一种治疗缺血性肠病的中药组合物及其制备方法和应用
The method of preparing a combination of Gentiana macrophylla and Ligusticum chuanxiong through water extraction has solved the treatment problem of ischemic bowel disease, achieved the effects of reducing intestinal mucosal damage, improving intestinal peristalsis and inhibiting intestinal adhesions, and provided a new drug option for the treatment of ischemic bowel disease.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- FOURTH MILITARY MEDICAL UNIVERSITY
- Filing Date
- 2024-07-02
- Publication Date
- 2026-07-17
AI Technical Summary
There are few drugs available for treating ischemic bowel disease, and existing treatments may lead to reperfusion injury, increasing the difficulty of treatment. The pathological mechanism is complex, and there is a lack of ideal treatment measures.
A traditional Chinese medicine composition using Gentiana macrophylla and Ligusticum chuanxiong as the main ingredients in a ratio of 1:0.5 to 3 is prepared into a thick paste by water extraction. Pharmaceutically acceptable excipients are added to make capsules, granules or tablets for oral or enema administration to reduce intestinal mucosal damage, reduce vascular permeability and inhibit intestinal adhesion.
It significantly reduces intestinal mucosal damage, improves intestinal vascular permeability, inhibits intestinal adhesions, improves intestinal peristalsis, and alleviates acute mesenteric ischemia-reperfusion injury, thus exhibiting significant therapeutic effects on ischemic bowel disease.
Smart Images
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