Control method, controller, purification device and system for blood purification treatment mode

Abstract

Embodiments of the present application provide a blood purification treatment mode control method, a controller, a purification device and a system, which solve the technical problem of the prior art that the number of integrated treatment modes of the blood purification device is small, the operation is relatively complicated and the convenience is poor. The blood purification treatment mode control method provided by the present application can combine the liquid circuits corresponding to multiple pipeline assemblies by regulating the start or disconnection of multiple pumps, the start or disconnection of multiple functional devices and the conduction or cutoff of multiple connecting pipelines. The liquid circuits corresponding to the multiple pipeline assemblies can correspond to multiple treatment modes, so that more treatment modes are integrated on one blood purification device, and the integration and use convenience of the blood purification device are improved.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a control method, controller, purification equipment, and system for blood purification treatment modes. Background Technology

[0002] Blood purification equipment draws blood out of the body, filters out specific molecules in the blood, and then returns the purified blood back into the body to achieve the effect of treating diseases.

[0003] Continuous blood purification equipment is one type of commonly used blood purification device. It removes excess water, metabolic waste and toxins from the body, corrects electrolyte imbalances, ensures nutritional support, promotes kidney function recovery, and removes various cytokines and inflammatory mediators.

[0004] Blood purification therapy encompasses various treatment modalities, such as slow continuous ultrafiltration, continuous venous-venous hemofiltration, continuous venous-venous hemodialysis, continuous venous-venous hemodiafiltration, dual plasma adsorption therapy, plasma adsorption, plasma exchange, dual plasma exchange, and hemoperfusion. Different blood purification modalities are suitable for different patients. While blood purification equipment can integrate multiple treatment modalities to meet clinical needs, the number of currently integrated modalities is limited, making it difficult to combine more modalities. When multiple patients in an intensive care unit require different treatment modalities, multiple blood purification devices are often needed to meet their needs, significantly increasing costs and making operation relatively cumbersome and inconvenient.

[0005] In addition, for patients who need to receive two different treatment modes, it is difficult for operators to switch between different treatment modes on the same blood purification device, resulting in operational inconvenience. Summary of the Invention

[0006] To address the aforementioned technical problems, this invention is proposed. Embodiments of this invention provide a control method, controller, purification equipment, and system for blood purification treatment modes, solving the technical problems of existing blood purification equipment having a limited number of integrated treatment modes, relatively cumbersome operation, and poor convenience.

[0007] As a first aspect of the present invention, the present invention provides a method for controlling a blood purification treatment mode, applicable to a blood purification system, the blood purification system comprising: a plurality of pumps, at least one functional device, and a plurality of connecting lines connected between the pumps and between the pumps and the functional device;

[0008] The control method includes:

[0009] Obtain the target treatment mode input by the user, wherein the target treatment mode is one or more of a plurality of preset treatment modes;

[0010] Based on the target treatment mode, a target tubing component matching the target treatment mode is determined. The target tubing component includes: a target function device, a target pump, and multiple target connection tubing.

[0011] Acquire the treatment data corresponding to the target treatment mode, and calculate the target opening degree of each target pump based on the treatment data and the performance parameters of the target pump;

[0012] The target pump is activated according to the target opening degree of each target pump to control the conduction of multiple target connection pipelines, forming a liquid circuit corresponding to the target treatment mode.

[0013] In one embodiment of the present invention, obtaining the target treatment mode input by the user includes:

[0014] Obtain the target treatment type input by the user;

[0015] Based on the target treatment type, multiple preset treatment modes corresponding to the target treatment type are determined, so that the multiple preset treatment modes are displayed on the display screen for the user to select the target treatment mode.

[0016] Obtain the target treatment mode selected by the user.

[0017] In one embodiment of the present invention, the blood purification system includes multiple blood treatment components, and the multiple blood treatment components correspond one-to-one with multiple treatment types;

[0018] The process of determining the target tubing components that match the target treatment mode based on the target treatment mode includes:

[0019] Based on the target treatment pattern, determine the target treatment type corresponding to the target treatment pattern from among the multiple treatment types;

[0020] Based on the target treatment type, a target blood treatment component corresponding to the target treatment type is determined from among a plurality of blood treatment components;

[0021] Based on the treatment data of the target treatment mode, the target functional unit, target pump, and target connecting tubing corresponding to the target treatment mode are determined in the target blood treatment component.

[0022] In one embodiment of the present invention, the blood purification system further includes: at least one pipeline selection valve, the pipeline selection valve having at least two valve ports, each of the valve ports being connected to one of the connecting pipelines;

[0023] The step of controlling the start of the target pump according to the target pump's target opening degree to control the connection of multiple target connecting pipelines includes:

[0024] Determine the target pipeline selection valve based on the target connection pipeline;

[0025] The target pipeline selection valve is controlled to open the target connection pipeline, and the target pipeline selection valve is controlled to close the reference connection pipeline, wherein the reference connection pipeline is a connection pipeline other than the target connection pipeline among the multiple connection pipelines connected to the target pipeline selection valve.

[0026] In one embodiment of the present invention, the treatment types include: hemodialysis, plasma exchange, plasma adsorption and plasma perfusion CRRT treatment, plasma therapy and hemoperfusion.

[0027] In one embodiment of the present invention, the preset treatment modes corresponding to the CRRT treatment include: continuous venous hemofiltration pre-dilution (CVVH-pre), continuous venous hemofiltration post-dilution (CVVH-post), continuous venous hemofiltration pre- and post-dilution mixed dilution (CVVH-Mix), continuous venous hemodialysis pre-dilution (CVVHDF-pre), continuous venous hemodialysis post-dilution (CVVHDF-post), continuous venous hemodialysis pre- and post-dilution mixed dilution (CVVHDF-Mix), continuous venous hemodialysis (CVVHD), and slow continuous ultrafiltration (SCUF).

[0028] The preset treatment modes corresponding to the plasma therapy include: plasma exchange (PE), dual filtration plasma exchange (DFPP), paired plasma filtration adsorption (CPFA), plasma adsorption (PA), dual plasma molecular adsorption system (DPMAS), molecular adsorption recirculation system (MARS), plasma separation adsorption system (FPSA), single pass albumin dialysis (SPAD), repeated albumin dialysis (RAD), and plasma filtration dialysis (PDF).

[0029] The preset treatment modes corresponding to the blood perfusion include: blood perfusion (HP).

[0030] As a second aspect of the present invention, the present invention also provides a controller for a blood purification treatment mode, comprising: a data acquisition module, used to acquire a target treatment mode input by a user, wherein the target treatment mode is one or more of a plurality of preset treatment modes;

[0031] The first determining module is used to determine a target tubing component that matches the target treatment mode according to the target treatment mode. The target tubing component includes: a target function device, a target pump, and multiple target connecting tubing.

[0032] The calculation module is used to acquire the treatment data corresponding to the target treatment mode, and calculate the target opening degree of each target pump based on the treatment data and the performance parameters of the target pump.

[0033] Control module: used to control the start of the target pump according to the target opening degree of the target pump, so as to control the conduction of multiple target connection pipelines to form a liquid circuit corresponding to the target treatment mode.

[0034] As a third aspect of the present invention, the present invention also provides a blood purification device, comprising: a plurality of pumps and the controller described above; the blood purification device, together with at least one functional device and a plurality of connecting pipelines connected between the pumps and between the pumps and the functional device, constitute a blood purification system.

[0035] In one embodiment of the present invention, the blood purification device further includes: at least one pipeline selection valve, the pipeline selection valve having at least two valve ports, each of the valve ports being connected to one of the connecting pipelines.

[0036] As a fourth aspect of the present invention, the present invention also provides a blood purification system, the blood purification system comprising: the blood purification device described above and at least one functional device, and a plurality of connecting pipelines connecting the pumps and the pumps and the functional device;

[0037] When the treatment type is CRRT, the corresponding functional device is a dialyzer and / or a filter;

[0038] When the treatment type is plasma therapy, the corresponding functional device is any one or more combinations of plasma separator, plasma component separator, and plasma adsorber.

[0039] When the treatment type is hemoperfusion, the corresponding functional device is a perfusion device.

[0040] This invention provides a control method for a blood purification treatment mode. The blood purification device includes a blood purification system comprising five pumps, multiple functional units, and multiple connecting pipes connecting the pumps and the functional units. By determining the target functional unit, target pump, and target pipe according to the user-input target treatment mode, and calculating the target opening degree of the target pump based on the treatment data of the target treatment mode, the method controls the activation of the target pump and the conduction of the target pipe according to the target opening degree, thereby forming a liquid circuit corresponding to the target treatment mode. Treatment can then be administered to the patient according to the target treatment mode. By adjusting the activation or deactivation of the pumps, the functional units, and the conduction or deactivation of the multiple connecting pipes, liquid circuits corresponding to various pipe components can be combined. Multiple liquid circuits corresponding to multiple pipe components can correspond to multiple treatment modes, thus integrating more treatment modes into a single blood purification device, improving the integration and ease of use of the blood purification device. Attached Figure Description

[0041] The above and other objects, features, and advantages of the present invention will become more apparent from the more detailed description of the embodiments of the invention in conjunction with the accompanying drawings. The drawings are provided to further illustrate the embodiments of the invention and form part of the specification. They are used together with the embodiments of the invention to explain the invention and do not constitute a limitation thereof. In the drawings, the same reference numerals generally represent the same parts or steps.

[0042] Figure 1 The diagram shown is a piping diagram of a blood therapy component corresponding to CRRT treatment, a target treatment type provided in an embodiment of the present invention.

[0043] Figure 2 The diagram shown is a flowchart illustrating a control method for a blood purification treatment mode provided in an exemplary embodiment of the present invention.

[0044] Figure 3a The diagram shown is a piping diagram of the fluid circuit corresponding to the target treatment mode of hemoperfusion (HP) provided by an exemplary embodiment of the present invention.

[0045] Figure 3b The diagram shown is a piping diagram of the fluid circuit corresponding to plasma exchange (PE), a target treatment mode provided by an exemplary embodiment of the present invention.

[0046] Figure 3c The diagram shown is a piping diagram of the liquid circuit corresponding to the target treatment mode of plasma adsorption (PA) provided by an exemplary embodiment of the present invention.

[0047] Figure 4 The diagram shown is a flowchart illustrating a control method for a blood purification treatment mode provided in another exemplary embodiment of the present invention.

[0048] Figure 5 The diagram shown is a flowchart illustrating a control method for a blood purification treatment mode provided in another exemplary embodiment of the present invention.

[0049] Figure 6 The diagram shown is a piping diagram of the fluid circuit corresponding to the target treatment mode of continuous venous dialysis (CVVHD) provided by an exemplary embodiment of the present invention.

[0050] Figure 7 The diagram shown is a piping diagram of the fluid circuit corresponding to the target treatment mode of continuous venous blood filtration pre-dilution (CVVH-pre) provided by an exemplary embodiment of the present invention.

[0051] Figure 8 The diagram shown is a piping diagram of the fluid circuit corresponding to the target treatment mode of continuous venous blood filtration followed by dilution (CVVH-after) provided by an exemplary embodiment of the present invention.

[0052] Figure 9 The diagram shown is a piping diagram of the liquid circuit corresponding to the target treatment mode (Continuous Venous-Ventilary Hemofiltration Pre- and Post-Mix) provided by an exemplary embodiment of the present invention.

[0053] Figure 10 The diagram shown is a piping diagram of the liquid circuit corresponding to the target treatment mode of continuous venous hemodialysis prefiltration dilution (CVVHDF-pre) provided by an exemplary embodiment of the present invention.

[0054] Figure 11 The diagram shown is a piping diagram of the fluid circuit corresponding to the target treatment mode of continuous venous hemodialysis filtration followed by dilution (CVVHDF-after) provided by an exemplary embodiment of the present invention.

[0055] Figure 12 The diagram shown is a piping diagram of the fluid circuit corresponding to the target treatment mode of continuous venous hemodialysis pre- and post-filtration dilution (CVVHDF-Mix) provided by an exemplary embodiment of the present invention.

[0056] Figure 13 The diagram shown is a piping diagram of the liquid circuit corresponding to the target treatment mode of Slow Continuous Ultrafiltration (SCUF) provided by an exemplary embodiment of the present invention.

[0057] Figure 14 The diagram shown is a working block diagram of a controller for a blood purification treatment mode provided by an exemplary embodiment of the present invention.

[0058] Figure 15 The diagram shown is a block diagram of an electronic device provided in an exemplary embodiment of the present invention.

[0059] Figure label:

[0060] 11-First flow pump, 12-Second flow pump, 13-Third flow pump, 14-Fourth flow pump, 2-Blood pump, 51-First line selection valve, 52-Second line selection valve, 61-Dialyzer, 62-Plasma separator, 63-Adsorber, 64-Perfusion device, 7-Bubble monitor, 8-Heater, 81-First replacement line, 82-Second replacement line; 71-First adsorption line, 72-Second adsorption line, 91-Aspiration line, 92-Return line, 93-First CRRT line, 94-Second CRRT line, 95-Third CRRT line, 96-Fourth CRRT line; 97-Fifth CRRT line, 98-Sixth CRRT line, 99-Seventh CRRT line, 41-First pressure sensor, 42-Second pressure sensor, 43-Third pressure sensor, 44-Fourth pressure sensor. Detailed Implementation

[0061] Hereinafter, exemplary embodiments according to the present invention will be described in detail with reference to the accompanying drawings. Obviously, the described embodiments are merely some embodiments of the present invention, and not all embodiments of the present invention. It should be understood that the present invention is not limited to the exemplary embodiments described herein.

[0062] Exemplary blood purification device

[0063] As a first aspect of the present invention, the blood purification device provided by the present invention includes a device body and a display screen. The display screen is used to display content that needs to be displayed during the operation of the blood purification device, such as the treatment types integrated into the blood purification device and multiple preset treatment modes corresponding to each treatment type. Users can see the treatment types and multiple preset treatment modes corresponding to each treatment type on the display screen and select the corresponding target treatment mode.

[0064] The blood purification device provided by this invention also includes multiple flow pumps, a blood pump, and a pipeline selection valve.

[0065] A blood purification device, together with at least one functional unit and multiple connecting lines, constitutes a blood purification system. The connecting lines connect a flow pump, a blood pump, and the functional unit. The flow pump pumps fluid in or out at a preset speed. The blood pump draws blood from the patient and delivers it to the corresponding connecting line. A line selection valve connects multiple connecting lines; for example, a three-way valve with three ports, each connected to a different connecting line, controls the opening and closing of the connecting lines. Furthermore, the flow rate of the fluid in the connecting lines can be controlled by adjusting the valve's opening degree. The functional unit is the device that performs functional processing of the fluid in each preset treatment mode; for example, the functional unit could be a dialyzer 61, a plasma separator 62, an adsorber 63, an perfusion device 64, etc.

[0066] Optionally, the blood purification system includes multiple blood treatment components, each corresponding to a different treatment type. For example, the blood treatment component corresponding to CRRT treatment is a hemodialysis component. Figure 1 The diagram shown is a piping diagram of a blood therapy component corresponding to CRRT treatment according to an embodiment of the present invention. Figure 1As shown, the blood therapy components corresponding to CRRT treatment include a dialyzer 61, a blood collection line 91, a blood return line 92, and a blood pump 2 installed on the blood collection line 91. The blood pump 2 is used to pump blood from the blood collection line 91 into the dialyzer 61, and the blood return line 92 is used to transport the dialyzed blood in the dialyzer 61 to the patient's body; a first CRRT line 93 and a first flow pump 11 installed on the first CRRT line 93, with both ends of the first flow pump 11 connected to the first CRRT line 93 and the reservoir bag, respectively; a second CRRT line 94, a first line selection valve 51, and a second flow pump 12, with both ends of the second flow pump 12 connected to the first CRRT line 93 and the first line selection valve 51, respectively, and both ends of the second CRRT line 94 connected to the first line selection valve 51 and the outlet of the dialyzer 61, respectively; and a third CRRT line 95 and a third flow pump. 13. One end of the third flow pump 13 is connected to the first CRRT line 93 and the second line selection valve 52, and the other end of the third flow pump 13 is connected to one end of the third CRRT line 95. The other end of the third CRRT line 95 is connected to the suction line 91 and the inlet of the dialyzer 61. The sixth CRRT line 98 has two ends connected to the first line selection valve 51 and the third CRRT line 95, respectively. The seventh CRRT line 99 has two ends connected to the second line selection valve 52 and the third CRRT line 95, respectively. The fourth CRRT line 96 and the fourth flow pump 14 have two ends connected to the inlet of the dialyzer 61 and the storage bag, respectively. The fifth CRRT line 97 has two ends connected to the second line selection valve 52 and the outlet of the dialyzer 61, respectively.

[0067] By adjusting the opening or closing of the first flow pump 11, the second flow pump 12, the third flow pump 13, the fourth flow pump 14, the first pipeline selection valve 51, and the second pipeline selection valve 52, the suction line 91, the return line 92, the first CRRT line 93, the second CRRT line 94, the third CRRT line 95, the fourth CRRT line 96, the fifth CRRT line 97, the sixth CRRT line 98, and the seventh CRRT line 99 can be connected or disconnected to accommodate eight treatment modes applicable to hemodialysis. The eight treatment modalities are: continuous venous hemofiltration pre-dilution (CVVH-pre), continuous venous hemofiltration post-dilution (CVVH-post), continuous venous hemofiltration pre- and post-dilution (CVVH-Mix), continuous venous hemodialysis pre-dilution (CVVHDF-pre), continuous venous hemodialysis post-dilution (CVVHDF-post), continuous venous hemodialysis pre- and post-dilution (CVVHDF-Mix), continuous venous hemodialysis (CVVHD), and slow continuous ultrafiltration (SCUF).

[0068] Optionally, the blood purification device may also include a heater 8 and a bubble detector 7, wherein the heater 8 is used to heat the replacement fluid or dialysate, and the bubble detector 7 is used to monitor the presence of bubbles in the return blood line 92.

[0069] Optionally, the blood purification device may also include: pressure sensors disposed on the connecting lines, such as a first pressure sensor 41 disposed on the suction line 91 and before the blood pump 2, a second pressure sensor 42 disposed between the suction line 91 and the blood pump 2, a third pressure sensor 43 disposed on the return line 92, and a fourth pressure sensor 44 disposed on the fourth CRRT line.

[0070] Exemplary control method

[0071] As a second aspect of the present invention, the present invention provides a method for controlling a blood purification treatment mode, applicable to the blood purification system described above. Figure 2 The figure shown is a control method for a blood purification treatment mode provided by an embodiment of the present invention. As shown in Figure 2, the control method for a blood purification treatment mode includes the following steps:

[0072] S1: Obtain the target treatment pattern input by the user.

[0073] Specifically, multiple preset treatment modes integrated into the blood purification device are stored in a preset database. The preset database stores treatment types, multiple preset treatment modes included in each treatment type, and the corresponding liquid connection pipelines for each preset treatment mode.

[0074] Specifically, the method for obtaining the target treatment pattern input by the user, i.e., S1 (obtaining the target treatment pattern input by the user), may include the following steps:

[0075] S11: Obtain the target treatment type input by the user;

[0076] When a user starts the blood purification device, the display screen in the device shows the treatment type. The user selects the target treatment type, and the controller obtains the target treatment type entered by the user.

[0077] Specifically, treatment types include CRRT, plasma therapy, and hemoperfusion.

[0078] (1) The treatment modes corresponding to CRRT include the following 8 treatment modes:

[0079] Continuous venous hemofiltration pre-dilution (CVVH-pre), continuous venous hemofiltration post-dilution (CVVH-post), continuous venous hemofiltration pre- and post-dilution (CVVH-Mix), continuous venous hemodialysis pre-dilution (CVVHDF-pre), continuous venous hemodialysis post-dilution (CVVHDF-post), continuous venous hemodialysis pre- and post-dilution (CVVHDF-Mix), continuous venous hemodialysis (CVVHD), and slow continuous ultrafiltration (SCUF).

[0080] (2) The treatment modalities corresponding to plasma therapy include the following 10 modalities:

[0081] Plasma exchange (PE), dual filtration plasma exchange (DFPP), paired plasma filtration adsorption (CPFA), plasma adsorption (PA), dual plasma molecular adsorption system (DPMAS), molecular adsorption recirculation system (MARS), plasma separation adsorption system (FPSA), single pass albumin dialysis (SPAD), repeated albumin dialysis (RAD), and plasma filtration dialysis (PDF).

[0082] (3) The treatment modalities corresponding to plasma perfusion include the following one:

[0083] Plasma perfusion (HP).

[0084] S12: Determine multiple preset treatment modes corresponding to the target treatment type based on the target treatment type, so that the multiple preset treatment modes are displayed on the display screen;

[0085] Once the controller receives the target treatment type input by the user, it will search the preset database for a preset treatment mode that matches the target treatment type. For example, if the user selects CRRT treatment as the target treatment type, then the corresponding preset treatment modes are the eight treatment modes mentioned above.

[0086] Once the target treatment type and its corresponding preset treatment modes are determined, the controller sends these preset treatment modes to the display screen. The display screen then shows the corresponding preset treatment modes, such as the eight treatment modes corresponding to CRRT treatment. When displaying treatment modes, the Chinese name of the treatment mode can be shown, or the English abbreviation corresponding to the treatment mode can be restricted. For example, the eight treatment modes displayed on the display screen are: CVVH-before, CVVH-after, CVVH-Mix, CVVHDF-before, CVVHDF-after, CVVHD, CVVHDF-Mix, CUF, SPAD, and RAD.

[0087] S13: Obtain the target treatment mode selected by the user.

[0088] When the display screen shows multiple preset treatment modes corresponding to the target treatment type, the user can select the corresponding target treatment mode. After the user clicks on the target treatment mode on the display screen, the controller can obtain the target treatment mode input by the user. For example, if the user clicks to select CVVHDF-Mix on the display screen, then the corresponding controller will obtain the target treatment mode input by the user as: Continuous Venous-Venous Hemodialysis Pre- and Post-Filtration Mixing Dilution (CVVHDF-Mix).

[0089] S2: Determine the target tubing components that match the target treatment mode based on the target treatment mode. The target tubing components include multiple target pumps, target function devices, and multiple target connection tubing.

[0090] Specifically, the preset database stores the target tubing components corresponding to each treatment mode. The target tubing components include the target pump, target function, and target connection tubing required by the target treatment mode. Therefore, once the target treatment mode input by the user is determined, the corresponding target tubing components can be matched in the preset database according to the target treatment mode.

[0091] For example, such as Figure 3a As shown, when the user inputs the target treatment mode as "plasma perfusion mode", the corresponding target functional device is perfusion device 64, and the target pump is blood pump 2. The target connecting lines are: suction line 91 and return line 92.

[0092] For example Figure 3bAs shown, when the user inputs the target treatment mode as "Plasma Exchange (PE)," the corresponding target functional unit is the plasma separator 62. The target pumps are: blood pump 2, fourth flow pump 14, and first flow pump 11. The target connecting lines are: suction line 91, return line 92, first replacement line 81, and second replacement line 82. The second replacement line 82 is used to pump plasma from the reservoir bag into the return line 92. The first replacement line 81 and the fourth flow pump 14 are used to transport the waste liquid generated by the plasma separator 62 to the waste liquid bag.

[0093] For example Figure 3c As shown, when the user inputs the target treatment mode as "Plasma Adsorption (PA)," the corresponding target functional units are the plasma separator 62 and the adsorber 63. The target pumps are the blood pump 2 and the first flow pump 11. The target connecting lines are the suction line 91, the return line 92, the first adsorption line 71, and the second adsorption line 72. Specifically, the first adsorption line 71 connects the outlet of the plasma separator 62 to one end of the adsorber 63, and the second adsorption line 72 connects the return line 92 to the other end of the adsorber 63.

[0094] For example, such as Figure 8 As shown, when the user inputs the target treatment mode as: Continuous Venous-Venous Hemofiltration Post-Dilution (CVVH-Post), the treatment data for CVVH-Post are as follows: treatment time over 24 hours, blood pump flow rate 50-200 ml / min, renal dose 20-25 ml / (kg*h), ultrafiltration flow rate: renal dose * patient weight, replacement fluid flow rate 1500-2000 ml / h, and no dialysate. The target functional component in the target tubing assembly corresponding to the target treatment mode is dialyzer 61, the target pumps are: blood pump 2, fourth flow pump 14, and first flow pump 11; the target connection tubing is: aspiration tubing 91, return tubing 92, first CRRT tubing 93 connecting the reservoir bag and the first flow pump 11, second CRRT tubing 94 connecting the first CRRT tubing 93 and the return tubing 92, and fourth CRRT tubing 96 connecting the inlet of dialyzer 61 and the waste bag.

[0095] Once the target piping assembly is determined, the corresponding piping diagram can be displayed on the display screen, as shown in Figure 3. This guides the user to assemble the target piping assembly according to the diagram. In other words, the user can connect the target piping to the target pump and the target functional unit based on the corresponding piping diagram displayed on the display screen to form the liquid circuit of the target piping assembly.

[0096] S3: Obtain the treatment data corresponding to the target treatment mode, and calculate the target opening degree of the target pump based on the treatment data and the performance parameters of the target pump;

[0097] Once the user has completed the pipe connections according to the target piping component, the controller can obtain the treatment data corresponding to the target treatment mode. Specifically, the treatment data for the target treatment mode can be input by the user or retrieved from a preset database.

[0098] Once the treatment data corresponding to the target treatment mode is determined, the target opening degree of the target pump can be calculated based on the treatment data and the performance parameters of the target pump.

[0099] Specifically, the performance parameters of the target pump are: the relationship between the pump opening degree and the pump speed.

[0100] S4: Control the start of the target pump according to the target pump opening degree, and control the connection of multiple target connection pipelines to form a liquid circuit with the target liquid bag corresponding to the target treatment mode.

[0101] Once the target opening degree of each target pump is determined, the target pump can be started according to the target pump opening degree, and multiple target connecting pipes can be connected to form a liquid circuit corresponding to the target treatment mode with the target liquid bag, so that the blood drawn from the patient's body can be returned to the patient's body after treatment.

[0102] This invention provides a control method for a blood purification treatment mode. The blood purification device includes a blood purification system comprising five pumps, multiple functional units, and multiple connecting pipes connecting the pumps and functional units. By determining the target functional unit, target pump, and target pipe according to the user-input target treatment mode, and calculating the target pump opening degree based on the treatment data of the target treatment mode, the method controls the activation of the target pump and the conduction of the target pipe according to the target opening degree, thereby forming a fluid circuit corresponding to the target treatment mode. Treatment can then be administered to the patient according to the target treatment mode. By adjusting the activation or deactivation of the pumps, the functional units, and the conduction or deactivation of the multiple connecting pipes, fluid circuits corresponding to various pipe components can be combined. Multiple fluid circuits corresponding to multiple pipe components can correspond to multiple treatment modes, thus integrating more treatment modes into a single blood purification device, improving the integration and ease of use of the blood purification device.

[0103] In one embodiment of the present invention, the blood purification system includes multiple blood treatment components, each corresponding to a different treatment type, for example... Figure 1 The blood therapy component shown is for CRRT (Continuous Renal Replacement Therapy). Therefore, as... Figure 4As shown, S2 (determining the target tubing assembly matching the target treatment pattern based on the target treatment pattern) may include the following steps:

[0104] S21: Based on the target treatment pattern, determine the target treatment type corresponding to the target treatment pattern from among multiple treatment types;

[0105] The treatment type corresponding to each treatment mode can be stored in a preset database. When the user inputs the target treatment mode, the controller can match it in the preset database to determine the target treatment type corresponding to the target treatment mode.

[0106] For example, if the user inputs the target treatment mode as: continuous venous hemofiltration followed by dilution (CVVH-), then the corresponding target treatment type is CRRT treatment.

[0107] S22: Determine the target blood therapy component corresponding to the target treatment type from among multiple blood therapy components based on the target treatment type;

[0108] Once the target treatment type of the target treatment mode is determined, the corresponding target blood therapy component can be selected from multiple blood therapy components. For example, if the target treatment mode is CRRT treatment, the target blood therapy component corresponding to CRRT treatment can be determined, such as... Figure 1 The blood therapy component shown.

[0109] Once the target blood therapy component is identified, it is displayed on the control panel. Users can manually connect the corresponding pumps, functional units, and connecting pipes according to the piping diagram of the target blood therapy component displayed on the control panel to form the corresponding piping for the target blood therapy component.

[0110] S23: Based on the treatment data of the target treatment mode, determine the target functional unit, target pump, and target connecting pipeline corresponding to the target treatment mode in the target blood treatment component.

[0111] Selecting the corresponding target function and target pump within the target blood therapy component allows for faster selection of the target pump.

[0112] Specifically, the method for determining the target functional unit and target pump in the target blood therapy component based on the target treatment mode can be as follows:

[0113] The target functional unit is determined based on the treatment data corresponding to the target treatment mode, and then the target pump is determined based on the target functional unit.

[0114] For example, if the user inputs a target treatment mode of Slow Continuous Ultrafiltration (SCUF), the corresponding target blood therapy component would be the blood therapy component for CRRT treatment (such as...). Figure 1 As shown), the treatment data for Slow Continuous Ultrafiltration (SCUF) are as follows: treatment time is at least 24 hours, blood pump flow rate is 50-100 ml / min, renal dose is 20-25 ml / (kg*h), ultrafiltration flow rate is 2-5 ml / min, the total ultrafiltration volume per session does not exceed 4 L, and there is no replacement fluid or dialysate. The treatment data for Slow Continuous Ultrafiltration (SCUF) do not require replacement fluid or dialysate; only dialysis is needed. Therefore, it is possible to... Figure 1 In the target blood treatment component shown, the target treatment device is identified as a dialyzer, and the target pump is a pump that can pump out the waste liquid after dialysis. Therefore, the fourth flow pump can be identified as the target pump.

[0115] S24: Based on the target functional unit and the target pump, determine the target connection tubing in the target blood therapy component.

[0116] Once the target pump and target function are selected, the target connection pipeline can be determined based on the target pump and target function.

[0117] For example, when the user inputs the target treatment mode as Slow Continuous Ultrafiltration (SCUF), then in Figure 1 In the blood therapy assembly shown, the dialyzer is directly identified as the target functional unit, and the fourth flow pump 14 is the target pump. In the target blood therapy assembly, the fourth CRRT tubing 96 is directly identified as the target connection tubing.

[0118] When a patient changes their target treatment modality, and the treatment type of the new target treatment modality remains the same, there is no need for manual reassembly of the pump, connecting tubing, and functional devices. The system can directly select the corresponding pump, functional device, and connecting tubing based on the new target treatment modality, and directly control the activation of the corresponding pump and functional device, as well as the continuity of the corresponding connecting tubing. Simultaneously, it controls the shutdown of pumps unrelated to the new target treatment modality and cuts off unrelated connecting tubing.

[0119] In one embodiment of the present invention, in addition to the pump, functional unit, and connecting pipelines described above, the blood purification system also includes a pipeline selection valve. The pipeline selection valve has at least two valve ports, each connected to a connecting pipeline. That is, two or more connecting pipelines can be connected through the pipeline selection valve. By controlling the opening or closing of the pipeline selection valve, the connection between two connecting pipelines can be opened or closed. For example, the blood purification system includes blood treatment components (such as...) Figure 1(As shown) includes two pipeline selection valves: a first pipeline selection valve 51 and a second pipeline selection valve 52. The three ports of the first pipeline selection valve 51 are connected to the first CRRT pipeline 93, the second CRRT pipeline 94, and the sixth CRRT pipeline 98, respectively. The three ports of the second pipeline selection valve 52 are connected to the third CRRT pipeline 95, the seventh CRRT pipeline 99, and the fifth CRRT pipeline 97, respectively. By controlling the opening or closing of the three ports of the first pipeline selection valve 51, the connections between the first CRRT pipeline 93 and the second CRRT pipeline 94, the second CRRT pipeline 94 and the sixth CRRT pipeline 98, and the first CRRT pipeline 93 and the sixth CRRT pipeline 98 can be connected or disconnected. By controlling the opening or closing of the three valve ports of the second pipeline selection valve 52, the connection or disconnection of the third CRRT pipeline 95 and the seventh CRRT pipeline 99, the seventh CRRT pipeline 99 and the fifth CRRT pipeline 97, and the third CRRT pipeline 95 and the fifth CRRT pipeline 97 can be achieved.

[0120] By setting up pipeline selection valves, the entire blood purification system can be configured with fewer pumps to form more fluid circuits, thus adapting to more treatment modes.

[0121] When a blood purification system includes a tubing selection valve, controlling the target tubing to open it is necessary to control the selection valve. Figure 5 As shown, S4 (controlling the target pump to start based on the target opening degree of each target pump to control the connection of multiple target pipelines) specifically includes the following steps:

[0122] S41: Determine the target pipeline selection valve based on the target connection pipeline;

[0123] Once the target connecting tube is determined, if a tubing selection valve is connected to the target connecting tube, then the target tubing selection valve corresponding to the target connecting tube must be determined. For example, when the user inputs the target treatment mode as Continuous Venous-Venous Hemodialysis (CVVHD), the blood therapy component (such as...) corresponding to the treatment type of CRRT treatment for CVVHD must be determined. Figure 1 Once the suction line 91, return line 92, fourth CRRT line 96, and second CRRT line 94 are identified as the target connection lines (as shown), the first line selection valve 51 on the second CRRT line 94 can be identified as the target line selection valve.

[0124] S42: Control the target pipeline selection valve to open the target connection pipeline, and control the target pipeline selection valve to close the reference connection pipeline. The reference connection pipeline is the connection pipeline other than the target connection pipeline among the multiple connection pipelines connected to the target pipeline selection valve.

[0125] Once the target pipeline selector valve is determined, it can be controlled to open the target connection pipeline and simultaneously close other connection pipelines.

[0126] For example, if the user inputs the target treatment mode as continuous venous hemodialysis (CVVHD), the target pump is determined to be dialyzer 61; the target connecting lines are: suction line 91, return line 92, fourth CRRT line 96, second CRRT line 94, and first CRRT line 93; and the target line selection valve is first line selection valve 51.

[0127] This allows the first pipeline selection valve 51 to shut off the second CRRT pipeline 94 and the sixth CRRT pipeline 97, while simultaneously opening the second CRRT pipeline 94 and the first CRRT pipeline 93; at the same time, the second pipeline selection valve 52 remains inactive.

[0128] S43: Control the start of multiple target pumps according to the target opening degree of each target pump.

[0129] The user-input target treatment mode is continuous venous hemodialysis (CVVHD). Blood pump 2, the fourth flow pump 14, and the first flow pump 11 are identified as the target pumps. Therefore, by controlling the conduction of blood pump 2, the fourth flow pump 14, and the first flow pump 11, the tubing diagram of the target tubing assembly for continuous venous hemodialysis (CVVHD) is as follows. Figure 6 As shown.

[0130] To better understand the present invention, specific embodiments are used as examples to describe the invention in detail below. The treatment type corresponding to the treatment modes in Embodiments 1-9 is CRRT treatment, and the blood treatment component corresponding to CRRT treatment is a CRRT treatment component, such as... Figure 1 As shown.

[0131] Example 1: The target treatment mode is: continuous venous-venous hemofiltration predilution (CVVH-pre).

[0132] Continuous venous hemofiltration pre-dilution (CVVH-pre): Before hemodialysis, blood is diluted with replacement fluid. The corresponding treatment data are as follows: treatment time: more than 24 hours, blood pump flow rate: 50-200 ml / min, renal dose: 20-25 ml / (kg*h), replacement fluid flow rate: 1500-2000 ml / l.

[0133] The control methods for blood purification treatment modes include the following steps:

[0134] S101: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0135] S102: Based on the treatment data of continuous venous filtration predilution (CVVH-pre), dialyzer 61 is identified as the target functional device, blood pump 2, third flow pump 13, fourth flow pump 14 and first flow pump 11 are identified as target pumps, and third CRRT tubing 95, first CRRT tubing 93, fourth CRRT tubing 96, aspiration tubing 91 and return tubing 92 are identified as target connection lines.

[0136] S103: Determine the opening of blood pump 2, the opening of third flow pump 13, the opening of fourth flow pump 14, and the opening of first flow pump 11 based on treatment data from continuous venous hemofiltration predilution (CVVH-pre).

[0137] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0138] The opening of the first flow pump 11 and the third flow pump 13 is calculated based on the replacement fluid flow rate (1500-2000 ml / l) in the treatment data.

[0139] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0140] S104: Control the blood pump to start and open the blood collection line; control the first flow pump 11 to open the first CRRT line; control the fourth flow pump 14 to open so that the fourth CRRT line is connected to the drain port of the dialyzer 61; control the third flow pump 13 to connect the third CRRT line 95 to the first CRRT line 93.

[0141] S105: Control all devices in the CRRT treatment assembly except the target pump to stop operating, thereby disconnecting all connecting lines in the CRRT treatment assembly except the target connecting line. For example, control the second flow pump 12, the first line selection valve 51, and the second line selection valve 52 to stop operating, disconnecting the first CRRT line 93 and the second CRRT line 94, and disconnecting the first CRRT line 93 and the seventh CRRT line 99. After S101 to S105, the continuous venous blood filtration pre-dilution (CVVH-pre) fluid circuit is as follows: Figure 7 As shown.

[0142] Example 2: Target treatment mode: Continuous venous-venous hemofiltration followed by dilution (CVVH-after)

[0143] Continuous venous filtration followed by dilution (CVVH-after): After hemodialysis, blood is diluted with replacement fluid. The corresponding treatment data are as follows: treatment time: more than 24 hours, blood pump flow rate: 50-200 ml / min, renal dose: 20-25 ml / (kg*h), replacement fluid flow rate: 1500-2000 ml / l.

[0144] The control methods for blood purification treatment modes include the following steps:

[0145] S201: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0146] S202: Based on the treatment data of continuous venous hemofiltration after dilution (CVVH-), dialyzer 61 is identified as the target functional device, blood pump 2, fourth flow pump 14, second flow pump 12 and first flow pump 11 are identified as target pumps, and second CRRT tubing 94, fourth CRRT tubing 96, aspiration tubing 91 and return tubing 92 are identified as target connection tubing.

[0147] S203: Determine the opening of blood pump 2, the opening of fourth flow pump 14, and the opening of first flow pump 11 based on treatment data from continuous venous hemofiltration after dilution (CVVH-).

[0148] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0149] The opening degree of the first flow pump 11 and the second flow pump 12 is calculated based on the replacement fluid flow rate (1500-2000 ml / l), the performance parameters of the first flow pump 11, and the performance parameters of the second flow pump 12 in the treatment data.

[0150] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0151] S204: Control the blood pump 2 to start and open the aspiration line 91; control the first flow pump 11 to start and open the first CRRT line 93 and the replacement fluid reservoir bag; control the opening of two valve ports of the first line selection valve and the start of the second flow pump 12 to open the connection between the first CRRT line 93 and the second CRRT line 94 and close the connection between the first CRRT line 93 and the sixth CRRT line 98; control the start of the fourth flow pump 14 to connect the fourth CRRT line 96 and the drain port of the dialyzer 61; S105: Control all other devices in the CRRT treatment assembly except the target pump to stop working, so as to close all other connection lines in the CRRT treatment assembly except the target connection line. For example, the third flow pump 13 and the second pipeline selector valve 52 are both stopped, cutting off the first CRRT pipeline 93 and the third CRRT pipeline 95, the first CRRT pipeline 93 and the fifth CRRT pipeline 97, the first CRRT pipeline 93 and the seventh CRRT pipeline 99, and the fifth CRRT pipeline 97 and the seventh CRRT pipeline 99.

[0152] After S201 to S205, the fluid circuit for continuous venous-venous hemofiltration post-dilution (CVVH-) is as follows: Figure 8 As shown.

[0153] Example 3: The target treatment mode is: continuous venous-venous hemofiltration pre- and post-mix dilution (CVVH-Mix).

[0154] Continuous venous-venofiltration pre- and post-mix dilution (CVVH-Mix): Blood is diluted with replacement fluid before and after hemodialysis. The corresponding treatment data are as follows: treatment time: more than 24 hours, blood pump flow rate: 50-200 ml / min, renal dose: 20-25 ml / (kg*h), pre-replacement fluid flow rate: 1500-2000 ml / l, post-replacement fluid flow rate: 1500-2000 ml / l.

[0155] The control methods for blood purification treatment modes include the following steps:

[0156] S301: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0157] S302: Based on the treatment data of continuous venous-venous hemofiltration pre- and post-mix dilution (CVVH-Mix), dialyzer 61 is identified as the target functional device, blood pump 2, fourth flow pump 14, second flow pump 12 and first flow pump 11 are identified as target pumps, second CRRT tubing 94, first CRRT tubing 93, second CRRT tubing 94, third CRRT tubing 95, fourth CRRT tubing 96, aspiration tubing 91 and return tubing 92 are identified as target connection tubing, and first tubing selection valve 51 and second tubing selection valve 52 are identified as target tubing selection valves;

[0158] S303: Treatment data from continuous venous-venous hemofiltration pre- and post-mix dilution (CVVH-Mix) determine the opening of blood pump 2, first flow pump 11, second flow pump 12, and fourth flow pump 14.

[0159] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0160] The opening degree of the first flow pump 11 is calculated based on the sum of the pre-displacement fluid flow rate (1500-2000 ml / l) and the post-displacement fluid flow rate (1500-2000 ml / l) in the treatment data and the performance parameters of the first flow pump. The opening degree of the second flow pump 12 is calculated based on the post-displacement fluid flow rate (1500-2000 ml / l) and the performance parameters of the second flow pump 12.

[0161] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0162] S304: Control the blood pump 2 to start and open the aspiration line 91; control the first flow pump 11 to start and open the replacement fluid reservoir bag and the first CRRT line 93; control the second flow pump 12 to start and open two of the valve ports of the first line selection valve 51 to open the first CRRT line 93 and the second CRRT line 94, and close the first CRRT line 93 and the sixth CRRT line 98;

[0163] The fourth flow pump 14 is started to connect the fourth CRRT line 96 to the drain port of the dialyzer 61; two of the valve ports of the second line selection valve 52 are opened to connect the first CRRT line 93 and the seventh CRRT line 99 and to disconnect the seventh CRRT line 99 and the fifth CRRT line 97.

[0164] S305: Controls all devices in the CRRT treatment assembly except the target pump to stop operating, thereby disconnecting all connecting lines in the CRRT treatment assembly except the target connecting line. For example, controlling the third flow pump 13 to stop operating, thereby disconnecting the first CRRT line 93 and the third CRRT line 95.

[0165] After S301 to S305, the fluid circuit for continuous venous-venous hemofiltration pre- and post-mix dilution (CVVH-Mix) is as follows: Figure 9 As shown.

[0166] Example 4: The target treatment mode is: continuous venous hemodialysis prefiltration dilution (CVVHDF-pre).

[0167] Continuous venous hemodialysis prefiltration dilution (CVVHDF-pre): The corresponding treatment data are as follows: treatment time: more than 24 hours, blood pump flow rate: 50-200 ml / min, renal dose: 20-25 ml / (kg*h), replacement fluid flow rate: 1000-1500 ml / l, dialysate flow rate: 1000-1500 ml / l.

[0168] The control methods for blood purification treatment modes include the following steps:

[0169] S401: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0170] S402: Based on the treatment data of continuous venous hemodialysis prefiltration dilution (CVVHDF-pre), dialyzer 61 is identified as the target functional device, blood pump 2, fourth flow pump 14, third flow pump 13 and first flow pump 11 are identified as target pumps, first CRRT line 93, fifth CRRT line 97, third CRRT line 95, fourth CRRT line 96, aspiration line 91 and return line 92 are identified as target connection lines, and second line selection valve 52 is identified as the target line selection valve;

[0171] S403: Determine the opening of blood pump 2, first flow pump 11, third flow pump 13, and fourth flow pump 14 based on treatment data from continuous venous hemodialysis prefiltration dilution (CVVHDF-pre).

[0172] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0173] The opening degree of the first flow pump 11 is calculated based on the replacement fluid flow rate (1000-1500 ml / l) in the treatment data and the performance parameters of the first flow pump. The opening degree of the third flow pump 13 is calculated based on the dialysate flow rate (1000-1500 ml / l) and the performance parameters of the third flow pump 13.

[0174] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0175] S404: Control blood pump 2 to start and open blood collection line 91; control first flow pump 11 and third flow pump 13 to start and control two valve ports of second line selection valve 52 to open first CRRT line 93 and third CRRT line 95, open first CRRT line 93 and fifth CRRT line 97, and close first CRRT line 93 and seventh CRRT line 99;

[0176] The fourth flow pump 14 is started to connect the fourth CRRT line 96 to the drain port of the dialyzer 61.

[0177] S405: Control all devices in the CRRT treatment assembly except the target pump to stop working, thereby disconnecting all connecting lines in the CRRT treatment assembly except the target connecting line. For example, control the second flow pump 12 to stop working and control the first line selection valve 51 to stop working (i.e., all three valve ports are closed), thereby disconnecting the first CRRT line 93 from the second CRRT line 94 and the first CRRT line 93 from the sixth CRRT line 98.

[0178] After S401 to S405, the fluid circuit for continuous venous-venous hemodialysis pre-filtration dilution (CVVHDF-pre) is as follows: Figure 10 As shown.

[0179] Example 5: Target treatment mode: Continuous venous hemodialysis post-filtration dilution (CVVHDF-after)

[0180] Continuous venous hemodialysis after filtration (CVVHDF-after): The corresponding treatment data are as follows: treatment time: more than 24 hours, blood pump flow rate: 50-200 ml / min, renal dose: 20-25 ml / (kg*h), replacement fluid flow rate: 1000-1500 ml / l, dialysate flow rate: 1000-1500 ml / l.

[0181] The control methods for blood purification treatment modes include the following steps:

[0182] S501: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0183] S502: Based on the treatment data of continuous venous hemodialysis after filtration dilution (CVVHDF-), dialyzer 61 is identified as the target functional device, blood pump 2, fourth flow pump 14, second flow pump 12 and first flow pump 11 are identified as target pumps, first CRRT line 93, fifth CRRT line 97, second CRRT line 94, fourth CRRT line 96, aspiration line 91 and return line 92 are identified as target connection lines, and first line selection valve 51 and second line selection valve 52 are identified as target line selection valves;

[0184] S503: Treatment data for continuous venous hemodialysis after filtration dilution (CVVHDF-) determine the opening of blood pump 2, first flow pump 11, second flow pump 12, and fourth flow pump 14.

[0185] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0186] The opening degree of the first flow pump 11 is calculated based on the sum of the replacement fluid flow rate (1000-1500 ml / l) and the dialysate flow rate (1000-1500 ml / l) in the treatment data, as well as the performance parameters of the first flow pump. The opening degree of the second flow pump 12 is calculated based on the replacement fluid flow rate (1000-1500 ml / l) and the performance parameters of the second flow pump 12.

[0187] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0188] S504: Control blood pump 2 to start and open blood collection line 91; control the start of first flow pump 11 and second flow pump 12 and control the opening of two valve ports of first line selection valve 51 to open first CRRT line 93 and second CRRT line 94, and close first CRRT line 93 and sixth CRRT line 98. Control two valve ports of second line selection valve 52 to open first CRRT line 93 and fifth CRRT line 97 and close first CRRT line 93 and seventh CRRT line 99.

[0189] The fourth flow pump 14 is started to connect the fourth CRRT line 96 to the drain port of the dialyzer 61.

[0190] S505: Controls all devices in the CRRT treatment assembly except the target pump to stop operating, thereby disconnecting all connecting lines in the CRRT treatment assembly except the target connection line. For example, controlling the third flow pump 13 to shut down, i.e., not starting the third flow pump 13, to disconnect the first CRRT line 93 and the third CRRT line 95.

[0191] After S501 to S505, the fluid circuit for continuous venous hemodialysis post-filtration dilution (CVVHDF-) is as follows: Figure 11 As shown.

[0192] Example 6: Target treatment mode: Continuous venous hemodialysis (CVVHD)

[0193] Continuous venous hemodialysis (CVVHD): The corresponding treatment data are as follows: treatment time: more than 24 hours, blood pump flow rate: 50-200 ml / min, renal dose: 20-25 ml / (kg*h), dialysate flow rate: 1000-1500 ml / l.

[0194] The control methods for blood purification treatment modes include the following steps:

[0195] S601: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0196] S602: Based on the treatment data of continuous venous hemodialysis (CVVHD), dialyzer 61 is identified as the target functional device, blood pump 2, fourth flow pump 14 and first flow pump 11 are identified as target pumps, first CRRT line 93, fifth CRRT line 97, fourth CRRT line 96, suction line 91 and return line 92 are identified as target connection lines, and second line selection valve 52 is identified as the target line selection valve.

[0197] S603: Treatment data for continuous venous hemodialysis (CVVHD) determine the opening of blood pump 2, the opening of the first flow pump 11, and the opening of the fourth flow pump 14;

[0198] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0199] The opening degree of the first flow pump 11 is calculated based on the dialysis fluid flow rate (1000-1500 ml / l) in the treatment data, the performance parameters of the first flow pump 11, and the second flow pump 12.

[0200] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0201] S604: Control the blood pump 2 to start and open the blood collection line 91; control the first flow pump 11 to start and open the dialysate storage bag and the first CRRT line 93; control the two valve ports of the second line selection valve 52 to open the first CRRT line 93 and the fifth CRRT line 97, and close the first CRRT line 93 and the seventh CRRT line 99.

[0202] The fourth flow pump 14 is started to connect the fourth CRRT line 96 to the drain port of the dialyzer 61;

[0203] S605: Controls all devices in the CRRT treatment assembly except the target pump to stop operating, thereby disconnecting all connecting lines in the CRRT treatment assembly except the target connection line. For example, controls the second flow pump 12 and the third flow pump 13 to stop operating, thereby disconnecting the first CRRT line 93 from the second CRRT line 94, and the first CRRT line 93 from the fifth CRRT line 95; controls all three valve ports of the first line selection valve 51 to close, thereby disconnecting the first CRRT line 93 from the sixth CRRT line 98, and the sixth CRRT line 98 from the second CRRT line 94.

[0204] After S601 to S605, the fluid circuit for continuous venous hemodialysis (CVVHD) is as follows: Figure 6 As shown.

[0205] Example 7: Target treatment mode: Continuous venous-to-venous hemodialysis pre- and post-filtration mix dilution (CVVHDF-Mix)

[0206] Continuous venous-to-venous hemodialysis pre- and post-filtration dilution (CVVHDF-Mix): After hemodialysis, the blood is diluted with replacement fluid. The corresponding treatment data are as follows: treatment time: more than 24 hours, blood pump flow rate: 50-200 ml / min, renal dose: 20-25 ml / (kg*h), replacement fluid flow rate: 1000-1500 ml / l, dialysate flow rate: 1000-1500 ml / l.

[0207] The control methods for blood purification treatment modes include the following steps:

[0208] S701: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0209] S702: Treatment data for continuous venous hemodialysis pre- and post-filtration dilution (CVVHDF-Mix) determined dialyzer 61 as the target functional device, blood pump 2, third flow pump 13, fourth flow pump 14, second flow pump 12 and first flow pump 11 as target pumps, first CRRT tubing 93, third CRRT tubing 95, fifth CRRT tubing 97, second CRRT tubing 94, fourth CRRT tubing 96, aspiration tubing 91 and return tubing 92 as target connection tubing, and first tubing selection valve 51 and second tubing selection valve 52 as target tubing selection valves;

[0210] S703: Determine the opening of blood pump 2, first flow pump 11, second flow pump 12, third flow pump 13, and fourth flow pump 14 based on treatment data from continuous venous hemodialysis pre- and post-filtration dilution (CVVHDF-Mix).

[0211] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0212] The opening degree of the first flow pump 11 is calculated based on the sum of the replacement fluid flow rate (1000-1500 ml / l) and the dialysate flow rate (1000-1500 ml / l) in the treatment data, as well as the performance parameters of the first flow pump 11. The opening degree of the second flow pump 12 is calculated based on the replacement fluid flow rate (1000-1500 ml / l) and the performance parameters of the second flow pump 12. The opening degree of the third flow pump 13 is calculated based on the dialysate flow rate (1000-1500 ml / l) and the performance parameters of the third flow pump 13.

[0213] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0214] S704: Control the blood pump 2 to start and open the aspiration tube 91; control the first flow pump 11 and the third flow pump 13 to start and control two of the valve ports of the second pipeline selection valve 52 to open the first CRRT pipeline 93 and the third CRRT pipeline 95, open the first CRRT pipeline 93 and the fifth CRRT pipeline 97, and close the fifth CRRT pipeline 97 and the seventh CRRT pipeline 99; control the second flow pump 12 to start and control two of the valve ports of the first pipeline selection valve 51 to open the first CRRT pipeline 93 and the fourth CRRT pipeline 94, and close the first CRRT pipeline 93 and the sixth CRRT pipeline 98;

[0215] The fourth flow pump 14 is started to connect the fourth CRRT line 96 to the drain port of the dialyzer 61;

[0216] S705: Controls all devices in the CRRT treatment assembly except the target pump to stop operating, thereby disconnecting all connecting lines in the CRRT treatment assembly except for the target connection line.

[0217] After S701 to S705, the fluid circuit for continuous venous-venous hemodialysis pre- and post-filtration mixing (CVVHDF-Mix) is as follows: Figure 12 As shown.

[0218] Example 8: Target treatment mode: Slow Continuous Ultrafiltration (SCUF)

[0219] Slow continuous ultrafiltration (SCUF): The corresponding treatment data are as follows: treatment time is at least 24 hours, blood pump flow rate is 50-100 ml / min, kidney volume is 20-25 ml / (kg*h), ultrafiltration flow rate is 2-5 ml / min, the total amount of ultrafiltration per session does not exceed 4L, and there is no replacement fluid or dialysate.

[0220] The control methods for blood purification treatment modes include the following steps:

[0221] S801: Determine the treatment type of the target treatment mode as CRRT treatment, and determine the corresponding target treatment type as CRRT treatment among multiple treatment types based on CRRT treatment, and determine the corresponding target blood treatment component as CRRT treatment component among multiple blood treatment components based on CRRT treatment;

[0222] S802: Based on the treatment data of slow continuous ultrafiltration (SCUF), dialyzer 61 is identified as the target functional device, blood pump 2 and fourth flow pump 14 are identified as target pumps, and fourth CRRT tubing 96, aspiration tubing 91 and return tubing 92 are identified as target connection tubing.

[0223] S803: Determine the opening of blood pump 2 and the opening of the fourth flow pump 14 based on the treatment data of slow continuous ultrafiltration (SCUF).

[0224] The opening degree of blood pump 2 is calculated based on the blood pump flow rate (50-200 ml / min) in the treatment data and the performance parameters of blood pump 2.

[0225] The opening degree of the fourth flow pump 14 is the opening degree when the waste liquid in the dialyzer 61 is pumped out.

[0226] S804: Control the blood pump 2 to start and open the blood collection line 91; control the fourth flow pump 14 to start and connect the fourth CRRT line 96 to the drain port of the dialyzer 61.

[0227] S805: Controls all devices in the CRRT treatment assembly except the target pump to stop working, thereby cutting off all connecting lines in the CRRT treatment assembly except the target connecting line. For example, controls the first flow pump 11, the second flow pump 12, and the third flow pump 13 to stop working, and controls all three valve ports of the first line selection valve 51 and the second line selection valve 52 to close.

[0228] After S801 to S805, the liquid loop for slow continuous ultrafiltration (SCUF) is as follows: Figure 13 As shown.

[0229] Exemplary controller

[0230] As a third aspect of the invention, the invention also provides a controller for a blood purification treatment mode, such as... Figure 14 As shown, the controller 100 includes:

[0231] The data acquisition module 101 is used to acquire the target treatment mode input by the user, wherein the target treatment mode is one or more of a variety of preset treatment modes;

[0232] The first determining module 102 is used to determine the target tubing components that match the target treatment mode according to the target treatment mode. The target tubing components include: a target function device, a target pump, and multiple target connection tubing.

[0233] The calculation module 103 is used to acquire the treatment data corresponding to the target treatment mode, and calculate the target opening degree of each target pump based on the treatment data and the performance parameters of multiple target pumps.

[0234] Control module 104: Used to control the start of the target pump according to the target opening degree of the target pump, so as to control the conduction of multiple target connection pipelines and form a liquid circuit corresponding to the target treatment mode.

[0235] Exemplary continuous blood purification system

[0236] As a fourth aspect of the present invention, the present invention also provides a blood purification system, including the blood purification device described above, at least one functional device, a reservoir bag storing a target liquid, and a plurality of connecting pipes connecting the pump and the functional device.

[0237] The control method of the treatment mode described above selects the corresponding functional device, the target reservoir bag containing the target liquid, and the target device in the blood purification equipment (such as the target pump, the target pipeline selection valve, etc.) according to the target treatment mode, and selects the corresponding target connection pipeline according to the target device to form the liquid pipeline corresponding to the target treatment mode.

[0238] Specifically, a blood purification system may include multiple blood therapy components corresponding to different treatment types. For example, when the treatment type is CRRT, the corresponding blood therapy component is the CRRT therapy component, such as... Figure 1 As shown.

[0239] When the treatment type is CRRT, the corresponding functional device is a dialyzer and / or a filter;

[0240] When the treatment type is plasma therapy, the corresponding functional device is any one or more combinations of plasma separator, plasma component separator, and plasma adsorber.

[0241] When the treatment type is hemoperfusion, the corresponding functional device is the perfusion device.

[0242] Exemplary electronic devices

[0243] Figure 15 The figure shows a structural block diagram of an electronic device according to an embodiment of the present invention.

[0244] like Figure 15 As shown, the electronic device 200 includes one or more processors 201 and memory 202.

[0245] The processor 201 may be a central processing unit (CPU) or other form of processing unit with data processing and / or instruction execution capabilities, and may control other components in the electronic device 200 to perform desired functions.

[0246] The memory 202 may include one or more computer program products, which may include various forms of computer-readable storage media, such as volatile memory and / or non-volatile memory. The volatile memory may include, for example, random access memory (RAM) and / or cache memory. The non-volatile memory may include, for example, read-only memory (ROM), hard disk, flash memory, etc. One or more computer program instructions may be stored on the computer-readable storage medium, and the processor 201 may execute the program instructions to implement a control method for a blood purification treatment mode according to the various embodiments of the present invention described above, and / or other desired functions. Various contents such as input signals, signal components, and noise components may also be stored in the computer-readable storage medium.

[0247] In one example, the electronic device 200 may also include an input device 203 and an output device 204, which are interconnected via a bus system and / or other forms of connection mechanism (not shown).

[0248] When the electronic device 200 is a standalone device, the input device 203 can be a communication network connector for receiving the collected input signals from the first device and the second device.

[0249] In addition, the input device 203 may also include, for example, a keyboard, a mouse, etc.

[0250] The output device 204 can output various information to the outside, including determined distance information, direction information, etc. The output device 204 may include, for example, a display, a speaker, a printer, and a communication network and its connected remote output devices, etc.

[0251] Of course, for the sake of simplicity, Figure 15 Only some of the components of the electronic device 200 relevant to the present invention are shown, omitting components such as buses, input / output interfaces, etc. In addition, the electronic device 200 may include any other suitable components depending on the specific application.

[0252] The computer program product can be written in any combination of one or more programming languages ​​to perform the operations of the embodiments of the present invention. The programming languages ​​include object-oriented programming languages ​​such as Java and C++, as well as conventional procedural programming languages ​​such as C or similar languages. The program code can be executed entirely on the user's computing device, partially on the user's computing device, as a standalone software package, partially on the user's computing device and partially on a remote computing device, or entirely on a remote computing device or server.

[0253] The computer-readable storage medium may be any combination of one or more readable media. A readable medium may be a readable signal medium or a readable storage medium. A readable storage medium may, for example, include, but is not limited to, electrical, magnetic, optical, electromagnetic, infrared, or semiconductor systems, apparatuses, or devices, or any combination thereof. More specific examples of readable storage media (a non-exhaustive list) include: electrical connections having one or more wires, portable disks, hard disks, random access memory (RAM), read-only memory (ROM), erasable programmable read-only memory (EPROM or flash memory), optical fibers, portable compact disk read-only memory (CD-ROM), optical storage devices, magnetic storage devices, or any suitable combination thereof.

[0254] The above description has been given for purposes of illustration and description. Furthermore, this description is not intended to limit the embodiments of the invention to the forms disclosed herein. Although numerous exemplary aspects and embodiments have been discussed above, those skilled in the art will recognize certain variations, modifications, alterations, additions, and sub-combinations therein.

Claims

1. A controller for a blood purification treatment mode, characterized in that, The controller is used to control a blood purification system, which includes: multiple pumps, at least one functional unit, and multiple connecting lines connecting the pumps and the functional unit. The blood purification system includes multiple blood treatment components, each corresponding to a different treatment type. The blood purification system also includes at least one line selection valve having at least two ports, each port connected to one of the connecting lines. The controller includes: The data acquisition module is used to acquire the target treatment mode input by the user, wherein the target treatment mode is one or more of a variety of preset treatment modes; The first determining module is configured to: determine, based on the target treatment mode, a target treatment type corresponding to the target treatment mode from among a plurality of treatment types, wherein the target treatment type includes any one of CRRT treatment, plasma therapy, and hemoperfusion; determine, based on the target treatment type, a target blood therapy component corresponding to the target treatment type from among a plurality of blood therapy components; and determine, based on the treatment data of the target treatment mode, a target functional device, a target pump, and a target connecting pipeline corresponding to the target treatment mode from among the target blood therapy components. The calculation module is used to acquire the treatment data corresponding to the target treatment mode, and calculate the target opening degree of each target pump based on the treatment data and the performance parameters of the target pump. The control module is used to determine the target pipeline selection valve according to the target connection pipeline; control the target pipeline selection valve to open the target connection pipeline to form a liquid circuit corresponding to the target treatment mode; and control the target pipeline selection valve to close the reference connection pipeline, wherein the reference connection pipeline is a connection pipeline other than the target connection pipeline among the multiple connection pipelines connected to the target pipeline selection valve.

2. The controller according to claim 1, characterized in that, The data acquisition module is used to acquire the target treatment pattern input by the user, including: The data acquisition module is used to acquire the target treatment type input by the user; determine multiple preset treatment modes corresponding to the target treatment type according to the target treatment type, so that the multiple preset treatment modes are displayed on the display operation screen for the user to select the target treatment mode; and acquire the target treatment mode selected by the user.

3. The controller according to claim 1, characterized in that, The preset treatment modes corresponding to CRRT treatment include: continuous venous hemofiltration pre-dilution (CVVH-pre), continuous venous hemofiltration post-dilution (CVVH-post), continuous venous hemofiltration pre- and post-dilution mixed dilution (CVVH-Mix), continuous venous hemodialysis pre-dilution (CVVHDF-pre), continuous venous hemodialysis post-dilution (CVVHDF-post), continuous venous hemodialysis pre- and post-dilution mixed dilution (CVVHDF-Mix), continuous venous hemodialysis (CVVHD), and slow continuous ultrafiltration (SCUF). The preset treatment modes corresponding to the plasma therapy include: plasma exchange (PE), dual filtration plasma exchange (DFPP), paired plasma filtration adsorption (CPFA), plasma adsorption (PA), dual plasma molecular adsorption system (DPMAS), molecular adsorption recirculation system (MARS), plasma separation adsorption system (FPSA), single pass albumin dialysis (SPAD), repeated albumin dialysis (RAD), and plasma filtration dialysis (PDF). The preset treatment modes corresponding to the blood perfusion include: blood perfusion (HP).

4. A blood purification device, characterized in that, include: A plurality of pumps and a controller as described in any one of claims 1-3; The blood purification device, together with at least one functional unit and multiple connecting pipes connecting the pumps and the pumps and the functional unit, constitute a blood purification system.

5. The blood purification device according to claim 4, characterized in that, The blood purification device further includes: at least one pipeline selection valve having at least two valve ports, each of which is connected to one of the connecting pipelines.

6. A blood purification system, characterized in that, The blood purification system includes: the blood purification device as described in claim 4 or 5, at least one functional device, and a plurality of connecting pipes connecting the pumps and the pumps and the functional device; When the treatment type is CRRT, the corresponding functional device is a dialyzer and / or a filter; When the treatment type is plasma therapy, the corresponding functional device is any one or more combinations of plasma separator, plasma component separator, and plasma adsorber. When the treatment type is hemoperfusion, the corresponding functional device is a perfusion device.

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