一种木质素基皮克林乳液及其制备方法

By treating lignin with a eutectic solvent to prepare nanoparticles and adjusting the concentration with sodium alginate, the stability and biocompatibility issues of lignin-based Pickering emulsions were resolved, achieving efficient and safe emulsion preparation suitable for the biopharmaceutical, cosmetic, and food industries.

CN119431823BActive Publication Date: 2026-07-17CHINA PHARM UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHINA PHARM UNIV
Filing Date
2024-11-05
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing lignin-based Pickering emulsions have shortcomings in terms of stability and biocompatibility, especially in applications involving anti-photodegradation drugs, and traditional modification methods use non-environmentally friendly reagents.

Method used

Nanoparticles were prepared by treating lignin with a eutectic solvent, and a stable lignin-based Pickering emulsion was prepared by adjusting the concentrations of lignin and sodium alginate. Combined with curcumin loading, a highly efficient oil-in-water emulsion was formed.

Benefits of technology

The prepared emulsion exhibits good storage resistance and dispersion stability, significantly improves the in vitro antioxidant properties and biocompatibility of hydrophobic bioactive components, and the process is safe, green, and non-toxic.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119431823B_ABST
    Figure CN119431823B_ABST
Patent Text Reader

Abstract

本发明公开一种木质素基皮克林乳液及其制备方法,属于生物化学技术领域。本申请写将木质素溶于低共熔溶剂中,稀释,透析,冻干后制得木质素纳米颗粒,再将木质素纳米颗粒与海藻酸钠溶解于水相中,混合水相和油相,经过超高压均质即制得木质素基皮克林乳液。调节溶于低共熔溶剂中的木质素浓度(7.5mg / mL)后制备的纳米粒子的颗粒特性得到明显改善,更适合作为乳液稳定剂;且通过进一步优化水相中的木质素纳米颗粒(1wt%)和海藻酸钠(0.9wt%)的浓度,使得乳液的稳定性得到进一步提升;将疏水生物活性成分(如姜黄素)负载在本申请制备的乳液中,可进一步提高活性成分的抗氧化活性和生物相容性;此乳液在生物医药、化妆品和食品工业等领域均具有广阔的应用前景。
Need to check novelty before this filing date? Find Prior Art