An integrated filling equipment for active pharmaceutical ingredients

Abstract

This invention relates to the field of ointment filling technology and discloses an integrated filling device for active pharmaceutical ingredients, including a filling nozzle, a first lifting mechanism, and a feeding mechanism. The first lifting mechanism drives the filling nozzle to move vertically up and down. The feeding mechanism is connected to the inside of the filling nozzle through a pipe. The inside of the filling nozzle is hollow and the bottom can be sealed. A conveying section is installed inside the filling nozzle. The ointment is filled into the packaging bottle from the conveying section. The conveying section can move vertically up and down inside the filling nozzle. After a single filling of ointment, the conveying section retracts into the filling nozzle as the filling nozzle rises and resets. Then the filling nozzle closes, and the conveying section is sealed inside the filling nozzle. This prevents the ointment adhering to the conveying section from falling off and sticking to other packaging bottles, thus avoiding affecting subsequent packaging operations.

Description

Technical Field

[0001] This invention relates to the field of drug filling technology, specifically to an integrated filling device for active pharmaceutical ingredients. Background Technology

[0002] Yao medicine is mainly distributed in the Dayao Mountains. The medicinal materials are mainly herbs and trees. Common medicinal materials include those from the Polygonaceae, Polygonaceae, Rosaceae, Fabaceae, Lamiaceae, Fungiaceae, Cucurbitaceae, Liliaceae, and Orchidaceae families. Ointment-like Yao medicine is a common dosage form in traditional Yao medicine. It is usually made by decocting, refining, mixing and adding appropriate bases (such as animal fat, vegetable oil, beeswax, etc.) of various herbs. Ointment-like medicine is one of the main types of Yao medicine.

[0003] For example, patent CN105174169B, published on January 26, 2018, discloses a filling machine, relating to the field of pharmaceutical equipment technology. It includes: a frame; a filling station mounted on the frame, comprising a rotating chassis, a main rotary wheel, a high-level liquid storage tank, a plunger pump, a filling device, a first lifting device, and a pneumatic angle valve; the plunger pump body is fixed to the rotating chassis, and the piston rod is connected to the first lifting device; the filling device includes a filling nozzle aligned with the mouth of a preparation bottle; the pneumatic angle valve includes an inlet and two outlets, the inlet communicating with the high-level liquid storage tank, one of the two outlets communicating with an opening on the plunger pump body, and the other communicating with the filling nozzle; the first lifting device drives the piston rod to extend, the pneumatic angle valve connects the high-level liquid storage tank to the plunger pump, and the plunger pump draws in the liquid medicine; the first lifting device drives the piston rod... The pneumatic rotary valve connects the plunger pump to the filling nozzle, and the plunger pump delivers the liquid medicine through the filling nozzle into the preparation bottle. A first guide post is provided on the rotating chassis. The piston rod of the plunger pump passes through the first guide post and the rotating chassis along the axial direction of the first guide post and is connected to the first lifting device. The first lifting device includes a first lifting cam mounted on the frame for driving the piston rod to retract and a first reset device positioned between the piston rod and the rotating chassis for driving the piston rod to extend. The piston rod cooperates with the first lifting cam via a first positioning element. Driven by the first lifting device, the piston rod retracts after the preparation bottle enters the filling station and before it leaves the filling station. Driven by the first reset device, the piston rod extends after the preparation bottle leaves the filling station and before it enters the filling station again.

[0004] Existing filling equipment is mostly used for filling liquid medicines with high fluidity. However, when filling ointments, which have poor fluidity and high viscosity, the ointment tends to stick to the nozzle outlet after each filling. This can cause the ointment to fall onto the conveyor or stick to the subsequent packaging bottles, thus affecting subsequent filling operations. Summary of the Invention

[0005] The purpose of this invention is to provide an integrated filling device for active pharmaceutical ingredients (APIs) to address the aforementioned shortcomings of the prior art.

[0006] To achieve the above objectives, the present invention provides the following technical solution: an integrated filling device for raw materials, comprising a filling nozzle, a first lifting mechanism, and a feeding mechanism. The first lifting mechanism is used to drive the filling nozzle to move vertically up and down. The feeding mechanism is connected to the inside of the filling nozzle through a pipe. The inside of the filling nozzle is hollow and the bottom can be sealed. A conveying section is installed inside the filling nozzle. The ointment is filled into the packaging bottle from the conveying section. The conveying section can move vertically up and down inside the filling nozzle.

[0007] Preferably, the filling nozzle, the first lifting mechanism, and the feeding mechanism are all mounted on the frame, and the feeding mechanism is connected to the inner wall of the filling nozzle through a flexible hose.

[0008] Preferably, a conveying mechanism is also installed on the frame, and the packaging bottles are arranged vertically on the conveying mechanism.

[0009] Preferably, the bottom of the filling nozzle is provided with a switching mechanism, which is used to control the opening and closing of the bottom opening of the filling nozzle.

[0010] Preferably, it also includes a second lifting mechanism, which is used to drive the material conveying section to move vertically up and down inside the filling nozzle.

[0011] Preferably, the conveying section includes a piston plate, which is dynamically sealed inside the filling nozzle, and an electrically controlled valve is installed at the center of the piston plate.

[0012] Preferably, it also includes a drive mechanism for driving the filling nozzle to rotate up and down.

[0013] Preferably, the drive mechanism includes a support plate, a drive motor, a fixed plate, a collar, and a connecting rod. The support plate is fixedly installed on the output shaft of the first lifting mechanism. The upper end of the fixed plate is fixedly connected to the support plate. The drive motor is installed on the outer wall of the fixed plate. The collar is fixedly sleeved on the outer wall of the filling nozzle. The output shaft of the drive motor is fixedly connected to the collar through the connecting rod.

[0014] Preferably, the second lifting mechanism includes an electric push rod and a magnetic ring. The filling nozzle includes an inner tube and an outer tube. The outer tube is sleeved outside the inner tube, and a receiving groove is formed between the outer tube and the inner tube. The magnetic ring is located in the receiving groove. A metal block is installed inside the piston plate. The piston plate is magnetically connected to the magnetic ring through the metal block. A protrusion is provided on the outer wall of the magnetic ring. A sliding groove is opened on the outer wall of the outer tube. The protrusion is located in the sliding groove and forms a sliding guide engagement with the sliding groove. The electric push rod is used to drive the protrusion to move along the groove direction of the sliding groove.

[0015] Preferably, the electric push rod is arranged vertically, the fixed end of the electric push rod is fixedly connected to the support plate, the collar is provided with a through hole, the through hole corresponds to and is connected to the slide groove, the axis of the inner tube is collinear with the axis of the outer tube, and the groove direction is consistent with the axis of the outer tube.

[0016] The beneficial effects of the present invention are as follows: In the above technical solution, after a single filling of ointment, the feeding part of the present invention retracts into the filling nozzle while the filling nozzle rises and resets, and then the filling nozzle closes, and the feeding part is sealed inside the filling nozzle, which can prevent the ointment adhering to the feeding part from falling off and sticking to other packaging bottles, thus avoiding affecting subsequent packaging operations. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this invention. For those skilled in the art, other drawings can be obtained based on these drawings.

[0018] Figure 1 This is a schematic diagram of the structure provided for an embodiment of the present invention; Figure 2 Provided for embodiments of the present invention Figure 1 Enlarged view of point A in the image; Figure 3 This is a partial cross-sectional view of the filling nozzle provided in an embodiment of the present invention; Figure 4 This is an axial sectional view of the filling nozzle provided in an embodiment of the present invention; Figure 5 This is a top view of the filling nozzle provided in an embodiment of the present invention.

[0019] Explanation of reference numerals in the attached figures: 1. Filling nozzle; 11. Inner tube; 12. Outer tube; 13. Receiving tank; 15. First chamber; 16. Second chamber; 2. Conveying section; 21. Piston plate; 22. Electrically controlled valve; 3. First lifting mechanism; 4. Feeding mechanism; 5. Conveying mechanism; 6. Switching mechanism; 7. Second lifting mechanism; 71. Electric push rod; 72. Magnetic ring; 73. Protrusion; 8. Drive mechanism; 81. Support plate; 82. Drive motor; 83. Fixing plate; 84. Collar; 85. Connecting rod; 86. Perforation. Detailed Implementation

[0020] To enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0021] In the description of this invention, unless otherwise stated, "a plurality of" means two or more; the terms "upper," "lower," "left," "right," "inner," "outer," "front end," "rear end," "head," and "tail," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed or operated in a specific orientation, and therefore should not be construed as a limitation of this invention. In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "connected" and "linked" should be interpreted broadly. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0022] like Figures 1-5 As shown, this embodiment of the invention provides an integrated filling device for active pharmaceutical ingredients, including a filling nozzle 1, a first lifting mechanism 3, and a feeding mechanism 4. The first lifting mechanism 3 is used to drive the filling nozzle 1 to move vertically up and down. The feeding mechanism 4 is connected to the inside of the filling nozzle 1 through a pipe. The filling nozzle 1 is hollow inside and the bottom can be sealed. A conveying part 2 is installed inside the filling nozzle 1. The ointment is filled into the packaging bottle from the conveying part 2. The conveying part 2 can move vertically up and down inside the filling nozzle 1.

[0023] Specifically, the filling nozzle 1, the first lifting mechanism 3, and the feeding mechanism 4 are all mounted on the frame. The feeding mechanism 4 is connected to the inner wall of the filling nozzle 1 via a pipe, preferably a flexible hose. The feeding mechanism 4 includes at least a container for storing the ointment and a feeding pump, with the feeding pump installed inside the container. This is existing technology and will not be elaborated further. A valve can also be installed at the connection between the flexible hose and the inside of the filling nozzle 1. This valve controls the flow of the ointment from the pipe into the filling nozzle 1. A conveying mechanism 5 is also mounted on the frame, with the packaging bottles arranged vertically on the conveying mechanism 5. The first lifting mechanism 3 can be a linear drive mechanism such as a hydraulic cylinder, pneumatic cylinder, or electric telescopic rod. The filling nozzle 1 has an internally hollow cylindrical structure, and a switching mechanism 6 is provided at the bottom of the filling nozzle 1. Figure 5 As shown, the switching mechanism 6 is preferably an iris switch mechanism. The opening and closing of the filling nozzle 1 is prior art and will not be described in detail. The opening and closing of the bottom opening of the filling nozzle 1 is controlled by the iris switch mechanism 6.

[0024] In this embodiment, a second lifting mechanism 7 is also included. The second lifting mechanism 7 is used to drive the conveying part 2 to move vertically up and down inside the filling nozzle 1. In actual use, the conveying mechanism 5 conveys the packaging bottle to directly below the filling nozzle 1. The first lifting mechanism 3 drives the filling nozzle 1 to descend, so that the lower end of the filling nozzle 1 extends into the packaging bottle. Then, the second lifting mechanism 7 drives the conveying part 2 to descend to the bottom outlet of the filling nozzle 1. During this process, the switching mechanism 6 is opened. At this time, the ointment conveyed to the filling nozzle 1 by the feeding mechanism 4 flows out from the conveying part 2. The ointment is then filled into the packaging bottle. After filling, the second lifting mechanism 7 drives the conveying part 2 to rise first, that is, the conveying part 2 returns to the middle of the filling nozzle 1. Then the switch mechanism 6 at the bottom of the filling nozzle 1 closes, and the first lifting mechanism 3 drives the filling nozzle 1 to rise and extend from inside the packaging bottle. During this process, the bottom opening of the filling nozzle 1 is closed by the switch mechanism 6, which can seal the conveying part 2 inside the filling nozzle 1. This can prevent the ointment adhering to the conveying part 2 from falling off and sticking to other packaging bottles, thus avoiding affecting subsequent filling operations.

[0025] In an optional embodiment, preferably, the feeding section 2 includes a piston plate 21, which is dynamically sealed inside the filling nozzle 1, and an electrically controlled valve 22 is installed at the center of the piston plate 21.

[0026] Specifically, a hole is provided at the center of the piston plate 21, and an electrically controlled valve 22 is installed in the hole. The electrically controlled valve 22 can be a solenoid valve, an electric valve, or a pneumatic valve, etc. All of the above-mentioned electrically controlled valves 22 are existing technologies and will not be described in detail. In this embodiment, the second lifting mechanism 7 can be a linear drive mechanism such as a cylinder or an electric telescopic rod installed inside the filling nozzle 1 and connected to the piston plate 21. When the filling nozzle 1 extends into the packaging bottle and the bottom opening is opened, the second lifting mechanism 7 drives the conveying section 2 to descend to the filling nozzle 1. At the bottom outlet, the electrically controlled valve 22 opens, and the feeding mechanism 4 delivers the ointment into the filling nozzle 1. As the filling nozzle 1 is filled with ointment and the electrically controlled valve 22 opens, the ointment falls from the valve opening of the electrically controlled valve 22 under the continuous delivery of the feeding mechanism 4. Because the opening of the electrically controlled valve 22 is smaller than the opening of the switching mechanism 6, the ointment will fall directly from the electrically controlled valve 22 onto the packaging bottle and will not adhere to the switching mechanism 6 or the bottom opening of the filling nozzle 1 during the falling process.

[0027] In the above embodiment, the problem of ointment falling off is solved by sealing the feeding part 2 into the filling nozzle 1 when the filling nozzle 1 extends. However, the ointment will still adhere to the surface of the feeding part 2, i.e., the piston plate 21, for a long time, causing the ointment in this part to never enter the packaging bottle, resulting in waste and inaccurate filling volume. Therefore, in order to solve the above technical problem, in another embodiment of the present invention, a driving mechanism 8 is further included. The driving mechanism 8 is used to drive the filling nozzle 1 to rotate up and down.

[0028] Specifically, the drive mechanism 8 includes a support plate 81, a drive motor 82, a fixed plate 83, a collar 84, and a connecting rod 85. The support plate 81 is fixedly installed on the output shaft of the first lifting mechanism 3. The upper end of the fixed plate 83 is fixedly connected to the support plate 81. The drive motor 82 is installed on the outer wall of the fixed plate 83. The collar 84 is fixedly sleeved on the outer wall of the filling nozzle 1. The output shaft of the drive motor 82 is fixedly connected to the collar 84 through the connecting rod 85. Since there are multiple sets of filling nozzles 1, and each set of filling nozzles 1 has a collar 84 fixedly sleeved on its outer wall, each set of collars 84 is also connected to each other through the connecting rod 85. The central axis of the connecting rod 85 is collinear with the axis of the output shaft of the drive motor 82, and they are all arranged horizontally. In the initial state, the material conveying part 2, i.e., the piston plate 21, is located in the middle of the filling nozzle 1. The piston plate 21 divides the interior of the filling nozzle 1 into upper and lower sections. The two chambers are designated as the first chamber 15 located below the piston plate 21 and the second chamber 16 located above the piston plate 21. The feeding mechanism 4 is connected to the first chamber 15 and the second chamber 16 inside the filling nozzle 1 through two sets of hoses. Valves are installed at the connection points between the two sets of hoses and the first chamber 15 and the second chamber 16. These valves are one-way valves to prevent the ointment in the first chamber 15 or the second chamber 16 from flowing back into the feeding mechanism 4. In this embodiment, the filling nozzle 1 is a cylindrical structure with openings at both ends. Switching mechanisms 6 are installed at both ends of the filling nozzle 1. The two sets of switching mechanisms 6 are located in the first chamber 15 and the second chamber 16, respectively. The side of the piston plate 21 that is close to or located in the first chamber 15 is designated as the first side, and the corresponding other side is designated as the second side. In actual use, the filling of the ointment includes multiple sequential cycles of the first and second strokes. In the first stroke, the second lifting mechanism 7 first drives the piston plate 21, i.e., the conveying part 2, to descend. At this time, the first chamber 15 is gradually squeezed and reduced due to the descent of the piston plate 21, and the space of the second chamber 16 gradually expands until the piston plate 21 descends to the bottom opening of the filling nozzle 1. At this time, the first chamber 15 disappears, the second chamber 16 expands to its maximum, and the feeding mechanism 4 delivers the ointment into the second chamber 16 through the hose. Simultaneously, the first lifting mechanism 3 drives the filling nozzle 1 to descend and extend into the packaging bottle. Subsequently, the switching mechanism 6 at the bottom of the filling nozzle 1 opens, and the electrically controlled valve 22 in the piston plate 21 opens. Under the continuous feeding of the feeding mechanism 4, the ointment is gradually filled into the packaging bottle through the second chamber 16 and the electrically controlled valve 22. In this embodiment, a flow valve (not shown) can also be installed in the hose to monitor the flow rate of the ointment flowing from the feeding mechanism 4 into the packaging bottle, so as to achieve quantitative filling of the ointment. When the packaging bottle is filled... After filling, some ointment will adhere to the first side of the piston plate 21. Then, the switching mechanism 6 at the bottom of the filling nozzle 1, corresponding to the switching mechanism 6 in the first chamber 15, closes. That is, both switching mechanisms 6 at both ends of the filling nozzle 1 are closed. With the electronically controlled valve 22 open, the second lifting mechanism 7 drives the piston plate 21 to rise. Since the second chamber 16 is now filled with ointment (i.e., the ointment is above the piston plate 21), the rising of the piston plate 21 gradually compresses the space within the second chamber 16, causing the second chamber 16 to... The space inside 6 gradually shrinks, the space inside the first chamber 15 gradually increases, and the ointment in the second chamber 16 is squeezed into the first chamber 15 until the piston plate 21 moves to the upper end of the filling nozzle 1. The second chamber 16 is squeezed out by the piston plate 21, the first chamber 15 expands to its maximum, and the ointment in the second chamber 16 enters the first chamber 15 with the squeeze of the piston plate. The ointment attached to the first side of the piston plate 21 is also mixed into the first chamber 15. At this time, the ointment is located below the piston plate 21. Subsequently, in the second stroke, the output shaft of the drive motor 82 drives the connecting rod 85 to rotate. The connecting rod 85 drives the filling nozzle 1 to revolve through the collar 84. After the filling nozzle 1 revolves 180°, the second chamber 16 rotates to the bottom of the piston plate 21, and the first chamber 15 rotates to the top of the piston plate 21. That is, the ointment rotates to the top of the piston plate 21 again. At this time, the piston plate 21 is located at the lower opening of the filling nozzle 1 after rotation. Then, the filling nozzle 1 is inserted into the subsequent packaging bottle again, and the electronically controlled valve 22 inside the piston plate 21 opens again. During the continuous feeding process of the feeding mechanism 4, the ointment in the first chamber 15 passes through the piston plate 21 and is poured into the packaging bottle. Through the rotation of the filling nozzle 1, the piston plate 21 remains below the ointment during filling, meaning it always serves as the outlet for the ointment. The switching mechanisms at both ends of the filling nozzle 1 are not used as the outlet. Furthermore, the opening of the electrically controlled valve 22 is smaller than the opening diameter of the switching mechanism 6, so the ointment falls directly from the electrically controlled valve 22 onto the packaging bottle. It will not stick to the filling nozzle 1. That is to say, under the overall flow of the ointment in the first chamber 15, the ointment adhering to the first side of the piston plate 21 in the first stroke will also flow with the ointment in the first chamber 15 and be filled into the packaging bottle. It can be understood that the ointment adhering to the first side of the piston plate 21 will also be included in the subsequent ointment filling measurement unit, thereby reducing the waste during ointment filling. Similarly, in the second stroke, some ointment will also adhere to the second side of the piston plate 21. When the subsequent first stroke is carried out... During the stroke, the ointment adhering to the second side also mixes with the ointment in the second chamber 16, and flows with the ointment in the second chamber 16 during the filling process and is poured into the subsequent packaging bottle. Therefore, although ointment may adhere to the side of the piston plate 21 during the multiple sequential first and second strokes, in subsequent first or second strokes, the adhered ointment will be poured into the packaging bottle along with the flow of ointment in the first chamber 15 or the second chamber 16, thus reducing ointment waste. Secondly, in the first and second strokes, although ointment adheres to the side of the piston plate 21 at the end of each first or second stroke, as the adhered ointment is poured into the packaging bottle in subsequent strokes, and the subsequent ointment, that is, the ointment entering the filling nozzle 1 from the feeding mechanism 4, continues to adhere to the side of the piston plate 21, it can be understood that in multiple cycles of the first and second strokes, the ointment adhering to the side of the piston plate 21 is constantly replaced by the subsequent ointment. Although the side of the piston plate 21 will continuously have ointment adhering to it, the ointment adhering to it each time is different, so there will be no problem of the ointment on the side of the piston plate 21 drying and hardening due to long-term adhesion. Thus, there will be no problem of ointment layering and adhering to hardened ointment or the electric control valve 22 being blocked.

[0029] In an optional embodiment, preferably, the second lifting mechanism 7 includes an electric push rod 71 and a magnetic ring 72. The filling nozzle 1 includes an inner tube 11 and an outer tube 12. The outer tube 12 is sleeved outside the inner tube 11, and a receiving groove 13 is formed between the outer tube 12 and the inner tube 11. The magnetic ring 72 is located in the receiving groove 13. A metal block is installed inside the piston plate 21. The piston plate 21 is magnetically connected to the magnetic ring 72 through the metal block. The outer wall of the magnetic ring 72 is provided with a protrusion 73. A sliding groove is opened on the outer wall of the outer tube 12. The protrusion 73 is located in the sliding groove and forms a sliding guide engagement with the sliding groove. The electric push rod 71 is used to drive the protrusion 73 to move along the groove direction of the sliding groove.

[0030] Specifically, the electric push rod 71 is arranged vertically and installed on one side of the filling nozzle 1. The fixed end of the electric push rod 71 is fixedly connected to the support plate 81, such as... Figure 3 and Figure 4 As shown, the collar 84 has a through hole 86, which corresponds to and communicates with the slide groove. The axis of the inner tube 11 is collinear with the axis of the outer tube 12, and the groove direction is consistent with the axial direction of the outer tube 12. In actual use, when the piston plate 21 needs to be driven down, the telescopic shaft at the output end of the electric push rod 71 begins to extend. The telescopic shaft contacts the protrusion 73 and drives the protrusion 73 to descend in the slide groove. The descent of the protrusion 73 drives the magnetic ring 72 to descend in the receiving groove 13. At this time, driven by magnetic force, the magnetic ring 72 passes through the magnetic field. The piston plate 21 descends synchronously due to the force of the magnetic ring 72, achieving a contactless descent. Similarly, the telescopic shafts of the protrusion 73 and the electric push rod 71 are also made of metal. Therefore, after the telescopic shaft contacts the protrusion 73, one end of the telescopic shaft is also attracted to the protrusion 73 by the magnetic force transmitted by the magnetic ring 72. Thus, when the telescopic shaft retracts, it can also drive the protrusion 73 and the magnetic ring 72 to rise synchronously, thereby driving the piston plate 21 to rise. This achieves the vertical lifting and lowering of the piston plate 21 within the inner tube 11, i.e., the filling nozzle 1. Furthermore, by utilizing the separate structure of the electric push rod 71 and the magnetic ring 72, when the magnetic ring 72 and the piston plate 21 rise to their limit positions, the telescopic shaft of the electric push rod 71 continues to retract. At this time, the electric push rod 71 can disengage from the contact with the protrusion 73. After the electric push rod 71 disengages, the drive mechanism 8 can drive the filling nozzle 1 to rotate. The rotated protrusion 73 is located at the lower end of the filling nozzle 1. Subsequently, the telescopic shaft of the electric push rod 71 extends again, passes through the collar 84 and contacts the protrusion 73. The lower end of the telescopic shaft is attracted to the protrusion 73 again. The extension and retraction of the telescopic shaft can then drive the magnetic ring 72 to rise and fall again, thereby achieving the lifting and lowering control of the rotated piston plate 21. Moreover, the setting of the electric push rod 71 does not affect the rotation of the filling nozzle 1.

[0031] It should be added that, such as Figure 4As shown, the magnetic ring 72 has a C-shaped structure, that is, the magnetic ring 72 has a notch. Since the pipe of the feeding mechanism 4 passes through the inner pipe 11 and the outer pipe 12, and part of the pipe is located in the receiving groove 13, in order to avoid the pipe part, a notch is set on the magnetic ring 72, which corresponds to the pipe part in the receiving groove 13.

[0032] The foregoing has only described certain exemplary embodiments of the present invention by way of illustration. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the foregoing drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. An integrated pharmaceutical raw material filling device, comprising a filling nozzle (1), a first lifting mechanism (3), and a feeding mechanism (4), wherein the first lifting mechanism (3) is used to drive the filling nozzle (1) to move vertically up and down, and the feeding mechanism (4) is connected to the inside of the filling nozzle (1) through a pipe, characterized in that, The filling nozzle (1) is hollow inside and can be sealed at the bottom. A feeding part (2) is installed inside the filling nozzle (1). The ointment is filled into the packaging bottle from the feeding part (2). The feeding part (2) can be vertically raised and lowered inside the filling nozzle (1). It also includes a second lifting mechanism (7), which is used to drive the material conveying part (2) to move vertically up and down inside the filling nozzle (1); It also includes a drive mechanism (8), which is used to drive the filling nozzle (1) to rotate up and down; The drive mechanism (8) includes a support plate (81), a drive motor (82), a fixed plate (83), a collar (84), and a connecting rod (85). The support plate (81) is fixedly installed on the output shaft of the first lifting mechanism (3). The upper end of the fixed plate (83) is fixedly connected to the support plate (81). The drive motor (82) is installed on the outer wall of the fixed plate (83). The collar (84) is fixedly sleeved on the outer wall of the filling nozzle (1). The output shaft of the drive motor (82) is fixedly connected to the collar (84) through the connecting rod (85). The filling nozzle (1) is provided in multiple sets. Each set of filling nozzles (1) has a collar (84) fixedly fitted on its outer wall. Each set of collars (84) is connected by a connecting rod (85). The central axis of the connecting rod (85) is collinear with the axis of the output shaft of the drive motor (82) and is arranged horizontally. The second lifting mechanism (7) includes an electric push rod (71) and a magnetic ring (72). The filling nozzle (1) includes an inner tube (11) and an outer tube (12). The outer tube (12) is sleeved outside the inner tube (11). A receiving groove (13) is formed between the outer tube (12) and the inner tube (11). The magnetic ring (72) is located in the receiving groove (13). A metal block is installed inside the piston plate (21). The piston plate (21) is magnetically connected to the magnetic ring (72) through the metal block. A protrusion (73) is provided on the outer wall of the magnetic ring (72). A sliding groove is opened on the outer wall of the outer tube (12). The protrusion (73) is located in the sliding groove and forms a sliding guide engagement with the sliding groove. The electric push rod (71) is used to drive the protrusion (73) to move along the groove of the sliding groove. When it is necessary to drive the piston plate (21) to descend, the telescopic shaft at the output end of the electric push rod (71) begins to extend, the telescopic shaft contacts the protrusion (73), and drives the protrusion (73) to descend in the groove.

2. The integrated filling equipment for active pharmaceutical ingredients according to claim 1, characterized in that, The filling nozzle (1), the first lifting mechanism (3), and the feeding mechanism (4) are all installed on the frame. The feeding mechanism (4) is connected to the inner wall of the filling nozzle (1) through a hose.

3. The integrated filling equipment for active pharmaceutical ingredients according to claim 2, characterized in that, A conveying mechanism (5) is also installed on the frame, and the packaging bottles are arranged vertically on the conveying mechanism (5).

4. The integrated filling equipment for active pharmaceutical ingredients according to claim 1, characterized in that, The bottom of the filling nozzle (1) is provided with a switch mechanism (6), which is used to control the opening and closing of the bottom opening of the filling nozzle (1).

5. The integrated filling equipment for active pharmaceutical ingredients according to claim 1, characterized in that, The material conveying section (2) includes a piston plate (21), which is dynamically sealed inside the filling nozzle (1), and an electrically controlled valve (22) is installed at the center of the piston plate (21).

6. The integrated filling equipment for active pharmaceutical ingredients according to claim 1, characterized in that, The electric push rod (71) is arranged vertically. The fixed end of the electric push rod (71) is fixedly connected to the support plate (81). The collar (84) is provided with a through hole (86). The through hole (86) corresponds to and is connected to the slide groove. The axis of the inner tube (11) is collinear with the axis of the outer tube (12). The groove direction is consistent with the axis of the outer tube (12).

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