一株白马拟无枝酸菌潜在新种(Amycolatopsis baimaensis)WQ 127309及其应用

The isolation and identification of a new species of Amylopectinus baimai WQ 127309 has solved the problems of existing antibiotic resistance and insufficient development of antitumor drugs, and provided new antibiotics and drug resources with broad-spectrum antibacterial and antitumor activities.

CN119060905BActive Publication Date: 2026-07-17YUNNAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
YUNNAN UNIV
Filing Date
2024-09-30
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

The widespread use of existing antibiotics has led to increased bacterial resistance, slowed down the development of new antibiotics, and the secondary metabolites of Amylopectinobacterium have not been fully explored, resulting in a lack of effective broad-spectrum antibacterial and antitumor active substances.

Method used

A novel species of Amycolatopsis, Amycolatopsis baimaensis WQ 127309, was isolated and identified. Its cells and metabolites were obtained by culturing in culture medium and showed inhibitory activity against a variety of bacteria and tumor cells.

Benefits of technology

The white horse amycotic acid bacterium WQ 127309 has shown significant inhibitory activity against a variety of bacteria and tumor cells, possessing broad-spectrum antibacterial and antitumor potential, and providing a new resource for antibiotics and antitumor drugs.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开了一株白马拟无枝酸菌潜在新种(Amycolatopsis baimaensis)WQ 127309及其应用。本发明提供的拟无枝酸菌WQ 127069已保藏于中国典型培养物保藏中心,保藏编号为CCTCC M 20241536。该菌株具有显著广谱抑制革兰氏阳性菌(金黄色葡萄球菌、枯草芽孢杆菌、结核分枝杆菌、粪肠球菌、和藤黄八叠球菌)、革兰氏阴性菌(大肠杆菌、奇异变形杆菌和铜绿假单孢菌)和真菌(白色念珠菌)的作用,同时该菌株对HepG 2和Hela细胞增殖具有很强的抑制作用,为抗生素及抗肿瘤药物的研制与应用提供菌种资源及理论依据,具有较好的市场应用前景。
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