Tabletting device with controllable screening structure for pharmaceutical tablet production
Patent Information
- Application Number
- CN202410753868.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-12
- Publication Date
- 2026-09-25
- Estimated Expiration
- 2044-06-12
AI Technical Summary
[0004]上述压片机在将药物粉末压成药片并弹至收集盘的过程中,由于药片在压制成型前为粉末状态,其大部分药片存在表面粘覆大量药粉的情况,且一部分药片在成型过程还存在个别碎裂现象,导致药片不成型,进而直接收集后会影响后续包装处理和用药剂量精准度,在药片压制成型且后期包装的时候还需要刻意去对药片附着粉末再次分拣筛分,需要再配合人工操作筛网或筛分机对药物进行筛分处理,制备过程耗时较长,十分繁琐
本发明中,振筛架在依靠微型振动电机的偏心轮结构实现持续振筛时,其两侧连接的限位环则通过内壁内胶圈与限位桩套设,保持振筛范围符合限定,避免大幅度晃动影响整体设备运作稳定,而振筛架内框所连接的筛滤线缆则通过两端调控滑块连接于内框滑槽,并通过相互交叉形成筛网,此筛网可通过筛滤线缆两端连接的调控滑块配合双端电机连接滑轮实现调节,多组调控滑块之间可通过控制保持等距状态下的滑动扩张和内缩之间间距,从而形成不同的筛滤网规格,从而可应对不同尺寸规格的圆型药片,进而保持可控筛分过程,保持高适配性,减少制备流程繁琐度;
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Figure CN119748957B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of pharmaceutical tablet manufacturing technology, specifically to a tablet compression molding apparatus with a controllable sieving structure for manufacturing pharmaceutical tablets. Background Technology
[0002] Tablets are solid dosage forms that are compressed into tablets or irregularly shaped tablets after a drug and excipients are uniformly mixed. Tablets are mainly oral tablets, but there are also lozenges, sublingual tablets, oral patches, chewable tablets, dispersible tablets, effervescent tablets, vaginal tablets, immediate-release or sustained-release or controlled-release tablets, and enteric-coated tablets, etc. In the current technology, in order to facilitate the preservation and swallowing of the drug, powdered drugs are compressed into tablets, and most of the existing technologies use rotary tablet presses.
[0003] In the manufacture of pharmaceutical tablets using a rotary tablet press, the drug is loaded into a device called a feed tray. The feed speed is controlled according to given process parameters. A scraper pushes excess drug back into the feed tray, ensuring uniform distribution. After the drug is evenly dispersed in the feed tray, the die rotates, descends, and compresses the drug. The die can be preheated electronically if required. As the die descends, the machine applies sufficient pressure to deform and fix the powdered or granular drug within the die's space, forming tablets of a fixed size and shape. The die then rises and opens, ejecting the compressed tablets into a collection tray at the other end.
[0004] In the process of pressing drug powder into tablets and ejecting them to the collection tray, the tablets are in a powder state before being pressed. Most of the tablets have a large amount of powder adhering to their surface, and some tablets are broken during the forming process, resulting in tablets that are not formed. If collected directly, this will affect the subsequent packaging process and the accuracy of the dosage. When the tablets are pressed and packaged, it is necessary to deliberately sort and sieve the powder adhering to the tablets again. This requires manual operation of sieves or sieving machines to sieve the drugs. The preparation process is time-consuming and very cumbersome.
[0005] To address the aforementioned problems, we propose a tableting apparatus with a controllable sieving structure for pharmaceutical tablet manufacturing. Summary of the Invention
[0006] The purpose of this invention is to provide a tableting apparatus with a controllable sieving structure for manufacturing pharmaceutical tablets, so as to solve the problems mentioned in the background art.
[0007] To achieve the above objectives, the present invention provides the following technical solution: a tableting device for manufacturing pharmaceutical tablets with a controllable sieving structure, comprising a tablet press, wherein a sieving chamber is provided inside one side of the tablet press, and a conveyor chain is provided at the bottom end of the sieving chamber, the sieving chamber includes a fan, and a vibrating screen frame is provided at the bottom of the fan, baffles are connected to the top surfaces of both sides of the vibrating screen frame, and limit rings are distributed at both ends of the baffles, an inner rubber ring is fitted to the inner wall of the limit ring, and a limit post is fitted on the inner diameter of the inner rubber ring with a reserved gap, a micro vibration motor is connected around the bottom of the vibrating screen frame, and screening cables are arranged crosswise on the inner frame of the vibrating screen frame, an adjusting slider is connected to both ends of the screening cables, and a double-ended motor is provided inside the adjusting slider, pulleys are connected to both ends of the double-ended motor, and grooves are equally spaced on both sides of the adjusting slider along the inner frame of the vibrating screen frame, a discharge rack is provided at one end of the vibrating screen frame, and a waste bin is provided at the bottom of the vibrating screen frame.
[0008] Furthermore, the filter cable and the control sliders connected to both ends are arranged in a mesh pattern along the sliding groove structure of the inner frame of the vibrating screen, and the filter cable is made of nylon fiber braiding.
[0009] Furthermore, the control slider is slidably engaged with the inner frame of the vibrating screen frame via pulleys, and the vibrating screen frame is connected and fixed to the two side cavities inside the screening chamber via miniature vibration motors distributed at both ends.
[0010] Furthermore, the two ends of the vibrating screen frame are fitted onto the outer wall of the limiting pile by limiting rings, and the limiting pile is connected and fixed to the two cavities inside the screening chamber.
[0011] Furthermore, the tablet press includes an outer frame, and a collection box is fitted inside the outer frame. A tablet pressing assembly is provided on one side of the top of the outer frame, and a material cylinder is connected to the top of the tablet pressing assembly. Glass covers are distributed around the tablet pressing assembly.
[0012] Furthermore, one side of the top of the outer frame is connected and fixed to the glass cover and the tablet pressing assembly, and the top of the tablet pressing assembly is connected to the material cylinder.
[0013] Furthermore, the conveyor chain includes a chain frame, and the inner wall of the chain frame is provided with a conveying groove. A conveyor belt is provided in the middle of the conveying groove, and a diverter plate is connected to the outer walls of the conveyor belt. Servo motors are connected to both ends of the chain frame.
[0014] Furthermore, the conveying trough is inclined along the inner walls of both sides of the chain frame, and the outer walls of both sides of the chain frame are fixedly connected to the inner walls of both sides of the screening chamber.
[0015] Furthermore, the two ends of the conveyor belt are connected to the chain frame via servo motors to form a transmission structure, and the diverter plates are arranged at equal intervals along the outer wall of the conveyor belt.
[0016] Compared with the prior art, the beneficial effects of the present invention are: In this invention, when the vibrating sieve frame achieves continuous vibrating sieve by relying on the eccentric wheel structure of the micro vibration motor, the limiting rings connected on both sides are fitted with limiting stakes through the inner rubber rings on the inner wall to keep the vibrating sieve range within the limit and avoid large-scale shaking that affects the overall stability of the equipment operation. The sieve cable connected to the inner frame of the vibrating sieve frame is connected to the inner frame slide groove through the two ends of the adjustable slider and forms a sieve by intersecting each other. This sieve can be adjusted by the adjustable sliders connected to both ends of the sieve cable in conjunction with the pulleys connected to the double-end motor. The distance between the sliding expansion and contraction of multiple sets of adjustable sliders can be controlled to maintain an equidistant state, thereby forming different sieve specifications. This can handle round tablets of different sizes and specifications, thereby maintaining a controllable sieve process, maintaining high adaptability, and reducing the complexity of the preparation process. In this invention, in order to maintain the stability of the tableting process of the tablet press during the manufacturing of pharmaceutical tablets, an external protective structure is adopted to provide stability to the tableting process. When the tablet press is manufacturing pharmaceutical tablets, the powder material can be put into the cylinder and conveyed to the rotary tableting assembly connected to the bottom for stable and efficient tableting. When the tableting assembly is making tablets, the entire structure is within the glass cover, which provides protection for the entire assembly, maintains the anti-interference process of tableting, and reduces the influence of external impurities during the tableting process. In this invention, in order to maintain the efficient screening, powder removal, and impurity removal process of the overall device during the discharge process and to reduce the complexity of the preparation process, this tableting assembly can form a vibration process through the vibrating screen frame and the connected micro vibration motor during the tablet discharge operation. It can work with the internally connected cross-arranged screening cables to continuously vibrate, screen, and remove powder and impurities from the conveyed tablets. During the process, the top fan blows air downwards, causing the powder and broken tablets shaken out by the vibrating screen to fall into the waste bin at the bottom of the vibrating screen frame with the airflow. The tablets that meet the specifications and have completed the powder screening process are continuously conveyed to the inclined angle during the vibration process until they come into contact with the discharge frame and are discharged one by one through the bottom guide groove. The process is efficient and stable, and the efficient screening process can effectively improve the overall efficiency of the pharmaceutical tablet production process. In this invention, to maintain the quantitative delivery of the filtered tablets, the chain frame is connected to the discharge rack at one end, allowing the discharge rack to stably place the tablets on the chain frame. The tablets are then transported through the inwardly inclined conveying trough inside the chain frame. Simultaneously, during the discharge process, the transmission of the conveyor belt and the discharge efficiency of the discharge rack remain consistent. This, combined with the diversion plates distributed around the conveyor belt, ensures the quantitative delivery of the tablets. The conveyor structure can be replaced at the collection box at the other end of the chain frame to maintain the quantitative delivery process. Alternatively, the collected box can be used to collect the processed tablets stably without needing to be replaced. Attached Figure Description
[0017] Figure 1 This is a schematic diagram of the three-dimensional structure of the tablet press of the present invention; Figure 2 This is a frontal view of the internal structure of the tablet press of the present invention; Figure 3 This is a schematic diagram of the three-dimensional structure of the vibrating screen frame in the screening chamber of the present invention; Figure 4 This is a schematic diagram of the three-dimensional structure of the limiting ring in the screening chamber of the present invention; Figure 5 For the present invention Figure 3 Enlarged structural diagram at point A in the middle; Figure 6 This is a schematic diagram of the three-dimensional structure of the control slider in the screening chamber of the present invention; Figure 7 This is a side view of the conveyor chain structure of the present invention.
[0018] In the diagram: 1. Tableting machine; 101. Outer frame; 102. Collection box; 103. Tableting assembly; 104. Material cylinder; 105. Glass cover; 2. Screening chamber; 201. Fan; 202. Vibrating screen frame; 203. Baffle; 204. Limiting ring; 205. Inner rubber ring; 206. Limiting post; 207. Miniature vibrating motor; 208. Screening cable; 209. Adjustable slider; 210. Double-end motor; 211. Pulley; 212. Slide chute; 213. Discharge rack; 214. Waste bin; 3. Conveyor chain; 301. Chain frame; 302. Conveying trough; 303. Conveyor belt; 304. Diverter plate; 305. Servo motor. Detailed Implementation
[0019] To facilitate the solution of the problem, embodiments of the present invention provide a tableting apparatus with a controllable sieving structure for manufacturing pharmaceutical tablets. The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0020] like Figure 1-2 As shown, a tableting apparatus for manufacturing pharmaceutical tablets with a controllable sieving structure includes a tablet press 1. A sieving chamber 2 is provided inside one side of the tablet press 1, and a conveyor chain 3 is provided at the bottom end of the sieving chamber 2. The tablet press 1 includes an outer frame 101, and a collection box 102 is engaged inside the outer frame 101. A tableting assembly 103 is provided on one side of the top of the outer frame 101, and a material cylinder 104 is connected to the top of the tableting assembly 103. Glass covers 105 are distributed around the tableting assembly 103. To ensure stability during the tablet compression process of tablet press 1 in pharmaceutical tablet manufacturing, an external protective structure is employed to provide stability to the tablet compression process, such as... Figure 1-2As shown, during the tablet manufacturing process of this tablet press 1, the pharmaceutical powder material can be fed into the cylinder 104 and conveyed by the cylinder 104 to the rotary tableting assembly 103 connected to the bottom end for stable and efficient tablet compression. When the tableting assembly 103 is making tablets, the entire structure is within the glass cover 105, which provides protection for the entire assembly, maintains the anti-interference process of tablet making, and reduces the influence of external impurities during the tablet compression process.
[0021] like Figure 2-6 As shown, the screening chamber 2 includes a blower 201, and a vibrating screen frame 202 is provided at the bottom of the blower 201. Baffles 203 are connected to the top surfaces of both sides of the vibrating screen frame 202, and limit rings 204 are distributed at both ends of the baffles 203. An inner rubber ring 205 is fitted to the inner wall of the limit ring 204, and a limit post 206 is fitted inside the inner diameter of the inner rubber ring 205 with a pre-reserved gap. A miniature vibration motor 207 is connected around the bottom of the vibrating screen frame 202. The inner frame is arranged with screening cables 208 in a cross pattern. The two ends of the screening cables 208 are connected to the control sliders 209. The control sliders 209 are equipped with double-end motors 210. The two ends of the double-end motors 210 are connected to pulleys 211. The two sides of the control sliders 209 are arranged with grooves 212 at equal intervals along the inner frame of the vibrating screen frame 202. The vibrating screen frame 202 is equipped with a discharge rack 213 at one end and a waste bin 214 at the bottom of the vibrating screen frame 202. To maintain the overall device's efficient screening, powder removal, and impurity removal processes during discharge and to reduce the complexity of the preparation process, such as... Figure 2-6 As shown, during the tablet feeding process, the tablet compression assembly 103 can create a vibration process through the vibrating screen frame 202 and the connected micro vibration motor 207. This can work in conjunction with the internally connected cross-arranged screening cables 208 to continuously vibrate and screen the conveyed tablets and remove powder and impurities. During the process, the top fan 201 blows air downwards, causing the powder and broken tablets shaken out by the vibrating screen to fall into the waste bin 214 at the bottom of the vibrating screen frame 202 with the airflow. The tablets that meet the specifications and have completed the screening process are continuously conveyed to the inclined angle during the vibration process until they come into contact with the discharge frame 213 and are discharged one by one through the bottom guide channel. The process is efficient and stable, and the vibrating screen process is highly efficient, which can effectively improve the overall efficiency of the pharmaceutical tablet manufacturing process. When the vibrating sieve frame 202 achieves continuous vibrating sieve by relying on the eccentric wheel structure of the micro vibration motor 207, the limiting rings 204 connected on both sides are fitted with the limiting stakes 206 through the inner rubber rings 205 on the inner wall to keep the vibrating sieve range within the limit and avoid large-scale shaking that affects the overall stability of the equipment operation. The sieve cable 208 connected to the inner frame of the vibrating sieve frame 202 is connected to the inner frame slide groove 212 through the two end adjustment sliders 209 and forms a screen by intersecting each other. This screen can be adjusted by the adjustment sliders 209 connected to both ends of the sieve cable 208 in conjunction with the pulleys 211 connected to the double-end motor 210. The distance between the sliding expansion and contraction of multiple sets of adjustment sliders 209 can be controlled to maintain an equidistant state, thereby forming different screen specifications. This can handle round tablets of different sizes and specifications, thus maintaining a controllable sieve process, maintaining high adaptability, and reducing the complexity of the preparation process.
[0022] like Figure 7 As shown, the conveyor chain 3 includes a chain frame 301, and a conveyor groove 302 is provided on the inner wall of the chain frame 301. A conveyor belt 303 is provided in the middle of the conveyor groove 302, and a diverter plate 304 is connected to the outer walls of the conveyor belt 303. A servo motor 305 is connected to both ends of the chain frame 301. To maintain the quantitative delivery of the tablets after sieving, such as Figure 7 As shown, the chain frame 301 is connected to the discharge rack 213 at one end, which allows the discharge rack 213 to stably discharge the tablets onto the chain frame 301. The tablets are conveyed through the inwardly inclined conveying trough 302 inside the chain frame 301. At the same time, during the discharge process, the transmission of the conveyor belt 303 and the discharge efficiency of the discharge rack 213 are kept consistent. This allows the distribution plates 304 distributed around the conveyor belt 303 to quantitatively convey the tablets. The conveying structure can be replaced at the collection box 102 at the other end of the chain frame 301 to maintain the quantitative conveying process. Alternatively, the collection box 102 can be used to collect the processed tablets stably without needing to be replaced.
[0023] In summary, the operation process of this tablet compression device with a controllable sieving structure for pharmaceutical tablet manufacturing includes: When using this tableting device, the powder to be manufactured can be mixed and prepared in advance according to the proportion of tablets to be manufactured. Then, the prepared powder is poured into the tableting assembly 103 through the material cylinder 104. A dust-free environment must be maintained during the process. After the powder enters the tableting assembly 103, the medicine is loaded into the material tray. During the process, the feeding speed is controlled according to the given process parameters. Then, the scraper pushes the excess medicine back into the material tray to ensure that the powder is evenly distributed. Then, the mold rotates and descends to compress the medicine. After the mold is preheated, the machine will distribute sufficient pressure to deform and fix the powder and granular medicine in the space inside the mold to form tablets. Then, the mold rises and opens, and the tablets formed by compression are ejected to the vibrating screen frame 202 below for sieving. Then, the micro vibration motor 207 operates to drive the vibrating screen frame 202 to perform the sieving process. The powder is sieved through the sieve cable 208. Before sieving, the sieve cable 208 needs to be adjusted according to the size of the tablets to be manufactured. The system should be adjusted so that the double-ended motor 210 drives the pulley 211 to rotate, providing power. This causes the control slider 209, where the double-ended motor 210 is located, to slide in the groove 212 of the inner frame of the vibrating screen frame 202, forming an unfolding and shrinking sliding process. During this process, the distance between the control sliders 209 remains equidistant, forming a compliant screening cable 208 after adjustment. Subsequently, the tablets undergo powder removal and impurity removal during continuous screening. The top fan 201 blows a gentle breeze to assist in stabilizing powder removal during tablet vibration. The bottom waste bin 214 can collect and process dust or broken tablets. After completion, the tablets are discharged onto the discharge rack 213 with vibration. The discharge rack 213 then discharges the tablets into the conveying trough 302. The conveyor belt 303 and the distributed diverting plates 304 in the conveying trough 302 divert and quantitatively transport the tablets, which finally fall into the collection box 102 or an alternative conveying structure. Users can continuously remove the tablets or perform periodic collection operations.
[0024] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A tableting apparatus for manufacturing pharmaceutical tablets with a controllable sieving structure, comprising a tablet press (1), characterized in that: The tablet press (1) has a screening chamber (2) inside one side, and a conveyor chain (3) is provided at the bottom of the screening chamber (2). The screening chamber (2) includes a blower (201), and a vibrating screen frame (202) is provided at the bottom of the blower (201). Baffles (203) are connected to the top surfaces of both sides of the vibrating screen frame (202), and limit rings (204) are distributed at both ends of the baffles (203). An inner rubber ring (205) is attached to the inner wall of the limit ring (204), and a limit post (206) is sleeved on the inner diameter of the inner rubber ring (205) with a reserved gap. The bottom of the vibrating screen frame (202) is connected around the perimeter. A miniature vibration motor (207) is provided, and screening cables (208) are arranged in a cross pattern on the inner frame of the vibrating screen frame (202). The two ends of the screening cables (208) are connected to control sliders (209), and a double-ended motor (210) is installed inside the control slider (209). The two ends of the double-ended motor (210) are connected to pulleys (211), and the two sides of the control slider (209) are equidistantly arranged with sliding grooves (212) along the inner frame of the vibrating screen frame (202). A discharge rack (213) is provided at one end of the vibrating screen frame (202), and a waste bin (214) is provided at the bottom of the vibrating screen frame (202). The screening cable (208) and the control slider (209) connected at both ends are arranged in a cross pattern along the slide groove (212) structure of the inner frame of the vibrating screen frame (202), and the screening cable (208) is made of nylon fiber braiding. The control slider (209) slides with the inner frame of the vibrating screen frame (202) through the pulley (211), and the vibrating screen frame (202) is connected and fixed to the two sides of the screening chamber (2) through the micro vibration motors (207) distributed at both ends; The two ends of the vibrating screen frame (202) are fitted onto the outer wall of the limiting pile (206) by limiting rings (204), and the limiting pile (206) is connected and fixed to the two sides of the inner cavity of the screening chamber (2); The tablet press (1) includes an outer frame (101), and a collection box (102) is fitted inside the outer frame (101). A tablet pressing assembly (103) is provided on one side of the top of the outer frame (101), and a material cylinder (104) is connected to the top of the tablet pressing assembly (103). Glass covers (105) are distributed around the tablet pressing assembly (103). The conveyor chain (3) includes a chain frame (301), and a conveyor groove (302) is provided on the inner wall of the chain frame (301). A conveyor belt (303) is provided in the middle of the conveyor groove (302), and a diverter plate (304) is connected to the outer walls of the conveyor belt (303). A servo motor (305) is connected to both ends of the chain frame (301).
2. The tablet compression apparatus with a controllable sieving structure for manufacturing pharmaceutical tablets according to claim 1, characterized in that, The top side of the outer frame (101) is connected and fixed to the glass cover (105) and the tablet pressing assembly (103), and the top of the tablet pressing assembly (103) is connected to the material cylinder (104).
3. The tablet compression apparatus with a controllable sieving structure for manufacturing pharmaceutical tablets according to claim 1, characterized in that, The conveying trough (302) is inclined along the inner walls of both sides of the chain frame (301), and the outer walls of both sides of the chain frame (301) are fixedly connected to the inner walls of both sides of the screening chamber (2).
4. A tablet compression apparatus with a controllable sieving structure for manufacturing pharmaceutical tablets according to claim 1, characterized in that, The conveyor belt (303) has a transmission structure at both ends through a servo motor (305) and a chain frame (301), and the diverter plate (304) is arranged at equal intervals along the outer wall of the conveyor belt (303).
Citation Information
Patent Citations
Medicine powder screening machine
CN112156971A
Medicinal material preforming screening plant
CN205439307U