一种血管内生物可吸收纯镁支架的制备方法

By processing pure magnesium material through a combination of equal channel angle pressing and high-pressure torsional extrusion, and then performing laser engraving and plasma chemical vapor deposition, a bioresorbable pure magnesium stent suitable for intravascular use was prepared. This solved the problem of insufficient physical properties of pure magnesium material and enabled the application of high-performance stents.

CN119141153BActive Publication Date: 2026-07-17JIANGSU XIANGLAN MEDICAL TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JIANGSU XIANGLAN MEDICAL TECH CO LTD
Filing Date
2024-09-14
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Currently, there are no high-performance pure magnesium materials available for intravascular absorbable stents, and pure magnesium materials are prone to softening during deformation, resulting in insufficient physical properties that cannot meet clinical needs.

Method used

Pure magnesium material was processed using a severe plastic deformation method combining equal channel angle pressing and high-pressure torsional extrusion to prepare intravascular bioresorbable pure magnesium stents. Its performance was improved by laser engraving and plasma chemical vapor deposition TiO2 surface treatment.

Benefits of technology

The prepared pure magnesium stent has excellent physical and mechanical properties, good biocompatibility and corrosion resistance, meets the performance indicators of clinical absorbable stents, and is suitable for stent implantation in the fields of cardiovascular and cerebrovascular diseases and hollow organs.

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Abstract

本发明公开了一种血管内生物可吸收纯镁支架的制备方法,包括对纯镁材料的以下加工处理步骤:步骤一:进行等通道角压(ECAP)处理;步骤二:进行高压扭转挤压(HPTE)处理;步骤三:拉拔薄壁管;步骤四:支架设计;步骤五:激光雕刻;步骤六:抛光、清洗和表面处理;步骤七:等离子体化学气相TiO2表面沉积。本技术方案制备方法制备得到的纯镁支架,具有优异的物理机械性能,良好的生物相容性和抗腐蚀性,完全满足临床可吸收支架植入的性能指标要求,具有良好的顺应性和操控性能,易于通过狭窄和扭曲病变,可用于心血管、脑血管、外周血管和空腔脏器等的支架植入需求,将成为临床医生喜欢使用的可吸收纯镁支架,也将为广大患者带来福音。
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