Anti-aging efficacy of cyclic dipeptides and uses thereof

CN119112699BActive Publication Date: 2026-06-30SHANGHAI JAHWA UNITED
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI JAHWA UNITED
Filing Date
2024-09-14
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

Existing peptide-based cosmetics have low transdermal absorption rates, are easily degraded by proteases, resulting in low bioavailability, and lack the ability to effectively promote the production of collagen and elastin.

Method used

Cyclic (L-leucine-L-proline) dipeptide is used as an anti-aging ingredient, which promotes the production of type I collagen, fibronectin, core proteoglycan Decorin and elastin, and is used in cosmetics and pharmaceuticals.

Benefits of technology

It improves skin firmness, reduces wrinkles and sagging, enhances the skin's self-protection ability, and reduces signs of skin aging.

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Abstract

This invention provides the anti-aging application of cyclic dipeptides, wherein the cyclic dipeptides are cyclic (L-leucine-L-proline) dipeptides. The anti-aging effect of this invention is achieved by promoting type I collagen, fibronectin, core proteoglycan Decorin, and / or elastin, or by inhibiting advanced glycation end products (AGEs). This invention also relates to the application of cyclic dipeptides in the preparation of topical skin agents or pharmaceuticals with anti-aging effects, wherein the topical skin agents are selected from: creams, lotions, gels, toners, serums, masks, eye creams, aerosol cleansing foams, sprays, shower gels, or facial cleansers.
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