一种治疗放射性肠炎的中药透皮贴剂的制备方法
By preparing a transdermal patch containing traditional Chinese medicine ingredients and probiotics, the problem of traditional oral administration of Chinese medicine has been solved, achieving a highly effective and low-side-effect treatment for radiation enteritis, improving intestinal flora and inflammation, and enhancing the treatment effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- CANCER CENT OF GUANGZHOU MEDICAL UNIV
- Filing Date
- 2024-12-17
- Publication Date
- 2026-07-17
AI Technical Summary
Existing treatments for radiation enteritis have significant side effects, limited efficacy, and lack a unified strategy. Traditional Chinese medicine patches can serve as an effective alternative, but traditional Chinese medicine is difficult to ingest. Therefore, transdermal patches are being developed to address this issue.
The transdermal patch is made by combining extracts of Chinese medicinal herbs such as white peony root, scutellaria baicalensis, angelica sinensis, cinnamon, areca nut, prepared licorice root, rhubarb, coptis chinensis, costus root, red clover, and polygonum multiflorum vine with fermentation of Lactobacillus reuteri and Streptococcus thermophilus, and adding penetration enhancers and solubilizers to treat through skin penetration.
Probiotic fermentation enhances the activity of traditional Chinese medicine components, improves the balance of intestinal flora, enhances transdermal drug absorption, provides multi-target treatment for radiation enteritis, reduces intestinal inflammation, and improves treatment efficacy.
Smart Images
Figure CN119564646B_ABST