Application of fluorescent probe L5 in detection of elderly male infertility and kit

CN119859682APending Publication Date: 2025-04-22THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN
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Patent Information

Application Number
CN202510355419.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-25
Publication Date
2025-04-22

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Abstract

The invention discloses application of a fluorescent probe L5 in detection of elderly male infertility and a kit, and belongs to the technical field of biotechnology and clinical medicine detection. The inventor team further finds that the fluorescent probe L5 can sensitively detect the elderly male infertility on the basis of early-stage research, so that the application of the fluorescent probe L5 in preparation of a product for detecting the elderly male infertility is provided, and male fertility and male infertility of aged people (namely elderly people) can be obviously distinguished; meanwhile, it is also found that the reagent L5-OA can also sensitively detect the elderly male infertility, so that the application of the reagent L5-OA in preparation of a product for detecting the elderly male infertility is provided, and the detection accuracy of the fluorescent probe L5 is further verified; besides, the reagent L5-OA is toxic to senescent sperms in a sperm sample in detection, so that senescent sperm cells can be effectively removed, the subsequent genetic mutation probability is reduced, and effective prerequisite reference is provided for assisted reproduction.
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Citation Information

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