Etomidate analogue mass spectrum pyrolysis analysis method based on EI-MS mode

Abstract

The invention discloses an etomidate analogue mass spectrum pyrolysis analysis method based on an EI-MS mode. The etomidate analogue mass spectrum pyrolysis analysis method comprises the following steps: (1) obtaining a characteristic fragment ion sequence of a suspicious object in the EI-MS mode; wherein the molecular structural formula of the suspicious etomidate analogue is # imgabs0 # (2) according to the characteristic fragment ion sequence, judging whether the characteristic fragment ion sequence meets the condition of the etomidate analogue, if so, turning to step (3), and if not, turning to step (4); if not, considering that the suspicious object is not the etomidate analogue, and ending the analysis; (3) solving the equation (b) according to the characteristic fragment ion sequence, and judging the structure of R1 in the suspicious object; and (4) solving the equation (c) according to the characteristic fragment ion sequence, and judging the structure of R2 in the suspicious object. And (5) restoring the structure of the suspicious object, and ending the analysis. The method has the advantages of being accurate and rapid in detection, low in cost and wide in universality.

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