the sample to be stored based on the available storage information of each of the storage repositories; moving the target cryopreservation box out of the target storage repository and to the tube picking station; moving the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box; scanning the code and returning the target cryopreservation box to its original storage location in the target storage repository; and / or, when the storage type cannot be determined... In this case, the steps of "executing the partitioned storage mode" specifically include: moving the source cryopreservation box to the tube-picking station; obtaining the free storage information of each of the storage repositories; determining the target storage repository and target cryopreservation box corresponding to each sample to be stored based on the free storage information of each of the storage repositories; determining the tube-picking order of each target cryopreservation box based on the distance relationship between each target storage repository and the tube-picking station; moving each target cryopreservation box to the tube-picking station in sequence according to the tube-picking order; moving the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box; and returning the target cryopreservation box to its original storage location in the target storage repository after scanning the code.

[0014] In a second aspect, the present invention provides a biological sample storage system, the biological sample storage system including a controller configured to execute the storage control method of the biological sample storage system described above.

[0015] With the above technical solution, the biosample storage system of the present invention includes multiple storage containers spaced along a linear structure. Adjacent storage containers are sealed together by a connecting channel, and cryopreservation boxes can be transferred between adjacent storage containers. The storage control method of the present invention includes: acquiring a sample storage instruction; receiving a source cryopreservation box carrying the sample to be stored; determining the storage type corresponding to this storage operation based on the sample storage instruction; selectively executing a single-zone storage mode or a partitioned storage mode based on the storage type; in the case where the storage type cannot be determined, acquiring the total number of samples to be stored and the sample information of each sample to be stored, and selectively executing a single-zone storage mode or a partitioned storage mode based on the total number of samples to be stored and the sample information of each sample to be stored. This configuration allows multiple samples to be stored to be placed in a single source cryopreservation box and input into the storage container through a single source cryopreservation box. The biosample storage system then automatically determines whether to execute a single-zone storage mode or a partitioned storage mode, and automatically performs the storage. Even if multiple samples need to be stored in different storage containers, there is no need for manual pre-allocation of the samples to be stored, thereby saving time and improving storage efficiency.

[0016] Furthermore, the step of "determining the storage type corresponding to this storage operation based on the sample storage instruction" specifically includes: determining the total number of samples to be stored and the target storage location of each sample based on the sample storage instruction; determining the storage type corresponding to this storage operation based on the total number of samples to be stored and / or multiple target storage locations; this setting method determines the storage type through the information contained in the sample storage instruction so as to execute the storage mode corresponding to the storage type, which is simple to determine and easy to control.

[0017] Furthermore, the step of "determining the storage type corresponding to this storage operation based on the total number of samples to be stored and / or multiple target storage locations" specifically includes: determining whether the total number of samples to be stored is greater than 1; if the determination result is "no", then the storage type corresponding to this storage operation is determined to be a single-zone storage type; if the determination result is "yes", then determining whether multiple storage locations are located in the same repository; if multiple storage locations are located in the same repository, then the storage type corresponding to this storage operation is determined to be a single-zone storage type; if multiple storage locations are not located in the same repository, then the storage type corresponding to this storage operation is determined to be a partitioned storage type. This setting method first determines whether the total number of samples to be stored is greater than 1, and if it is greater than 1, then determines whether multiple storage locations are located in the same repository, thereby improving the accuracy of the determination result, avoiding misjudgment, and the determination process is simple and fast.

[0018] Furthermore, the step of "selectively executing single-area storage mode or partitioned storage mode based on the total number of samples to be stored and the sample information of each sample to be stored" specifically includes: determining whether the total number of samples to be stored is greater than 1; if the total number of samples to be stored is not greater than 1, then executing single-area storage mode; if the total number of samples to be stored is greater than 1, then determining the number of types of samples to be stored and the number of samples to be stored corresponding to each type based on the sample information of each sample to be stored, and then selectively executing single-area storage mode or partitioned storage mode based on the number of types of samples to be stored and the number of samples to be stored corresponding to each type. This setting method first determines whether the total number of samples to be stored is greater than 1. If it is not greater than 1, single-area storage mode is executed. If it is greater than 1, then it determines whether partitioned storage is needed based on the number of types of samples to be stored and the number of samples to be stored corresponding to each type. This simplifies the judgment logic and effectively improves the accuracy of the judgment.

[0019] Furthermore, the step of "selectively executing single-area storage mode or partitioned storage mode based on the number of types of samples to be stored and the corresponding storage quantity for each type of sample" specifically includes: determining whether the number of types of samples to be stored is greater than 1; if the determination result is "yes", then determining whether the corresponding storage quantity for each type of sample is greater than 1, and selectively executing single-area storage mode or partitioned storage mode based on the determination result of whether the corresponding storage quantity for each type of sample is greater than 1; if the determination result is "no", then executing partitioned storage mode. This setting method first determines whether the number of types of samples to be stored is greater than 1. If it is not greater than 1, partitioned storage mode is executed; if it is greater than 1, then single-area storage mode or partitioned storage mode is selectively executed based on the determination result of whether the corresponding storage quantity for each type of sample is greater than 1. The entire determination process is simple and has high accuracy. Attached Figure Description

[0020] The preferred embodiments of the present invention are described below with reference to the accompanying drawings, in which:

[0021] Figure 1 This is a schematic diagram of the biological sample storage system of the present invention;

[0022] Figure 2 This is a structural schematic diagram of the main steps of the storage control method of the present invention;

[0023] Figure 3 This is a flowchart illustrating the specific execution steps of steps S3 and S4 in the storage control method of the present invention;

[0024] Figure 4 This is a flowchart illustrating the specific execution steps of step S6 in the storage control method of the present invention.

[0025] List of reference numerals in the attached diagram:

[0026] 1. Repository; 11. Cache area; 12. Storage area;

[0027] 2. Connecting channel; 3. Pipe picking equipment; 4. Storage rack; 5. Frozen storage area transfer robot; 6. First conveying mechanism; 7. Second conveying mechanism; 8. Transmission mechanism. Detailed Implementation

[0028] Preferred embodiments of the present invention will now be described with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are merely illustrative of the technical principles of the present invention and are not intended to limit the scope of protection of the present invention.

[0029] It should be noted that in the description of this invention, terms such as "inner" and "outer" indicating directional or positional relationships are based on the directional or positional relationships shown in the accompanying drawings. This is merely for ease of description and does not indicate or imply that the device or element must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation of this invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0030] Furthermore, it should be noted that, in the description of this invention, unless otherwise explicitly specified and limited, the terms "set" and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through other components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0031] As mentioned in the background section, storing multiple samples into different devices requires manual division of the samples into multiple portions and storage operations, which is cumbersome and time-consuming.

[0032] The biological sample storage system of the present invention includes multiple storage repositories distributed along a linear structure. Adjacent storage repositories are sealed together by a connecting channel, and cryopreservation boxes can be transferred between adjacent storage repositories. The storage control method of the present invention allows multiple samples to be stored to be placed in a single source cryopreservation box, with each storage repositories receiving only one source cryopreservation box. The biological sample storage system then automatically determines whether to execute a single-zone storage mode or a partitioned storage mode, and performs the storage automatically. Even if multiple samples need to be stored in different storage repositories, there is no need for manual pre-allocation of the samples to be stored, thereby saving time and improving storage efficiency.

[0033] Specifically, please refer to Figure 1 The biological sample storage system of the present invention includes multiple storage containers 1, which are distributed at intervals along a linear structure. Adjacent storage containers 1 are sealed and connected by a connecting channel 2, and cryopreservation boxes can be transferred between adjacent storage containers 1. Each storage container 1 is provided with an entrance / exit that connects to the external environment, enabling the transfer of cryopreservation boxes between the storage container 1 and the outside world. Each storage container 1 is equipped with an electric door to seal and open the entrance / exit, preventing the storage container 1 from connecting to the outside world when sealed.

[0034] In practical applications, the linear structure can be a straight line, a curved line, or a broken line. This invention does not impose any restrictions on the shape of the linear structure. Those skilled in the art can set the shape of the linear structure according to actual needs, as long as the adjacent two storage containers 1 are sealed through the connecting channel 2 along the extension direction of the linear structure and can transfer the cryopreservation boxes to each other.

[0035] Preferably, please continue reading. Figure 1 Each storage repository 1 includes an independent storage area 12 and a buffer area 11. Samples are stored in storage area 12. Storage areas 12 and buffer areas 11 within the same storage repository 1 can transfer cryopreservation boxes between each other. Specifically, storage areas 12 and buffer areas 11 are connected via a second electric door, allowing selective connection of storage areas 12 and buffer areas 11 for cryopreservation box transfer. A connecting channel 2 connects the buffer areas 11 of two adjacent storage repositories 1, enabling the transfer of cryopreservation boxes between the buffer areas 11 of adjacent storage repositories 1. Specifically, the storage temperature in storage area 12 is -80°C, and the storage temperature in buffer area 11 is -25°C. Storage area 12 is used for storing samples, while buffer area 11 is used for sample picking and transfer.

[0036] Connection channel 2 connects the buffer areas 11 of two adjacent storage tanks 1, so that both connection channel 2 and buffer area 11 are at -25°C. When the cryopreservation box is transferred through connection channel 2, the cryopreservation box can be kept at -25°C, effectively ensuring the safety of the sample.

[0037] Preferably, please continue reading. Figure 1 The biological sample storage system of the present invention also includes a transmission mechanism 8, which runs through the connecting channel 2 and connects multiple buffer areas 11. The transmission mechanism 8 is configured to transmit cryopreservation boxes along its length direction, thereby enabling the transmission of cryopreservation boxes within multiple buffer areas 11. This allows for the transfer of cryopreservation boxes between different storage facilities 1, achieving coordinated storage of multiple storage facilities 1. This facilitates the transfer of samples from one storage facility 1 to another, making the application more convenient.

[0038] Specifically, the transfer mechanism 8 includes a container stage that moves along a linear structural direction and a drive mechanism that drives the container stage to move along the linear structural direction. The container stage can fixably support the cryopreservation boxes. The structure of the drive mechanism can adopt a conventional structure in this field, and its structure will not be described in detail here.

[0039] Preferably, please continue reading. Figure 1Each storage unit 1 is equipped with a storage rack 4, a cryopreservation area transfer robot 5, a first conveying mechanism 6, and a second conveying mechanism 7. The storage rack 4 is located in the storage area 12 and is used to store cryopreservation boxes. The cryopreservation area transfer robot 5 and the first conveying mechanism 6 are located in the storage area 12. The first conveying mechanism 6 is configured to transfer cryopreservation boxes between the storage area 12 and the buffer area 11. Specifically, the first conveying mechanism 6 can dock with the cryopreservation area transfer robot 5 to transfer cryopreservation boxes, and the first conveying mechanism 6 can also dock with the transmission mechanism 8 to transfer cryopreservation boxes. The cryopreservation area transfer robot 5 is configured to transfer cryopreservation boxes between the storage rack 4 and the first conveying mechanism 6. The second conveying mechanism 7 is configured to transfer cryopreservation boxes between the buffer area 11 and the outside. Specifically, the second conveying mechanism 7 can dock with the transmission mechanism 8 to transfer cryopreservation boxes, and the second conveying mechanism 7 can also extend out of the storage unit through an inlet / outlet to transfer cryopreservation boxes.

[0040] Specifically, the first conveying mechanism 6 is a first linear conveying mechanism with a container platform, which can drive the container platform to move in a straight line; the second conveying mechanism 7 is a second linear conveying mechanism with a shovel mechanism, which can drive the shovel mechanism to move in a straight line, and the shovel mechanism can rotate to receive and transfer cryopreservation boxes. The structures of the linear conveying mechanism and the shovel mechanism can adopt conventional structures in this field, and their structures will not be described in detail here.

[0041] Preferably, the biological sample storage system of the present invention further includes at least one tube-picking device 3, which is disposed within the buffer area 11 of one of the cryopreservation containers 1. More preferably, the tube-picking device 3 is disposed within the buffer area 11 of one of the cryopreservation containers 1 located at the end of the linear structure, which effectively saves space and facilitates assembly and use. The tube-picking device 3 is used to transfer cryopreservation tubes containing samples from one cryopreservation container to another. The tube-picking device 3 can adopt a conventional structure in the art, and its structure will not be described in detail here.

[0042] Preferably, each storage unit 1 has a barcode scanner in its buffer area 11 to scan cryopreservation boxes and tubes during entry and exit. This barcode scanner can be linked to the first conveying mechanism 6 or the second conveying mechanism 7 to perform the scanning operation during the transfer of cryopreservation boxes, or it can be a standalone device. The barcode scanner can use a conventional structure in the art, and its structure will not be described in detail here. Alternatively, a single barcode scanner can be provided, linked to the transmission mechanism 8 to perform the scanning operation during transmission, and one scanner can serve multiple storage units 1 simultaneously, effectively saving costs.

[0043] In addition, the biological sample storage system of the present invention also includes a controller, which is capable of executing the storage control method of the biological sample storage system of the present invention.

[0044] Secondly, based on the structure of the above-mentioned biological sample storage system, the present invention also provides a storage control method for a biological sample storage system, which can automatically determine whether to execute a single-zone storage mode or a partitioned storage mode when storing a sample to be stored, so as to successfully store the sample to be stored, ensure sample safety, and reduce sample storage risks.

[0045] Specifically, please refer to Figure 2 The storage control method of the present invention includes the following steps:

[0046] S1: Obtain sample storage instructions.

[0047] Specifically, the user inputs a sample storage command through a display device or a control terminal (e.g., a mobile app or computer) connected to the controller, and the controller can obtain the sample storage command. The sample storage command includes, but is not limited to, instructions for storing biological samples, the number of samples to be stored, the corresponding storage repository, and the target storage location.

[0048] S2: Receive the source cryopreservation box containing the sample to be stored.

[0049] Specifically, the electric gate is opened to connect the buffer area of ​​the storage unit with the pipe-picking device to the external environment, and the second conveying mechanism extends to receive the source cryopreservation box and inputs the source cryopreservation box into the buffer area of ​​the storage unit.

[0050] S3: Based on the sample storage instruction, determine the storage type corresponding to this storage operation.

[0051] Based on the relevant information in the sample storage instruction, determine the storage type corresponding to this storage operation in order to further determine the storage mode to be executed subsequently.

[0052] S4: Based on storage type, selectively execute single-zone storage mode or partitioned storage mode.

[0053] S5: In cases where the storage type cannot be determined, obtain the total number of samples to be stored and the sample information for each sample to be stored.

[0054] Specifically, by scanning the source cryopreservation box and the cryopreservation tubes on the source cryopreservation box, the total number of samples to be stored and the sample information of each sample to be stored are obtained.

[0055] S6: Based on the total number of samples to be stored and the sample information of each sample to be stored, selectively execute single-area storage mode or partitioned storage mode.

[0056] The single-zone storage mode stores all samples to be stored in the same source cryopreservation box into the same repository; the partitioned storage mode stores multiple samples to be stored in the same source cryopreservation box into at least two repositories.

[0057] The storage control method of the present invention can input multiple samples to be stored into the storage repository through the same source cryopreservation box, and then enable the biological sample storage system to intelligently determine whether to execute single-zone storage mode or partitioned storage mode, and then automatically perform storage; even if multiple samples need to be stored in different storage repositories, there is no need to manually allocate the samples to be stored in advance, thereby saving time and improving storage efficiency.

[0058] Preferably, please refer to the following: Figure 3 Step S3, "Based on the sample storage instruction, determine the storage type corresponding to this storage operation," specifically includes:

[0059] S31: Based on the sample storage instruction, determine the total number of samples to be stored in this storage operation and the target storage location of each sample to be stored.

[0060] Based on the relevant information of the sample storage instruction, determine the total number of samples to be stored in this storage operation and the target storage location of each sample to be stored, so as to execute step S32, and determine the storage type corresponding to this storage operation based on the total number of samples to be stored and / or multiple target storage locations.

[0061] Specifically, step S32, "determining the storage type corresponding to this storage operation based on the total number of samples to be stored and / or multiple target storage locations," includes steps S321, S322, S323, S324, and S325.

[0062] S321: Determine whether the total number of samples to be stored is greater than 1.

[0063] Determine whether the total number of samples to be stored is greater than 1. If the result is "no", proceed to step S322; if the result is "yes", proceed to step S323.

[0064] S322: The storage type corresponding to this storage operation is determined to be a single-zone storage type.

[0065] When the total number of samples to be stored is no greater than 1, that is, when there is only one sample to be stored, no partitioning is required, thus determining it as a single-zone storage type and executing the single-zone storage mode.

[0066] S323: Determine whether multiple storage locations are located within the same repository.

[0067] If the total number of samples to be stored is greater than 1, it means that there are at least two samples to be stored. In this case, it is necessary to determine whether multiple storage locations are located in the same repository, so as to more accurately determine the corresponding storage type. Specifically, if the judgment result is "yes", multiple storage locations are located in the same repository, it means that no partitioning is required and the storage type is single-zone storage type, then step S322 is executed; if the judgment result is "no", multiple storage locations are not located in the same repository, it means that partitioning is required and the storage type is partitioned storage type, then step S323 is executed.

[0068] S323: The storage type corresponding to this storage operation is determined to be partitioned storage type.

[0069] Preferably, please continue reading. Figure 3 Step S4, "Selectively execute single-zone storage mode or partitioned storage mode based on storage type", specifically includes: if the storage type is single-zone storage type, then execute step S41; if the storage type is partitioned storage type, then execute step S42.

[0070] S41: Execute single-area storage mode.

[0071] S42: Execute partitioned storage mode.

[0072] Preferably, please refer to the following: Figure 4 Step S6, "Based on the total number of samples to be stored and the sample information of each sample to be stored, selectively execute single-area storage mode or partitioned storage mode," specifically includes:

[0073] S61: Determine whether the total number of samples to be stored is greater than 1.

[0074] Determine whether the total number of samples to be stored is greater than 1. If the result is "no", that is, the total number of samples to be stored is not greater than 1, and thus the total number of samples to be stored is 1, then execute step S41, that is, execute single-area storage mode; if the result is "yes", that is, the total number of samples to be stored is at least two, then execute step S62.

[0075] S62: Based on the sample information of each sample to be stored, determine the number of types of samples to be stored and the number of samples to be stored corresponding to each type.

[0076] Based on the sample information of each sample to be stored, multiple samples to be stored are classified according to their types, thereby determining the number of types of samples to be stored and the number of samples to be stored corresponding to each type. In order to selectively execute single-area storage mode or partitioned storage mode based on the number of types of samples to be stored and the number of samples to be stored corresponding to each type.

[0077] Specifically, the step of "selectively executing single-area storage mode or partitioned storage mode according to the number of types of samples to be stored and the number of samples to be stored corresponding to each type of sample" includes steps S63, S64, S65 and S66.

[0078] S63: Determine whether the number of types of samples to be stored is greater than 1.

[0079] When there are multiple samples to be stored, first determine whether the number of types of samples to be stored is greater than 1. If the result is "no", it means that the multiple samples to be stored belong to the same type. In order to ensure storage security and reduce storage risk, they need to be stored separately and the partitioned storage mode is executed, i.e., step S42 is executed. If the result is "yes", it means that there are at least two types of samples to be stored. Therefore, it is necessary to further determine whether the number of samples to be stored corresponding to each type is greater than 1 in order to further determine whether they need to be stored separately, i.e., step S64 is executed.

[0080] S64: Determine whether the number of samples to be stored for each type is greater than 1.

[0081] In the case of two or more types of samples to be stored, determine whether the number of samples to be stored for each type is greater than 1, and then determine whether partitioned storage is required.

[0082] S65: When the number of samples to be stored for all types is no greater than 1, there is only one sample to be stored for each type. Therefore, multiple samples to be stored for different types do not need to be separated. Execute step S41 to execute single-area storage mode.

[0083] S66: When the number of samples to be stored for any type is greater than 1, and there are two or more samples of at least one type, in order to ensure storage security and reduce storage risk, they need to be stored separately, and the partitioned storage mode is executed, i.e., step S42 is executed.

[0084] S41: Execute single-area storage mode.

[0085] S42: Execute partitioned storage mode.

[0086] The above-mentioned judgment method enables the biological sample storage system to automatically determine the storage mode to be executed during storage operations. The judgment process is simple and the judgment results are accurate, which can save time, improve storage efficiency, and at the same time ensure the security of sample storage and reduce sample storage risks.

[0087] It should be noted that this invention does not impose any restrictions on the specific execution steps of the single-zone storage mode. As long as all samples to be stored in the source cryopreservation box are stored in the same storage repository, it is acceptable. In practical applications, those skilled in the art can set the specific execution steps of the single-zone storage mode according to actual needs. For example, all samples to be stored in the source cryopreservation box can be transferred to a target cryopreservation box in a target storage repository; alternatively, the source cryopreservation box can be directly swapped with a target cryopreservation box in the target storage repository to save transfer time; and so on. Adjustments and changes to the specific execution steps of the single-zone storage mode do not deviate from the basic principles of this invention and should be limited to the scope of protection of this invention.

[0088] In one embodiment, when the storage type can be determined, step S41 "execute single-area storage mode" specifically includes:

[0089] S411: Move the source cryopreservation box to the tube picking station.

[0090] S412: Based on each target storage location, determine the target cryopreservation box corresponding to each sample to be stored.

[0091] S413: Move the target cryopreservation box to the tube picking station.

[0092] S414: Move the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box.

[0093] S415: After scanning the code, return the target cryopreservation box to its original storage location.

[0094] After picking the tubes, scanning the barcode allows you to bind the target cryopreservation box to the sample to be stored. This also facilitates information management by the biosample storage system, enabling real-time recording and correction of new storage information.

[0095] In another embodiment, when the storage type cannot be determined, step S41 "execute single-area storage mode" specifically includes:

[0096] S4101: Move the source cryopreservation box to the tube picking station.

[0097] S4102: Obtain available storage information for each repository.

[0098] S4103: Based on the available storage information of each repository, determine the target repository and target cryopreservation box for the sample to be stored.

[0099] Specifically, the repository with the most free space is selected for storage, or the repository with free space that is closest to the repository with the pipe-picking equipment is selected for storage.

[0100] S4104: Remove the target cryopreservation box from the target storage area and move it to the pipe picking station.

[0101] S4105: Move the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box.

[0102] S4106: After scanning the code, return the target cryopreservation box to its original storage location in the target storage repository.

[0103] After picking the tubes, scanning the barcode allows you to bind the target cryopreservation box to the sample to be stored. This also facilitates information management by the biosample storage system, enabling real-time recording and correction of new storage information.

[0104] It should be noted that the present invention does not impose any restrictions on the specific execution steps of the partitioned storage mode. As long as the multiple samples to be stored in the source cryopreservation box are stored in different storage repositories, those skilled in the art can set the specific execution steps of the partitioned storage mode according to actual needs in practical applications.

[0105] In one embodiment, when the storage type can be determined, step S42 "Execute partitioned storage mode" specifically includes:

[0106] S421: Move the source cryopreservation box to the tube picking station.

[0107] S422: Based on each target storage location, determine the target cryopreservation box corresponding to each sample to be stored.

[0108] S423: Determine the picking order for each target cryopreservation box based on the distance between the storage facility where each target cryopreservation box is located and the picking station.

[0109] S424: Move each target cryopreservation box to the picking station in sequence according to the picking order.

[0110] S425: Move the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box.

[0111] S426: After scanning the code, return the target cryopreservation box to its original storage location.

[0112] After picking the tubes, scanning the barcode allows you to bind the target cryopreservation box to the sample to be stored. This also facilitates information management by the biosample storage system, enabling real-time recording and correction of new storage information.

[0113] In another embodiment, when the storage type cannot be determined, step S42 "Execute partitioned storage mode" specifically includes:

[0114] S4201: Move the source cryopreservation box to the tube picking station.

[0115] S4202: Based on the available storage information of each repository, determine the target repository and target cryopreservation box corresponding to each sample to be stored.

[0116] Specifically, the repository with the most free space is selected for storage, or the repository with free space that is closest to the repository with the pipe-picking equipment is selected for storage.

[0117] S4203: Determine the picking order for each target cryogenic box based on the distance relationship between each target storage unit and the picking station.

[0118] S4204: Move each target cryopreservation box to the picking station in sequence according to the picking order.

[0119] S4205: Move the sample to be stored from the source cryopreservation box to its corresponding target cryopreservation box.

[0120] S4206: After scanning the code, return the target cryopreservation box to its original storage location in the corresponding target repository.

[0121] After picking the tubes, scanning the barcode allows you to bind the target cryopreservation box to the sample to be stored. This also facilitates information management by the biosample storage system, enabling real-time recording and correction of new storage information.

[0122] The technical solution of the present invention has been described above with reference to the preferred embodiments shown in the accompanying drawings. However, it will be readily understood by those skilled in the art that the scope of protection of the present invention is obviously not limited to these specific embodiments. Without departing from the principles of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after such changes or substitutions will all fall within the scope of protection of the present invention.

Claims

1. A storage control method for a biological sample storage system, characterized in that, The biological sample storage system includes multiple storage bins, which are distributed at intervals along a linear structure. Adjacent storage bins are sealed and connected by a connecting channel and can transfer cryopreservation boxes to each other. The storage control method includes: Obtain sample storage instructions; Receive the source cryopreservation box containing the sample to be stored; Based on the sample storage instruction, determine the storage type corresponding to this storage operation; Based on the storage type, either single-zone storage mode or partitioned storage mode may be selectively executed. In cases where the storage type cannot be determined, the total number of samples to be stored and the sample information of each sample to be stored are obtained. Based on the total number of samples to be stored and the sample information of each sample to be stored, the single-area storage mode or the partitioned storage mode is selectively executed. The single-zone storage mode stores all samples to be stored in the same source cryopreservation box into the same storage repository; the partitioned storage mode stores multiple samples to be stored in the same source cryopreservation box into at least two storage repositories.

2. The storage control method for the biological sample storage system according to claim 1, characterized in that, The step of "determining the storage type corresponding to this storage operation based on the sample storage instruction" specifically includes: Based on the sample storage instruction, determine the total number of samples to be stored in this storage operation and the target storage location of each sample to be stored; Based on the total number of samples to be stored and / or multiple target storage locations, determine the storage type corresponding to this storage operation.

3. The storage control method for the biological sample storage system according to claim 2, characterized in that, The step of "determining the storage type corresponding to this storage operation based on the total number of samples to be stored and / or multiple target storage locations" specifically includes: Determine whether the total number of samples to be stored is greater than 1; If the judgment result is "no", then the storage type corresponding to this storage operation is determined to be a single-zone storage type; If the determination result is "yes", then it is determined whether the multiple storage locations are located in the same repository. If the multiple storage locations are located in the same repository, the storage type corresponding to this storage operation is determined to be a single-zone storage type; if the multiple storage locations are not located in the same repository, the storage type corresponding to this storage operation is determined to be a partitioned storage type.

4. The storage control method for the biological sample storage system according to claim 1, characterized in that, The step of "selectively executing single-area storage mode or partitioned storage mode based on the storage type" specifically includes: If the storage type is a single-zone storage type, then the single-zone storage mode is executed; If the storage type is a partitioned storage type, then the partitioned storage mode is executed.

5. The storage control method for the biological sample storage system according to claim 1, characterized in that, The step of "selectively executing the single-area storage mode or the partitioned storage mode based on the total number of samples to be stored and the sample information of each sample to be stored" specifically includes: Determine whether the total number of samples to be stored is greater than 1; If the total number of samples to be stored is not greater than 1, then the single-zone storage mode is executed; If the total number of samples to be stored is greater than 1, then based on the sample information of each sample to be stored, the number of types of samples to be stored and the number of samples to be stored corresponding to each type are determined, and based on the number of types of samples to be stored and the number of samples to be stored corresponding to each type, the single-area storage mode or the partitioned storage mode is selectively executed.

6. The storage control method for the biological sample storage system according to claim 5, characterized in that, The step of "selectively executing the single-area storage mode or the partitioned storage mode according to the number of types of samples to be stored and the number of samples to be stored for each type" specifically includes: Determine whether the number of types of the sample to be stored is greater than 1; If the judgment result is "yes", then determine whether the number of samples to be stored corresponding to each type is greater than 1. Based on the judgment result of whether the number of samples to be stored corresponding to each type is greater than 1, selectively execute the single-area storage mode or the partitioned storage mode. If the result is "no", then the partitioned storage mode is executed.

7. The storage control method for the biological sample storage system according to claim 6, characterized in that, The step of "selectively executing the single-area storage mode or the partitioned storage mode based on the determination result of whether the number of samples to be stored corresponding to each type is greater than 1" specifically includes: If the number of samples to be stored for all types is not greater than 1, then the single-zone storage mode is executed. If the number of samples to be stored for any type is greater than 1, then the partitioned storage mode is executed.

8. The storage control method for a biological sample storage system according to any one of claims 1 to 7, characterized in that, When the storage type can be determined, the step of "executing the single-area storage mode" specifically includes: Move the source cryopreservation box to the tube picking station; Based on each target storage location, determine the target cryopreservation box corresponding to each sample to be stored; Move the target cryopreservation box to the tube picking station; The sample to be stored is moved from the source cryopreservation box to its corresponding target cryopreservation box; After scanning the code, the target cryopreservation box will be returned to its original storage location; And / or, When the storage type can be determined, the step of "executing the partitioned storage mode" specifically includes: Move the source cryopreservation box to the tube picking station; Based on each of the target storage locations, determine the target cryopreservation box corresponding to each of the samples to be stored; Based on the distance relationship between the storage warehouse where each target cryopreservation box is located and the tube picking station, the tube picking order of each target cryopreservation box is determined; Each target cryopreservation box is moved to the tube picking station in sequence according to the tube picking order. The sample to be stored is moved from the source cryopreservation box to its corresponding target cryopreservation box; After scanning the code, the target cryopreservation box is returned to its original storage location.

9. The storage control method for a biological sample storage system according to any one of claims 1 to 7, characterized in that, In cases where the storage type cannot be determined, the step of "executing the single-area storage mode" specifically includes: Move the source cryopreservation box to the tube picking station; Obtain the available storage information for each of the aforementioned repositories; Based on the available storage information of each of the repositories, the target repository and target cryopreservation box for the sample to be stored are determined. The target cryopreservation box is removed from the target storage container and moved to the pipe picking station; The sample to be stored is moved from the source cryopreservation box to its corresponding target cryopreservation box; After scanning the code, the target cryopreservation box will be returned to its original storage location within the target storage repository; And / or, In cases where the storage type cannot be determined, the step of "executing the partitioned storage mode" specifically includes: Move the source cryopreservation box to the tube picking station; Obtain the available storage information for each of the aforementioned repositories; Based on the available storage information of each of the repositories, the target repository and target cryopreservation box corresponding to each of the samples to be stored are determined respectively; Based on the distance relationship between each target storage unit and the tube picking station, the tube picking order of each target cryopreservation box is determined; Each target cryopreservation box is moved to the tube picking station in sequence according to the tube picking order. The sample to be stored is moved from the source cryopreservation box to its corresponding target cryopreservation box; After scanning the code, the target cryopreservation box is returned to its original storage location in the corresponding target repository.

10. A biological sample storage system, comprising a controller, characterized in that, The controller is configured to perform the storage control method for the biological sample storage system as described in any one of claims 1 to 9.

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