Genetically engineered bacteria, preparation method thereof, and application thereof in synthesizing resveratrol
CN119875985BActive Publication Date: 2025-08-12TIANJIN ASYMCHEM BIOTECHNOLOGY CO LTD
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Patent Information
- Application Number
- CN202510382497.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-28
- Publication Date
- 2025-08-12
- Estimated Expiration
- 2045-03-28
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Figure CN119875985B_ABST
Abstract
The present invention provides a genetically engineered bacterium, a preparation method thereof, and its use in synthesizing resveratrol. The genetically engineered bacterium contains exogenously introduced p-coumaroyl-CoA ligase gene At4CL from Arabidopsis thaliana and stilbene synthase gene PcSTS from Polygonum cuspidatum; the genetically engineered bacterium is selected from Escherichia coli. The method for synthesizing resveratrol using this genetically engineered bacterium has a short fermentation cycle, high yield, and high production intensity, and has promising application prospects. It lays a foundation for the industrialized production of resveratrol using Escherichia coli microbial fermentation.
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Citation Information
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