Near-infrared light response microneedle control system and preparation method thereof

Abstract

The invention discloses a near-infrared light response microneedle control system and a preparation method thereof. The microneedle control system is mainly designed based on a light stimulation response LCE-MXene artificial muscle and a PVA / PVP hydrogel microneedle. A functional photo-thermal filler MXene is designed through chemical modification, the functional photo-thermal filler MXene is chemically grafted into an LCE polymer network to design a photoresponse artificial muscle, then the photoresponse artificial muscle is organically integrated with a hydrogel microneedle, and insertion of the microneedle is accurately controlled through driving force generated by LCE-MXene photostimulation contraction actuation. According to the near-infrared light response microneedle control system disclosed by the invention, the depth, the speed and the force of inserting the microneedle into the biological tissue are accurately controlled by controlling the photo-thermal filler content, the near-infrared light intensity and the exposure time of LCE-MXene, and meanwhile, the harsh requirements of different biological tissues on microneedle insertion are met; the method is expected to be widely applied to the fields of interstitial fluid sampling and biosensing detection.

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