基于状态空间对偶的病理图像分类方法

By using the Mamba2MIL model, which combines state-space duality and multi-instance learning, the problems of low efficiency and error susceptibility in pathological image analysis are solved, achieving efficient whole-slice image classification and improving the accuracy and efficiency of pathological image analysis.

CN119048825BActive Publication Date: 2026-07-17BEIHANG UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIHANG UNIV
Filing Date
2024-08-23
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Traditional pathological image analysis is inefficient and error-prone, especially the challenge of automating the analysis of whole-slice images (WSIs).

Method used

By employing the Mamba2MIL model and combining state-space duality (SSD) and multi-instance learning methods, a novel multi-instance learning framework is designed to handle sequential dependencies and independent features in pathological images through sequence enhancement and feature weighted selection. This framework adapts to sequence transformations of different WSI sizes and enhances classification capabilities.

Benefits of technology

It significantly improves the classification accuracy and analysis efficiency of pathological images, reduces computational complexity, effectively processes long sequence data, and provides more discriminative feature representations.

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Abstract

本发明提出基于状态空间对偶性(SSD)的计算病理学多实例学习(MIL)方法,提出了一种新型的Mamba2MIL模型,该模型能够综合利用WSIs中的顺序依赖和顺序独立特征,以提高病理图像的分类准确性。本发明涉及计算病理学领域,特别是一种基于状态空间对偶性(State Space Duality,SSD)的多实例学习方法,用于全切片图像(Whole Slide Images,WSIs)的自动分析与诊断。本发明属于图像数据处理(G06T)及医学诊断(A61B)领域。该模型通过预处理、特征提取、序列化处理、状态空间对偶模型的应用,最终通过多层感知器进行分类决策,有效处理了长序列数据并提高了诊断的准确性。实验证明Mamba2MIL方法在提高病理图像分析效率和诊断准确性方面具有重要应用价值,为病理学家提供了一个有价值的辅助工具,具有广阔的临床应用前景。
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