工程化核酸酶、组合物及其使用方法
By deleting and modifying the amino acid sequence of the Cas protein, smaller engineered nuclease variants were developed, overcoming the size limitations of existing nucleases, enabling efficient target gene editing and regulation, and improving the delivery capability of gene therapy.
CN119137268BActive Publication Date: 2026-07-17EPICRISPR BIOTECHNOLOGIES INC
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- EPICRISPR BIOTECHNOLOGIES INC
- Filing Date
- 2023-03-01
- Publication Date
- 2026-07-17
Smart Images
Figure CN119137268B_ABST
Abstract
本公开提供了一种或多种工程化核酸酶及其系统、组合物和方法，其中所述一种或多种工程化核酸酶可用于实现对靶多核苷酸序列进行结合、切割和 / 或编辑。所述一种或多种工程化核酸酶可以是小CRISPR / Cas蛋白的工程化变体。
Need to check novelty before this filing date? Find Prior Art