A traditional Chinese medicine composition and application thereof

Abstract

This invention belongs to the field of traditional Chinese medicine technology and provides a traditional Chinese medicine composition and its application. The composition consists of Artemisia argyi, Platycladus orientalis leaves, Cuscuta chinensis, Schizonepeta tenuifolia, Saposhnikovia divaricata, Chrysanthemum morifolium, Mentha haplocalyx, Vitex trifolia, and Ligusticum striatum. This formula has the effects of dispelling dampness and promoting hair growth. Artemisia argyi and Platycladus orientalis are the principal herbs, which are aromatic and can clear heat and dampness, remove oil and promote hair growth. Schizonepeta tenuifolia and Saposhnikovia divaricata relieve exterior wind, dispel dampness and eliminate sores. Chrysanthemum morifolium dispels wind and clears heat. When combined with Cuscuta chinensis, the four herbs harmonize the liver and spleen, and are aromatic and clear heat. These are the assistant herbs. Mentha haplocalyx is pungent and cool and dispersing, while Vitex trifolia is bitter and pungent and ascending. These two herbs disperse wind-heat, clear the head and eyes, and are aromatic and expel pathogens. These are the adjuvant herbs. Ligusticum striatum is pungent and warm and ascending. It can dispel wind and dampness, and can also guide the other herbs to the top of the head and scalp. It is a wind-dispelling herb that guides the herbs to the meridians and is aromatic and light. This is the guiding herb. Overall, the formula combines aromatic ingredients, balances cold and warm properties, harmonizes the liver and spleen, and promotes the smooth flow of qi and blood. The combined effects of the various herbs clear heat and dampness, remove excess oil, and promote hair growth.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine technology, and in particular relates to a traditional Chinese medicine composition and its application. Background Technology

[0002] Androgenetic alopecia is a common chronic and disfiguring hair loss disease in dermatology, often referred to as male pattern baldness. It is often accompanied by increased scalp oil and can begin to appear during puberty. It was previously also known as seborrheic alopecia or premature baldness. Clinically, it is characterized by a receding hairline in men, presenting an M-shape, and / or progressive reduction and thinning of hair on the top of the head, known as male pattern baldness. In women, it is characterized by diffuse and progressive thinning and thinning of hair in the frontal and parietal lobes, generally without a receding hairline, known as female pattern baldness.

[0003] Currently, modern medicine treats androgenetic alopecia primarily through the following approaches: anti-androgen therapy, promoting vasodilation, anti-inflammation, antifungal therapy, and regulating the hair growth cycle. Specific treatments include drug therapy, laser therapy, platelet concentrate therapy, and hair transplantation surgery. Among these, the main topical drug is minoxidil, which stimulates the differentiation and proliferation of hair follicle epithelial cells, causing the hair follicle to transition from the resting phase to the anagen phase, promoting the opening of potassium ion channels, and enhancing local blood supply. However, the average onset time for topical minoxidil is 12 weeks, and adverse reactions mainly include hirsutism, scalp irritation, and allergic dermatitis. Furthermore, patients may experience relapse 3-4 months after discontinuing the medication. While all these treatments can improve the symptoms of androgenetic alopecia to some extent, they also easily cause adverse reactions such as male sexual dysfunction, female menstrual abnormalities, scalp irritation, and hirsutism.

[0004] Existing medications are inadequate in terms of efficacy, cost, side effects, and patient tolerance. Traditional Chinese medicine (TCM) external therapies for skin diseases have a long history and rich experience, with abundant and detailed records of TCM external treatments for androgenetic alopecia. Studies indicate that direct application of TCM to the scalp, i.e., transdermal drug delivery, can reduce the adverse reactions of oral medications and improve patient compliance. Furthermore, guided by TCM theory, external application of TCM to the scalp can dredge the meridians, promote blood circulation, and regulate local Qi and blood flow. Summary of the Invention

[0005] This invention provides a traditional Chinese medicine composition and its application, aiming to solve the above-mentioned technical problems.

[0006] The present invention is achieved by providing a traditional Chinese medicine composition, which comprises the following components by weight percentage: 5-25% Artemisia argyi, 5-25% Platycladus orientalis, 5-20% Cuscuta chinensis, 5-20% Schizonepeta tenuifolia, 5-20% Saposhnikovia divaricata, 5-20% Chrysanthemum morifolium, 5-15% Mentha haplocalyx, 5-15% Vitex trifolia, and 5-10% Ligusticum striatum.

[0007] Furthermore, the traditional Chinese medicine composition comprises the following components by weight percentage: 15-20% Artemisia argyi, 15-20% Platycladus orientalis, 10-15% Cuscuta chinensis, 10-15% Schizonepeta tenuifolia, 10-15% Saposhnikovia divaricata, 10-15% Chrysanthemum morifolium, 5-10% Mentha haplocalyx, 5-10% Vitex trifolia, and 5-10% Ligusticum striatum.

[0008] The present invention also provides a method for preparing the above-mentioned traditional Chinese medicine composition, the method comprising the following steps: weighing and mixing the medicinal materials according to the formula, adding 6 to 8 times the total weight of the medicinal materials to soak, decoct, and filter; adding 6 to 8 times the amount of water to the residue of the medicinal materials again to decoct and filter; combining the filtrates from the two filtrations, and concentrating the filtrate to obtain the traditional Chinese medicine composition.

[0009] The present invention also provides the application of the above-mentioned traditional Chinese medicine composition in the preparation of a medicine for treating hair loss.

[0010] Furthermore, the dosage forms of the drug include lotions, ointments, film-forming agents, and aerosols.

[0011] The present invention also provides the application of the above-mentioned traditional Chinese medicine composition in the preparation of cosmetics for preventing hair loss and promoting hair growth.

[0012] The present invention also provides a cosmetic for preventing hair loss and promoting hair growth, wherein the cosmetic for preventing hair loss and promoting hair growth includes the above-mentioned traditional Chinese medicine composition.

[0013] Furthermore, the weight percentage of the traditional Chinese medicine composition in the cosmetic is 0.05% to 20%.

[0014] Furthermore, the herbal composition constitutes 0.1% to 10% by weight in the cosmetic product.

[0015] Furthermore, the cosmetics include any one of shampoo, conditioner, hair mask, hair oil, and hair spray.

[0016] The traditional Chinese medicine composition provided by this invention consists of Artemisia argyi, Platycladus orientalis leaves, Cuscuta chinensis, Schizonepeta tenuifolia, Saposhnikovia divaricata, Chrysanthemum morifolium, Mentha haplocalyx, Vitex trifolia, and Ligusticum striatum. This formula has the effects of dispelling dampness and promoting hair growth. Artemisia argyi is pungent and bitter in taste, warm in nature, and enters the liver, spleen, and kidney meridians. It can dispel cold and relieve pain, and can dispel dampness and relieve itching when used externally. Platycladus orientalis leaves are bitter, astringent, and slightly pungent in taste, cold in nature, and have the effects of cooling blood and stopping bleeding, promoting hair growth and darkening hair. Artemisia argyi and Platycladus orientalis leaves are the principal herbs, which are aromatic and can clear heat and dispel dampness, and promote hair growth. Cuscuta chinensis is pungent and sweet in taste, neutral in nature, and enters the liver, kidney, and spleen meridians. It can tonify the kidney and replenish essence, nourish the liver and improve eyesight, and can dispel wind and remove spots when used externally. Schizonepeta tenuifolia and Saposhnikovia divaricata release the exterior and dispel wind, eliminate dampness and eliminate sores, while Chrysanthemum morifolium dispels wind and clears heat. When combined with Cuscuta chinensis, the four herbs harmonize the liver and spleen, and clear heat with their aromatic properties, thus serving as the assistant herbs. Peppermint, pungent and cooling, ascends and disperses; Vitex trifolia, bitter and pungent, ascends and floats. These two herbs disperse wind-heat, clear the head and eyes, and expel pathogens with their fragrance; they are the adjuvant herbs. Ligusticum striatum, pungent and warm, ascends and disperses wind and dampness, and also guides the other herbs to the top of the head and scalp. As a wind-dispelling herb, it guides the flow of qi and blood, and its fragrance is light and refreshing; it is the guiding herb. Overall, the formula is a harmonious blend of aromatics, combining cold and warm properties, regulating the liver and spleen, and promoting the smooth flow of qi and blood. The combined effects of these herbs clear heat and dampness, reduce oiliness, and promote hair growth. Shampoo containing this herbal composition, applied externally to the scalp, can be absorbed through the skin, and some can enter the bloodstream to exert its therapeutic effects. Furthermore, the aromatic substances volatilized from the shampoo can also enter the brain or lungs through inhalation, exerting a therapeutic effect. Detailed Implementation

[0017] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below through embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the invention.

[0018] Example 1

[0019] This invention provides a traditional Chinese medicine composition comprising the following components: 200g of Artemisia argyi, 150g of Platycladus orientalis, 150g of Cuscuta chinensis, 100g of Schizonepeta tenuifolia, 100g of Saposhnikovia divaricata, 100g of Chrysanthemum morifolium, 100g of Mentha haplocalyx, 50g of Vitex trifolia, and 50g of Ligusticum striatum.

[0020] The preparation method of the above-mentioned traditional Chinese medicine composition includes the following steps:

[0021] Weigh the medicinal materials according to the above formula, mix the medicinal materials and add 8000ml of water to decoct for 1 hour, filter and collect the filtrate; add 6000ml of water to the residue and decoct for 30 minutes, filter and collect the filtrate, combine the two filtrates and pass through a 140-mesh sieve, cool to room temperature to obtain the Chinese medicine filtrate, concentrate the Chinese medicine filtrate to make an extract of the Chinese medicine composition with a relative density of 1.25 (60℃).

[0022] Example 2

[0023] This invention provides a traditional Chinese medicine composition comprising the following components: 150g of Artemisia argyi, 200g of Platycladus orientalis, 100g of Cuscuta chinensis, 150g of Schizonepeta tenuifolia, 100g of Saposhnikovia divaricata, 100g of Chrysanthemum morifolium, 50g of Mentha haplocalyx, 100g of Vitex trifolia, and 50g of Ligusticum striatum.

[0024] The preparation method of the above-mentioned traditional Chinese medicine composition is the same as that in Example 1.

[0025] Example 3

[0026] This invention provides a traditional Chinese medicine composition comprising the following components: 250g of Artemisia argyi, 200g of Platycladus orientalis, 100g of Cuscuta chinensis, 100g of Schizonepeta tenuifolia, 100g of Saposhnikovia divaricata, 100g of Chrysanthemum morifolium, 50g of Mentha haplocalyx, 50g of Vitex trifolia, and 50g of Ligusticum striatum.

[0027] The preparation method of the above-mentioned traditional Chinese medicine composition is the same as that in Example 1.

[0028] Example 4

[0029] This invention provides a traditional Chinese medicine composition comprising the following components: 150g of Artemisia argyi, 150g of Platycladus orientalis, 100g of Cuscuta chinensis, 100g of Schizonepeta tenuifolia, 150g of Saposhnikovia divaricata, 150g of Chrysanthemum morifolium, 50g of Mentha haplocalyx, 50g of Vitex trifolia, and 100g of Ligusticum striatum.

[0030] The preparation method of the above-mentioned traditional Chinese medicine composition is the same as that in Example 1.

[0031] Application Examples

[0032] This invention provides a shampoo for preventing hair loss and promoting hair growth containing the traditional Chinese medicine composition prepared in Example 1. The shampoo comprises: 200 ml of the extract of the traditional Chinese medicine composition prepared in Example 1, 90 g of sodium fatty alcohol polyoxyethylene ether sulfate, 30 g of coconut oil fatty acid diethanolamide, 20 ml of glycerol, 0.4 g of ethylparaben, and an appropriate amount of hydrated citric acid.

[0033] The preparation method of the above shampoo includes the following steps:

[0034] Take 90g of sodium fatty alcohol polyoxyethylene ether sulfate and 30g of coconut oil fatty acid diethanolamide, heat them separately to 85-90℃ to melt, mix them, and stir evenly. After cooling to 60℃, add 200ml of extract and stir evenly. After cooling to 45℃, add 20ml of glycerol and 0.4g of ethylparaben in sequence, heat to boiling, maintain boiling for 30s, and then cool to 45℃. Add hydrated citric acid to adjust the pH value to 5.0-6.0 to obtain a shampoo that prevents hair loss and promotes hair growth.

[0035] Experimental Methods: Fifty-seven patients with androgenetic alopecia due to damp-heat syndrome who visited the Dermatology Clinic of the Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine were selected. Based on the order of enrollment, these 57 patients were randomly divided into a treatment group (n=28) and a control group (n=29). The treatment group received the shampoo prepared according to the application examples of this invention, used twice a week, 5-10 ml / time, with the drug remaining on the scalp for 3-5 minutes each time. The control group received 2% ketoconazole shampoo (Cecilin) ​​(Ailein Biotechnology (Shanghai) Co., Ltd., Product Approval Number: H20000588, Specification: 2% 50ml*1 bottle / box), used twice a week, 5-10 ml / time, with the drug remaining on the scalp for 3-5 minutes each time. Both groups received continuous treatment for 12 weeks. During treatment, patients maintained regular diet and rest, kept a positive mood, controlled hair loss triggers, and avoided other hair loss medications and hair growth cosmetics.

[0036] Observation indicators: Clinical symptom scores and points. The clinical symptom scores primarily reflect Traditional Chinese Medicine (TCM) syndrome differentiation. Hair loss scoring criteria: 0 points for <100 hairs / day, 2 points for 100-150 hairs / day, 4 points for 150-200 hairs / day, and 6 points for >200 hairs / day. Itching severity was assessed using a visual analogue scale for pain. The VAS scale (scale) is used to quantify itch. 0 points indicates no itching, and 10 points indicates the extreme degree of itching. The oiliness rating is as follows: 0 points indicates no oiliness, with an interval of more than 3 days between washes; 2 points indicates mild oiliness, with an interval of 2 days between washes; 4 points indicates moderate oiliness, with an interval of 1 day between washes; 6 points indicates severe oiliness, with an oily feeling even after 1 day between washes. The scaling rating is as follows: 0 points indicates no scaling; 2 points indicates a small amount of scaling; 4 points indicates a large amount of scaling; 6 points indicates a large amount of scaling. New hair growth is defined as follows: 0 points indicates all new hair has grown normally; 2 points indicates more than 2 / 3 of new hair has grown, with uneven hair color and thickness; 4 points indicates 1 / 3 of new hair has grown, with yellowish and fine hair; 6 points indicates no new hair growth or only a small amount of vellus hair.

[0037] Clinical efficacy evaluation criteria: formulated with reference to the "Guiding Principles for Clinical Research of New Traditional Chinese Medicines (Trial Implementation)", the Nimodipine scoring method is used to calculate the clinical efficacy level with quantitative scores: Efficacy index (X) = (Pre-treatment clinical symptom score - Post-treatment clinical symptom score) / Pre-treatment clinical symptom score × 100%, Total effective rate = Basic cure rate + Significant effect rate + Effective rate, see Table 1.

[0038] Table 1. Criteria for Judging Clinical Efficacy

[0039] Basically cured New hair growth in the balding area is normal, with no itching, oiliness, or scaling; score is 0. ≥95％ Effective Itching, oiliness, and dandruff have significantly improved, and more new hair has grown. 95％＞X≥70％ efficient Itching, oiliness, and dandruff have improved, and a small amount of new hair has grown. 70％＞X≥30％ invalid Hair loss is still significant or no new hair growth is observed, or only a small amount of vellus hair is growing. ＜30％

[0040] Dermatology Life Quality Score: Patients' quality of life was assessed before treatment and 12 weeks after treatment using the Dermatology Life Quality Index (DLQI) as the quantitative assessment standard. The DLQI includes 10 items such as frustration or embarrassment, pain, and itching. It is assessed using a 4-point scoring system (0-3 points), with a score range of 0-30 points. The lower the score, the better the quality of life.

[0041] Hair microscopic evaluation: Using the FotoFinderbodystudio ATBM digital dermatoscope (manufacturer: FotoFinder Systems GmbH, model: FotoFinderbodystudio ATBM), macroscopic images were acquired in panoramic mode and microscopic mode, centered on the left temple, Baihui acupoint (intersection of the midline of the head and the line connecting the tips of both ears), and hair whorl. A 20x magnification microscope and a polarized light source were used to collect and record the number of hairs, hair diameter variation rate, yellow spot sign, brown follicular pilaris sign, and degree of scalp inflammation before and after treatment. The evaluation method for scalp inflammation was as follows: 0 points for normal skin color, 2 points for scattered redness and a small amount of telangiectasia, 4 points for moderate redness and moderate telangiectasia, and 6 points for diffuse redness and significant telangiectasia.

[0042] Statistical analysis: Data conforming to a normal distribution are expressed as mean ± standard deviation (x ± s). Paired t-tests are used to compare means before and after treatment within the same group, and independent samples t-tests are used to compare means between two groups. Data not fully conforming to a normal distribution are expressed as M(P25, P75). Wilcoxon test is used to compare medians before and after treatment within the same group, and Mann-Whitney U test is used to compare the distributions of two groups. Chi-square test is used for nominal categorical variables, and Mann-Whitney U test is used for ordinal variables. P < 0.05 indicates statistical significance.

[0043] result

[0044] Comparison of clinical symptom scores and clinical efficacy: Before treatment, the clinical symptom scores and scores of the two groups were compared, and there were no statistically significant differences (P>0.05), as detailed in Table 2. After treatment, the clinical symptom scores and scores of both groups decreased compared with before treatment (P<0.05). The treatment group showed better hair regrowth than the control group (P>0.05), while the control group showed better improvement in oiliness than the treatment group (P<0.05). There were no statistically significant differences in hair loss score, itching score, scaling score, and total score between the treatment group and the control group (P>0.05). The clinical effective rate of the treatment group was higher than that of the control group (P<0.05), as detailed in Tables 3-6.

[0045] Table 2 Comparison of clinical symptoms and scores between the two groups before treatment [M(P25, P75)]

[0046] hair loss 0.00(0.00，2.00) 0.00(0.00，2.00) -1.171 0.242 itching 2.00(0.00，2.00) 2.00(0.00，2.00) -0.258 0.796 greasy 2.00(2.00，4.00) 2.00(2.00，4.00) -0.747 0.455 Scales 2.00(2.00，3.50) 2.00(1.00，3.00) -0.193 0.847 New hair 6.00(6.00，6.00) 6.00(6.00，6.00) -1.018 0.309 Total points 12.00(10.50，14.00) 12.00(10.00，14.00) -0.287 0.774

[0047] Table 3 Comparison of clinical symptoms before and after treatment in the treatment group [M(P25, P75)]

[0048] hair loss 0.00(0.00，2.00) 0.00(0.00，0.00) -2.121 0.034 itching 2.00(0.00，2.00) 0.00(0.00，2.00) -2.324 0.020 greasy 2.00(2.00，4.00) 2.00(0.50，2.00) -3.638 0.000 Scales 2.00(2.00，3.50) 2.00(0.00，2.00) -2.828 0.005 New hair 6.00(6.00，6.00) 4.00(4.00，4.00) -4.583 0.000 Total points 12.00(10.50，14.00) 8.00(6.00，10.00) -4.607 0.000

[0049] Table 4. Comparison of clinical symptoms before and after treatment in the control group [M(P25, P75)]

[0050] hair loss 0.00(0.00，2.00) 0.00(0.00，0.00) -2.887 0.004 itching 2.00(2.00，2.00) 0.00(0.00，2.00) -3.317 0.001 greasy 2.00(2.00，4.00) 0.00(0.00，2.00) -3.819 0.000 Scales 2.00(1.00，3.00) 2.00(0.00，2.00) -3.207 0.001 New hair 6.00(6.00，6.00) 6.00(6.00，6.00) -2.449 0.014 Total points 12.00(10.00，14.00) 8.00(6.00，10.00) -4.416 0.000

[0051] Table 5. Comparison of clinical symptoms between groups after treatment [M(P25, P75)]

[0052] Number of hair loss 0.00(0.00，0.00) 0.00(0.00，0.00) -0.303 0.762 itching 0.00(0.00，2.00) 0.00(0.00，2.00) -0.466 0.641 greasy 2.00(0.50，2.00) 0.00(0.00，2.00) -1.989 0.047 Scales 2.00(0.00，2.00) 2.00(0.00，2.00) -0.036 0.971 New hair 4.00(4.00，4.00) 6.00(6.00，6.00) -4.351 0.000 Total points 8.00(6.00，10.00) 8.00(6.00，10.00) -0.745 0.456

[0053] Table 6 Comparison of clinical efficacy between the two groups of patients [n(%)]

[0054] Treatment group 28 0 2 21 5 82.14％ -2.128 0.033 control group 29 0 2 13 14 51.72％ - -

[0055] DLQI score comparison

[0056] Before treatment, there were no statistically significant differences in DLQI scores between the two groups (P > 0.05). After treatment, DLQI scores in both groups decreased compared to before treatment (P < 0.05), and the score in the treatment group was lower than that in the control group (P < 0.05), as detailed in Table 7.

[0057] Table 7 Comparison of DLQI (Degree of Life Quality) scores [M(P25, P75)]

[0058] control group 29 6.00(3.00，14.00) 4.00(3.00，11.00) -4.008 0.000 Treatment group 28 6.00(3.25，13.75) 2.50(1.00，7.75) -4.384 0.000 Z-value - -0.048 -1.967 - - p-value - 0.962 0.049 - -

[0059] Comparison of hair mirror indicators

[0060] Compared with before treatment, the hair diameter variation rate and scalp inflammation were significantly reduced in both groups after treatment (P<0.05), while the yellow spot sign and brown piloerection sign showed no significant improvement (P>0.05). The number of hairs in the treatment group increased significantly after treatment (P<0.05), while the number of hairs in the control group did not show significant improvement (P>0.05). See Tables 8 and 9 for details. After treatment, the hair variation rate and number of hairs at Baihui acupoint and hair whorl were lower in the treatment group than in the control group (P<0.05), while there were no significant differences in other indicators between the two groups (P>0.05). See Tables 10 and 11 for details.

[0061] Table 8. Hair microscopy indicators before and after treatment in the treatment group

[0062]

[0063]

[0064] Table 9. Hair microscopy indicators before and after treatment in the control group.

[0065]

[0066] Table 10. Hair microscopy indicators between treatment groups after treatment

[0067]

[0068]

[0069] Table 11. Trichomicroscopic examination indicators between groups after treatment

[0070]

[0071] The above results show that after treatment, the TCM syndrome elements (number of hair loss, itching, oiliness, scaling), new hair growth, and scores of both groups of patients decreased compared with before treatment (P<0.05). Moreover, the two groups showed comparable efficacy in improving the number of hair loss, itching, scaling, and scores after treatment (P>0.05). The treatment group showed better improvement in new hair growth than the control group (P<0.05), confirming that the shampoo provided in the application examples of this invention has the effects of clearing heat and removing dampness, removing oil and promoting hair growth.

[0072] Comparing trichoscopic images of the two groups of patients before and after 12 weeks of treatment, and analyzing the index data, the results showed that the variation rate of hair diameter and scalp inflammation at the left temple, Baihui acupoint, and hair whorl were lower in both groups than before treatment. The treatment group showed a significant increase in hair quantity (P < 0.05), while the control group showed no significant increase in hair quantity (P > 0.05), confirming that the shampoo provided in this invention has the effect of promoting hair growth and improving scalp inflammation. The traditional Chinese medicine composition provided in this invention, containing Artemisia argyi, Platycladus orientalis, Schizonepeta tenuifolia, Saposhnikovia divaricata, Chrysanthemum morifolium, Mentha haplocalyx, Ligusticum striatum, and Vitex trifolia, has antibacterial, antifungal, or anti-inflammatory properties. It can inhibit Malassezia or Staphylococcus aureus, improve perifollicular inflammation, and alleviate symptoms of androgenetic alopecia. Platycladus orientalis and Cuscuta chinensis can reduce the sensitivity of scalp hair follicles to testosterone, thereby treating androgenetic alopecia.

[0073] The DLQI score was used to evaluate the quality of life of the two groups of patients with androgenetic alopecia. After 12 weeks of medication, the results showed that the DLQI scores of both groups decreased after treatment compared with before treatment. The treatment group showed better improvement in quality of life than the control group (P<0.05). It is inferred that the improvement in quality of life of patients with androgenetic alopecia provided by the application example of this invention may be an indirect effect of symptom improvement.

[0074] In summary, patients with androgenetic alopecia often have phlegm and dampness, which over time transforms into heat, obstructing hair follicles and hindering hair regrowth. Therefore, the treatment of androgenetic alopecia should focus on aromatic qi-regulating, heat-clearing, and dampness-removing effects, requiring the use of large amounts of aromatic drugs. The traditional Chinese medicine compositions provided in this invention are all aromatic drugs, and the reasons why these compositions can treat androgenetic alopecia are as follows:

[0075] Firstly, aromatic herbs are pungent, warm, and drying, possessing the properties of dispersing and penetrating, which can resolve phlegm and dampness and regulate the flow of Qi. Patients with androgenetic alopecia often have a damp-heat constitution. Phlegm and dampness are Yin evils, which are sticky in nature. Aromatic herbs are pungent, warm, and penetrating, reaching the surface, which can not only promote drug absorption but also facilitate the expulsion of damp-heat evils from the surface. Once the evils are eliminated, the hair growth environment is improved, hair regrowth has a source, and symptoms such as oily scalp, dandruff, and hair loss can be relieved.

[0076] Secondly, some aromatic drugs are pungent and cool in nature, and have the function of dispelling wind and clearing heat. Once the wind-heat evil is resolved, it will not hinder hair growth and reduce hair loss.

[0077] Third, aromatic drugs have a pleasant fragrance that can improve mood and, to some extent, alleviate patients' tension and anxiety, thus reducing hair loss.

[0078] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A topical traditional Chinese medicine composition for treating hair loss, characterized in that, The traditional Chinese medicine composition comprises the following components by weight percentage: 15-20% Artemisia argyi, 15-20% Platycladus orientalis, 10-15% Cuscuta chinensis, 10-15% Schizonepeta tenuifolia, 10-15% Saposhnikovia divaricata, 10-15% Chrysanthemum morifolium, 5-10% Mentha haplocalyx, 5-10% Vitex trifolia, and 5-10% Ligusticum striatum.

2. The method for preparing the traditional Chinese medicine composition according to claim 1, characterized in that, The preparation method includes the following steps: weighing and mixing the medicinal materials according to the formula, adding 6-8 times the total weight of the medicinal materials to soak, decoct, and filter; adding 6-8 times the amount of water to the residue of the medicinal materials again to decoct and filter; combining the filtrates from the two filtrations, and concentrating the filtrate to obtain the traditional Chinese medicine composition.

3. The use of the traditional Chinese medicine composition according to claim 1 in the preparation of a medicament for treating hair loss.

4. The application according to claim 3, characterized in that, The dosage form of the drug is a lotion, ointment, film-forming agent, or aerosol.

5. The application of the traditional Chinese medicine composition according to claim 1 in the preparation of cosmetics for preventing hair loss and promoting hair growth.

6. A cosmetic product for preventing hair loss and promoting hair growth, characterized in that, The hair loss prevention and hair growth cosmetics include the traditional Chinese medicine composition described in claim 1.

7. The cosmetic product according to claim 6, characterized in that, The weight percentage of the traditional Chinese medicine composition in the cosmetic is 0.05% to 20%.

8. The cosmetic product according to claim 7, characterized in that, The weight percentage of the traditional Chinese medicine composition in the cosmetic is 0.1% to 10%.

9. The cosmetic product according to claim 6, characterized in that, The cosmetic product is any one of the following: shampoo, conditioner, hair mask, hair oil, and hair spray.

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