Preparation for pet oral health and preparation method thereof

By using peptide-enzyme complexes and crosslinking agents in pet oral preparations to modify the enzyme surface, combined with traditional Chinese medicine active substances and vegetable oils, rapid and long-term antibacterial and cleansing effects are achieved, solving the problems of poor effect and low safety of existing preparations, and significantly improving pet oral and gastrointestinal health.

CN119746047APending Publication Date: 2025-04-04WATSON VICTOR BIOENGINEERING (LUOHE) CO LTD
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Patent Information

Application Number
CN202510039199.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-10
Publication Date
2025-04-04

AI Technical Summary

Technical Problem

Existing pet oral preparations have poor results, long onset time, insufficient specificity and low safety, making it difficult to effectively prevent and treat pet oral and gastrointestinal diseases.

Method used

By combining papain, pectinase, antimicrobial peptide, EDC and NHS, peptide-enzyme complex is formed, crosslinking agents are used to modify the enzyme surface, combined with Chinese medicine active substances and vegetable oil, deep bactericidal and removal of oral odor, and gastrointestinal digestive function is improved by covering probiotics with trehalose.

Benefits of technology

It significantly inhibits oral and gastrointestinal bacteria, prevents oral diseases such as periodontitis and dental caries, improves pet oral and gastrointestinal health, and has the characteristics of rapid, long-term and safeness.

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Abstract

The invention belongs to the technical field of veterinary pharmaceutical preparations, and specifically relates to a preparation for pet oral health and a preparation method thereof, wherein the preparation comprises the following raw materials: a peptide-enzyme complex, a Chinese medicine composition, a probiotic composition, a cross-linking agent, an enteric material, a surfactant and a vegetable oil, wherein the preparation is covalently linked to form a peptide-enzyme complex by an amidation reaction with nisin, papain and pectinase, and has high-efficiency antibacterial, targeting and sustained-release effects while ensuring enzyme activity, and the probiotics are embedded with a cross-linking agent and an enteric material to effectively maintain activity and reduce loss in the stomach, and then can be prepared into different dosage forms of sprays, emulsions, granules, dry suspensions, gels, orodisintegrating tablets and chewable tablets by adding pharmaceutical excipients, and has good drugability, strong action, a wide range of applications, and is non-irritating to the oral mucosa and the gastrointestinal tract.
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