一种白纹伊蚊aalClk基因及其dsRNA和应用
By screening the aalClk gene of Aedes albopictus and synthesizing dsRNA to silence its expression, the diapause behavior of Aedes albopictus was regulated, which solved the problem of the lack of effective methods for regulating diapause in existing technologies and achieved effective suppression of the Aedes albopictus vector population.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SOUTHERN MEDICAL UNIVERSITY
- Filing Date
- 2025-01-21
- Publication Date
- 2026-07-17
AI Technical Summary
Current technologies lack economical, accurate, efficient, safe, and non-toxic methods to regulate the photoperiodic diapause behavior of Aedes albopictus, which allows it to overwinter and expand, thus affecting the control of vector-borne infectious diseases.
By screening and identifying the aalClk gene in Aedes albopictus, a dsRNA specifically targeting this gene was designed and synthesized. This dsRNA was then introduced into Aedes albopictus to silence the expression of the aalClk gene, thereby regulating its diapause behavior and reducing the diapause rate of offspring eggs.
Under diapause-induced conditions, the diapause rate of Aedes albopictus progeny eggs decreased, making it difficult for them to survive adverse conditions. This effectively suppressed the Aedes albopictus vector population and provided a theoretical basis for novel biological control products.
Smart Images
Figure CN119979548B_ABST