Use of vanillyl-beta-d-glucopyranoside in the preparation of a drug for liver injury

Abstract

The application belongs to the technical field of medicine, and particularly relates to application of vanillyl-beta-D-glucopyranoside in preparation of liver injury drugs. The application provides, for the first time, application of vanillyl-beta-D-glucopyranoside in preparation of liver injury drugs. Vanillyl-beta-D-glucopyranoside is Vanillyl-beta-D-glucopyranoside (molecular formula is C 14 H 20 O8; molecular weight is 316.3, and is referred to as VA hereinafter). The drug VA does not show toxicity in a concentration range (6.25-100 muM) under investigation, can significantly improve cell survival rate of liver parenchymal cells AML-12 induced by acetaminophen, has a significant liver protection effect, and has a good application prospect in preparation of liver injury prevention and treatment drugs.

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