Adjusting method of optical detection equipment and related equipment

By using multiple driving devices and sub-drive components in the optical detection device, the alignment and focus of multiple preset positions is achieved, and the problem of poor leveling and focusing effects in gene sequencing is solved, and the accuracy and automation of sequencing are improved.

CN119932167APending Publication Date: 2025-05-06MGI TECH CO LTD
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Patent Information

Application Number
CN202311462461.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2023-11-06
Publication Date
2025-05-06

AI Technical Summary

Technical Problem

During gene sequencing, the leveling and focusing effects are poor, resulting in low sequencing accuracy and low efficiency.

Method used

A method for adjusting an optical detection device is provided, by adjusting the distance between the carrier device and the optical signal detection device through the first driving device and the second driving device, realizing alignment and focusing of a plurality of preset positions, and fine adjustment is performed using a sub-drive component.

Benefits of technology

Improves the efficiency and accuracy of leveling and focusing, reduces the number of focus times, and enhances the accuracy and automation of gene sequencing.

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Abstract

The invention provides an adjusting method of optical detection equipment, the optical detection equipment, a sequencer and a storage medium. The method comprises the following steps: aligning an optical signal detection device with a first preset position of a to-be-detected sample; controlling the optical signal detection device to start a focusing function, acquiring a focusing signal corresponding to the first preset position, and acquiring a target focusing signal value based on the focusing signal; respectively aligning the optical signal detection device with a plurality of other preset positions of the to-be-detected sample, and acquiring corresponding adjustment displacement of each other preset position in a direction perpendicular to the focusing plane based on the target focusing signal value; and the optical signal detection device adjusts the distance between each other preset position and the optical signal detection device by using each sub-driving part based on the adjustment displacement of each other preset position. According to the method, the leveling and focusing effects can be improved.
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