Recombinant I-type humanized collagen and application thereof
CN119462901AActive Publication Date: 2025-02-18ZHUHAI JINBAIKANG BIOLOGICAL TECH CO LTD
Patent Information
- Application Number
- CN202411935546.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-26
- Publication Date
- 2025-02-18
- Estimated Expiration
- 2044-12-26
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Figure CN119462901A_ABST
Abstract
The invention belongs to the technical field of bioengineering, and particularly relates to recombinant I-type humanized collagen and application thereof. A novel I-type humanized collagen sequence is designed, the structural stability and solubility of the I-type humanized collagen can be comprehensively improved, and the product quality of the I-type humanized collagen is improved. According to the invention, the screened new I-type humanized collagen sequence is transferred to the pichia pastoris strain for recombinant expression, and the prepared recombinant I-type humanized collagen has the advantages of strong stability, high expression quantity and good hydrophilicity, and meanwhile, the recombinant I-type humanized collagen also has obvious effects of promoting cell proliferation and cell adhesion.
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Citation Information
Patent Citations
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