A preparation method of 3-bromo-2-methoxyaniline
By performing hydrogen reduction reaction in an autoclave and subsequent filtration, extraction, drying and evaporation of the solvent steps, the problem of the 3-bromo-2-methoxyaniline preparation method in the prior art produces a large amount of wastewater and waste sludge, achieving high purity, thermal stability and light stability of the product, which facilitates industrial production and storage and transportation.
Patent Information
- Application Number
- CN202411957836.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-30
- Publication Date
- 2025-04-04
AI Technical Summary
The existing preparation method of 3-bromo-2-methoxyaniline produces a large amount of wastewater and waste sludge, which has a large environmental pressure and increases production costs, making it not suitable for large-scale industrial production.
The reaction was carried out using a dried three-neck flask, hydrazine hydrate and metal catalyst were added, and hydrogen reduction reaction was carried out in an autoclave. The reaction progress was monitored by thin layer chromatography, and the solvent was then filtered, extracted, dried and evaporated to purify 3-bromo-2-methoxyaniline.
The prepared 3-bromo-2-methoxyaniline is stored at room temperature for one month and the purity is maintained above 95% for one month, and the purity is maintained above 80% for one month at 70°C. It has excellent thermal stability and light stability, which is convenient for storage and transportation, and reduces outgoing and storage costs.
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