一株植物乳植杆菌及其在发酵槐花缓解高尿酸血症中的应用
Fermentation broth was prepared by fermenting Sophora japonica flowers with Lactobacillus plantarum WH-JS4, which solved the problems of large side effects in the treatment of hyperuricemia and the limitations of Sophora japonica flower application, and achieved safe and effective uric acid reduction and antioxidant effects.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SOUTH CHINA UNIV OF TECH
- Filing Date
- 2025-01-06
- Publication Date
- 2026-07-17
AI Technical Summary
Existing treatment strategies for hyperuricemia have problems such as significant side effects and poor compliance. Furthermore, medicinal and edible substances such as Sophora japonica flowers have limitations in practical applications, including large molecular weight, large size, low bioavailability, and poor taste.
Sophora japonica flowers were fermented using Lactiplantibacillus plantarum WH-JS4 to release or transform the active ingredients in the flowers during the fermentation process, and a Sophora japonica flower fermentation broth was prepared for the prevention and treatment of hyperuricemia.
It significantly reduces uric acid levels in hyperuricemic mice, improves kidney and liver function, enhances antioxidant enzyme activity, reduces inflammation, and decreases kidney and jejunal damage, providing a safe and effective treatment option.
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Figure CN120082459B_ABST