A cleaning method for cleaning injection and suction needles in a tray

Abstract

The application discloses a cleaning method for injection and suction liquid needles of a cleaning disc, which comprises three mechanisms from top to bottom, namely a cleaning mechanism at the top, a water receiving mechanism at the middle and a drainage mechanism at the bottom; the positions of the cleaning mechanism and the drainage mechanism are in a fixed vertical alignment state, and the water receiving mechanism is arranged on a rotating disc; when the injection and suction liquid needles are used, the water receiving mechanism is vertically aligned with the cleaning mechanism and the drainage mechanism through rotation of the rotating disc, so that the injection and suction liquid needles are cleaned by the cleaning mechanism; and the cleaned cleaning water is sequentially discharged from the cleaning disc through the water receiving mechanism and the drainage mechanism. The application can simplify the cleaning steps of the injection and suction liquid needles when the injection and suction liquid needles are cleaned.

Description

Technical Field

[0001] This invention relates to a method for cleaning needles, and more particularly to a method for cleaning the injection and aspiration needles of the cleaning tray in a fully automated single-molecule immunoassay analyzer, belonging to the field of medical testing technology. Background Technology

[0002] Since the first automated chemical analysis instrument was manufactured, more than half a century has passed, and fully automated immunoassay analyzers have reached a high level of technological maturity. Modern fully automated immunoassay analyzers possess the following characteristics: 1. They employ multi-degree-of-freedom robotic arms to coordinate the movements of various modules; 2. The instruments are highly flexible, meeting diverse analytical needs; 3. They offer fast testing speeds and long continuous operation times without human intervention; 4. They combine multiple technologies in detection and fully automate processing, resulting in more accurate and precise test results. Fully automated immunoassay analyzers can handle steps such as taking reaction cups, adding samples, adding reaction solutions, shaking, promoting the reaction, measuring, calculating and analyzing, and cleaning during experimental testing. Replacing manual operation not only saves labor costs but, more importantly, eliminates human error, ensuring data accuracy. With advantages such as speed, efficiency, high precision, and repeatability, fully automated immunoassay analyzers are widely used in processing, production, testing, and daily life assistance, and are poised to become a trend in the medical testing field.

[0003] During the testing process, magnetic nanobeads are used to bind with antibodies and antigens. After binding, the remaining liquid in the reaction vessel needs to be washed to ensure detection efficiency. The principle of magnetic separation and washing is as follows: In the principle of enzyme-catalyzed chemiluminescent immunoassay, the clonal antibody in the magnetic bead reagent reacts with the analyte in the sample, as well as the enzyme-labeled antibody or antigen in the reagent, through a non-specific immune reaction, forming a magnetic immune complex that can be suspended in the reaction system. In the magnetic field formed by the magnet, the magnetic immune complex and unbound magnetic particles are rapidly captured by the magnetic field and attached to the part near the magnetic field. The liquid outside the magnetic particle complex is removed, thus separating the magnetic particle complex from the enzyme particles in the liquid. When the external magnetic field is removed and washing solution is injected, the magnetic particle complex can be uniformly dispersed in the solution again. Repeating this process multiple times completes the washing of free enzymes. As a reaction carrier for antigens and antibodies, the suspendable property of the magnetic beads allows the immune reaction to occur rapidly under uniform conditions, while also promoting the rapid separation of the immune complex from the solution.

[0004] In immunoassay analyzers, the cleaning tray is responsible for cleaning the reaction cups. During the cleaning process, the reaction cups undergo repeated "liquid injection cleaning - liquid aspiration discharge" until they are sent to the next process for testing. A problem with existing technology is that after a period of downtime, the injection and aspiration needles in the cleaning tray need to be cleaned. Current cleaning trays can only use the injection and aspiration needles to clean the magnetic beads in the reaction cups. Cleaning the injection and aspiration needles themselves is cumbersome and ineffective.

[0005] The applicant filed an invention patent application in 2023, publication number CN116984298A, publication date November 3, 2023. This patent document discloses a method for cleaning the injection and aspiration needles in the cleaning tray of an immunoassay analyzer. The method involves setting a cleaning tank inside the cleaning tray below the turntable. During normal operation, the injection and aspiration needles are controlled to move down and insert into the reaction cup on the turntable for cleaning. When it is necessary to clean the injection and aspiration needles, the reaction cup is removed first, and then the injection and aspiration needles are controlled to move down so that they pass through the turntable and are inserted into the cleaning tank for cleaning.

[0006] In this patent document, both the injection needle and the aspiration needle are mounted on the needle body lifting mechanism. When cleaning the injection needle and the aspiration needle, it is necessary to control both the injection needle and the aspiration needle to move down and insert into the cleaning tank for cleaning. Therefore, the cleaning steps for the injection needle and the aspiration needle are relatively complicated.

[0007] Therefore, how to redesign a cleaning method for injection and aspiration needles in a cleaning tray, so as to simplify the cleaning steps of injection and aspiration needles, is an urgent technical problem to be solved. Summary of the Invention

[0008] The technical problem to be solved by the present invention is to address the deficiencies in the prior art by providing a cleaning method for the injection and aspiration needles of a cleaning tray, which simplifies the cleaning steps of the injection and aspiration needles.

[0009] To solve the above-mentioned technical problems, the technical solution adopted by the present invention is as follows: a method for cleaning the injection and aspiration needles of a cleaning tray, wherein the cleaning tray is designed with three mechanisms from top to bottom: a cleaning mechanism at the top, a water receiving mechanism in the middle, and a drainage mechanism at the bottom; the cleaning mechanism and the drainage mechanism are in a fixed vertical alignment state, and the water receiving mechanism is set on a turntable; when injecting or aspirating the needles, the rotation of the turntable makes the water receiving mechanism, the cleaning mechanism, and the drainage mechanism vertically aligned, thereby using the cleaning mechanism to clean the injection and aspiration needles, and the cleaning water after cleaning passes through the water receiving mechanism and the drainage mechanism in sequence before being discharged from the cleaning tray.

[0010] Preferably, the upper cleaning mechanism refers to a cleaning cylinder that works with the suction needle for cleaning, and an injection needle that is separately installed on the top of the cleaning plate located between the needle lifting mechanism and the turntable; the middle water receiving mechanism refers to a water receiving cylinder installed on the turntable, the number of which is the same as the number of suction needles and injection needles; the lower drainage mechanism refers to a drainage cylinder installed in the lower part of the cleaning plate, the number of which is also the same as the number of suction needles and injection needles.

[0011] Preferably, the injection needle adopts a modular design. The modular injection needle includes a needle seat body with an internal solenoid valve and a tube body disposed at the bottom of the needle seat body. The tube body is connected to an external liquid supply system through the solenoid valve. The modular injection needle is installed on the top of the cleaning disc cylinder by connecting the needle seat body to the cleaning disc cylinder.

[0012] Preferably, a tube through hole is provided on the top of the cleaning disc cylinder. When the needle seat of the modular injection needle is installed on the top of the cleaning disc cylinder, the tube is inserted into the tube through hole.

[0013] Preferably, the cleaning cylinder includes a cleaning cylinder body, and a water inlet channel is provided on the side of the cleaning cylinder body. The water inlet pipe is connected to the inner cavity of the cleaning cylinder body through the water inlet channel.

[0014] Preferably, a cylinder through hole is also provided on the top of the cleaning disc cylinder, and when the cleaning cylinder is installed on the top of the cleaning disc cylinder, the inner cavity of the cylinder is connected to the cylinder through hole.

[0015] Preferably, when cleaning the injection needle, first control the turntable to rotate so that the tube of the modular injection needle, the water receiving cylinder on the turntable, and the drain cylinder inside the cleaning disc are aligned vertically. Then control the solenoid valve to activate, so that external cleaning water is injected into the water receiving cylinder through the tube, then flows from the water receiving cylinder into the drain cylinder, and finally discharged.

[0016] Preferably, when cleaning the inner wall of the suction needle, first control the turntable to rotate so that the cylinder through hole on the top of the cleaning cylinder, the water receiving cylinder on the turntable, and the drain cylinder inside the cleaning cylinder are vertically aligned. Then, control the cleaning water to enter the inner cavity of the cleaning cylinder from the inlet pipe, and then flow into the water receiving cylinder through the inner cavity and the cylinder through hole, and then flow from the water receiving cylinder into the drain cylinder, and finally discharge.

[0017] Preferably, when cleaning the outer wall of the suction needle, the turntable is first rotated so that the cylinder through hole on the top of the cleaning cylinder, the water receiving cylinder on the turntable, and the drain cylinder inside the cleaning cylinder are vertically aligned. Then, the cleaning water is controlled to enter the inner cavity of the cleaning cylinder from the inlet pipe, and then flows into the water receiving cylinder through the inner cavity and the cylinder through hole, and then flows into the drain cylinder from the water receiving cylinder, and finally is discharged. After the cleaning water enters the cleaning cylinder, the suction needle inserted into the inner cavity of the cylinder is controlled to move up and down back and forth in the inner cavity of the cylinder, so as to use the cleaning water in the inner cavity of the cylinder to clean the outer wall of the suction needle.

[0018] Preferably, when cleaning the outer wall of the aspiration needle, the length of cleaning the outer wall of the aspiration needle is determined by controlling the up and down stroke of the aspiration needle.

[0019] The beneficial effects of this invention are as follows: By setting up a cleaning mechanism at the top, a water receiving mechanism in the middle, and a drainage mechanism at the bottom, the invention utilizes the cooperation of these three mechanisms to ensure the normal operation of the detection process and greatly simplify the cleaning steps for the injection and aspiration needles. By moving the cleaning mechanism upwards, compared with existing technologies, the length of the injection and aspiration needles and their downward travel are shortened during the cleaning operation, thereby reducing the probability of factors affecting the detection operation. When cleaning the outer wall of the aspiration needle, the length of cleaning is controlled by adjusting the upward and downward travel of the needle, allowing the invention to select the cleaning length according to actual working conditions, thus enhancing its practicality. Attached Figure Description

[0020] Figure 1 This is a three-dimensional structural diagram of the cleaning disc in an embodiment of the present invention; Figure 2 This is a schematic diagram of the axial cross-sectional structure of the cleaning disc in an embodiment of the present invention; Figure 3 This is a three-dimensional structural diagram of the modular injection needle in an embodiment of the present invention; Figure 4 This is a partial axial cross-sectional view of the modular injection needle after it has been installed on the top of the cleaning disc cylinder in an embodiment of the present invention. Figure 5 This is a partial axial cross-sectional view of the cleaning cylinder after it has been installed on the top of the cleaning tray body in an embodiment of the present invention. Figure 6 A partial axial cross-sectional view of the cleaning cylinder in this embodiment of the invention during normal testing. Figure 7 This is a three-dimensional structural diagram of a turntable with a water receiving tube in an embodiment of the present invention; Figure 8This is a partial three-dimensional structural diagram of the drain cylinder after it is installed inside the cleaning disc cylinder in an embodiment of the present invention. Figure 9 This is a schematic diagram illustrating the principle and structure of cleaning the inner wall of the injection needle in an embodiment of the present invention. Figure 10 This is a schematic diagram illustrating the principle structure of cleaning the inner wall of the aspiration needle in an embodiment of the present invention. Figure 11 This is a schematic diagram illustrating the principle and structure of cleaning the outer wall of the aspiration needle in an embodiment of the present invention. Figure 1 ; Figure 12 This is a schematic diagram illustrating the principle and structure of cleaning the outer wall of the aspiration needle in an embodiment of the present invention. Figure 2 .

[0021] In the diagram: 1. Cleaning disc cylinder, 111. Tube through hole, 112. Cylinder through hole, 1121. Conical hole, 2. Turntable mechanism, 211. Turntable, 3. Needle lifting mechanism, 4. Reaction cup, 5. Cleaning cylinder, 511. Cleaning cylinder body, 512. Water inlet channel, 513. Cylinder inner cavity, 514. Annular cavity, 6. Injection needle, 611. Needle seat body, 612. Tube body, 7. Suction needle, 8. Water inlet pipe, 9. Water receiving cylinder, 911. Upper water receiving cylinder, 912. Lower water receiving cylinder, 10. Drain cylinder. Detailed Implementation

[0022] The applicant's research revealed that during routine cleaning of magnetic beads in reaction cups using a cleaning tray, when injecting liquid into the reaction cup using a syringe needle, only the inner wall of the needle needs to be cleaned since the needle is already submerged. However, when aspirating liquid is drawn from the reaction cup using a suction needle, both the inner and outer walls of the needle must be cleaned. Therefore, cleaning the syringe needle involves injecting cleaning water from the outside, with the flowing water cleaning the inner wall of the syringe. In contrast, the suction needle needs to be inserted into a cleaning container, such as a cleaning tank, to draw out cleaning water, which is then used to clean both the inner and outer walls of the suction needle.

[0023] Therefore, considering the cleaning characteristics of the injection needle and the aspiration needle, the injection needle does not need to move up and down with the needle body lifting mechanism. Since the cleaning water for the injection needle comes from the outside, it only needs to consider how to drain the externally injected cleaning water. The aspiration needle, on the other hand, needs to move up and down with the needle body lifting mechanism to be inserted into the cleaning container for cleaning, but it also needs to consider the problem of draining the cleaning water from the cleaning container.

[0024] Therefore, in order to simplify the cleaning process of the injection needle and the aspiration needle, the applicant designed the injection needle and the aspiration needle separately. The injection needle is fixed on the top of the cleaning tray, while the aspiration needle is still set on the needle lifting mechanism. The next step is to address the issue of draining the cleaning water. To simplify the cleaning structure and process, if the cleaning water for cleaning the injection needle and the cleaning water for cleaning the aspiration needle can be drained together, the cleaning structure and process can be simplified to the greatest extent. Therefore, the applicant designed three mechanisms on the cleaning tray from top to bottom: a cleaning mechanism at the top, a water receiving mechanism in the middle, and a drainage mechanism at the bottom.

[0025] The cleaning mechanism located above refers to the cleaning cylinder positioned at the top of the cleaning disc between the needle lifting mechanism and the turntable. During normal testing, the aspiration needle descends with the needle lifting mechanism, passes through the cleaning cylinder, and inserts into the reaction cup on the turntable. When cleaning the aspiration needle, it descends with the needle lifting mechanism and inserts into the cleaning cylinder for cleaning. The injection needle is fixed to the top of the cleaning disc. During normal testing, the injection needle injects liquid into the reaction cup on the turntable. When cleaning the injection needle, external cleaning water is directly drawn in and injected. Thus, the cleaning positions for the injection needle and aspiration needle are located at the top of the cleaning disc.

[0026] The water receiving mechanism located in the middle refers to a water receiving tube installed on the turntable. The water receiving tube is used to collect the cleaning water discharged from the upper cleaning mechanism after cleaning the injection needle and the washing needle, and to guide the cleaning water after cleaning to the drainage mechanism located below.

[0027] The drainage mechanism located below refers to a drainage cylinder located inside the cleaning pan and below the turntable. The drainage cylinder is used to drain the cleaning water that has been collected in the water tank and discharged it outside the cleaning pan.

[0028] Based on the above design concept, this invention utilizes the different cleaning characteristics of injection needles and aspiration needles to greatly simplify the cleaning steps of injection needles and aspiration needles.

[0029] The technical solution of the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0030] Example: Figure 1 and Figure 2As shown, the cleaning tray includes a cleaning tray body 1, a turntable mechanism 2 disposed inside the cleaning tray body 1, and a needle lifting mechanism 3 disposed above the cleaning tray body 1. A reaction cup 4 is placed on the turntable 211 of the turntable mechanism 2, and the turntable 211 drives the reaction cup 4 to rotate. A cleaning cylinder 5 is disposed on the top of the cleaning tray body 1 and below the needle lifting mechanism 3. An injection needle 6 is fixedly disposed on the top of the cleaning tray body 1, and an aspiration needle 7 is disposed on the needle lifting mechanism 3. In this embodiment, three injection needles 6 and three aspiration needles 7 are provided, for a total of six. To simplify the cleaning steps and structure, the injection needles 6 and aspiration needles 7 are not installed together on the needle lifting mechanism 3, but are installed separately. It should also be noted that in this embodiment, only the aspiration needle 7 retains the needle-like structure as before. The injection needle 6 in this embodiment adopts a modular design, no longer using a needle body like the aspiration needle 7. This is because previously, during operation, the needles had to be inserted downwards into the reaction cup. The more needles there were, the higher the requirement for concentricity among the multiple needles, otherwise some needles would hit the reaction cup wall during insertion. In this embodiment, the injection needle 6 adopts a modular design, retaining only the needle body structure of the aspiration needle 7, thus reducing the total number of needles and lessening the requirement for needle concentricity. Furthermore, the modular design of the injection needle 6 facilitates disassembly and assembly. The number of cleaning cylinders 5 is the same as the number of aspiration needles 7, with three cylinders provided to facilitate needle cleaning in conjunction with the aspiration needles 7.

[0031] The cleaning mechanism located at the top, the water receiving mechanism located in the middle, and the drainage mechanism located at the bottom will be described in detail below: 1. The cleaning mechanism located at the top: 1. Describe the structure and location of the modular injection needle 6: like Figure 3 and Figure 4 As shown, the modular injection needle 6 includes a needle seat 611 with an internal solenoid valve and a tube 612 located at the bottom of the needle seat 611. The tube 612 is connected to an external liquid supply system via the solenoid valve. A tube through-hole 111 is opened on the top of the cleaning disc cylinder 1. When the needle seat 611 of the modular injection needle is installed on the top of the cleaning disc cylinder 1, the tube 612 is inserted into the tube through-hole 111. During normal testing operations, it is used to inject liquid into the reaction cup located on the turntable below. At this time, a gap is left between the bottom of the tube 612 and the reaction cup 4, and it is no longer inserted into the reaction cup for liquid injection as before. This further reduces the possibility of contamination of the modular injection needle 6. The inner diameter of the tube 612 is smaller than the diameter of the reaction cup 4, which facilitates the injection of reagent from the tube 612 into the reaction cup 4 without leakage elsewhere.

[0032] 2. Describe the structure and location of the cleaning cylinder 5: like Figure 1 , Figure 5 and Figure 6 As shown, the cleaning cylinder 5 includes a cleaning cylinder body 511. A water inlet channel 512 is provided on the side of the cleaning cylinder body 511, and a water inlet pipe 8 is connected to the inner cavity 513 of the cleaning cylinder body 511 through the water inlet channel 512. A cylinder through hole 112 is also provided on the top of the cleaning disc cylinder 1. When the cleaning cylinder body 511 is installed on the top of the cleaning disc cylinder 1, the inner cavity 513 of the cylinder is connected to the cylinder through hole 112. During normal testing, the aspiration needle 7 can be inserted into the reaction cup 4 below through the inner cavity 513 and the cylinder through hole 112. When cleaning the aspiration needle 7, external cleaning water is sent into the inner cavity 513 of the cylinder through the water inlet pipe 8, and then the aspiration needle 7 is controlled to be inserted into the inner cavity 513 of the cylinder for cleaning.

[0033] like Figure 5 As shown, an annular cavity 514 is also provided inside the cleaning cylinder 511. The water inlet channel 512 is connected to the annular cavity 514, and the annular cavity 514 is connected to the inner cavity 513 of the cylinder through a spray hole 515. In this way, when cleaning the outer wall of the suction needle 7, the cleaning water can be sprayed onto the outer wall of the suction needle 7 using the spray hole 515, further improving the cleaning effect. Multiple spray holes 515 can be provided. A conical hole 1121 is provided at the upper end of the cylinder through hole 112. The large end of the conical hole 1121 is connected to the inner cavity 513 of the cylinder. Here, the conical hole 1121 cooperates with the inner cavity 513 of the cylinder to alleviate the downward flow of cleaning water. When external cleaning water is continuously supplied, a certain amount of cleaning water can be retained in the inner cavity 513 of the cylinder during the cleaning process, thereby facilitating further cleaning of the suction needle 7.

[0034] II. The water receiving mechanism located in the middle: like Figure 7 As shown, water receiving tubes 9 are arranged on the turntable 211, and their number and position correspond to the number and position of the modular injection needles 6 and suction needles 7. In this embodiment, since there are three modular injection needles 6 and three suction needles 7, six water receiving tubes 9 are also provided. Each water receiving tube 9 includes an upper water receiving tube 911 and a lower water receiving tube 912 connected to the upper water receiving tube 911. The diameter of the upper water receiving tube 911 is larger than the diameter of the tube body 612 of the modular injection needle 6. This facilitates the flow of cleaning water from the tube body 612 into the water receiving tube 9 when cleaning the injection needle 6, preventing leakage elsewhere. The diameter of the upper water receiving tube 911 is also larger than the diameter of the tube through hole 112 on the top of the cleaning disc tube 1. This also facilitates the flow of cleaning water from the tube through hole 112 into the water receiving tube 9 when cleaning the suction needle 7, preventing leakage elsewhere.

[0035] III. Drainage mechanism located below: like Figure 8 As shown, a drain cylinder 10 is installed inside the cleaning tray cylinder 1 and below the turntable 211. The number and position of the drain cylinders 10 correspond to the number and position of the modular injection needles 6 and suction needles 7. Therefore, in this embodiment, six drain cylinders 10 are provided. The diameter of the drain cylinder 10 is larger than the diameter of the lower end water receiving cylinder 912 of the water receiving cylinder 9, thereby ensuring that the cleaning water flowing out of the lower end water receiving cylinder 912 flows into the drain cylinder 10 and does not leak elsewhere. Multiple drain cylinders 10 discharge the cleaning water to the outside of the cleaning tray.

[0036] like Figure 4 and Figure 6 As shown, in this embodiment, during the normal detection injection operation, the turntable 211 is first controlled to rotate so that the reaction cup 4 on the turntable 211 is aligned with the tube 612 of the modular injection needle 6. Then, the solenoid valve is controlled to actuate so that the external reagent is injected into the reaction cup 4 through the tube 612. After the injection is completed, the solenoid valve is controlled to actuate again so that the tube 612 stops injecting liquid.

[0037] During the normal liquid aspiration operation, first control the turntable 211 to rotate so that the reaction cup 4 on the turntable 211 is aligned with the through hole 112 of the cleaning disc cylinder 1. Then control the needle lifting mechanism 3 to move, causing the aspiration needle 7 to descend. The aspiration needle 7 passes through the inner cavity 513 of the cleaning cylinder 5 and the through hole 112 of the cleaning disc cylinder 1 in sequence before being inserted into the reaction cup 4 for liquid aspiration. After the liquid aspiration is completed, control the needle lifting mechanism 3 to move again, causing the aspiration needle 7 to rise and be pulled out of the reaction cup 4.

[0038] like Figure 9 As shown, in this embodiment, when cleaning the injection needle 6, the turntable 211 is first rotated so that the tube 612 of the modular injection needle 6, the water receiving cylinder 9 on the turntable 211, and the drain cylinder 10 inside the cleaning disc 1 are vertically aligned, i.e., at the same axis position. Then, the solenoid valve is activated so that external cleaning water is injected into the water receiving cylinder 9 through the tube 612, then flows from the water receiving cylinder 9 into the drain cylinder 10, and finally discharged (as shown by the hollow arrow in the figure). The cleaning water passing through the tube 612 is used to clean the inner wall of the modular injection needle 6.

[0039] like Figure 10As shown, in this embodiment, when cleaning the inner wall of the suction needle 7, the turntable 211 is first controlled to rotate so that the cylinder through hole 112 on the top of the cleaning cylinder 1, the water receiving cylinder 9 on the turntable 211, and the drain cylinder 10 inside the cleaning cylinder 1 are aligned vertically, that is, at the same axis position. Then, the cleaning water is controlled to enter the inner cavity 513 of the cleaning cylinder 5 from the water inlet pipe 8, and then flows into the water receiving cylinder 9 through the inner cavity 513 and the cylinder through hole 112, and then flows into the drain cylinder 10 from the water receiving cylinder 9, and finally discharged (as shown by the hollow arrow in the figure). When the cleaning water enters the cleaning cylinder 5, the suction needle 7 inserted into the inner cavity 513 of the cylinder is controlled to draw up the cleaning water (as shown by the solid arrow in the figure), thereby using the cleaning water that has passed through the inner wall of the suction needle 7 to clean the inner wall of the suction needle 7.

[0040] like Figure 11 and Figure 12 As shown, when cleaning the outer wall of the suction needle 7, the turntable 211 is first rotated so that the cylinder through hole 112 on the top of the cleaning cylinder 1, the water receiving cylinder 9 on the turntable 211, and the drain cylinder 10 inside the cleaning cylinder 1 are aligned vertically, i.e., at the same axis position. Then, the cleaning water is controlled to enter the inner cavity 513 of the cleaning cylinder 5 from the water inlet pipe 8, and then flows into the water receiving cylinder 9 through the inner cavity 513 and the cylinder through hole 112, and then flows into the drain cylinder 10 from the water receiving cylinder 9, and finally discharged (as shown by the hollow arrow in the figure). After the cleaning water enters the cleaning cylinder 5, the suction needle 7 inserted into the inner cavity 513 is controlled to move up and down back and forth in the inner cavity 513 (as shown by the solid arrow in the figure), so as to use the cleaning water in the inner cavity 513 to clean the outer wall of the suction needle 7.

[0041] It should be noted that in this embodiment, the cleaning of the inner and outer walls of the aspiration needle is generally carried out separately. This is because when cleaning the outer wall of the needle, it is necessary to control the aspiration needle to stop aspirating, so as to avoid some of the cleaning water and air in the cylinder cavity being drawn away by the aspiration needle during the up and down movement of the aspiration needle.

[0042] In this embodiment, the cleaning of the outer wall of the suction needle is carried out by controlling the repeated up and down movement of the suction needle in conjunction with the cleaning water. This allows the length of cleaning the outer wall of the suction needle to be determined by controlling the stroke of the suction needle's up and down movement. As a result, this embodiment can select the cleaning length of the outer wall of the suction needle according to the actual working conditions, making it more practical.

[0043] In summary, this invention, by setting up a cleaning mechanism at the top, a water receiving mechanism in the middle, and a drainage mechanism at the bottom, utilizes the cooperation of these three mechanisms to ensure the normal operation of the testing process while greatly simplifying the cleaning steps for the injection and aspiration needles. By moving the cleaning mechanism upwards, compared with existing technologies, the length of the injection and aspiration needles and their downward travel are shortened during the cleaning operation, thereby reducing the probability of factors affecting the testing operation. When cleaning the outer wall of the aspiration needle, the length of cleaning is controlled by controlling the upward and downward travel of the aspiration needle, allowing the invention to select the cleaning length of the outer wall of the aspiration needle according to actual working conditions, thus enhancing its practicality.

[0044] In this embodiment, "multiple" refers to "two or more". The above embodiments are for illustrative purposes only and are not intended to limit the invention. Those skilled in the art can make various changes or modifications without departing from the spirit and scope of the invention. Therefore, all equivalent technical solutions should also fall within the protection scope of this invention, which is defined by the claims.

Claims

1. A method for cleaning the injection and aspiration needles of a cleaning tray, characterized in that: The cleaning tray is designed with three mechanisms from top to bottom: a cleaning mechanism at the top, a water receiving mechanism in the middle, and a draining mechanism at the bottom. The cleaning and draining mechanisms are in a fixed vertical alignment, and the water receiving mechanism is set on a turntable. When injecting or aspirating the liquid needle, the rotation of the turntable makes the water receiving mechanism, cleaning mechanism, and draining mechanism vertically aligned, so that the cleaning mechanism can clean the injection or aspiration needle. The cleaning water passes through the water receiving and draining mechanisms in sequence and is discharged from the cleaning tray. The upper cleaning mechanism refers to a cleaning cylinder that works with the suction needle for cleaning, and an injection needle that is separately installed on the top of the cleaning plate located between the needle lifting mechanism and the turntable; the middle water receiving mechanism refers to a water receiving cylinder installed on the turntable, and the number of the water receiving cylinders is the same as the number of suction needles and injection needles; the lower drainage mechanism refers to a drainage cylinder installed in the lower part of the cleaning plate, and the number of the drainage cylinders is also the same as the number of suction needles and injection needles.

2. The cleaning method according to claim 1, characterized in that: The injection needle adopts a modular design. The modular injection needle includes a needle seat body with an internal solenoid valve and a tube body located at the bottom of the needle seat body. The tube body is connected to an external liquid supply system through the solenoid valve. The modular injection needle is installed on the top of the cleaning disc cylinder by connecting the needle seat body to the cleaning disc cylinder.

3. The cleaning method according to claim 2, characterized in that: A tube through hole is opened on the top of the cleaning disc cylinder. When the needle seat of the modular injection needle is installed on the top of the cleaning disc cylinder, the tube is inserted into the tube through hole.

4. The cleaning method according to claim 3, characterized in that: The cleaning cylinder includes a cleaning cylinder body, and a water inlet channel is provided on the side of the cleaning cylinder body. The water inlet pipe is connected to the inner cavity of the cleaning cylinder body through the water inlet channel.

5. The cleaning method according to claim 4, characterized in that: A cylinder through hole is also provided on the top of the cleaning disc cylinder. When the cleaning cylinder is installed on the top of the cleaning disc cylinder, the inner cavity of the cylinder is connected to the cylinder through hole.

6. The cleaning method according to claim 5, characterized in that: When cleaning the injection needle, first control the turntable to rotate so that the tube of the modular injection needle, the water receiving cylinder on the turntable, and the drain cylinder inside the cleaning disc are vertically aligned. Then control the solenoid valve to activate, so that the external cleaning water is injected into the water receiving cylinder through the tube, then flows from the water receiving cylinder into the drain cylinder, and finally discharged.

7. The cleaning method according to claim 5, characterized in that: When cleaning the inner wall of the suction needle, first control the turntable to rotate so that the cylinder through hole on the top of the cleaning cylinder, the water receiving cylinder on the turntable, and the drain cylinder inside the cleaning cylinder are vertically aligned. Then, control the cleaning water to enter the inner cavity of the cleaning cylinder from the inlet pipe, and then flow into the water receiving cylinder through the inner cavity and the cylinder through hole, and then flow from the water receiving cylinder into the drain cylinder, and finally be discharged.

8. The cleaning method according to claim 5, characterized in that: When cleaning the outer wall of the suction needle, first control the turntable to rotate so that the cylinder through hole on the top of the cleaning cylinder, the water receiving cylinder on the turntable, and the drain cylinder inside the cleaning cylinder are vertically aligned. Then, control the cleaning water to enter the inner cavity of the cleaning cylinder from the inlet pipe, and then flow into the water receiving cylinder through the inner cavity and the cylinder through hole, and then flow into the drain cylinder from the water receiving cylinder, and finally discharge. After the cleaning water enters the cleaning cylinder, control the suction needle inserted into the inner cavity of the cylinder to move up and down back and forth in the inner cavity of the cylinder, so as to use the cleaning water in the inner cavity of the cylinder to clean the outer wall of the suction needle.

9. The cleaning method according to claim 8, characterized in that: When cleaning the outer wall of the suction needle, the length of cleaning is determined by controlling the up and down stroke of the suction needle.

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