A gene sequencer

Abstract

This invention provides a gene sequencer, including a frame, a rotating stand, a drug injection mechanism, a clamping assembly, and a driving device. The rotating stand is rotatably mounted on the frame. Multiple drug injection mechanisms are arranged circumferentially on the rotating stand, and each mechanism is used to load drugs. The clamping assembly is mounted on the frame, located directly below one of the drug injection mechanisms, and is used to clamp a gene chip. The clamping assembly can be configured according to existing technology. The driving device drives the rotating stand to rotate and also drives the drug injection mechanisms to quantitatively inject drugs downwards onto the gene chip. This invention, by driving the rotating stand to rotate, allows different drug injection mechanisms to rotate sequentially above the gene chip, and by driving the drug injection mechanisms to quantitatively inject drugs downwards onto the gene chip, thereby reducing operational requirements and improving sequencing efficiency.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a gene sequencer. Background Technology

[0002] Gene sequencers, also known as DNA sequencers, are instruments used to determine the base sequence, type, and quantification of DNA fragments. Currently, gene sequencing development mainly revolves around gene chips, while gene sequencers used in clinical or research settings are primarily large-scale factory-grade or desktop sequencers. These require manual sample loading, and quantitative sample loading with reagents demands high operator skill, leading to reduced sequencing efficiency. Summary of the Invention

[0003] In view of the shortcomings of the prior art, the present invention provides a gene sequencer that can solve or at least alleviate one or more of the above-mentioned problems and other problems existing in the prior art.

[0004] This invention provides a gene sequencer, comprising: frame: A rotating base, which is rotatably mounted on the frame; A drug injection mechanism is provided, wherein multiple drug injection mechanisms are arranged circumferentially on the rotating seat, and the drug injection mechanism is used to load the drug; A clamping assembly, disposed on the frame and located directly below one of the drug injection mechanisms, the clamping assembly being used to clamp the gene chip; and A driving device is used to drive the rotating seat to rotate, and the driving device is also used to drive the drug injection mechanism to inject the drug downwards into the gene chip in a quantitative manner.

[0005] Preferably, the rotating base has a plurality of first holes distributed circumferentially; the first holes penetrate vertically, and each first hole has an inwardly contracting limiting ring at its lower end; The drug injection mechanism includes: The cylinder is mounted on the rotating seat, and its lower end is inserted into the corresponding first hole and abuts against the limiting ring. The needle, connected to the lower end of the cylinder, can rotate and move above the gene chip with the rotating base; and The piston is slidably disposed inside the cylinder and dynamically seals against the inner wall of the cylinder. The drive device can drive the piston to slide inside the cylinder.

[0006] Preferably, the driving device includes a driving mechanism and a plurality of transmission mechanisms; each of the transmission mechanisms corresponds to one of the cylinders; The transmission mechanism includes: A transmission plate, wherein a second hole is provided on the transmission plate, and the transmission plate is slidably mounted on the rotating seat in a vertical direction; A transmission rod is connected to the corresponding piston, and the transmission rod has multiple locking grooves evenly distributed vertically. A mounting base is provided on the transmission plate; and The locking block has a connecting end, a hanging end, and a locking end. The connecting end of the locking block is rotatably connected to the mounting base. The hanging end of the locking block is located below the connecting end of the locking block. The locking end of the locking block is located on one side of the line connecting its connecting end and the hanging end. The locking end of the locking block abuts against the outer wall of the transmission rod and can be inserted into the corresponding locking groove. The distance from the connecting end of the locking block to the locking end of the locking block is greater than the distance between the connecting end of the locking block and the transmission rod; the driving mechanism is used to drive the transmission plate to slide up and down; the driving mechanism is also used to drive the rotating seat to rotate.

[0007] Preferably, the multiple locking slots evenly distributed vertically on the transmission rod form a row; the locking slots on the transmission rod have two or more rows; the number of mounting seats and the number of locking blocks correspond to the number of rows of locking slots; the locking slots in different rows are staggered vertically.

[0008] Preferably, the rotating seat is cylindrical; the axis of the rotating seat is parallel to the axis of the first hole; a vertical first groove is formed on the outer wall of the rotating seat corresponding to each of the first holes; an inclined second groove is formed between two adjacent first grooves; the second groove has a deeper end and a shallower end; the deeper end of the second groove communicates with the lower end of an adjacent first groove, and the depth of the deeper end of the second groove is greater than the depth of the lower end of the first groove; the shallower end of the second groove communicates with the upper end of another adjacent first groove, and the depth of the shallower end of the second groove is less than the depth of the upper end of the first groove. The drive mechanism includes: A drive rod is slidably mounted vertically on the frame, and the drive rod is located on one side of the rotating base; A sliding pin, slidably mounted on the drive rod, has a ball-head end that elastically abuts against the first and second grooves and slides within them. The sliding pin can enter or exit from both ends of the first groove. A drive assembly for driving the drive rod to slide vertically.

[0009] Preferably, the lower end of the drive rod has a third hole; the ball end of the sliding pin passes through the third hole and abuts against the corresponding first groove; The drive mechanism also includes: The limiting block is connected to the end of the sliding pin away from the rotating seat; and A spring is sleeved on the sliding pin, and the two ends of the spring abut against the drive rod and the limiting block, respectively.

[0010] Preferably, the drive mechanism further includes: A push plate, connected to the drive rod, is located above the transmission plate, with its end away from the drive rod abutting against the end of the transmission plate; and The lifting plate, connected to the drive rod, is located below the transmission plate, and its end away from the drive rod can abut against the end of the transmission plate.

[0011] Preferably, the drive rod has a fourth hole in the vertical direction; The driving component includes: The motor is mounted on the frame; and The shaft has one end connected to the output end of the motor and the other end threadedly connected to the fourth hole.

[0012] Compared with the prior art, the present invention has the following beneficial effects: In this embodiment of the invention, different drugs are placed in different drug injection mechanisms. The rotating seat is driven by a driving device to rotate so that the different drug injection mechanisms are rotated sequentially above the gene chip. The drugs in the drug injection mechanisms are then quantitatively injected downwards onto the gene chip, thereby reducing operational requirements and improving sequencing efficiency. Attached Figure Description

[0013] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the accompanying drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn to scale.

[0014] Figure 1 This is a perspective view of a gene sequencer according to an embodiment of the present invention; Figure 2 for Figure 1 A three-dimensional view of the coordination between the drive unit and the drug injection mechanism; Figure 3 for Figure 2 A sectional view; Figure 4 for Figure 2 Another 3D image; Figure 5 for Figure 2 A three-dimensional view of the central transmission mechanism; Figure 6 for Figure 5 A three-dimensional view of the engagement between the transmission rod and the locking block; Figure 7 for Figure 3 Enlarged view of point A in the middle; Figure 8 for Figure 7 Enlarged view of section B in the middle.

[0015] Figure label: 10. Frame; 11. Fourth hole; 20. Rotary seat; 21. First hole; 22. Limiting ring; 23. First groove; 24. Second groove; 30. Drug injection mechanism; 31. Cylinder; 32. Needle; 33. Piston; 40. Clamping assembly; 50. Drive unit; 60. Drive mechanism; 61. Drive rod; 611. Third hole; 62. Sliding pin; 63. Drive assembly; 631. Motor; 632. Rotating shaft; 64. Limit block; 65. Spring; 66. Push plate; 67. Lifting plate; 70. Transmission mechanism; 71. Transmission plate; 711. Second hole; 72. Transmission rod; 721. Locking groove; 73. Mounting base; 74. Locking block; 741. Connecting end; 742. Suspension end; 743. Locking end. Detailed Implementation

[0016] The embodiments of the technical solution of the present invention will now be described in detail with reference to the accompanying drawings. These embodiments are merely illustrative of the technical solution of the present invention and are therefore intended to limit the scope of protection of the present invention.

[0017] It should be noted that, unless otherwise stated, the technical or scientific terms used in this application should have the ordinary meaning as understood by one of ordinary skill in the art to which this invention pertains.

[0018] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.

[0019] Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly defined.

[0020] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0021] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0022] See Figures 1 to 8 This embodiment provides a gene sequencer, including a frame 10, a rotating base 20, a drug injection mechanism 30, a clamping assembly 40, and a driving device 50.

[0023] The rotating base 20 is rotatably mounted on the frame 10. Multiple drug injection mechanisms 30 are provided, circumferentially distributed on the rotating base 20, and are used to load drugs. A clamping assembly 40 is mounted on the frame 10, located directly below one of the drug injection mechanisms 30, and is used to clamp the gene chip. The clamping assembly 40 can be configured according to existing technology. A driving device 50 is used to drive the rotating base 20 to rotate, and also to drive the drug injection mechanisms 30 to quantitatively inject drugs downwards onto the gene chip.

[0024] In gene sequencing, manual sample loading means adding the sequencing reagents to the gene chip in the required amount.

[0025] In this embodiment, different drugs are placed in different drug injection mechanisms 30. The rotating seat 20 is driven by the driving device 50 to rotate sequentially above the gene chip, and the drugs within each mechanism are quantitatively injected downwards onto the gene chip, thereby reducing operational requirements and improving sequencing efficiency. Furthermore, the rotation of the rotating seat 20 moves the different drug injection mechanisms 30 sequentially above the gene chip, forming a compact structure. This arrangement allows the rotating seat 20 to rotate in one direction during use, enabling the immediate activation of the next (or first) drug injection mechanism 30 after the last one has been used, resulting in better efficiency. Since the driving device 50 quantitatively injects drugs into the gene chip through the drug injection mechanisms 30, drug usage is better controlled, saving drugs.

[0026] In one embodiment, the rotating base 20 has a plurality of first holes 21 distributed circumferentially, the first holes 21 extending vertically through, and each first hole 21 has an inwardly contracting limiting ring 22 at its lower end.

[0027] The drug injection mechanism 30 includes a cylinder 31, a needle 32, and a piston 33.

[0028] The drug injection mechanism 30 can be configured similarly to a syringe.

[0029] The cylinder 31 is mounted on the rotating base 20, with its lower end inserted into the corresponding first hole 21 and abutting against the limiting ring 22. The needle 32 is connected to the lower end of the cylinder 31 and can rotate with the rotating base 20 to move above the gene chip. The piston 33 is slidably disposed within the cylinder 31, and dynamically seals against the inner wall of the cylinder 31. The driving device 50 can drive the piston 33 to slide within the cylinder 31.

[0030] In this embodiment, gene sequencing reagents are added into the cylinder 31, and the piston 33 is driven downward by the driving device 50 to slide a specified distance, thereby pushing the reagents from the needle 32 onto the gene chip below.

[0031] In one embodiment, the drive device 50 includes a drive mechanism 60 and a plurality of transmission mechanisms 70, each transmission mechanism 70 corresponding to a cylinder 31.

[0032] The transmission mechanism 70 includes a transmission plate 71, a transmission rod 72, a mounting base 73, and a locking block 74.

[0033] A second hole 711 is provided on the transmission plate 71, which is slidably mounted on the rotating seat 20 along the vertical direction. The transmission rod 72 is connected to the corresponding piston 33. The transmission rod 72 has a plurality of locking grooves 721 evenly distributed vertically, arranged in a row in the vertical direction. At least one row of locking grooves 721 is provided on each transmission rod 72. The mounting seat 73 is provided on the transmission plate 71, and the number of mounting seats 73 is equal to the number of rows of locking grooves 721. The locking block 74 has a connecting end 741, a hanging end 742, and a locking end 743. The connecting end 741 of the locking block 74 is rotatably connected to the mounting seat 73. The hanging end 742 of the locking block 74 is located below the connecting end 741 of the locking block 74. The locking end 743 of the locking block 74 is located on one side of the line connecting its connecting end 741 and hanging end 742. The locking end 743 of the locking block 74 abuts against the outer wall of the transmission rod 72 and can be inserted into the corresponding locking groove 721. Specifically, the suspended end 742 of the locking block 74 is located directly below its connecting end 741. Under the gravity of the locking block 74, the locking block 74 abuts against the side wall of the transmission rod 72. Once the locking end 743 of the locking block 74 passes through the locking groove 721, it will be inserted into the locking groove 721.

[0034] The distance from the connecting end 741 to the locking end 743 of the locking block 74 is greater than the distance from the connecting end 741 to the transmission rod 72, and the distance from the locking end 743 to the suspended end 742 is less than the distance to the connecting end 741. When the locking block 74 moves upward relative to the transmission rod 72, the locking block 74 passes through multiple locking slots 721 in sequence. When the locking block 74 moves downward relative to the transmission rod 72, the locking end 743 of the locking block 74 inserts into the nearest locking slot 721, thus connecting the locking block 74 to the transmission rod 72. The drive mechanism 60 is used to drive the transmission plate 71 to slide up and down. The drive mechanism 60 is also used to drive the rotating seat 20 to rotate.

[0035] In this embodiment, when the drive mechanism 60 moves the transmission plate 71 downward, the locking end 743 of the locking block 74 inserts into the locking groove 721, thereby moving the transmission rod 72 downward and thus realizing the injection of the medicine in the cylinder 31. Then, when the drive mechanism 60 moves the transmission plate 71 upward, the locking block 74 disengages from the transmission rod 72 until the transmission plate 71 returns to its position before the medicine injection. That is, after each medicine injection, the transmission plate 71 resets, which means that only the amount of medicine injected needs to be considered each time, without needing to consider the influence of the movement of the transmission rod 72 during the previous injection on the current injection, thereby improving the accuracy of quantitative medicine injection.

[0036] In one embodiment, the multiple locking slots 721 evenly distributed vertically on the transmission rod 72 form a row; the locking slots 721 on the transmission rod 72 have two or more rows; the number of mounting seats 73 and the number of locking blocks 74 correspond to the number of rows of locking slots 721; the locking slots 721 in different rows are staggered vertically. (Refer to...) Figure 5 and Figure 6 The two vertical locking slots 721 are arranged in an alternating pattern, ensuring that at least one of the locking blocks 74 on each side will insert into its corresponding locking slot 721 before the transmission rod 72 moves downward. That is, when the transmission plate 71 moves downward, one locking block 74 will insert into its locking slot 721 before the others, thus driving the transmission rod 72 downward and pushing the piston 33. This results in less play between the locking block 74 and the locking slot 721, creating a tighter connection. Consequently, the transmission rod 72 can also move downward promptly with each movement of the transmission plate 71, improving the accuracy of drug injection.

[0037] In one embodiment, the rotating base 20 is cylindrical. The axis of the rotating base 20 is parallel to the axis of the first hole 21. A vertical first groove 23 is formed on the outer wall of the rotating base 20 corresponding to each first hole 21, and an inclined second groove 24 is formed between two adjacent first grooves 23. The second groove 24 has a deeper end and a shallower end. The deeper end of the second groove 24 communicates with the lower end of an adjacent first groove 23, and the depth of the deeper end of the second groove 24 is greater than the depth of the lower end of the first groove 23. The shallower end of the second groove 24 communicates with the upper end of another adjacent first groove 23, and the depth of the shallower end of the second groove 24 is less than the depth of the upper end of the first groove 23.

[0038] The drive mechanism 60 includes a drive rod 61, a sliding pin 62, and a drive assembly 63.

[0039] A drive rod 61 is vertically slidably mounted on the frame 10, located on one side of the rotating base 20. A sliding pin 62 is slidably mounted on the drive rod 61. The sliding pin 62 has a ball end, which can elastically abut against the first groove 23 and the second groove 24 and slide. The sliding pin 62 can enter or leave from both ends of the first groove 23. Specifically, the lower end of the first groove 23 and the deeper end of the second groove 24 are in communication with the outside, and the ball end of the sliding pin 62 can disengage from the rotating base 20 from these points. The drive assembly 63 is used to drive the drive rod 61 to slide vertically.

[0040] In this embodiment, driven by the drive assembly 63, the vertical sliding of the drive rod 61 can drive the sliding pin 62 to slide vertically. When the sliding pin 62 is at the upper end of the first groove 23, the ball end of the sliding pin 62 abuts against the first groove 23; when the sliding pin 62 moves down to the lower end of the first groove 23 and slides into the deeper end of the second groove 24, the sliding pin 62 is subjected to elastic force, and the ball end of the sliding pin 62 abuts against the guide second groove 24. At this time, the sliding pin 62 can move downward to disengage from the rotating seat 20, and the sliding pin 62 can slide upward along the second groove 24 until it slides into the upper end of another first groove 23. The sliding of the sliding pin 62 along the second groove 24 can drive the rotating seat 20 to rotate. When the sliding pin 62 enters the deeper end of the second groove 24 of the rotating seat 20 from below, the ball end of the sliding pin 62 abuts against the bottom of the second groove 24, and the sliding pin 62 moves backward.

[0041] In one embodiment, the lower end of the drive rod 61 has a third hole 611, and the ball end of the sliding pin 62 passes through the third hole 611 and abuts against the corresponding first groove 23.

[0042] The drive mechanism 60 also includes a limit block 64 and a spring 65.

[0043] The limiting block 64 is connected to the end of the sliding pin 62 away from the rotating seat 20. The spring 65 is sleeved on the sliding pin 62, and the two ends of the spring 65 abut against the drive rod 61 and the limiting block 64 respectively. The drive rod 61 is located between the limiting block 64 and the rotating seat 20.

[0044] In one embodiment, the drive mechanism 60 further includes a push plate 66 and a lifting plate 67.

[0045] The injection plate 66 is connected to the drive rod 61 and is located above the transmission plate 71. The end of the injection plate 66 away from the drive rod 61 can abut against the end of the transmission plate 71. The lifting plate 67 is connected to the drive rod 61 and is located below the transmission plate 71. The end of the lifting plate 67 away from the drive rod 61 can abut against the end of the transmission plate 71.

[0046] In this embodiment, in the initial position, the upper end of the lifting plate 67 abuts against the lower end of the transmission plate 71, and the sliding pin 62 is located at the upper end of the first groove 23. As the drive rod 61 moves downward, the ball end of the sliding pin 62 slides along the first groove 23 to the bottom of the first groove 23, and then disengages from the rotating seat 20. At this time, the injection plate 66 abuts against the transmission plate 71. As the drive rod 61 moves further downward, the injection plate 66 drives the transmission plate 71 to move downward, and the medicine begins to be injected. After the injection is completed, the drive rod 61 moves upward, the injection plate 66 disengages from the transmission plate 71, and the sliding pin 62 moves upward to the deeper end of the second groove 24 (the lower end of the first groove 23). Then the sliding pin 62 moves further upward, and the rotating seat 20 rotates. During this process, the lifting plate 67 abuts against the transmission plate 71, driving the transmission plate 71 back to the initial position. At this time, the sliding pin 62 has moved to the upper end of the first groove 23.

[0047] In one embodiment, the drive rod 61 has a fourth hole 11 along the vertical direction.

[0048] The drive assembly 63 includes a motor 631 and a rotating shaft 632.

[0049] Motor 631 is mounted on frame 10. One end of shaft 632 is connected to the output end of motor 631, and the other end of shaft 632 is threaded to fourth hole 11. Specifically, a dovetail block is connected to the end of drive rod 61 away from rotating seat 20. Frame 10 includes a vertically arranged cantilever with a dovetail groove. The dovetail block slides into the dovetail groove, allowing drive rod 61 to slide vertically on frame 10.

[0050] Numerous specific details are set forth in this specification. However, it will be understood that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures, and techniques have not been shown in detail so as not to obscure the understanding of this specification.

[0051] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered within the scope of the claims and specification of the present invention.

Claims

1. A gene sequencer, characterized in that, include: Rack (10): Rotary seat (20), the rotary seat (20) is rotatably mounted on the frame (10), the rotary seat (20) has a plurality of first holes (21) distributed along the circumference, the first holes (21) penetrate vertically, and each first hole (21) has an inwardly contracting limiting ring (22) at its lower end. A drug injection mechanism (30) is provided in multiple ways. The multiple drug injection mechanisms (30) are arranged circumferentially on the rotating seat (20). The drug injection mechanism (30) is used to load drugs. The drug injection mechanism (30) includes a cylinder (31), a needle (32) and a piston (33). The cylinder (31) is arranged on the rotating seat (20). The lower end of the cylinder (31) is inserted into the corresponding first hole (21) and abuts against the limiting ring (22). The needle (32) is connected to the lower end of the cylinder (31). The needle (32) can rotate and move above the gene chip with the rotating seat (20). The piston (33) is slidably arranged in the cylinder (31). The piston (33) is dynamically sealed with the inner wall of the cylinder (31). A clamping assembly (40) disposed on the frame (10), the clamping assembly (40) being located directly below one of the drug injection mechanisms (30), the clamping assembly (40) being used to clamp the gene chip; and A drive device (50) is used to drive the rotating seat (20) to rotate, and the drive device (50) is also used to drive the piston (33) to slide inside the cylinder (31); The drive device (50) includes a drive mechanism (60) and a plurality of transmission mechanisms (70); each of the transmission mechanisms (70) corresponds to one of the cylinders (31); The transmission mechanism (70) includes: A transmission plate (71), on which a second hole (711) is provided, the transmission plate (71) being vertically slidably mounted on the rotating seat (20); and The transmission rod (72) is connected to the corresponding piston (33), and the transmission rod (72) has a plurality of locking grooves (721) evenly distributed in the vertical direction. The rotating seat (20) is cylindrical; the axis of the rotating seat (20) is parallel to the axis of the first hole (21); a first groove (23) is formed on the outer wall of the rotating seat (20) corresponding to each of the first holes (21); an inclined second groove (24) is formed between two adjacent first grooves (23); the second groove (24) has a deeper end and a shallower end; the deeper end of the second groove (24) is connected to the lower end of an adjacent first groove (23), and the depth of the deeper end of the second groove (24) is greater than the depth of the lower end of the first groove (23); the shallower end of the second groove (24) is connected to the upper end of another adjacent first groove (23), and the depth of the shallower end of the second groove (24) is less than the depth of the upper end of the first groove (23); The drive mechanism (60) includes: A drive rod (61) is slidably mounted on the frame (10) in a vertical direction, and the drive rod (61) is located on one side of the rotating seat (20); A sliding pin (62) is slidably disposed on the drive rod (61). The sliding pin (62) has a ball end. The ball end of the sliding pin (62) can elastically abut against the first groove (23) and the second groove (24) and slide. The sliding pin (62) can enter or leave from the upper and lower ends of the first groove (23). A drive assembly (63) is used to drive the drive rod (61) to slide vertically; A push plate (66), connected to the drive rod (61), is located above the transmission plate (71), with one end away from the drive rod (61) abutting against the end of the transmission plate (71); and The lifting plate (67) is connected to the drive rod (61) and is located below the transmission plate (71). One end of the lifting plate (67) away from the drive rod (61) can abut against the end of the transmission plate (71). The lower end of the drive rod (61) has a third hole (611); the ball end of the sliding pin (62) passes through the third hole (611) and abuts against the corresponding first groove (23).

2. A gene sequencer as described in claim 1, characterized in that, The transmission mechanism (70) further includes: Mounting base (73) is disposed on the transmission plate (71); and The locking block (74) has a connecting end (741), a hanging end (742) and a locking end (743). The connecting end (741) of the locking block (74) is rotatably connected to the mounting base (73). The hanging end (742) of the locking block (74) is located below the connecting end (741) of the locking block (74). The locking end (743) of the locking block (74) is located on one side of the line connecting its connecting end (741) and the hanging end (742). The locking end (743) of the locking block (74) abuts against the outer wall of the transmission rod (72) and can be inserted into the corresponding locking groove (721). The distance from the connecting end (741) of the locking block (74) to the locking end (743) of the locking block (74) is greater than the distance between the connecting end (741) of the locking block (74) and the transmission rod (72); the driving mechanism (60) is used to drive the transmission plate (71) to slide up and down; the driving mechanism (60) is also used to drive the rotating seat (20) to rotate; The multiple locking slots (721) evenly distributed vertically on the transmission rod (72) form a row; the locking slots (721) on the transmission rod (72) have two or more rows; the number of mounting seats (73) and the number of locking blocks (74) correspond to the number of rows of locking slots (721); the locking slots (721) in different rows are staggered vertically.

3. A gene sequencer as described in claim 2, characterized in that, The drive mechanism (60) further includes: The limiting block (64) is connected to the end of the sliding pin (62) away from the rotating seat (20); and A spring (65) is sleeved on the sliding pin (62), and the two ends of the spring (65) abut against the drive rod (61) and the limiting block (64) respectively.

4. A gene sequencer as described in claim 3, characterized in that, The drive rod (61) has a fourth hole (11) in the vertical direction. The driving component (63) includes: Motor (631), mounted on the frame (10); and The rotating shaft (632) has one end connected to the output end of the motor (631) and the other end threadedly connected to the fourth hole (11).

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