Hybridoma cell strain and antibody for detecting rituximab and biosimilar drugs thereof and application of hybridoma cell strain and antibody

CN119570743AActive Publication Date: 2025-03-07BEIJING DIAGREAT BIOTECH CO LTD
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Patent Information

Application Number
CN202510134590.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-02-07
Publication Date
2025-03-07
Estimated Expiration
2045-02-07

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Abstract

The invention relates to a hybridoma cell strain for detecting rituximab and biosimilar drugs thereof, an antibody and application thereof, and belongs to the technical field of biological detection. The hybridoma cell strain provided by the invention is a hybridoma cell strain combination and comprises a hybridoma cell strain RTX-9C02 and a hybridoma cell strain RTX-5B12 which can secrete monoclonal antibodies which are specifically combined with rituximab; the generated monoclonal antibodies RTX-9C02 and RTX-5B12 can be combined for detecting the blood concentration of the rituximab and the biologically similar drugs thereof, and the effect of stably, accurately and highly specifically detecting the rituximab and the biologically similar drugs thereof is achieved.
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Citation Information

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