一株植物乳植杆菌及其在发酵槐花缓解高尿酸血症中的应用

Fermentation broth was prepared by fermenting Sophora japonica flowers with Lactobacillus plantarum WH-JS4, which solved the problems of large side effects in the treatment of hyperuricemia and the limitations of Sophora japonica flower application, and achieved safe and effective uric acid reduction and antioxidant effects.

CN120082459BActive Publication Date: 2026-07-17SOUTH CHINA UNIV OF TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTH CHINA UNIV OF TECH
Filing Date
2025-01-06
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing treatment strategies for hyperuricemia have problems such as significant side effects and poor compliance. Furthermore, medicinal and edible substances such as Sophora japonica flowers have limitations in practical applications, including large molecular weight, large size, low bioavailability, and poor taste.

Method used

Sophora japonica flowers were fermented using Lactiplantibacillus plantarum WH-JS4 to release or transform the active ingredients in the flowers during the fermentation process, and a Sophora japonica flower fermentation broth was prepared for the prevention and treatment of hyperuricemia.

Benefits of technology

It significantly reduces uric acid levels in hyperuricemic mice, improves kidney and liver function, enhances antioxidant enzyme activity, reduces inflammation, and decreases kidney and jejunal damage, providing a safe and effective treatment option.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开了一株植物乳植杆菌及其在发酵槐花缓解高尿酸血症中的应用。该植物乳植杆菌的名称为植物乳植杆菌(Lactiplantibacillus plantarum)WH‑JS4,已于2024年11月7日保藏于广州市先烈中路100号大院59号楼5楼的广东省微生物菌种保藏中心,保藏编号为:GDMCC No:65437。本发明中的植物乳植杆菌WH‑JS4可用于槐花发酵,经发酵获得的槐花发酵液具有良好降尿酸功效,可用于开发预防或治疗高尿酸血症的功能性产品。
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