一种嵌合硒点益生菌及其制备方法和应用
By growing selenium dots in situ on the surface of probiotics, chimeric selenium dot probiotics were prepared, which solved the problem of poor adhesion of nano-selenium in the intestine, enhanced the antioxidant activity and intestinal adhesion ability of probiotics, and achieved better therapeutic effects on inflammation-related diseases.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- INSTITUTE OF PROCESS ENGINEERING CHINESE ACADEMY OF SCIENCES
- Filing Date
- 2024-09-25
- Publication Date
- 2026-07-17
AI Technical Summary
Currently, when probiotics are used to treat inflammation-related diseases, nano-selenium has poor adhesion in the intestines and is easily metabolized and excreted, resulting in limited therapeutic effects. Furthermore, it cannot effectively eliminate reactive oxygen free radicals, which can worsen the inflammatory response.
By growing selenium dots in situ on the surface of probiotics, chimeric selenium dot probiotics are prepared. Using probiotics as the main structure, selenium precursors are adsorbed and reduced by a reducing agent to form selenium dots grown on the surface, thereby enhancing antioxidant activity and intestinal adhesion ability.
It enhances the antioxidant activity and intestinal adhesion ability of probiotics, achieving better therapeutic effects on inflammation-related diseases and strengthening the homeostasis and immune regulation functions of the gut microbiota.
Smart Images
Figure CN119709463B_ABST