Receiving assembly, detection device and blood glucose meter

Abstract

The present application relates to blood glucose detection technical field, disclose a kind of receiving assembly, detection device and blood glucose meter, receiving assembly includes first lens, collimating optical element, light splitting element and photosensitive element, first lens is used to collect and emit the light of target object emission, light includes laser and Raman scattering light, collimating optical element is located in one side of first lens, collimating optical element is used to collimate the light of first lens emission after processing and emit, and filter stray light in Raman scattering light, light splitting element is located in the side of collimating optical element away from first lens, light splitting element is used to receive the light of collimating optical element emission and carry out diffraction light splitting, to make laser and Raman scattering light emit in different direction, photosensitive element is used to receive the Raman scattering light of light splitting element light splitting emission.Using the receiving assembly, detection device and blood glucose meter of the present application embodiment, the interference caused by stray light can be reduced, the signal-to-noise ratio of Raman spectrum is improved, and the sensitivity of blood glucose detection is higher.

Description

Technical Field

[0001] This invention relates to the field of blood glucose detection technology, and in particular to a receiving component, a detection device, and a blood glucose meter. Background Technology

[0002] High blood sugar (glucose in the blood) levels can trigger various acute and long-term complications, such as kidney disease, neurological and circulatory system diseases, cardiovascular disease, blindness, and stroke. Blood sugar testing technologies include invasive, minimally invasive, and non-invasive methods. Invasive and minimally invasive methods can cause pain and discomfort to patients and carry potential risks such as infection.

[0003] Therefore, current blood glucose testing primarily promotes non-invasive methods, using Raman spectroscopy for non-destructive detection of blood glucose in the human body. This involves using a laser to irradiate the patient's skin to generate Raman scattered light, which is then received by a photosensitive element to achieve blood glucose detection.

[0004] However, due to the presence of interfering light such as ambient light and Rayleigh scattering light, the photosensitive element receives stray light while receiving Raman scattered light, resulting in a low signal-to-noise ratio in the Raman spectrum and low sensitivity in blood glucose detection. Summary of the Invention

[0005] This invention discloses a receiving component, a detection device, and a blood glucose meter, which can reduce interference caused by stray light, improve the signal-to-noise ratio of Raman spectroscopy, and achieve high sensitivity in blood glucose detection.

[0006] In a first aspect, embodiments of the present invention disclose a receiving component, including a first lens, a collimating optical element, a beam splitter, and a photosensitive element. The first lens is used to collect light emitted from a target object and to emit the light, which includes laser light and Raman scattered light. The collimating optical element is disposed on one side of the first lens and is used to collimate the light emitted from the first lens before emitting it, and to filter stray light in the Raman scattered light. The beam splitter is disposed on the side of the collimating optical element away from the first lens and is used to receive the light emitted from the collimating optical element and to diffract and split the light so that the laser light and the Raman scattered light are emitted in different directions. The photosensitive element is used to receive the Raman scattered light emitted after being split and emitted by the beam splitter.

[0007] As an optional implementation, in this embodiment of the invention, the collimating optical element includes a light-absorbing part and a plurality of light-transmitting holes. The plurality of light-transmitting holes are spaced apart from the light-absorbing part. The extending direction of the light-transmitting holes is the same as the direction in which the light emitted from the first lens is emitted. The light-absorbing part is used to absorb stray light in the Raman scattered light. The light-transmitting holes are used to collimate the light emitted from the first lens before it is emitted.

[0008] As an optional implementation, in this embodiment of the invention, the optical density of the light-absorbing part is OD, where OD ≥ 4.

[0009] As an optional implementation, in this embodiment of the invention, the diameter of the light-transmitting hole is d, the extension length of the light-transmitting hole is h, and the light collimation angle of the light-transmitting hole is θ, where tanθ = d / h.

[0010] As an optional implementation, in this embodiment of the invention, the light also includes Rayleigh scattered light, and the receiving component further includes a filter disposed between the collimating optical element and the beam splitting element, the filter being used to filter the Rayleigh scattered light.

[0011] As an optional implementation, in this embodiment of the invention, the receiving component further includes a second lens disposed between the beam splitter and the photosensitive element. The second lens is used to receive the Raman scattered light emitted from the beam splitter and focus the Raman scattered light onto the photosensitive element.

[0012] As an optional implementation, in this embodiment of the invention, the second lens includes one of a Fresnel lens, a diffractive lens, and a superlens.

[0013] As an optional implementation, in this embodiment of the invention, the first lens and the collimating optical element are spaced apart, or the first lens abuts against the side of the collimating optical element away from the beam splitter.

[0014] Secondly, embodiments of the present invention disclose a detection device, including a transmitting component and a receiving component, wherein the transmitting component is used to emit a laser towards the target object so that the target object emits the light.

[0015] Thirdly, embodiments of the present invention disclose a blood glucose meter, including the detection device of the second aspect.

[0016] Compared with the prior art, the embodiments of the present invention have at least the following beneficial effects:

[0017] In this embodiment of the invention, a first lens collects light emitted from the target object and directs it to a collimating optical element. The collimating optical element then collimates the light before it is directed to a beam splitter. The beam splitter diffracts and separates the light, causing the laser and Raman scattered light to exit in different directions, thus separating them. The emitted Raman scattered light then reaches a photosensitive element, which uses this Raman scattered light for blood glucose detection, resulting in high sensitivity. Simultaneously, the collimating optical element filters out stray light from the Raman scattered light, reducing interference from stray light and improving the signal-to-noise ratio of the Raman spectrum, thereby further enhancing the sensitivity of blood glucose detection. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the structure of a receiving component disclosed in Embodiment 1 of the present invention;

[0020] Figure 2 This is a schematic diagram of the structure of a collimating optical element disclosed in Embodiment 1 of the present invention;

[0021] Figure 3 This is a schematic diagram of the internal structure of a collimating optical element disclosed in Embodiment 1 of the present invention;

[0022] Figure 4 This is a schematic diagram of the structure of the first lens and collimating optical element in contact, as disclosed in Embodiment 1 of the present invention;

[0023] Figure 5 This is a schematic diagram of the detection device disclosed in Embodiment 2 of the present invention;

[0024] Figure 6 This is a simplified structural diagram of the blood glucose meter disclosed in Embodiment 3 of the present invention.

[0025] Explanation of main figure symbols

[0026] 100. Receiving component; 10. First lens; 11. Collimating optical element; 11a. Light-absorbing part; 11b. Light-transmitting aperture; 12. Beam-splitting element; 13. Photosensitive element; 14. Filter; 15. Second lens; 200. Detection device; 20. Transmitting component; 300. Blood glucose meter; a. Target object. Detailed Implementation

[0027] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0028] In this invention, the terms "upper," "lower," "left," "right," "front," "rear," "top," "bottom," "inner," "outer," "middle," "vertical," "horizontal," "lateral," and "longitudinal" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. These terms are primarily for the purpose of better describing the invention and its embodiments, and are not intended to limit the indicated devices, elements, or components to having a specific orientation, or to be constructed and operated in a specific orientation.

[0029] Furthermore, in addition to indicating direction or positional relationship, some of the aforementioned terms may also have other meanings. For example, the term "above" may also be used in certain situations to indicate a dependency or connection. Those skilled in the art can understand the specific meaning of these terms in this invention based on the specific circumstances.

[0030] Furthermore, the terms "installation," "setup," "equipped with," "connection," and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral structure; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium, or an internal connection between two devices, components, or parts. Those skilled in the art can understand the specific meaning of these terms in this invention based on the specific circumstances.

[0031] Furthermore, the terms "first," "second," etc., are primarily used to distinguish different devices, elements, or components (which may be the same or different in specific type and construction), and are not intended to indicate or imply the relative importance or quantity of the indicated devices, elements, or components. Unless otherwise stated, "a plurality of" means two or more.

[0032] This invention discloses a receiving component, a detection device, and a blood glucose meter, which can reduce interference caused by stray light, improve the signal-to-noise ratio of Raman spectroscopy, and achieve high blood glucose detection sensitivity.

[0033] Example 1

[0034] Please see Figure 1This is a schematic diagram of a receiving component 100 provided in Embodiment 1 of the present invention. The receiving component 100 includes a first lens 10, a collimating optical element 11, a beam splitter 12, and a photosensitive element 13. The first lens 10 is used to collect light emitted from the target object a and to emit light, including laser light and Raman scattered light. The collimating optical element 11 is disposed on one side of the first lens 10. The collimating optical element 11 is used to collimate the light emitted from the first lens 10 before emission and to filter stray light in the Raman scattered light. The beam splitter 12 is disposed on the side of the collimating optical element 11 away from the first lens 10. The beam splitter 12 is used to receive the light emitted from the collimating optical element 11 and to diffract and split the light so that the laser light and Raman scattered light are emitted in different directions. The photosensitive element 13 is used to receive the Raman scattered light emitted after being split by the beam splitter 12.

[0035] In this context, target object 'a' can be the user's skin. A laser is emitted from a laser device onto the user's skin. After reaching the skin's surface, the laser light is absorbed, reflected, and scattered by the skin's constituent substances. Reflection includes the laser light emitted by the device, while scattering includes Rayleigh scattering and Raman scattering. Figure 1 In the image, the optical path of the receiving component 100 is represented by a dashed line.

[0036] For example, the photosensitive element 13 can be an APD (Avalanche Photon Diode) sensor or a SPAD (Single Photon Avalanche Diode) sensor. In this embodiment, the photosensitive element 13 can be an APD as an example.

[0037] In this embodiment, the first lens 10 collects the light emitted from the target object a and directs it to the collimating optical element 11. The collimating optical element 11 then collimates the light before it is directed to the beam splitter 12. The beam splitter 12 diffracts and separates the light, causing the laser and Raman scattered light to exit in different directions, thus separating them. The emitted Raman scattered light is then directed to the photosensitive element 13, where the Raman scattered light is received for blood glucose detection, resulting in high sensitivity. Simultaneously, as the light passes through the collimating optical element 11, it also filters out stray light from the Raman scattered light. This reduces stray light interference when the photosensitive element 13 receives the Raman scattered light, improving the signal-to-noise ratio of the Raman spectrum and further enhancing the sensitivity of blood glucose detection.

[0038] In some embodiments, such as Figure 2 and Figure 3As shown, the collimating optical element 11 includes a light-absorbing part 11a and a plurality of light-transmitting holes 11b. The plurality of light-transmitting holes 11b are spaced apart from the light-absorbing part 11a, and the extending direction of the light-transmitting holes 11b is the same as the direction of the light emitted from the first lens 10. The light-absorbing part 11a is used to absorb stray light in the Raman scattered light, and the light-transmitting holes 11b are used to collimate the light emitted from the first lens 10 before it is emitted. In this way, by using the light-transmitting holes 11b to transmit light, the light is deflected in the light-transmitting holes 11b to achieve collimation of the light, while the light-absorbing part 11a can absorb stray light in the Raman scattered light, thereby reducing the interference of stray light, improving the signal-to-noise ratio of the Raman spectrum, and thus further improving the sensitivity of blood glucose detection.

[0039] The material of the light-absorbing part 11a can be organic black matrix BM or other light-absorbing materials, which can be selected according to the actual situation. This embodiment does not make specific limitations on this.

[0040] Optionally, the optical density of the light-absorbing part 11a is OD, where OD ≥ 4. If the optical density OD of the light-absorbing part 11a is less than 4, the absorption of stray light in the Raman scattered light by the light-absorbing part 11a is poor, and some stray light cannot be absorbed by the light-absorbing part 11a. This causes some stray light to be emitted by the Raman scattered light to the photosensitive element 13, resulting in interference. The signal-to-noise ratio of the Raman spectrum is low, and the sensitivity of blood glucose detection is low. Therefore, the optical density OD of the light-absorbing part 11a can be OD ≥ 4. The light-absorbing part 11a can absorb as much stray light in the Raman scattered light as possible, reducing the interference of stray light on the photosensitive element 13, improving the signal-to-noise ratio of the Raman spectrum, and thus improving the sensitivity of blood glucose detection. Moreover, the optical density OD can be 4, 4.2, 4.4, 4.6, 4.8, 4.5, etc., and this embodiment does not specifically limit it.

[0041] For example, the diameter of the light-transmitting aperture 11b is d, the extension length of the light-transmitting aperture 11b is h, and the light collimation angle of the light-transmitting aperture 11b is θ, where tanθ = d / h. Thus, when light rays reach one opening of the light-transmitting aperture 11b, the light rays are deflected and collimated at the light collimation angle θ. When the light rays exit along the extension direction of the light-transmitting aperture 11b, after traveling a distance d, they are deflected by an amount d along the diameter direction of the light-transmitting aperture 11b, allowing them to exit from the other opening of the light-transmitting aperture 11b without reaching the light-absorbing part 11a around the light-transmitting aperture 11b. This ensures that the light rays entering the light-transmitting aperture 11b from one opening can completely exit from the other opening, resulting in high light utilization.

[0042] Taking into account errors in processing and assembly, tanθ is usually approximately equal to d / h. For example, when θ = 1° and d = 50 μm, h ≈ 2.86 mm.

[0043] In some embodiments, such as Figure 1As shown, the light also includes Rayleigh scattered light, and the receiving component 100 also includes a filter 14, which is disposed between the collimating optical element 11 and the beam splitting element 12. The filter 14 is used to filter Rayleigh scattered light. In this way, filtering Rayleigh scattered light through the filter 14 can avoid interference caused by Rayleigh scattered light, improve the signal-to-noise ratio of the Raman spectrum, and thus improve the sensitivity of blood glucose detection.

[0044] Optionally, the receiving component 100 further includes a second lens 15, which is disposed between the beam-splitting element 12 and the photosensitive element 13. The second lens 15 is used to receive the Raman scattered light emitted from the beam-splitting element 12 and focus the Raman scattered light onto the photosensitive element 13. In this way, by focusing the Raman scattered light onto the photosensitive element 13 through the second lens 15, as much Raman scattered light emitted from the beam-splitting element 12 as possible can reach the photosensitive element 13, thereby improving the utilization rate of the Raman scattered light. The greater amount of Raman scattered light received by the photosensitive element 13 can improve the sensitivity of blood glucose detection.

[0045] For example, the second lens 15 includes one of a Fresnel lens, a diffractive lens, and a superlens. This embodiment provides a variety of second lenses 15 with different structures, which can be selected according to actual needs, and this embodiment does not make a specific limitation.

[0046] Optionally, such as Figure 1 As shown, the first lens 10 and the collimating optical element 11 are spaced apart, or, as... Figure 4 As shown, the first lens 10 abuts against the collimating optical element 11 on the side opposite to the beam splitting element 12. This embodiment provides various arrangements of the first lens 10 and the collimating optical element 11, which can be selected according to actual conditions, and this embodiment does not impose specific limitations on them. For example, if the first lens 10 and the collimating optical element 11 are spaced apart, they are independently manufactured parts, making transportation and assembly more flexible. If the first lens 10 and the collimating optical element 11 abut against each other, they can be independently manufactured parts or integrally formed parts.

[0047] Embodiment 1 of the present invention provides a receiving component 100. A first lens 10 collects light emitted from a target object a, and the light is then directed to a collimating optical element 11. The collimating optical element 11 collimates the light before it is directed to a beam splitter 12. The beam splitter 12 diffracts and separates the light, causing the laser and Raman scattered light to exit in different directions, thus separating the laser and Raman scattered light. The emitted Raman scattered light is directed to a photosensitive element 13, where the Raman scattered light received by the photosensitive element 13 is used for blood glucose detection, resulting in high sensitivity. Simultaneously, as the light passes through the collimating optical element 11, it also filters stray light from the Raman scattered light, reducing interference from stray light when the photosensitive element 13 receives the Raman scattered light, improving the signal-to-noise ratio of the Raman spectrum, and further enhancing the sensitivity of blood glucose detection.

[0048] Example 2

[0049] Please see Figure 5 The diagram below is a schematic structural diagram of a detection device 200 provided in Embodiment 2 of the present invention. The detection device 200 includes a transmitting component 20 and a receiving component 100 in Embodiment 1. The transmitting component 20 is used to emit laser light towards the target object a so that the target object a emits light.

[0050] The emitting component 20 includes a laser. This laser can be a vertical-cavity surface-emitting laser (VCSEL), which can simultaneously emit multiple infrared spots. Alternatively, the emitting component 20 includes a laser and diffractive optical elements. The laser can be an edge-emitting laser, which can emit a single infrared spot. The diffractive optical elements diffuse the single infrared spot, multiplying the number of infrared spots and enabling the emission of multiple infrared spots in a single operation.

[0051] Embodiment 2 of the present invention provides a detection device 200, whose receiving component 100 can reduce interference caused by stray light, improve the signal-to-noise ratio of Raman spectrum, and has high sensitivity for blood glucose detection.

[0052] Example 3

[0053] Please see Figure 6 This is a simplified structural diagram of a blood glucose meter 300 provided in Embodiment 3 of the present invention. The blood glucose meter 300 includes the detection device 200 of Embodiment 2.

[0054] Embodiment 3 of the present invention provides a blood glucose meter 300 with high blood glucose detection sensitivity.

[0055] The foregoing has provided a detailed description of a receiving component, detection device, and blood glucose meter disclosed in the embodiments of the present invention. This article uses specific examples to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only for the purpose of helping to understand the receiving component, detection device, and blood glucose meter of the present invention and its core ideas. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of the present invention. Therefore, the content of this specification should not be construed as a limitation of the present invention.

Claims

1. A receiving component, characterized in that, include: A first lens is used to collect light emitted from a target object and to emit the light, the light including laser light and Raman scattered light; A collimating optical element is disposed on one side of the first lens. The collimating optical element includes a light-absorbing part and a plurality of light-transmitting holes. The plurality of light-transmitting holes are spaced apart from the light-absorbing part. The extending direction of the light-transmitting holes is the same as the direction of the light emitted from the first lens. The optical density of the light-absorbing part is OD, where OD≥4. The light-absorbing part is used to absorb stray light in the Raman scattered light. The light-transmitting holes are used to collimate the light emitted from the first lens before it is emitted. A beam splitter element is disposed on the side of the collimating optical element opposite to the first lens. The beam splitter element receives the light emitted from the collimating optical element and diffracts and splits the light so that the laser and the Raman scattered light are emitted in different directions. A photosensitive element, the photosensitive element being used to receive the Raman scattered light emitted after being split by the beam splitter.

2. The receiving component according to claim 1, characterized in that, The diameter of the light-transmitting hole is d, the extension length of the light-transmitting hole is h, and the light collimation angle of the light-transmitting hole is θ, where tanθ=d / h.

3. The receiving component according to claim 1 or 2, characterized in that, The light also includes Rayleigh scattered light, and the receiving component further includes a filter disposed between the collimating optical element and the beam splitting element, the filter being used to filter the Rayleigh scattered light.

4. The receiving component according to claim 1 or 2, characterized in that, The receiving component further includes a second lens disposed between the beam splitter and the photosensitive element. The second lens is used to receive the Raman scattered light emitted by the beam splitter and focus the Raman scattered light onto the photosensitive element.

5. The receiving component according to claim 4, characterized in that, The second lens includes one of Fresnel lens, diffractive lens, and superlens.

6. The receiving component according to claim 1 or 2, characterized in that, The first lens and the collimating optical element are spaced apart, or the first lens abuts against the side of the collimating optical element away from the beam splitter.

7. A detection device, characterized in that, The device includes a transmitting component and a receiving component as described in any one of claims 1 to 6, wherein the transmitting component is configured to emit a laser towards the target object so that the target object emits the light.

8. A blood glucose meter, characterized in that, Includes the detection device as described in claim 7.

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