Small-molecule antibacterial active ingredients, methods of making and uses thereof

By processing and purifying the fermentation supernatant of Bacillus subtilis, small molecule antibacterial components with significantly improved stability and activity were obtained, solving the problem of unstable growth environment of Bacillus subtilis in feed additives and achieving a highly efficient antibacterial effect.

CN119192276BActive Publication Date: 2026-06-23CHINA AGRI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHINA AGRI UNIV
Filing Date
2024-09-24
Publication Date
2026-06-23

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Abstract

The application discloses a small-molecule bacteriostatic active ingredient, a preparation method and application thereof. A bacteriostatic active molecule substance metabolized by Bacillus subtilis is separated, which is different from known compounds in structure, and further analysis shows that the obtained small-molecule bacteriostatic active ingredient has a broad-spectrum bacteriostatic ability and has biological characteristics such as high-temperature resistance, acid resistance and protease resistance.
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