牛磺石胆酸在制备预防和 / 或治疗动脉粥样硬化药物中的应用
By using various drug formulations prepared with taurine, the problem of adverse drug reactions in existing drugs has been solved, achieving effective prevention and treatment of atherosclerosis, reducing dyslipidemia, and inhibiting plaque formation.
CN119792308BActive Publication Date: 2026-07-17ANHUI UNIV +1
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ANHUI UNIV
- Filing Date
- 2025-03-03
- Publication Date
- 2026-07-17
AI Technical Summary
Technical Problem
Existing drugs for treating atherosclerosis have adverse reactions, and there are no reports on the application of gut microbiota in the prevention and treatment of atherosclerosis.
Method used
Taurol lithocholic acid is used as the active ingredient to prepare drugs in various dosage forms, such as oral liquids, injections, and tablets, for the prevention and treatment of atherosclerosis.
Benefits of technology
It significantly reduces plasma total cholesterol, triglycerides, and low-density lipoprotein, increases high-density lipoprotein, inhibits atherosclerotic plaque formation, and improves symptoms of atherosclerosis.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure CN119792308B_ABST
Abstract
本发明公开了牛磺石胆酸在制备预防和 / 或治疗动脉粥样硬化药物中的应用，本发明属于生物医药领域。本发明中牛磺石胆酸能够降低小鼠主动脉以及主动脉根部粥样斑块面积，调节小鼠血脂水平。动物实验结果证实了牛磺石胆酸对于动脉粥样硬化小鼠主动脉粥样斑块形成具有预防和改善作用。本发明的药物毒性较小，安全性较高。
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