一种利用结晶盐模板制备定向多孔水凝胶的方法

The method of preparing directional porous hydrogels by crystallization salt template has solved the problems of high energy consumption and size limitation in the existing technology, and realized the preparation of highly biocompatible porous hydrogels with controllable pore structure at room temperature, which is suitable for tissue engineering.

CN119684662BActive Publication Date: 2026-07-17ZHEJIANG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG UNIV
Filing Date
2024-12-03
Publication Date
2026-07-17

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Abstract

本发明提供一种利用盐结晶模板制备定向多孔水凝胶的方法，通过将盐与水凝胶单体混合，冷却成为含过饱和的盐水凝胶溶液，再将晶核模板置于该溶液中指导盐晶体的成核和生长，最后经历水凝胶固化和清洗的方式，制备得到各向异性、高度有序、孔结构尺寸可控且具有高生物相容性水凝胶。该制备方法具有设备简单、成本低、简便易操作的特点，且水凝胶可选择制备材料种类宽泛，在组织工程领域中有广泛应用前景。
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