Bletilla striata polysaccharide composite particle as well as preparation method and application thereof

The white and polysaccharide composite particles formed by ester bond crosslinking solve the problem of low hemostatic effect caused by poor solubility of baicalin, and achieve efficient blood absorption and suitable for a variety of wound types.

CN119925627APending Publication Date: 2025-05-06GUIZHOU CROP VARIETIES RESOURCE INST
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202510067687.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-16
Publication Date
2025-05-06

AI Technical Summary

Technical Problem

Baicalin in existing wound dressings containing baicalin has poor solubility, resulting in low hemostatic effect efficiency.

Method used

The white and polysaccharide composite particles formed by ester bond crosslinking have a cross-linking degree of 80-90% and a particle size of 300-500nm. They are used to improve the bioavailability of baicalin and blood absorption efficiency.

Benefits of technology

It improves the specific surface area of ​​the particles, enhances the efficiency of contacting the wound and absorbing blood, significantly improves the hemostatic effect, and is suitable for irregular wounds.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119925627A_ABST
    Figure CN119925627A_ABST
Patent Text Reader

Abstract

The invention relates to the technical field of medical materials, in particular to rhizoma bletillae polysaccharide composite particles and a preparation method and application thereof. The rhizoma bletillae polysaccharide and the baicalin are cross-linked through ester bonds to form particles, the cross-linking degree of the rhizoma bletillae polysaccharide and the baicalin is 80-90%, and the particles are nearly spherical. The rhizoma bletillae polysaccharide composite particles are obtained by cross-linking the rhizoma bletillae polysaccharide and the baicalin, so that the bioavailability of the baicalin and the rhizoma bletillae polysaccharide is increased, the particles can be in rapid contact with cells at a wound during use, and the antibacterial, hemostatic and wound repairing effects of the rhizoma bletillae polysaccharide and the baicalin are exerted.
Need to check novelty before this filing date? Find Prior Art