A volatile oil of wulili bahan san and a preparation method thereof, a traditional Chinese medicine extract and a pharmaceutical preparation

By extracting the volatile oil of Wuli Bahan San through low-temperature pulverization and heating reflux, and controlling the quality by gas chromatography-mass spectrometry, the adverse reactions caused by inaccurate use of Wuli Bahan San were resolved, thus improving the safety and efficacy of the drug.

CN118987098BActive Publication Date: 2026-06-30BEIJING TONGRENTANG CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIJING TONGRENTANG CO LTD
Filing Date
2024-07-05
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

The current clinical dosage of Wulibahansan is unclear and the concentration is inaccurate, resulting in a large number of adverse clinical reactions and prominent drug safety issues.

Method used

The volatile oil of Wuli Bahan San was prepared by using a low-temperature pulverization method of mixed medicinal materials of white rapeseed and green Sichuan pepper, combined with the method of heating and reflux extraction of volatile oil. The quality control was carried out by gas chromatography-mass spectrometry to prepare a pharmaceutical preparation to reduce irritation.

Benefits of technology

It significantly reduces the side effects of the drug, improves its efficacy, and has good effects in dispelling wind and cold, promoting blood circulation and unblocking collaterals, while reducing skin irritation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to the field of traditional Chinese medicine preparations, and specifically provides a volatile oil of Wuli Baohan Powder, a preparation method thereof, a traditional Chinese medicine extract, and a pharmaceutical preparation. The preparation method includes the following steps: Step S1: Take Cleome gynandra seeds, crush them below 60°C, and mix them with crushed Zanthoxylum schinifolium to obtain a mixed medicinal material; Step S2: Take the mixed medicinal material obtained in Step S1, soak it in water at 4-40°C, heat under reflux, and collect the volatile oil of Wuli Baohan Powder; Through low-temperature (below 60°C) crushing of Cleome gynandra seeds, combined with the volatile oil of Wuli Baohan Powder extracted by soaking at 4-40°C (room temperature) before heating under reflux extraction, there are obvious differences in chemical components from the volatile oil obtained from samples that are not crushed or conventionally crushed or directly treated at high temperature. The side effects of the prepared pharmaceutical preparation are significantly reduced, and at the same time, it has good curative effects of dispelling wind and cold, promoting blood circulation and dredging collaterals.
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