Peptide compounds and methods of treating diseases thereof

By using 5 or 7 amino acids composed of specific amino acid sequences to isolate the peptides and activate the Akt signaling system, the problem of difficulty in reducing cellular and immune stress responses in the prior art is solved, and effective reduction of inflammatory and autoimmune diseases is achieved.

CN119708141APending Publication Date: 2025-03-28IMMUNE PHARMACEUTICALS LTD
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Patent Information

Application Number
CN202411888869.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2020-01-15
Filing Date
2021-01-14
Publication Date
2025-03-28

AI Technical Summary

Technical Problem

The prior art is difficult to effectively weaken the cellular and immune stress responses in normal tissues, resulting in the difficulty in reducing the severity of inflammatory and autoimmune diseases.

Method used

An isolated peptide consisting of 5 or 7 amino acids, consisting of a specific amino acid sequence, is provided to reduce dexamethasone-induced spleen and/or thymus weight loss, protecting cells by activating the Akt signaling system.

Benefits of technology

This peptide can significantly reduce dexamethasone-induced spleen and thymus weight loss and minimize dexamethasone-induced spleen and thymus cell count, providing a specific, safe and effective way to reduce the severity of inflammatory and autoimmune diseases.

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Abstract

The present application provides peptide compounds and methods of treating diseases thereof. Isolated peptides are capable of reducing the amount of dexamethasone-induced weight loss of the spleen and / or thymus in a mouse. Use of the plurality of isolated peptides for the treatment of inflammatory or degenerative diseases.
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