A medical sample concentration detection device

CN118833522BActive Publication Date: 2026-09-22SHIJIAZHUANG BUMU ELECTRONIC CO LTD
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Patent Information

Application Number
CN202411265982.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-09-11
Publication Date
2026-09-22
Estimated Expiration
2044-09-11

AI Technical Summary

Technical Problem

[0005]本发明的目的在于提供一种医用样本浓度检测装置,旨在解决现有技术中对医用血液药物样本浓度的检测时存在需要工作人员多次移送样本,导致样本浓度检测速度慢,检测效率低的技术问题

Benefits of technology

[0016]本发明提供的一种医用样本浓度检测装置的有益效果在于:与现有技术相比,本发明一种医用样本浓度检测装置包括折叠箱、冷藏冷冻箱、混合组件、离心机和手持式浓度检测仪,折叠箱内部形成空腔,折叠箱能移动至任意位置,空腔内部形成有多个容纳盒;冷藏冷冻箱设置于一个容纳盒内,冷藏冷冻箱用于冷藏或冷冻血液样本,冷藏冷冻箱上端面形成有用于盛放血液样本的放置区;混合组件设置于一个容纳盒内,用于向血液样本内注入溶液;离心机设置于一个容纳盒内,用于对血液样本进行离心处理;手持式浓度检测仪连接于折叠箱外壁,用于对血液样本中的药物浓度值进行检测;其中,折叠箱打开后露出冷藏冷冻箱、混合组件和离心机,使用手持式浓度检测仪进行浓度检测,解决了对血液药物样本浓度的检测时存在需要工作人员多次移送样本,导致样本浓度检测速度慢,检测效率低的技术问题,具有省去人工往返移送样本,提高血药浓度检测速度和效率的技术效果。

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Abstract

The application provides a medical sample concentration detection device, belonging to the technical field of concentration detection, comprising a folding box, a refrigeration and freezing box, a mixing assembly, a centrifuge and a handheld concentration detector, the refrigeration and freezing box is arranged in the containing box, the refrigeration and freezing box is used for refrigerating or freezing a blood sample, and a placing area for containing the blood sample is formed on the upper end face of the refrigeration and freezing box; the mixing assembly is arranged in the containing box and is used for injecting a solution into the blood sample; the centrifuge is arranged in the containing box and is used for centrifugal treatment of the blood sample; and the handheld concentration detector is connected to the outer wall of the folding box and is used for detecting the concentration value of a drug in the blood sample; wherein the refrigeration and freezing box, the mixing assembly and the centrifuge are exposed after the folding box is opened, and the concentration is detected by using the handheld concentration detector. The medical sample concentration detection device has the technical effects of saving manual back-and-forth sample transfer and improving blood drug concentration detection speed and efficiency.
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Description

Technical Field

[0001] This invention belongs to the field of concentration detection technology, and more specifically, relates to a medical sample concentration detection device. Background Technology

[0002] Blood drug concentration monitoring is the most important aspect of therapeutic drug monitoring. Accurate determination of blood drug concentrations is crucial for clinically adjusting drug dosages and developing individualized dosing regimens. Several analytical methods for detecting blood concentrations of immunosuppressant drugs have been developed, including chemiluminescent microparticle immunoassay, enzyme-amplified immunoassay, microparticle immunoassay, enzyme-linked immunosorbent assay (ELISA), high-performance liquid chromatography (HPLC), and liquid chromatography-tandem mass spectrometry (LC-MS / MS). Among these, LC-MS / MS is specific, sensitive, and reliable. Due to its high precision, accuracy, sensitivity, and high throughput, it is gradually replacing immunoassays as the primary method for monitoring clinical immunosuppressant blood concentrations.

[0003] Medical drug concentration refers to the total concentration of a drug in the plasma after absorption, including drugs bound to plasma proteins or free in the plasma. Sometimes it can also refer to the concentration of a drug in whole blood. The intensity of a drug's effect is directly proportional to its concentration in plasma. Drug concentration in the body changes over time, and high-performance liquid chromatography (HPLC) is the primary method for monitoring concentration. Currently, some hospitals with the necessary resources are increasingly measuring blood drug concentrations for patients, in addition to monitoring drug dosage and frequency, to guide clinicians in selecting the optimal treatment plan and dosage for different individuals.

[0004] In existing technologies, the detection of blood drug sample concentration requires staff to move back and forth between the blood collection area and the concentration detection area. When there are a large number of samples to be tested, staff need to transfer the samples multiple times. This results in low sample concentration detection efficiency, slow detection speed, and long result output time. Summary of the Invention

[0005] The purpose of this invention is to provide a medical sample concentration detection device, which aims to solve the technical problem in the prior art that the detection of medical blood drug sample concentration requires multiple sample transfers by staff, resulting in slow sample concentration detection speed and low detection efficiency.

[0006] To achieve the above objectives, the technical solution adopted by the present invention is: to provide a medical sample concentration detection device, comprising: A folding box with an internal cavity, the folding box can be moved to any position, and multiple storage boxes are formed inside the cavity; A refrigerated freezer is disposed within one of the aforementioned containers. The refrigerated freezer is used to refrigerate or freeze blood samples, and the upper surface of the refrigerated freezer has a placement area for holding blood samples. A mixing component, disposed within one of the aforementioned containers, is used to inject a solution into a blood sample; A centrifuge, disposed within one of the aforementioned containers, is used for centrifuging blood samples; A handheld concentration detector, connected to the outer wall of the folding box, is used to detect the drug concentration in blood samples; When the folding box is opened, the refrigerated / frozen box, the mixing assembly, and the centrifuge are exposed, and the concentration is detected using the handheld concentration detector.

[0007] In one possible implementation, the centrifuge is connected to a liquid chromatograph at its upper end, the liquid chromatograph being used to detect the drug concentration in the blood sample.

[0008] In one possible implementation, the inner wall of the folding box is provided with a first rotating platform, and a telescopic column is connected to the upper end of the first rotating platform. After the refrigerator / freezer is moved, it can be placed on the upper end of the telescopic column. The upper end of the first rotating platform has a circumferential rotational degree of freedom in the horizontal plane, and the telescopic column has a vertical telescopic degree of freedom. The refrigerator / freezer has a cavity inside and an opening on one side. The refrigerator / freezer adjusts the orientation of the opening by means of the first rotating platform and adjusts its height by means of the telescopic column.

[0009] In one possible implementation, the refrigerator / freezer contains multiple small refrigerators, each used to store different blood samples. Each small refrigerator has a door, which is located on the same side as the opening. The top of the refrigerator / freezer has a vent, and a fan is installed inside the vent to dissipate heat from the inside of the refrigerator / freezer. The placement area is positioned to avoid the fan.

[0010] In one possible implementation, a sample box is provided in the placement area, a magnet is provided at the bottom of the sample box, the top of the refrigerator / freezer is made of magnetic material, the magnet is magnetically attracted to the top of the refrigerator / freezer, and the top of the sample box is provided with multiple placement holes, into which a container is inserted for holding blood samples.

[0011] In one possible implementation, a second rotating platform is provided on the inner side wall of the folding box. A lifting column is connected to the upper end of the second rotating platform. The upper end of the second rotating platform has a circumferential rotational degree of freedom in the horizontal plane. The lifting column has a vertical extension and retraction degree of freedom. A robotic arm is connected to the upper end of the lifting column. The robotic arm is used to move blood samples.

[0012] In one possible implementation, a heater for heating blood samples is connected within the receiving container, the heater comprising: The support assembly, with its bottom end connected to the inner wall of the folding box, has a vertical extension and retraction degree of freedom; An arc-shaped plate is connected to the upper end of the support assembly, and is arranged in an arc shape with one side of the arc protrusion facing upward; A heating component is slidably connected to the arc-shaped plate and has a degree of freedom to slide along the arc direction of the arc-shaped plate. The heating component is close to and toward the blood sample to heat the blood sample.

[0013] In one possible implementation, the inner sidewall of the folding box is connected to a slide rail, and a telescopic rod is slidably connected to the slide rail. The length direction of the slide rail is along the length direction of the folding box, and the telescopic rod has a vertical extension and retraction degree of freedom. A machine vision inspection component is connected to the upper end of the telescopic rod, and the machine vision inspection component is used to perform machine vision inspection toward the blood sample.

[0014] In one possible implementation, the hybrid component includes: Injection tray, used to hold blood samples to be mixed with the solution; A spare tray, located at the bottom of the injection tray, is used to hold blood samples and is stacked on top of the injection tray. A syringe is hinged to the outer wall of the injection tray. The syringe is used to inject a solution into a blood sample. After the syringe is rotated, a plane is formed in a vertical plane. The syringe has two states: the state in which the syringe is located outside the injection tray is defined as the first state, and the state in which the syringe is rotated and located above the injection tray and used to inject a solution into a blood sample is defined as the second state. The syringe switches between the first state and the second state. A pumping assembly, connected to the syringe, is used to aspirate a solution and pump it into the syringe.

[0015] In one possible implementation, a photovoltaic power supply component is connected to the outer wall of the folding box. The power output terminal of the photovoltaic power supply component is electrically connected to the refrigerator / freezer, the centrifuge, and the handheld concentration detector, respectively, and is used to supply power to each of them.

[0016] The beneficial effects of the medical sample concentration detection device provided by this invention are as follows: Compared with the prior art, the medical sample concentration detection device of this invention includes a folding box, a refrigerated / frozen box, a mixing component, a centrifuge, and a handheld concentration detector. The folding box has an internal cavity that can be moved to any position, and multiple receiving boxes are formed inside the cavity. The refrigerated / frozen box is disposed within one of the receiving boxes and is used to refrigerate or freeze blood samples. The upper surface of the refrigerated / frozen box has a placement area for holding blood samples. The mixing component is disposed within one of the receiving boxes and is used to inject into the blood sample. The solution; a centrifuge is housed in a container for centrifuging blood samples; a handheld concentration detector is attached to the outer wall of the folding box for detecting drug concentrations in the blood samples; when the folding box is opened, a refrigerated / freezing box, a mixing assembly, and a centrifuge are exposed. The use of the handheld concentration detector for concentration detection solves the technical problem of requiring multiple sample transfers by staff, resulting in slow detection speed and low efficiency. It effectively eliminates the need for manual sample transfers, improving the speed and efficiency of blood drug concentration detection. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the external structure of a medical sample concentration detection device provided in an embodiment of the present invention; Figure 2 This is a schematic diagram of the internal structure of a medical sample concentration detection device provided in an embodiment of the present invention; Figure 3 This is a schematic diagram of the structure of a refrigerated freezer for a medical sample concentration detection device provided in an embodiment of the present invention; Figure 4 This is a schematic diagram of the centrifuge and liquid chromatograph of a medical sample concentration detection device provided in an embodiment of the present invention; Figure 5 A schematic diagram of a machine vision detection component and its connection to a medical sample concentration detection device provided in an embodiment of the present invention; Figure 6 This is a schematic diagram of the hybrid component structure of a medical sample concentration detection device provided in an embodiment of the present invention; Figure 7 This is a schematic diagram of the heater structure of a medical sample concentration detection device provided in an embodiment of the present invention; Figure 8 A schematic diagram of the heater structure of a medical sample concentration detection device provided in another embodiment of the present invention; Figure 9 This is a schematic diagram of the structure of a nitrogen blower for a medical sample concentration detection device provided in an embodiment of the present invention.

[0019] Explanation of reference numerals in the attached figures: 1. Folding box; 11. Storage box; 12. Handheld concentration detector; 2. Refrigerator / freezer; 21. Opening; 22. Mini-fridge; 23. Door; 24. Fan; 3. Mixing assembly; 31. Injection tray; 32. Spare tray; 33. Injector; 34. Pumping assembly; 35. Sensor; 4. Centrifuge; 5. Liquid Chromatography (HPLC); 6. First rotating platform; 61. Flat plate; 7. Telescopic bollards; 8. Control Panel; 9. Sample box; 91. Magnet; 92. Placement hole; 93. Container; 10. Second rotating platform; 13. Lifting column; 14. Robotic arm; 15. Heater; 151. Support assembly; 152. Arc plate; 153. Heating assembly; 154. Heating wire; 155. Slider; 156. Telescopic cylinder; 157. Mounting plate; 158. Push rod; 16. Slide rail; 161. Telescopic rod; 162. Machine vision inspection assembly; 163. Support rod; 17. Photovoltaic power supply assembly; 18. Nitrogen blowing device. Detailed Implementation

[0020] To make the technical problems to be solved, the technical solutions, and the beneficial effects of the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present invention and are not intended to limit the present invention.

[0021] Please refer to the following: Figures 1 to 9The present invention provides a medical sample concentration detection device. This medical sample concentration detection device includes a folding box 1, a refrigerated / frozen box 2, a mixing component 3, a centrifuge 4, and a handheld concentration detector 12. The folding box 1 has an internal cavity and can be moved to any position. Multiple receiving boxes 11 are formed inside the cavity. The refrigerated / frozen box 2 is disposed within one of the receiving boxes 11 and is used to refrigerate or freeze blood samples. The upper surface of the refrigerated / frozen box 2 has a placement area for holding the blood samples. The mixing component 3 is disposed within one of the receiving boxes 11 and is used to inject a solution into the blood sample. The centrifuge 4 is disposed within one of the receiving boxes 11 and is used to centrifuge the blood sample. The handheld concentration detector 12 is connected to the outer wall of the folding box 1 and is used to detect the drug concentration value in the blood sample. When the folding box 1 is opened, the refrigerated / frozen box 2, the mixing component 3, and the centrifuge 4 are exposed, and the concentration is detected using the handheld concentration detector 12.

[0022] The present invention provides a medical sample concentration detection device. Compared with the prior art, by setting up a folding box 1 to accommodate and place a refrigerated freezer 2, a mixing component 3, and a centrifuge 4, the folding box 1 can move in any direction to get close to the blood sample collection area and quickly perform sample concentration detection. This solves the technical problem that the detection of blood drug sample concentration requires staff to transfer the sample multiple times, resulting in slow sample concentration detection speed and low detection efficiency. It has the technical effect of eliminating manual back-and-forth sample transfer and improving the speed and efficiency of blood drug concentration detection.

[0023] The folding suitcase 1 is equipped with wheels at its bottom. It is composed of multiple panels assembled together, similar to the modular assembly structure of existing folding suitcases. The wheels are located at the bottom of the suitcase, allowing workers to move it by pulling it and causing the wheels to roll on the ground, thus reducing the labor intensity of handling the suitcase. The installation and rolling mechanism of the wheels are similar to those of the wheels on a suitcase.

[0024] In some embodiments, please refer to Figures 1 to 9 The centrifuge 4 is connected to a liquid chromatograph 5 at the top, which is used to detect the drug concentration in the blood sample.

[0025] When blood samples need to be refrigerated or frozen, the refrigeration / freezing box 2 can be used to preserve the samples. The refrigeration and freezing temperatures can be controlled to meet the requirements for concentration detection and preservation. When blood samples need to be mixed with other solutions, the mixing component 3 is used. First, the blood sample is placed on the mixing component 3, and then a solution (such as working solution or stock solution in the prior art) is injected into the sample (all referring to blood samples) to obtain a mixture, which can then be used for concentration detection. The centrifuge 4 in this embodiment is a machine for centrifuging liquids in the prior art. When a sample needs to be centrifuged, it is placed in the centrifuge 4 for centrifugation. The liquid chromatograph 5 in this embodiment is a high-performance liquid chromatograph in the prior art, that is, an instrument that uses high-performance liquid chromatography for concentration detection.

[0026] In some embodiments, please refer to Figures 1 to 9 The inner wall of the folding box 1 is equipped with a first rotating platform 6, and a telescopic column 7 is connected to the upper end of the first rotating platform 6. The refrigerated freezer 2 can be placed on the upper end of the telescopic column 7. The upper end of the first rotating platform 6 has a circumferential degree of freedom in the horizontal plane, and the telescopic column 7 has a vertical extension and retraction degree of freedom. The interior of the refrigerated freezer 2 is hollow, and an opening 21 is provided on one side. The orientation of the opening 21 of the refrigerated freezer 2 can be adjusted by means of the first rotating platform 6, and the height can be adjusted by means of the telescopic column 7. The first rotating platform 6 can achieve circumferential rotation, thereby adjusting the orientation or position of the refrigerated freezer 2, which facilitates the placement or removal of samples by the staff, improving the flexibility and convenience of operation. The height of the refrigerated freezer 2 can be adjusted by means of the telescopic column 7, which facilitates the staff to pick up and place samples, improving the flexibility of operation.

[0027] In this embodiment, both the first rotating platform 6 and the telescopic column 7 are existing technology products. The telescopic column 7 is vertically arranged and its bottom end is connected to the upper end of the first rotating platform 6. The bottom end of the first rotating platform 6 is connected to the flat plate 61, which is located on the inner side wall of the folding box 1.

[0028] The present invention also includes a control panel 8, the first rotating platform 6 is an electric rotating platform and is electrically connected to the control panel 8, and its operation is controlled by the control panel 8, and the telescopic column 7 is also an electrically controlled telescopic column, electrically connected to the control panel 8, and its operation is controlled by the control panel 8.

[0029] In some embodiments, please refer to Figures 1 to 9The refrigerator / freezer 2 contains multiple small refrigerators 22, each used to store different blood samples. Each small refrigerator 22 has a door 23, which is located on the same side as the opening 21. A ventilation opening is located on the top of the refrigerator / freezer 2, and a fan 24 is installed inside the ventilation opening to dissipate heat from the interior of the refrigerator / freezer 2. The sample placement area is positioned to avoid the fan 24. In this embodiment, two small refrigerators 22 are used, spaced apart, both with refrigeration and freezing functions, and both can be used to preserve samples. The small refrigerators 22 are existing technology products that can be embedded inside the refrigerator / freezer 2, and are inserted and removed from the opening 21 side. To enhance heat dissipation, the fan 24 blows air into the refrigerator / freezer 2, and the hot air escapes from the opening 21. Opening the door 23 of the small refrigerator 22 on the opening 21 side allows samples to be placed inside, which is also beneficial for long-term preservation.

[0030] To ensure proper sample preservation and placement, and to prevent spillage during sample transport, please refer to the following embodiments in some cases. Figures 1 to 9 A sample box 9 is provided in the placement area. A magnet 91 is installed at the bottom of the sample box 9. The top of the refrigerator / freezer 2 is made of magnetic material. The magnet 91 is magnetically attracted to the top of the refrigerator / freezer 2. Multiple placement holes 92 are provided on the top of the sample box 9, and containers 93 are inserted into the placement holes 92 to hold blood samples. This embodiment includes multiple containers 93, which can be beakers, flasks, test tubes, or other glassware. Containers 93 used in the medical field are used to hold blood samples, ensuring no spillage, etc., and are generally vertically inserted into the placement holes 92 to maintain an upright position. Multiple placement holes 92 are arranged in a rectangular array inside the sample box 9, allowing multiple containers 93 to be placed. To prevent the sample box 9 from sliding during transport, a magnet 91 is provided at the bottom of the sample box 9, enabling magnetic attraction with the top of the refrigerator / freezer 2, thus fixing the sample box 9 in place. Simultaneously, the containers 93 will not slide out of the sample box 9, ensuring effective sample placement.

[0031] To facilitate the transfer of container 93 or samples and improve the level of automation, please refer to the following embodiments in some cases. Figures 1 to 9A second rotating platform 10 is provided on the inner wall of the folding box 1. A lifting column 13 is connected to the upper end of the second rotating platform 10. The upper end of the second rotating platform 10 has a circumferential rotational degree of freedom in the horizontal plane, and the lifting column 13 has a vertical extension and retraction degree of freedom. A robotic arm 14 is connected to the upper end of the lifting column 13. The robotic arm 14 is used to move blood samples. In this embodiment, the second rotating platform 10 has the same structure as the first rotating platform 6 and is also electrically connected to the control panel 8. The lifting column 13 is also a prior art product, capable of vertical extension and retraction, thereby adjusting the height of the robotic arm 14. The rotation angle of the robotic arm 14 can be adjusted through the second rotating platform 10, thereby facilitating the operation or grasping of the container 93 by the robotic arm 14. The robotic arm 14 in this embodiment is a prior art product, such as a six-axis robotic arm, capable of adjustment or movement in six directions, enabling the grasping of the container 93 at different positions, and movement in different directions or positions, such as placing the container 93 inside the refrigerator / freezer 2 or inside the centrifuge 4. In addition to the procedures that the robotic arm 14 can operate, the present invention can also cooperate with human staff to perform collaborative operations, thereby completing the concentration detection operation of the present invention.

[0032] Preferably, the robotic arm 14 is electrically connected to the control panel 8 and its operation is controlled by the control panel 8.

[0033] In some embodiments, please refer to Figures 1 to 9 The container 11 contains a heater 15 for heating blood samples. The heater 15 includes a support assembly 151, an arc-shaped plate 152, and a heating assembly 153. The bottom end of the support assembly 151 is connected to the inner wall of the folding box 1, and it has a vertical extension / retraction degree of freedom. The arc-shaped plate 152 is connected to the upper end of the support assembly 151, is arc-shaped, and its convex side faces upwards from the folding box 1. The heating assembly 153 is slidably connected to the arc-shaped plate 152, and has a sliding degree of freedom along the arc direction of the arc-shaped plate 152. The heating assembly 153 is close to and faces the blood sample to heat it. The support assembly 151 can be in two sets, such as... Figure 7 The settings can also be in a group, such as Figure 8 The configuration includes a telescopic component that can extend and retract axially, thereby adjusting the height of the heating assembly 153. The arc reading of the arc plate 152 is unrestricted, such as... Figure 7 The structure of the curved plate 152 in the middle, or as... Figure 8The structure of the arc-shaped plate 152 is described. By sliding the heating component 153 on the arc-shaped plate 152, the heating position of the heating component 153 can be adjusted, allowing it to be brought closer to the container 93 for sample heating. The heating component 153 can be electrically connected to the control panel 8; by controlling the operation of the heating component 153, the heating temperature of the sample can be controlled. In this embodiment, the container 93 is placed inside the sample box 9, and the heating component 153 is used to bring it closer to the sample for heating. When the heater 153 is not needed, it is retracted inside the folding box 1, allowing the folding box 1 to accommodate the heater 15.

[0034] Specifically, Figure 7 The heating component 153 includes three electric heaters, all slidably connected to the arc-shaped plate 152. Each heater can heat the same container 93, allowing for rapid sample heating. One or two electric heaters can also be used, heating the sample directly; the appropriate choice depends on the specific circumstances. A heating wire 154 is positioned between two electric heaters. When energized, the heating wire 154 generates heat, ensuring uniform heating of the container 93 and the sample. The electric heaters can be in contact with or not in contact with the container 93 to heat the sample. When multiple electric heaters operate simultaneously, the temperature within the area enclosed by the arc-shaped plate 152 is higher than the external temperature. Positioning the arc-shaped plate 152 above the sample box 9 allows for heating of the multiple containers 93 and the sample within the sample box 9.

[0035] like Figure 8 As shown, a slider 155 is slidably connected to the lower end of the arc-shaped plate 152. An adjustable telescopic cylinder 156 is connected to the lower end of the slider 155. The upper end of the telescopic cylinder 156 is hinged to the slider 155, and the lower end is hinged to a mounting plate 157. A push rod 158 is connected between the telescopic cylinder 156 and the slider 155. The push rod 158 is an electric push rod, electrically connected to the control panel 8, and its operation is controlled by the control panel 8. By pushing the telescopic cylinder 156, the rotation angle of the telescopic cylinder 156 can be adjusted, thereby adjusting the heating position of the electric heater. Multiple electric heaters are installed at the bottom of the mounting plate 157, which is also arc-shaped. By adjusting the length of the telescopic cylinder 156, its rotated position, and the position or orientation of the mounting plate 157, the heating position of the electric heater on the container 93 or sample can be adjusted, thereby adjusting the heating position of the sample. The telescopic cylinder 156 is manually adjustable, and its length after extension can be limited. The angle of the mounting plate 157 relative to the telescopic cylinder 156 after rotation can also be limited. For details, please refer to the existing technology, which will not be described here. In summary, the heating position of the electric heater on the sample can be adjusted.

[0036] In some embodiments, please refer to Figures 1 to 9The inner wall of the folding box 1 is connected to a slide rail 16, and a telescopic rod 161 is slidably connected to the slide rail 16. The slide rail 16 extends along the length of the folding box 1, and the telescopic rod 161 has a vertical extension and retraction degree of freedom. A machine vision inspection component 162 is connected to the upper end of the telescopic rod 161. The machine vision inspection component 162 is used to perform machine vision inspection on the blood sample. By adjusting the position and length of the telescopic rod 161, the detection position of the machine vision inspection component 162 can be adjusted, thereby enabling machine vision inspection of the sample. If impurities are present in the sample, they can be detected by the machine vision inspection component, which can then alert staff. In this embodiment, the machine vision inspection component can use existing technology products and has built-in sample data information. By taking pictures and collecting images, it can compare and analyze the data with the built-in information to ultimately determine whether the sample has quality defects, thus assisting staff in observing and identifying sample quality information. The slide rail 16 is located on the side near the moving vehicle body 1. By sliding the telescopic rod 161, the entire process of sample transfer can be captured or images can be acquired. By extending the telescopic rod 161 to different lengths, image acquisition of samples at different positions can be controlled. The machine vision inspection component 162 is electrically connected to the control panel 8 and its operation is controlled by the control panel 8.

[0037] Preferably, the telescopic rod 161 can be limited in length after extension. Three or four support rods 163 are provided at the upper end of the telescopic rod 161, which are combined to form an oval shape. Multiple CCD cameras are evenly distributed on the support rods 163, all of which are used to take images or record videos of the sample.

[0038] In some embodiments, please refer to Figures 1 to 9 The mixing assembly 3 includes an injection tray 31, a spare tray 32, a syringe 33, and a pumping assembly 34. The injection tray 31 holds the blood sample to be mixed with the solution. The spare tray 32 is located at the bottom of the injection tray 31 and is used to hold the blood sample; it is stacked on top of the injection tray 31. The syringe 33 is hinged to the outer wall of the injection tray 31 and is used to inject the solution into the blood sample. After rotation, the syringe 33 forms a plane in the vertical plane. The syringe 33 has two states: the first state is defined as the state where the syringe 33 is outside the injection tray 31, and the second state is defined as the state where the syringe 33 is rotated and located above the injection tray 31 and used to inject the solution into the blood sample. The syringe 33 switches between the first and second states. The pumping assembly 34 is connected to the syringe 33 and is used to aspirate the solution and pump it into the syringe 33. A container 93 containing the sample is placed inside the injection tray 31. Figure 6As shown, there are two containers 93, each a beaker. Unused beakers are placed in a spare tray 32. Two syringes 33 are positioned at opposite ends of the injection tray 31, injecting solution into each container 93. This improves the speed and efficiency of solution injection. In this embodiment, two spare trays 32 are stacked. The pumping assembly 34 can draw up the solution and pump it into the syringes 33. By starting and stopping the syringes 33, a precise amount of solution can be injected into the containers 93, mixing with the sample to form a mixture. The syringes 33 can be existing technology products, with one end hinged to the outer wall of the injection tray 31, and their rotation direction is as follows... Figure 6 As indicated by the middle arrow. When no solution is needed, syringe 33 is in the first state. During injection, rotating syringe 33 changes it to the second state, as shown. Figure 6 The state is the second state. The pumping assembly 34 can adopt the pump body and storage tank in the prior art. The storage tank contains the solution. The pump body is connected to the storage tank. The outlet of the pump body is connected to the syringe 33 through a pipe. The syringe 33 is equivalent to a nozzle or spray head. By controlling the opening time of the nozzle, the amount of solution injected into the container 93 can be controlled.

[0039] Preferably, the position of the syringe 33 is movable to inject solution into different containers 93, or to inject solution into different locations inside the container 93. Unused syringes 33 can be shut off. Sensors 35 are provided on the sides of the injection tray 31 and the spare tray 32 to detect the liquid level of the sample inside the container 93. The sensors 35 are electrically connected to the control panel 8 and send a liquid level signal to the control panel 8.

[0040] In some embodiments, please refer to Figures 1 to 9 A photovoltaic power supply module 17 is connected to the outer wall of the folding box 1. The power output terminals of the photovoltaic power supply module 17 are electrically connected to the refrigerator / freezer 2, centrifuge 4, and handheld concentration detector 12, respectively, and are used to supply power to each of them. A battery and an inverter are installed on the upper part of the mobile vehicle body 1. The power output terminal of the battery is electrically connected to the inverter, and the power output terminal of the inverter is electrically connected to the refrigerator / freezer 2, centrifuge 4, and handheld concentration detector 12, respectively, and is used to supply AC power to each of them. The power output terminal of the photovoltaic power supply module 17 is connected to the inverter, and the power output terminal of the inverter is connected to the aforementioned pumping module 34, machine vision inspection module 162, heater 15, multiple rotating tables, telescopic column 7, lifting column 13, etc., and is used to supply power to each of them.

[0041] Specifically, a nitrogen evaporator 18 is also connected inside the folding box 1. When the container 93 needs to use the nitrogen evaporator 18, it can be placed on the nitrogen evaporator 18 and operated. The nitrogen evaporator 18, as... Figure 9 As shown in the image.

[0042] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A medical sample concentration detection device, characterized in that, include: A folding box with an internal cavity, the folding box can be moved to any position, and multiple storage boxes are formed inside the cavity; A refrigerated freezer is disposed within one of the aforementioned containers. The refrigerated freezer is used to refrigerate or freeze blood samples, and the upper surface of the refrigerated freezer has a placement area for holding blood samples. A mixing component, disposed within one of the aforementioned containers, is used to inject a solution into a blood sample; A centrifuge, disposed within one of the aforementioned containers, is used for centrifuging blood samples; A handheld concentration detector, connected to the outer wall of the folding box, is used to detect the drug concentration in blood samples; When the folding box is opened, the refrigerated freezer, the mixing assembly, and the centrifuge are exposed, and the concentration is detected using the handheld concentration detector. The inner wall of the folding box is provided with a second rotating platform. A lifting column is connected to the upper end of the second rotating platform. The upper end of the second rotating platform has a circumferential rotational degree of freedom in the horizontal plane. The lifting column has a vertical extension and retraction degree of freedom. A robotic arm is connected to the upper end of the lifting column. The robotic arm is used to move blood samples.

2. The medical sample concentration detection device as described in claim 1, characterized in that, The centrifuge is connected to a liquid chromatograph at its upper end, which is used to detect the drug concentration in blood samples.

3. The medical sample concentration detection device as described in claim 1, characterized in that, The inner wall of the folding box is provided with a first rotating platform, and a telescopic column is connected to the upper end of the first rotating platform. After the refrigerator / freezer is moved, it can be placed on the upper end of the telescopic column. The upper end of the first rotating platform has a circumferential degree of freedom in the horizontal plane, and the telescopic column has a vertical extension and retraction degree of freedom. The refrigerator / freezer has a cavity inside and an opening on one side. The refrigerator / freezer adjusts the orientation of the opening with the first rotating platform and adjusts its height with the telescopic column.

4. The medical sample concentration detection device as described in claim 3, characterized in that, The refrigerator-freezer contains multiple small refrigerators, each used to store different blood samples. Each small refrigerator has a door, which is located on the same side as the opening. The top of the refrigerator-freezer has a ventilation opening, and a fan is installed inside the ventilation opening to dissipate heat from the inside of the refrigerator-freezer. The placement area is positioned to avoid the fan.

5. The medical sample concentration detection device as described in claim 1, characterized in that, The placement area is equipped with a sample box, and the bottom of the sample box is equipped with a magnet. The top of the refrigerator / freezer is made of magnetic material. The magnet is magnetically attracted to the top of the refrigerator / freezer. The top of the sample box is equipped with multiple placement holes, and a container is inserted into the placement holes. The container is used to hold blood samples.

6. The medical sample concentration detection device as described in claim 1, characterized in that, The container is equipped with a heater for heating blood samples, the heater comprising: The support assembly, with its bottom end connected to the inner wall of the folding box, has a vertical extension and retraction degree of freedom; An arc-shaped plate is connected to the upper end of the support assembly, and is arranged in an arc shape with one side of the arc protrusion facing the top of the folding box; A heating component is slidably connected to the arc-shaped plate and has a degree of freedom to slide along the arc direction of the arc-shaped plate. The heating component is close to and toward the blood sample to heat the blood sample.

7. The medical sample concentration detection device as described in claim 1, characterized in that, The inner wall of the folding box is connected to a slide rail, and a telescopic rod is slidably connected to the slide rail. The length direction of the slide rail is along the length direction of the folding box. The telescopic rod has a vertical extension and retraction degree of freedom. A machine vision inspection component is connected to the upper end of the telescopic rod. The machine vision inspection component is used to perform machine vision inspection on the blood sample.

8. The medical sample concentration detection device as described in claim 1, characterized in that, The hybrid component includes: Injection tray, used to hold blood samples to be mixed with the solution; A spare tray, located at the bottom of the injection tray, is used to hold blood samples and is stacked on top of the injection tray. A syringe is hinged to the outer wall of the injection tray. The syringe is used to inject a solution into a blood sample. After the syringe is rotated, a plane is formed in a vertical plane. The syringe has two states: the state in which the syringe is located outside the injection tray is defined as the first state, and the state in which the syringe is rotated and located above the injection tray and used to inject a solution into a blood sample is defined as the second state. The syringe switches between the first state and the second state. A pumping assembly, connected to the syringe, is used to aspirate a solution and pump it into the syringe.

9. A medical sample concentration detection device as described in claim 1, characterized in that, The outer wall of the folding box is connected to a photovoltaic power supply component. The power output terminal of the photovoltaic power supply component is electrically connected to the refrigerator / freezer, the centrifuge, and the handheld concentration detector, and is used to supply power to each of them.

Citation Information

Patent Citations

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