Reagent extraction device, reagent extraction method, and sample analyzer

Abstract

This application discloses a reagent extraction device, a reagent extraction method, and a sample analyzer. The reagent extraction device includes: a reagent module for storing reagents; a sampling component for collecting reagents through a reagent needle; a liquid level detection module for detecting the liquid level height of the reagents; and a control module for: obtaining an initial liquid level height; determining a first height and a second height based on the initial liquid level height; wherein the first height is greater than the initial liquid level height and the second height is less than the initial liquid level height; controlling the liquid level detection module to detect the liquid level height of the reagents in the reagent module to obtain a third height; and responding to a third height that is not less than the second height and not greater than the first height, controlling the needle tip of the reagent needle to move to a position below the third height to extract the reagents, and updating the initial liquid level height based on the third height, thereby improving the reliability of reagent extraction.

Description

Technical Field

[0001] This application relates to the field of detection technology, and in particular to reagent extraction devices, reagent extraction methods and sample analyzers. Background Technology

[0002] In the prior art, reagent needles are typically controlled to extract reagents from reagent modules (such as dye bottles or other types of reagent bottles), and liquid level detection modules are used to determine the liquid level height in the reagent module in order to determine the sampling height of the reagent needle.

[0003] The drawback of existing technologies is that liquid level detection modules are usually devices that use pressure detection, photoelectric detection, radio frequency detection, impedance detection, or capacitance detection to detect the liquid level in the reagent module. However, liquid level detection modules are also prone to failure. If liquid level detection is relied upon solely for liquid level detection, it is easy for the reagent needle to fail to extract the corresponding reagent when the liquid level detection module malfunctions, such as the phenomenon of empty suction, which makes the reliability of reagent extraction poor. Summary of the Invention

[0004] The main technical problem addressed in this application is how to improve the reliability of reagent extraction.

[0005] To solve the above-mentioned technical problems, the first technical solution adopted in this application is: a reagent extraction device, comprising: a reagent module for storing reagents; a sampling component for collecting reagents through a reagent needle; a liquid level detection module for detecting the liquid level height of the reagents; and a control module for: obtaining an initial liquid level height; determining a first height and a second height based on the initial liquid level height; wherein the first height is greater than the initial liquid level height and the second height is less than the initial liquid level height; controlling the liquid level detection module to detect the liquid level height of the reagents in the reagent module to obtain a third height; and responding to a third height that is not less than the second height and not greater than the first height, controlling the needle tip of the reagent needle to move to a position below the third height to extract the reagents, and updating the initial liquid level height based on the third height.

[0006] The method of updating the initial liquid level based on the third height includes: in response to the third height not being greater than the sum of the initial liquid level and the preset error threshold, the initial liquid level is updated to the difference between the third height and the reagent extraction amount height.

[0007] The method of updating the initial liquid level based on the third height further includes: in response to the third height being greater than the sum of the initial liquid level and the preset error threshold, updating the initial liquid level to the difference between the initial liquid level and the reagent extraction height.

[0008] In this process, after the control liquid level detection module detects the liquid level height of the reagent in the reagent module and obtains the third height, the control module is also used to: respond to the third height being greater than the first height, control the needle tip of the reagent needle to move to a position below the second height to extract the reagent, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0009] The method of controlling the reagent needle to move to a position below the second height in response to the third height being greater than the first height includes: controlling the liquid level detection module to re-detect the liquid level of the reagent in the reagent module and update the third height in response to the third height being greater than the first height; and controlling the reagent needle to move to a position below the second height in response to the updated third height being greater than the first height in response to the reagent extraction.

[0010] The control module is also used to: respond to the situation where no reagent is detected when the reagent needle moves down to the second height, control the needle tip of the reagent needle to move to a position below the second height to extract the reagent, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0011] The liquid level detection module is used to detect whether the needle tip of the reagent needle touches the reagent, obtain the touch detection result, and determine the liquid level height of the reagent based on the touch detection result. Controlling the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height includes: responding to the reagent needle not being detected when it moves down to the second height, controlling the reagent needle to continue moving down before reaching the preset minimum liquid level, until the liquid level detection module detects the reagent, thus obtaining the third height; the control module is also used to: if no reagent is detected when the reagent needle reaches the preset minimum liquid level, output an alarm indication indicating that the liquid volume is empty; if the liquid level detection module detects the reagent before the reagent needle reaches the preset minimum liquid level, thus obtaining the third height, control the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0012] The determination of the first height and the second height based on the initial liquid level includes: adding the reagent extraction height to the initial liquid level to obtain a target sum; multiplying the target sum by a first preset ratio to obtain the first height; and / or subtracting the reagent extraction height from the initial liquid level to obtain a target difference; multiplying the target difference by a second preset ratio to obtain the second height; both the first preset ratio and the second preset ratio are greater than 0 and not greater than 1.

[0013] To solve the above-mentioned technical problems, the second technical solution adopted in this application is: a reagent extraction method applied to the above-mentioned reagent extraction device; the reagent extraction method includes: obtaining an initial liquid level height; determining a first height and a second height based on the initial liquid level height; the first height being greater than the initial liquid level height and the second height being less than the initial liquid level height; controlling a liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; in response to the third height being not less than the second height and not greater than the first height, controlling the needle tip of the reagent needle to move to a position below the third height to extract the reagent, and updating the initial liquid level height based on the third height.

[0014] To solve the above-mentioned technical problems, the third technical solution adopted in this application is: a sample analyzer, including the above-mentioned reagent extraction device.

[0015] The beneficial effects of this application are as follows: Unlike the prior art, the reagent extraction device in this application includes a reagent module, a sampling component, a liquid level detection module, and a control module. The control module is used to: obtain an initial liquid level height; determine a first height and a second height based on the initial liquid level height; control the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; and, in response to the third height being not less than the second height and not greater than the first height, control the needle of the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height based on the third height. Based on the above method, the detection result obtained by the liquid level detection module can be considered reliable only when it is determined that the third height obtained by the liquid level detection module is between the first height and the second height. The reagent needle can be controlled to move to a position below the third height to extract the reagent, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction. This improves the accuracy of the initial liquid level height and the probability that the reagent needle can extract the required reagent, thereby improving the reliability of reagent extraction. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the structure of one embodiment of the reagent extraction device of this application;

[0018] Figure 2 This is a schematic flowchart of an embodiment of the reagent extraction method of this application;

[0019] Figure 3 This is a schematic diagram of the structure of one embodiment of the sample analyzer of this application.

[0020] The components include: reagent module 11, sampling component 12, liquid level detection module 13, control module 14, sample analyzer 20, and reagent extraction device 21. Detailed Implementation

[0021] The present application will now be described in further detail with reference to the accompanying drawings and embodiments. It should be particularly noted that the following embodiments are for illustrative purposes only and do not limit the scope of the application. Similarly, the following embodiments are only some, not all, embodiments of the present application, and all other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of the present application.

[0022] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a mutually exclusive, independent, or alternative embodiment. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0023] In the description of this application, it is necessary to specify that, unless otherwise expressly stated and limited, the terms "installation," "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or a connection through an intermediate medium. Those skilled in the art will understand the specific meanings of the above terms within the context of this application.

[0024] This application first proposes a reagent extraction device, see [link to previous document]. Figure 1 , Figure 1 This is a schematic diagram of the structure of one embodiment of the reagent extraction device of this application, as shown below. Figure 1 As shown, the reagent extraction device includes a reagent module 11, a sampling component 12, a liquid level detection module 13, and a control module 14.

[0025] The reagent module 11 is used to store reagents. Specifically, the reagent module 11 can be a reagent bottle or other type of container for storing reagents. The reagents can be dye solutions or other types of reagents that can be used for sample detection, which are not limited here.

[0026] The sampling component 12 is used to collect reagents via the reagent needle 121. The sampling component 12 may include a sampling motor and a reagent needle 121. The sampling motor can be used to control the movement of the reagent needle 121, for example, controlling the tip of the reagent needle 121 to enter or leave the reagent within the reagent module 11.

[0027] The liquid level detection module 13 is used to detect the liquid level height of the reagent. Specifically, the liquid level detection module 13 can be a module based on pressure detection method. In this way, a pressure sensor is used to sense the pressure change in the reagent needle 121 or the pipeline connected to the reagent needle 121 to determine whether the needle tip of the reagent needle 121 has touched the liquid surface. The liquid level height of the reagent is determined by combining the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when it touches the liquid surface.

[0028] The liquid level detection module 13 can also be a module that uses photoelectric detection to detect the liquid level. Specifically, a photoelectric sensor is set on the reagent needle 121 near the needle tip to determine whether the needle tip of the reagent needle 121 has touched the liquid surface by sensing the degree of change in reflected light. The liquid level height of the reagent is determined by combining the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when it touches the liquid surface.

[0029] The liquid level detection module 13 can also be a module that uses radio frequency detection to detect the liquid level. Specifically, a radio frequency signal transmitter and receiver are set on the reagent needle 121 near the needle tip. The degree of change of the received radio frequency signal is used to determine whether the needle tip of the reagent needle 121 has touched the liquid surface. The liquid level height of the reagent is determined by combining the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when it touches the liquid surface.

[0030] The liquid level detection module 13 can also be a module that uses impedance detection to detect the liquid level. Specifically, the reagent needle has two interconnected needles. By determining the impedance change between the two needles, it is determined whether the needle of the reagent needle 121 touches the liquid surface. The liquid level height of the reagent is determined by combining the initial height of the needle of the reagent needle 121 and the height of the needle when it touches the liquid surface.

[0031] The liquid level detection module 13 can also be a module that uses capacitance detection to detect the liquid level. Specifically, the reagent needle 121 is used as a variable capacitor, and capacitance detection is performed on the variable capacitor. The change in capacitance determines whether the tip of the reagent needle 121 touches the liquid surface. The liquid level height of the reagent is determined by combining the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when it touches the liquid surface.

[0032] In one example, if the liquid level detection module 13 is a module that uses capacitance detection to detect the liquid level, then the liquid level detection module 13 may include a detection circuit, a judgment circuit, and a first control circuit.

[0033] The detection circuit is connected to a reagent needle, which is a capacitive reagent needle. The detection circuit is configured to input a detection signal and output a target voltage signal. The detection signal is determined by the contact condition between the capacitive reagent needle and the liquid surface.

[0034] The judgment circuit is connected to the detection circuit. The judgment circuit is configured to input the target voltage signal and the reference voltage signal, to judge the magnitude relationship between the target voltage signal and the reference voltage signal, and to output a judgment result signal.

[0035] A first control circuit is connected to the judgment circuit, and the first control circuit is configured to control the reagent needle to perform sampling based on the judgment result signal.

[0036] Based on the above method, the detection signal used to characterize the contact between the capacitive reagent needle and the liquid surface can be further processed to determine whether the capacitive reagent needle is in contact with the liquid surface. The liquid surface height of the reagent can be determined by combining the initial height of the needle tip of the reagent needle 121 and the height of the needle tip when it touches the liquid surface, thereby realizing liquid surface detection.

[0037] Control module 14 is used for:

[0038] Obtain the initial liquid level. Specifically, when the reagent module 11 has not yet undergone reagent extraction, the initial liquid level can be the theoretical initial height of the reagent within the reagent module 11. When the reagent module 11 has undergone reagent extraction, the initial liquid level can be the initial liquid level determined during the last reagent extraction of the reagent module 11.

[0039] Based on the initial liquid level, a first height and a second height are determined. The first height is greater than the initial liquid level, and the second height is less than the initial liquid level. That is, the order from lowest to highest is second height - initial liquid level - first height.

[0040] In one example, the first height and the second height can be obtained based on the initial liquid level height and a preset difference, and the first height can be determined based on the sum of the initial liquid level height and the preset difference, while the second height can be determined based on the difference between the initial liquid level height and the preset difference. This preset difference can be set according to actual application requirements and is not limited here. Optionally, the difference between the initial liquid level height and the first height, and the difference between the initial liquid level height and the second height, can also be different.

[0041] In one example, the first height can be determined based on the sum of the initial liquid level and the reagent extraction height, and the second height can be determined based on the difference between the initial liquid level and the reagent extraction height. The reagent extraction height is specifically the expected decrease in the reagent level after reagent extraction, and this height is specifically related to the amount of reagent to be extracted and the shape characteristics of the reagent bottle. Optionally, at least one of the difference between the initial liquid level and the first height, and the difference between the initial liquid level and the second height, is less than the reagent extraction height. In other examples, the first and second heights corresponding to the initial liquid level can be determined in other ways, which are not limited here.

[0042] The liquid level detection module 13 controls the detection of the liquid level of the reagent in the reagent module 11 to obtain the third height.

[0043] The reagent needle 121 can be controlled to move toward the reagent, and the liquid level detection module 13 determines whether the reagent needle 121 touches the liquid surface, thereby determining the liquid level height.

[0044] In response to the third height being not less than the second height and not greater than the first height, the needle of the reagent needle 121 is moved to a position below the third height to extract the reagent, and the initial liquid level is updated based on the third height.

[0045] If the reagent needle 121 touches the liquid surface when the needle tip moves to the area between the second height and the first height, thus obtaining the third height, then the value of the third height can be considered to be within the expected range, that is, the reliability of the third height is high. Therefore, at this time, the needle tip of the reagent needle 121 can be controlled to move to a position below the third height to extract the reagent, thus realizing the reagent extraction. The initial liquid level can be updated based on the third height to provide a more accurate initial liquid level for the next reagent extraction, thereby improving the success rate of the next reagent extraction. In summary, the reliability of reagent extraction is improved.

[0046] It should be noted that, in one example, the position below the third height mentioned above can specifically be a position that changes as the liquid level of the reagent decreases, such as a position below the third height mentioned above and always at a distance of a preset height threshold from the liquid level of the reagent, or other positions below the third height mentioned above and always below the liquid level of the reagent, which are not limited here.

[0047] In other examples, the position below the third height mentioned above can also be the position at the height obtained by subtracting the preset height threshold from the third height and then subtracting the reagent extraction height. The preset height threshold can be determined according to actual needs and is not limited here.

[0048] Unlike existing technologies, the reagent extraction device in this application includes a reagent module, a sampling component, a liquid level detection module, and a control module. The control module is used to: obtain an initial liquid level height; determine a first height and a second height based on the initial liquid level height; control the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; and, in response to the third height being not less than the second height and not greater than the first height, control the needle tip of the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height based on the third height. Based on the above method, the detection result obtained by the liquid level detection module can be considered reliable only when it is determined that the third height obtained by the liquid level detection module is between the first and second heights. The reagent needle can then be controlled to move to a position below the third height to extract the reagent, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction. This improves the accuracy of the initial liquid level height and the probability that the reagent needle can extract the required reagent, thereby improving the reliability of reagent extraction.

[0049] In one embodiment, updating the initial liquid level based on a third height includes:

[0050] If the third height is not greater than the sum of the initial liquid level and the preset error threshold, the initial liquid level is updated to the difference between the third height and the reagent extraction height.

[0051] Specifically, when the detected third height is not greater than the sum of the initial liquid level height and the preset error threshold, it can be considered that the third height obtained by the liquid level detection module 13 is highly reliable and accurate. Therefore, the initial liquid level height can be updated to the difference between the third height and the reagent extraction height. That is, the difference obtained by subtracting the height by which the reagent liquid level will drop when the reagent is extracted from the third height detected by the liquid level detection module 13 is used as the new initial liquid level height, and the update is completed.

[0052] In one example, the preset error threshold is less than the difference between the initial liquid level height and the first height, and / or, the preset error threshold is less than the difference between the initial liquid level height and the second height.

[0053] Based on the above method, when the third height is not greater than the sum of the initial liquid level and the preset error threshold, the accuracy of the detected third height is considered to be relatively high, and the initial liquid level is updated accordingly, thereby improving the reliability of reagent extraction.

[0054] Optionally, updating the initial liquid level based on the third height also includes:

[0055] If the third height is greater than the sum of the initial liquid level height and the preset error threshold, the initial liquid level height is updated to the difference between the initial liquid level height and the reagent extraction height.

[0056] Specifically, under normal circumstances, the third height should usually be greater than the initial liquid level. Even if there is an error, it will not be too large. Therefore, when the detected third height is greater than the sum of the initial liquid level and the preset error threshold, it can be considered that the accuracy of the detected third height is low. It may be affected by bubbles on the reagent surface, which may lead to inaccurate detection. Therefore, the third height obtained by the liquid level detection module 13 can be ignored at this time. Instead, the reagent extraction height is subtracted from the initial liquid level to obtain the corresponding difference. The initial liquid level is then updated to this difference to provide a more accurate initial liquid level for the next reagent extraction, thereby improving the success rate of the next reagent extraction, reducing the possibility of reagent extraction errors caused by using an inaccurate third height to update the initial liquid level, and improving the reliability of reagent extraction.

[0057] In one embodiment, after the control liquid level detection module 13 detects the liquid level height of the reagent in the reagent module 11 and obtains the third height, the control module 14 is further configured to:

[0058] In response to the third height being greater than the first height, the needle of the reagent needle 121 is moved to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

[0059] Specifically, when a liquid surface is detected at a position higher than the first height, it is considered that the detection result of the liquid surface detection module 13 may be incorrect, possibly due to the influence of air bubbles or other factors on the reagent surface, leading to inaccurate detection. To ensure successful reagent extraction, the needle of the reagent needle 121 can be moved to a position below the lowest second height for reagent extraction. This reduces the possibility of reagent extraction failure due to inaccurate third height. Simultaneously, the third height obtained by the liquid surface detection module 13 can be ignored at this time. Instead, the reagent extraction height is subtracted from the initial liquid surface height to obtain the corresponding difference, and the initial liquid surface height is updated to this difference. This provides a more accurate initial liquid surface height for the next reagent extraction, improving the success rate and reliability of the next extraction. This technical solution, by combining the calculated height range with the liquid surface detection function of the hardware module, can reduce false alarms caused by interference from other environmental factors, the need for secondary detection, and the impact of false alarms on test results, thereby improving the reliability of liquid surface detection and reagent extraction.

[0060] It should be noted that the position below the second height mentioned above can be the position obtained by subtracting the preset height threshold from the second height and then subtracting the reagent extraction height. The preset height threshold can be determined according to actual needs and is not limited here.

[0061] In addition, when the third height is detected to be greater than the first height, a false detection of liquid level or premature liquid contact can be indicated. Maintenance personnel can then perform an inspection based on the indication, or only perform an inspection when the number of indications exceeds a preset threshold.

[0062] Optionally, in response to the third height being greater than the first height, the needle tip of the reagent needle 121 is moved to a position below the second height for reagent extraction, including:

[0063] If the third height is greater than the first height, the liquid level detection module 13 is controlled to re-detect the liquid level of the reagent in the reagent module 11 and update the third height.

[0064] In response to the updated third height being greater than the first height, the needle tip of the reagent needle 121 is moved to a position below the second height to extract the reagent.

[0065] Specifically, when the third height is detected to be greater than the first height, it can be considered that the detection result of the liquid level detection module 13 may be incorrect, so the liquid level detection module 13 can be controlled to re-detect the liquid level height.

[0066] If the result of re-detecting the liquid level is that the third height is not greater than the first height and not less than the second height, then the needle of reagent needle 121 can be moved to a position below the third height to extract the reagent, and the initial liquid level can be updated based on the third height.

[0067] If the result of re-detecting the liquid level is that no reagent is detected when the reagent needle moves down to the second height, the needle tip of reagent needle 121 can be controlled to move to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

[0068] If the result of the retest of the liquid level height is still that the third height is greater than the first height, it can be finally determined that the detection result of the liquid level detection module 13 may be wrong. It may be affected by bubbles on the surface of the reagent, which may lead to inaccurate detection. In other words, based on more than two repeated tests, it is highly likely that the detection result of the liquid level detection module 13 is wrong.

[0069] At this time, the needle tip of the controllable reagent needle 121 can be moved to a position below the lowest second height to extract the reagent, reducing the possibility of reagent extraction failure due to inaccurate third height and improving the reliability of reagent extraction.

[0070] In one embodiment, the control module 14 is further configured to:

[0071] If no reagent is detected when the reagent needle moves down to the second height, the needle tip of the reagent needle 121 is controlled to move to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

[0072] Specifically, if the reagent needle is moved down to the second height and no reagent is detected, it can be assumed that the detection result of the liquid level detection module 13 may be incorrect. To ensure the successful extraction of reagent, the needle of the reagent needle 121 can be moved to a position below the lowest second height for reagent extraction. This reduces the possibility of reagent extraction failure due to inaccurate third height. At the same time, the third height obtained by the liquid level detection module 13 can be ignored at this time. Instead, the reagent extraction height is subtracted from the initial liquid level height to obtain the corresponding difference. The initial liquid level height is then updated to this difference to provide a more accurate initial liquid level height for the next reagent extraction, thereby improving the success rate of the next reagent extraction and increasing the reliability of reagent extraction.

[0073] It should be noted that the position below the second height mentioned above can be the position obtained by subtracting the preset height threshold from the second height and then subtracting the reagent extraction height. The preset height threshold can be determined according to actual needs and is not limited here.

[0074] In addition, if the third height is detected to be lower than the second height, it can also indicate that the reagent supply is insufficient. Maintenance personnel can check according to the prompt, or check only when the number of prompts exceeds the preset threshold.

[0075] In one embodiment, the liquid level detection module 13 is used to detect whether the needle tip of the reagent needle 121 touches the reagent, obtain the touch detection result, and determine the liquid level height of the reagent based on the touch detection result.

[0076] The liquid level detection module 13 controls the detection of the liquid level of the reagent in the reagent module 11 to obtain a third height, including:

[0077] If no reagent is detected when the reagent needle 121 moves down to the second height, the reagent needle 121 is controlled to continue moving down before reaching the preset minimum liquid level, until the liquid level detection module 13 detects the reagent and obtains the third height.

[0078] The control module is also used for:

[0079] If no reagent is detected when reagent needle 121 reaches the preset minimum liquid level, an alarm indication indicating that the liquid volume is empty will be output.

[0080] If the liquid level detection module 13 detects the reagent before the reagent needle 121 reaches the preset minimum liquid level and obtains the third height, it controls the reagent needle 121 to move to a position below the third height to extract the reagent, and updates the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

[0081] Specifically, when the needle tip of the reagent needle 121 moves to the second height, if the liquid level detection module 13 has not yet detected that the reagent needle 121 has touched the liquid surface of the reagent, it can be determined that the third height is below the second height. At this time, the reagent needle 121 can be controlled to continue moving towards the preset lowest liquid level of the reagent storage cavity in the reagent module 11.

[0082] If the reagent needle 121 touches the reagent before moving to the preset minimum liquid level, the third height is determined, and the needle tip of the reagent needle 121 is controlled to move to a position below the third height to extract the reagent. The initial liquid level is then updated to the difference between the initial liquid level and the reagent extraction height.

[0083] If the reagent needle 121 fails to touch the reagent when it moves to the preset minimum liquid level, a message indicating that the reagent is empty will be output. Maintenance personnel can check according to the message, or check only when the number of messages exceeds the preset threshold.

[0084] It should be noted that the preset minimum liquid level height can be determined according to the reagent extraction height corresponding to this reagent extraction, and is not limited here. In one example, the preset minimum liquid level can be no less than the reagent extraction height.

[0085] In one embodiment, determining a first height and a second height based on the initial liquid level and the reagent extraction height includes:

[0086] Add the initial liquid level height to the reagent extraction height to obtain the target value.

[0087] Multiply the target value by the first preset ratio to obtain the first height.

[0088] And / or,

[0089] The target difference is obtained by subtracting the reagent extraction height from the initial liquid level height.

[0090] Multiply the target difference by the second preset ratio to obtain the second height.

[0091] The first preset ratio and the second preset ratio are both greater than 0 and not greater than 1.

[0092] Specifically, the first preset ratio can be 70%, 80%, 90%, 100%, or other ratios, and the second preset ratio can be 70%, 80%, 90%, 100%, or other ratios. The specific ratio can be determined according to actual needs and is not limited here.

[0093] Based on the above method, the determined first height and second height can be controlled by preset first and second preset ratios, so that the actual first height and second height determined based on the initial liquid level height are more consistent with the expectation, thereby improving the accuracy of the initial liquid level height updated based on the third height when the third height is not less than the second height and not greater than the first height, thus improving the reliability of subsequent reagent extraction.

[0094] This application proposes a reagent extraction method, which can be applied to the reagent extraction apparatus described in any of the preceding embodiments. See also... Figure 2 , Figure 2 This is a schematic flowchart of an embodiment of the reagent extraction method of this application, as shown below. Figure 2 As shown, the reagent extraction method includes:

[0095] Step S11: Obtain the initial liquid level height.

[0096] Step S12: Based on the initial liquid level, determine the first height and the second height. The first height is greater than the initial liquid level, and the second height is less than the initial liquid level.

[0097] Step S13: Control the liquid level detection module 13 to detect the liquid level height of the reagent in the reagent module 11, and obtain the third height.

[0098] Step S14: In response to the third height being not less than the second height and not greater than the first height, the needle of the reagent needle 121 is moved to a position below the third height to extract the reagent, and the initial liquid level is updated based on the third height.

[0099] Unlike existing technologies, the reagent extraction device in this application includes a reagent module, a sampling component, a liquid level detection module, and a control module. The control module is used to: obtain an initial liquid level height; determine a first height and a second height based on the initial liquid level height; control the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; and, in response to the third height being not less than the second height and not greater than the first height, control the needle tip of the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height based on the third height. Based on the above method, the detection result obtained by the liquid level detection module can be considered reliable only when it is determined that the third height obtained by the liquid level detection module is between the first and second heights. The reagent needle can then be controlled to move to a position below the third height to extract the reagent, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction. This improves the accuracy of the initial liquid level height and the probability that the reagent needle can extract the required reagent, thereby improving the reliability of reagent extraction.

[0100] In one embodiment, such as Figure 2 As shown, after step S13, the reagent extraction method may further include:

[0101] Step S15: In response to the third height being greater than the first height, the needle of the reagent needle 121 is moved to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

[0102] In one embodiment, such as Figure 2 As shown, after step S13, the reagent extraction method may further include:

[0103] Step S16: In response to the fact that no reagent is detected when the reagent needle moves down to the second height, the needle tip of the reagent needle 121 is controlled to move to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

[0104] It should be noted that the reagent extraction method may also include the steps performed by the control module 14 of the reagent extraction device described in any of the preceding embodiments, which will not be repeated here.

[0105] This application proposes a sample analyzer, see [link to relevant documentation] Figure 3 , Figure 3 This is a schematic diagram of the structure of one embodiment of the sample analyzer of this application, as shown below. Figure 3 As shown, the sample analyzer 20 includes a reagent extraction device 21, which can be any of the reagent extraction devices described in the previous embodiments, and will not be repeated here.

[0106] Unlike existing technologies, the reagent extraction device in this application includes a reagent module, a sampling component, a liquid level detection module, and a control module. The control module is used to: obtain an initial liquid level height; determine a first height and a second height based on the initial liquid level height; control the liquid level detection module to detect the liquid level height of the reagent in the reagent module to obtain a third height; and, in response to the third height being not less than the second height and not greater than the first height, control the needle tip of the reagent needle to move to a position below the third height to extract the reagent, and update the initial liquid level height based on the third height. Based on the above method, the detection result obtained by the liquid level detection module can be considered reliable only when it is determined that the third height obtained by the liquid level detection module is between the first and second heights. The reagent needle can then be controlled to move to a position below the third height to extract the reagent, and the initial liquid level height can be updated based on the third height for use in the next reagent extraction. This improves the accuracy of the initial liquid level height and the probability that the reagent needle can extract the required reagent, thereby improving the reliability of reagent extraction.

[0107] In the description of this application, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0108] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0109] Any process or method described in the flowchart or otherwise herein can be understood as representing a module, segment, or portion of code comprising one or more executable instructions for implementing a particular logical function or process, and the scope of the preferred embodiments of this application includes additional implementations in which functions may be performed not in the order shown or discussed, including substantially simultaneously or in reverse order depending on the function involved, as will be understood by those skilled in the art to which embodiments of this application pertain.

[0110] The logic and / or steps represented in the flowchart or otherwise described herein, for example, can be considered as a ordered list of executable instructions for implementing logical functions, and can be embodied in any computer-readable medium for use by, or in conjunction with, an instruction execution system, apparatus, or device (which may be a personal computer, server, network device, or other system that can fetch and execute instructions from, an instruction execution system, apparatus, or device). For the purposes of this specification, "computer-readable medium" can be any means that can contain, store, communicate, propagate, or transmit programs for use by, or in conjunction with, an instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of computer-readable media include: an electrical connection having one or more wires (electronic device), a portable computer disk drive (magnetic device), random access memory (RAM), read-only memory (ROM), erasable and editable read-only memory (EPROM or flash memory), fiber optic devices, and portable optical disc read-only memory (CDROM). Alternatively, the computer-readable medium may be paper or other suitable media on which the program can be printed, since the program can be obtained electronically, for example, by optically scanning the paper or other medium, followed by editing, interpreting, or otherwise processing as necessary, and then stored in a computer memory.

[0111] The above description is merely an embodiment of this application and does not limit the patent scope of this application. Any equivalent structural or procedural transformations made using the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this application.

Claims

1. A reagent extraction device, characterized in that, include: Reagent module, the reagent module being used to store reagents; A sampling component, the sampling component being used to collect samples from the reagent; A liquid level detection module, which is used to detect the liquid level height of the reagent; The control module is used for: Obtain the initial liquid level height; Based on the initial liquid level, a first height and a second height are determined; wherein the first height is greater than the initial liquid level, and the second height is less than the initial liquid level. The liquid level detection module is controlled to detect the liquid level height of the reagent in the reagent module to obtain a third height; In response to the third height being not less than the second height and the third height being not greater than the first height, the needle tip of the reagent needle is controlled to move to a position below the third height to extract the reagent, and the initial liquid level is updated based on the third height. Wherein, after the control module detects the liquid level of the reagent in the reagent module and obtains the third height, the control module is further configured to: In response to the third height being greater than the first height, the needle tip of the reagent needle is controlled to move to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

2. The reagent extraction apparatus according to claim 1, characterized in that, The update of the initial liquid level height based on the third height includes: If the third height is not greater than the sum of the initial liquid level height and the preset error threshold, the initial liquid level height is updated to the difference between the third height and the reagent extraction height.

3. The reagent extraction apparatus according to claim 2, characterized in that, The update of the initial liquid level height based on the third height further includes: In response to the third height being greater than the sum of the initial liquid level height and the preset error threshold, the initial liquid level height is updated to the difference between the initial liquid level height and the reagent extraction height.

4. The reagent extraction apparatus according to claim 1, characterized in that, The step of controlling the needle tip of the reagent needle to move to a position below the second height to extract the reagent in response to the third height being greater than the first height includes: In response to the third height being greater than the first height, the liquid level detection module is controlled to re-detect the liquid level of the reagent in the reagent module and update the third height; In response to the updated third height being greater than the first height, the needle tip of the reagent needle is controlled to move to a position below the second height to extract the reagent.

5. The reagent extraction apparatus according to any one of claims 1 to 3, characterized in that, The control module is also used for: If the reagent is not detected when the reagent needle moves down to the second height, the needle tip of the reagent needle is controlled to move to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

6. The reagent extraction apparatus according to any one of claims 1 to 3, characterized in that, The liquid level detection module is used to detect whether the needle tip of the reagent needle touches the reagent, obtain the touch detection result, and determine the liquid level height of the reagent based on the touch detection result; The control of the liquid level detection module to detect the liquid level height of the reagent in the reagent module and obtain a third height includes: If the reagent needle is not detected when it moves down to the second height, the reagent needle is controlled to continue moving down before reaching the preset minimum liquid level, until the liquid level detection module detects the reagent, and the third height is obtained. The control module is also used for: If the reagent is not detected when the reagent needle reaches the preset minimum liquid level, an alarm indication indicating that the liquid volume is empty is output. If the liquid level detection module detects the reagent before the reagent needle reaches the preset minimum liquid level and obtains the third height, it controls the reagent needle to move to a position below the third height to extract the reagent, and updates the initial liquid level height to the difference between the initial liquid level height and the reagent extraction height.

7. The reagent extraction apparatus according to any one of claims 1 to 3, characterized in that, The process of determining the first height and the second height based on the initial liquid level includes: Add the reagent extraction height to the initial liquid level to obtain the target value; Multiply the target value by a first preset ratio to obtain the first height; And / or, The target difference is obtained by subtracting the reagent extraction height from the initial liquid level height. Multiply the target difference by a second preset ratio to obtain the second height; Wherein, both the first preset ratio and the second preset ratio are greater than 0 and not greater than 1.

8. A reagent extraction method, characterized in that, Applied to the reagent extraction apparatus as described in any one of claims 1 to 7; The reagent extraction method includes: Obtain the initial liquid level height; Based on the initial liquid level, a first height and a second height are determined; wherein the first height is greater than the initial liquid level, and the second height is less than the initial liquid level. The liquid level detection module is controlled to detect the liquid level height of the reagent in the reagent module to obtain a third height; In response to the third height being not less than the second height and the third height being not greater than the first height, the needle tip of the reagent needle is controlled to move to a position below the third height to extract the reagent, and the initial liquid level is updated based on the third height. The reagent extraction method further includes, after the liquid level detection module detects the liquid level height of the reagent in the reagent module and obtains the third height, the reagent extraction method further includes: In response to the third height being greater than the first height, the needle tip of the reagent needle is controlled to move to a position below the second height to extract the reagent, and the initial liquid level is updated to the difference between the initial liquid level and the reagent extraction height.

9. A sample analyzer, characterized in that, Includes the reagent extraction apparatus as described in any one of claims 1 to 7.

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