一种发酵红参的益生菌及其发酵红参提取物在解酒护肝上的应用

By using *Lactobacillus plantarum* KMHD-1 and *Lactobacillus gasseri* KMBGI 03 to ferment red ginseng extract, the problem of insufficient conversion of rare ginsenosides in existing technologies has been solved, and the content of various rare ginsenosides in red ginseng extract has been significantly increased.

CN119372105BActive Publication Date: 2026-07-17KANGMEIHUA GENE TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
KANGMEIHUA GENE TECH CO LTD
Filing Date
2024-11-07
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

The lack of probiotics in existing technologies that can simultaneously convert multiple rare ginsenosides results in low content of rare ginsenosides in red ginseng products and insufficient bioavailability.

Method used

Lactobacillus plantarum KMHD-1 and Lactobacillus gasseri KMBGI 03 were used as probiotics. The fermentation conditions (static culture at 30~42℃ for 24~96h, water bath at 90~100℃ for 3h) were optimized by fermenting red ginseng extract to increase the content of rare ginsenosides in the red ginseng extract.

Benefits of technology

It significantly increased the content of rare ginsenosides such as Rh1, 20(R)-Rg2, 20(S)-Rg3, 20(R)-Rg3, Rk1 and Rg5 in red ginseng extract, thereby improving bioavailability.

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Abstract

本发明提供了一种发酵红参的益生菌及其发酵红参提取物在解酒护肝上的应用,涉及生物发酵技术领域,所述益生菌包括植物乳植杆菌KMHD‑1和 / 或格氏乳杆菌KMBGI 03,数据显示,经植物乳植杆菌KMHD‑1或格氏乳杆菌KMBGI 03处理后的红参提取液中人参皂苷总量得到显著提高,且经植物乳植杆菌KMHD‑1和格氏乳杆菌KMBGI 03组成的益生菌处理后的红参提取液人参皂苷含量高于植物乳植杆菌KMHD‑1或格氏乳杆菌KMBGI 03单独处理的红参提取液人参皂苷含量。本发明提供的益生菌能够同时提高多种人参皂苷的含量。解决了现有技术中缺少一种能够同时转化多种稀有人参皂苷的益生菌的技术问题。
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