Antibacterial central venous catheter and preparation method thereof

Abstract

The invention belongs to the technical field of biomedical material preparation, and provides an antibacterial central venous catheter and a preparation method thereof. According to the method, the pulse frequency in the silver layer deposition process is controlled to be 240-260 kHz, so that the density of the silver nanoparticles is improved, the sputtering rate is increased, the sputtered nanoparticles have high energy, and therefore the adhesive force between the nanoparticles and a base body and the density of the nanoparticles are improved. Meanwhile, the working pressure in the silver layer deposition process is controlled to be 0.24-0.25 Pa, so that the collision frequency of sputtered silver nanoparticles and gas molecules is reduced, the lost energy is small, the diffusivity of deposited particles and a matrix is improved, the compactness and adhesiveness of the coating are improved, and the service life of the coating is prolonged. The defect that in the prior art, the adhesive force between the silver nano coating and the central venous catheter is weak is overcome, and the antibacterial central venous catheter which is high in adhesive force, compactness, stability and purity is prepared.

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